Clinical trials: FLU
Immunization; Infection, Transplantation Infection
High vs. Standard Dose Influenza Vaccine in Adult SOT Recipients
The influenza virus is a significant cause of morbidity in adult solid organ transplant (SOT) recipients. However, these individuals show a suboptimal response to vaccines including the standard-dose (SD) inactivated influenza…
- Conditions
- Immunization; Infection, Transplantation Infection, Influenza, Solid Organ Transplant
- Trial name
- NCT04613206
- Testing
- High Dose Quadrivalent Inactivated Influenza Vaccine, Standard Dose Quadrivalent Inactivated Influenza Vaccine
- Where
- United States
- Volunteers
- 396 people
- Sponsor
- Vanderbilt University Medical Center
Influenza (Pandemic)
A/H5N1 Virus-Like Particle Antigen Dose Ranging Study With Adjuvant 1
The purpose of this study is to evaluate the immunogenicity and safety profile of the Avian flu vaccine with and without adjuvant 1 in healthy, young adults. The study is divided down into Parts A1, A2 and B.
- Trial name
- NCT01594320
- Testing
- Monovalent Avian Influenza VLP (H5N1), Monovalent Avian Influenza VLP (H5N1); Adjuvant
- Where
- 5 sites in United States
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- Novavax
Influenza -Like Illness
Norketotifen for the Treatment of Uncomplicated Influenza-like Illness
This is a Phase 2b, multi-center, double-blind, randomized, placebo-controlled, parallel-group study of NKT versus placebo in otherwise healthy adults presenting with acute uncomplicated ILI due to influenza or other respiratory…
- Trial name
- NCT04043923
- Testing
- Norketotifen
- Where
- 18 sites in United States
- Volunteers
- 238 people
- Sponsor
- Emergo Therapeutics, Inc.
COVID-19
A Study of an Investigational Flu Seasonal/SARS-CoV-2 Combination Vaccine in Adults
This study will evaluate the reactogenicity, safety, and immune response of Flu Seasonal/SARS-CoV-2 mRNA (mRNA Flu/COVID-19) combination vaccine.
- Trial name
- NCT06680375
- Testing
- Flu Seasonal /SARS-CoV-2 mRNA Dose 1, Flu Seasonal /SARS-CoV-2 mRNA Dose 2, Flu Seasonal mRNA
- Where
- 9 sites in United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Influenza, Human
Clinical Trials of Quadrivalent Influenza Vaccine
This clinical trial adopts a seamless design of phase I/II, conducted in two stages: phase I and phase II. Phase I is the age/dose ramp up stage, and phase II is the dose expansion stage.The purpose of this clinical trial is to…
- Trial name
- NCT06824519
- Testing
- Influenza Vaccine (Split Virion), Inactivated, Quadrivalent, ZFA02 Adjuvant (low dose), Influenza Vaccine (Split Virion), Inactivated, Quadrivalent, ZFA02 Adjuvant (high dose), Influenza Vaccine (Split Virion), Inactivated, Quadrivalent
- Where
- China
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Influenza, Behavior and Behavior Mechanisms
Nationwide Utilization of Danish Government Electronic Letter System for Increasing InFLUenza Vaccine Uptake Among Adults With Chronic Disease
In randomized clinical trials and observational studies, influenza vaccination has been shown to be effective in reducing influenza-related illness, hospitalizations, cardiovascular events, and mortality in select populations.
- Trial name
- NCT06030739
- Testing
- Behavioral Economic Principles
- Where
- Denmark
- Volunteers
- 299,881 people
- Sponsor
- Tor Biering-Sørensen
Influenza A
Safety, Tolerability, Efficacy and Immunogenicity of an Influenza A Vaccine (FP-01.1) in Healthy Volunteers Following Virus Challenge
The purpose of this study is to assess the safety, tolerability, efficacy, and immunogenicity of an influenza A vaccine (vaccine: FP-01.1), as compared to placebo, in healthy volunteers following a dose of influenza A virus.
- Trial name
- NCT02071329
- Testing
- Vaccine FP-01.1, Virus Challenge
- Where
- United Kingdom
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Immune Targeting Systems Ltd
Acute Upper Respiratory Tract Infection, Influenza
Kagocel® for the Prevention of ARVI and Influenza in Young People
This study evaluates the use of Kagocel for the prevention of acute respiratory viral infections (ARVI) and influenza during the epidemic rise in the incidence of diseases in Russia in 2018 (epidemiology: the number of cases…
- Conditions
- Acute Upper Respiratory Tract Infection, Influenza, Respiratory Viral Infection
- Trial name
- NCT04626622
- Testing
- Kagocel, No one
- Where
- Russia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Nearmedic Plus LLC
Healthy
A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial to Assess the Safety and Tolerability of Influenza Virus Vaccine,(CAIV-T) in Healthy Infants
Trial to compare the safety and tolerability of one and two doses of influenza virus vaccine.
- Trial name
- NCT00192348
- Testing
- CAIV-T
- Where
- Finland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
COVID-19, Influenza A
Clinical Evaluation of the Panbio™ COVID-19/Flu A&B Rapid Panel Professional Use Device and the Panbio™ COVID-19/Flu A&B Rapid Panel Self-Test Device
This study is designed as an international prospective, multicentric, clinical study to investigate the performance and usability of the Panbio™ COVID-19/Flu A\&B Rapid Panel Professional Use and Self- Test devices for the…
- Conditions
- COVID-19, Influenza A, Influenza Type B
- Trial name
- NCT05715515
- Testing
- Panbio™
- Where
- United States
- Volunteers
- 903 people
- Sponsor
- Abbott Rapid Dx
Influenza
Study of Nitazoxanide in Adults With Acute Uncomplicated Influenza
This is a randomized clinical trial designed to evaluate oral nitazoxanide compared to a placebo in the treatment of acute uncomplicated influenza in adults.
- Trial name
- NCT01056380
- Testing
- Nitazoxanide
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Romark Laboratories L.C.
Influenza
Ellume·Lab Flu A+B Test and the Ellume Home Flu Test Performance Versus Viral Culture and Reverse Transcriptase Polymerase Chain Reaction
The primary purpose of the study is to validate the sensitivity and specificity of the Ellume Home Flu Test and the ellume.lab Flu A+B Test in detecting influenza A and influenza B as compared to reverse transcriptase polymerase…
- Trial name
- NCT03595358
- Testing
- Ellume Home Flu Test, ellume.lab Flu A+B Test, Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)
- Where
- Australia
- Volunteers
- 25 people
- Sponsor
- Ellume Pty Ltd
Influenza
High-Dose Influenza Vaccine in Nursing Homes
The purpose of this study is to prospectively evaluate relative effectiveness of high dose influenza vaccine in preventing influenza mortality, hospitalization, and functional decline in a nursing home population in the U.S.…
- Trial name
- NCT01815268
- Testing
- HD Vaccine, SD Vaccine, Free Vaccine
- Where
- 3 sites in United States
- Volunteers
- 823 people, healthy volunteers welcome
- Sponsor
- Insight Therapeutics, LLC
Multiple Sclerosis
Aerobic Exercise and Flu-like Symptoms Following Interferon Beta 1a Injections in Patients With Multiple Sclerosis?
The purpose of the present study is to test the hypothesis that aerobic training can reduce flu-like symptoms following interferon beta 1a injections in patients with Multiple Sclerosis.
- Trial name
- NCT02236624
- Testing
- Aerobic exercise
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Influenza
A Study to Evaluate the Efficacy of GSK Biologicals' Influenza Vaccine in Children
This study is designed to test the efficacy of an investigational influenza vaccine, in children compared to Havrix®, a licensed Hepatitis A virus vaccine.
- Trial name
- NCT01218308
- Testing
- FluLaval® Quadrivalent, Havrix™
- Where
- 12 sites in Bangladesh, Dominican Republic and 6 more
- Volunteers
- 5,220 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Influenza and Acute Respiratory Viral Infections
Efficacy of Anaferon for Children in the Treatment of Influenza and Acute Respiratory Viral Infections in Children
The purpose of this study is: To obtain additional data on therapeutic efficacy of Anaferon for children in the treatment of influenza and acute respiratory viral infections in children
- Trial name
- NCT02072174
- Testing
- Anaferon for Children
- Where
- 27 sites in Belarus, Russia and 1 more
- Volunteers
- 569 people
- Sponsor
- Materia Medica Holding
Influenza H1N1
Non-specific Response to H1N1 Vaccine
This is a prospective observational study with recruitment of healthy volunteers from consecutive recipients of H1N1 influenza vaccine at the University Clinic of Respiratory and Allergic Diseases, Golnik, Slovenia.
- Trial name
- NCT01178918
- Where
- Slovenia
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- The University Clinic of Pulmonary and Allergic Diseases Golnik
Acute Respiratory Infections (ARIs), Influenza
Effect of Surgical Masks in Preventing Acute Respiratory Infections
The goal of this clinical trial is to evaluate the efficacy of surgical masks in preventing acute respiratory tract infections. The main question it aims to answer is: Does wearing a mask prevent you from getting acute…
- Conditions
- Acute Respiratory Infections (ARIs), Influenza, COVID - 19
- Trial name
- NCT07739446
- Testing
- Surgical masks
- Where
- Japan
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Chiba University
Healthy Volunteer
Systems Analyses of the Immune Response to the Seasonal Influenza Vaccine
Background: Vaccines help prevent disease by causing the body to have an immune response. Many parts of this response happen in the blood. This response happens over days and weeks after getting the vaccine.
- Trial name
- NCT04025580
- Testing
- Flucelvax, Fluvirin, Fluzone High Dose
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Lymphoma
Influenza Vaccination in Patients Receiving Antineoplastic Therapy for Non-Hodgkin's Lymphoma
Primary Objective: To assess the trend in immunogenic response across patients administered either licensed trivalent inactivated influenza vaccine (TIV) or one of three doses (15, 45 or 135 μg) of trivalent recombinant…
- Trial name
- NCT00307710
- Testing
- Trivalent Baculovirus-expressed Influenza HA vaccine
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- M.D. Anderson Cancer Center
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