Clinical trials: Face
Skin Laxity (Submental and Neck), Facial Skin Laxity
Safety and Effectiveness Evaluation of the High-intensity Focused Ultrasound Device for Lifting Lax Submental and Neck Tissue
This is a prospective, multicenter, randomized, evaluator-blinded, parallel-controlled, non-inferiority clinical study designed to evaluate the safety and effectiveness of the ULTRAFORMER MPT PLUS, a high-intensity focused…
- Conditions
- Skin Laxity (Submental and Neck), Facial Skin Laxity, Submental Tissue Laxity
- Trial name
- NCT07229430
- Testing
- ULTRAFORMER MPT PLUS, Ulthera System
- Where
- 5 sites in United States
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- CLASSYS Inc.
Atopic Dermatitis
Efficacy of KAM2904 Face Cream and KAM3008 Body Lotion Treatment in Children With Atopic Dermatitis (AD)
The main purpose of this study is to demonstrate the safety and efficacy of KAM2904 Face Cream and KAM3008 Body Lotion in reducing the symptoms of mild to moderate AD.
- Trial name
- NCT01781663
- Testing
- KAM2904 Face Cream, KAM3008 Body Lotion, petrolatum-based moisturizer
- Where
- Spain
- Volunteers
- 56 people
- Sponsor
- Kamedis Ltd.
Acne Vulgaris
Clinical Trial on the Effects and Side Effects of ProOxy in the Treatment of Acne
This study was conducted to determine the effects and side effects of ProOxy facial spray in the treatment of acne.
- Trial name
- NCT01682200
- Testing
- ProOxy
- Where
- 2 sites in Philippines
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medivet Pty Ltd
Cushing Syndrome
A Study of the Efficacy and Safety of Relacorilant in Patients With Endogenous Cushing Syndrome
This is a Phase 3, double-blind, placebo-controlled, randomized-withdrawal study to assess the efficacy, safety and pharmacokinetics (PK) of relacorilant in patients with endogenous Cushing syndrome and concurrent type 2 diabetes…
- Trial name
- GRACE (NCT03697109)
- Testing
- Relacorilant
- Where
- 64 sites in United States, Austria and 9 more
- Volunteers
- 152 people
- Sponsor
- Corcept Therapeutics
Facial Wrinkles, Skin Aging
A Study to Evaluate the Safety and Effectiveness of the Cryo-Touch II Device for the Treatment of Forehead and/or Glabellar Lines
A prospective, non-randomized, multicenter study to evaluate the safety and effectiveness of the cryo-touch II device for the treatment of forehead and/or glabellar lines
- Trial name
- NCT01447342
- Testing
- Cryo-Touch II
- Where
- 3 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Pacira Pharmaceuticals, Inc
Upper Facial Lines (Glabellar Lines, Forehead Lines, & Lateral Canthal Lines)
Recombinant Collagen Freeze-Dried Fibre for Upper Facial Wrinkles
The goal of this clinical trial was to learn whether a collagen filler improved facial wrinkles. The study product was injectable recombinant collagen freeze-dried fibers.
- Trial name
- NCT07897773
- Testing
- Recombinant Collagen Freeze-Dried Fibers, Collagen Implant
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Shaanxi Giant Biotechnology Co., Ltd
Facial Wrinkles, Rhytides
The Use of J-Plasma® for Dermal Resurfacing
This study evaluates the safety and effectiveness of J-Plasma in the reduction of facial wrinkles and rhytides. It is a multi-center, single arm, evaluator-blind prospective study of 55 study subjects who are seeking a procedure…
- Trial name
- NCT03286283
- Testing
- J-Plasma
- Where
- 3 sites in United States
- Volunteers
- 55 people
- Sponsor
- Apyx Medical
Photo-damage
Study to Evaluate the Safety and Efficacy of PEP005 (Ingenol Mebutate) Gel, 0.015%, in Patients With Photo-damaged Skin
This study is primarily designed to evaluate the safety and tolerability of PEP005 Gel, 0.015% when administered for up to three consecutive days to photo-damaged skin on the face.
- Trial name
- NCT01214577
- Testing
- PEP005 (ingenol mebutate) Gel
- Where
- 2 sites in Australia
- Volunteers
- 24 people
- Sponsor
- Peplin
Skin Aging
Effectiveness and Safety of Cellbooster Shape in Healthy Subjects
SUISSELLE has developed a CE marketed (2021) HA-based superficial epidermis/dermis injection filler and skinbooster product, Cellbooster® Shape (CBS). CBS is produced using patented CHAC Technology.
- Trial name
- NCT07636512
- Testing
- Skin booster injection (CBS)
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Suisselle
Aging
Subjects' Satisfaction on Pan Facial Aesthetic Enhancement After Treatment With Azzalure® and the Restylane® Range
The aim of this study is to assess subjects' satisfaction linked to the pan facial management of rejuvenation with injections of Azzalure® and Restylane® fillers. This will be an open, multi-centre study.
- Trial name
- FIRST (NCT01529203)
- Testing
- Botulinum Toxin Type A (Azzalure), Restylane ranges
- Where
- 5 sites in France, Spain and 1 more
- Volunteers
- 60 people
- Sponsor
- Galderma R&D
Acne Vulgaris
Bioequivalence Study of Adapalene Gel 0.3% in Subjects With Facial Acne Vulgaris
To evaluate the therapeutic equivalence and safety of Adapalene Gel 0.3% (Aleor Dermaceuticals Limited, India) and Differin® (Adapalene) Gel 0.3% (Galderma Laboratories, LP USA) in the treatment of acne vulgaris.
- Trial name
- NCT03650361
- Testing
- Adapalene Gel 0.3%, Differin 0.3% Topical Gel
- Where
- 10 sites in United States, Belize
- Volunteers
- 755 people
- Sponsor
- Aleor Dermaceuticals Limited
Acne Scars
Evaluation of Juläine (TM) for the Treatment of Atrophic Facial Acne Scars
This study aims to evaluate the effectiveness and safety of Juläine, an injectable medical device made of polylactic acid, for treating facial acne scars.
- Trial name
- NCT07058883
- Testing
- Juläine
- Where
- 2 sites in Poland
- Volunteers
- 55 people
- Sponsor
- Nordberg Medical AB
Dermatological Non-Disease
Effectiveness and Safety of Princess FILLER Lidocaine in Correction of Nasolabial Folds (NLF)
Clinical Investigation to demonstrate the effectiveness and safety of Princess Filler Lidocaine in the correction of moderate to severe nasolabial folds
- Trial name
- FILIDO (NCT03990883)
- Testing
- Princess Filler Lidocaine
- Where
- 11 sites in United States
- Volunteers
- 295 people
- Sponsor
- Croma-Pharma GmbH
Acne Vulgaris
A Phase 1 Study Assessing Local Cutaneous Effects of SB204
In this study, color (erythema) and pH will be measured on 3 consecutive days after application of 2 doses of SB204 to the cheeks of healthy volunteers.
- Trial name
- NCT02250430
- Testing
- SB204
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Novan, Inc.
Pain
Study Evaluating the Efficacy of an Ibuprofen Effervescent Tablet in the Treatment of Post-Surgical Dental Pain
Evaluation of the efficacy and safety of a single dose of an ibuprofen effervescent tablet in the treatment of pain following third molar extraction in comparison to single doses of placebo, standard ibuprofen tablets, and…
- Trial name
- NCT00631111
- Testing
- effervescent ibuprofen tablets, effervescent Aspirin plus Vitamin C tablets, ibuprofen tablets
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Peripheral Nerve Transections, Acute or Planned in Upper Extremity and Facial Nerves
NTX-001 to Repair Peripheral Nerve Transection(s)
The proposed use of NTX-001 for transections of upper extremity and facial peripheral nerves, acutely or planned.
- Trial name
- NCT05565846
- Testing
- NTX-001
- Where
- 2 sites in United States
- Sponsor
- Neuraptive Therapeutics Inc.
Immunodeficiency, Skeletal Abnormalities
European Alpha-Mannosidosis Participant
International, multicenter, observational, longitudinal monitoring study to investigate the prevalence of Alpha-Mannosidosis in participants at risk for Alpha-Mannosidosis.
- Conditions
- Immunodeficiency, Skeletal Abnormalities, Deafness, Mental Retardation
- Trial name
- EUMAP (NCT03651245)
- Where
- 19 sites in Germany, Switzerland
- Volunteers
- 667 people
- Sponsor
- CENTOGENE GmbH Rostock
Hypersensitive, Reactive and Intolerant Skin
IN-USE TOLERANCE STUDY UNDER DERMATOLOGICAL AND OPHTHALMOLOGICAL CONTROLS AND EFFICACY ASSESSMENT (Face Balm)
The aim of this study is to assess the dermatological and ophthalmological tolerance of the investigational product Baume visage / Face balm RV4942A - RY1985 after 21 days of twice daily use on the study areas, under normal…
- Conditions
- Hypersensitive, Reactive and Intolerant Skin, Redness-prone Skin, Stinger Subjects
- Trial name
- NCT05171556
- Testing
- Cosmetic product
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Atrophic Acne Scars
Pilot Study of Combination Treatment With Subcision, Human Adipose Tissue-Derived Exosomes and Powdered Polydioxanone for Atrophic Acne Scars
This pilot study compared two treatments for depressed acne scars: subcision alone and subcision followed by injections containing exosomes derived from human fat-derived stem cells and powdered polydioxanone (PDO).
- Trial name
- NCT07914322
- Testing
- Subcision, Human Adipose-Derived Stem Cell Exosomes and Powdered Polydioxanone
- Where
- Malaysia
- Volunteers
- 12 people
- Sponsor
- COSMEDICIAN AP SDN BHD
Perioral Dermatitis
A Study of Azelaic Acid (AzA) 15% in Topical Treatment of Mild to Moderate Perioral Dermatitis
The purpose of this study is to test the efficacy and safety of AzA 15% Gel in the treatment of mild to moderate perioral dermatitis.
- Trial name
- NCT00403949
- Testing
- Azelaic acid 15% gel, Non-active base from azelaic acid 15% gel
- Where
- 4 sites in Germany
- Volunteers
- 48 people
- Sponsor
- LEO Pharma