Clinical trials: Face
Mid-face Volume Deficiency
Clinical Investigation Evaluating the Safety and Feasibility of Adipearl
Adipearl is an injectable filler intended to be injected subcutaneously in the face.
- Trial name
- NCT06034522
- Testing
- Adipearl
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Volumina Medical S.A.
Actinic Keratosis
A Sequential Treatment Regimen of Cryotherapy and Picato® for the Treatment of Actinic Keratosis on the Face and Scalp
The purpose of this trial is to compare the rate of complete clearance of actinic keratosis (AK) using sequential cryotherapy and field treatment with PEP005 Gel compared to cryotherapy alone.
- Trial name
- NCT01541553
- Testing
- Cryotherapy, Vehicle, Ingenol metabute
- Where
- 35 sites in United States
- Volunteers
- 367 people
- Sponsor
- LEO Pharma
Facial Wrinkles
Cryo-Touch II for the Treatment of Wrinkles
This is a prospective, non-randomized study to evaluate the performance of the MyoScience Cryo-Touch II device for the treatment of wrinkles.
- Trial name
- NCT01167140
- Testing
- Cryo-Touch II
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Pacira Pharmaceuticals, Inc
Trigeminal Neuralgia
RP-008 in Combination With Daily Oral Varenicline for the Treatment of Trigeminal Neuralgia
The goal of this study is to evaluate if KRIYA-748 (RP-008) is safe, tolerable, and preliminary effective in treating trigeminal neuralgia (TN) when used in combination with varenicline tartrate.
- Trial name
- RELIEF (NCT07596485)
- Testing
- RP-008, Varenicline tartrate
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Kriya Therapeutics, Inc.
Lentigo, Solar Lentigo
Evaluation of the Tolerance (Main Objective) and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post-inflammatory Hyperpigmentation) on the Face
The goal of this clinical trial is to compare the 3 different prototype of cyto-selective cryotherapy devices (name of the devices : CRYONOVE) use in brown spots on the face of subject from different ethnicities.
- Conditions
- Lentigo, Solar Lentigo, Post Inflammatory Hyperpigmentation
- Trial name
- CS5_10B (NCT06305897)
- Testing
- CRYONOVE (EC14_4osc), CRYONOVE (EC+05_1osc), CRYONOVE (EC+05_2osc)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cryonove Pharma
Lymphedema, Lymphedema of Face
Clinical Lymphedema Evaluation - Advancing Reconstruction of Head and Neck Lymphatics With Symani
The objective of this study is to evaluate the Symani System's safety and effectiveness for microsurgical anastomosis during open lymphatic reconstruction in the head and neck.
- Conditions
- Lymphedema, Lymphedema of Face, Internal Lymphedema, External Lymphedema
- Trial name
- CLEAR (NCT07311876)
- Testing
- Symani Surgical System
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- MMI (Medical Microinstruments, Inc.)
Mid Face Volume Loss
Neuramis® Volume Lidocaine for Volume Augmentation in the Mid-Face
To evaluate the effectiveness and safety of Neuramis® Volume Lidocaine for volume augmentation in the mid-face.
- Trial name
- NCT03754413
- Testing
- experimental, comparator
- Where
- China
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Medy-Tox
Actinic Keratosis
Controlled Study of the Occurrence of Actinic Keratosis on the Face After Cryotherapy + Aminolevulinic Acid (ALA) Photodynamic Therapy
The purpose of this study is to determine if Levulan photodynamic therapy (PDT) is safe and effective in the treatment of actinic keratoses (AK) on the face, following treatment with liquid nitrogen cryotherapy.
- Trial name
- NCT02239679
- Testing
- Aminolevulinic Acid, Topical Solution Vehicle, BLU-U
- Where
- 8 sites in United States
- Volunteers
- 166 people
- Sponsor
- DUSA Pharmaceuticals, Inc.
To Verify Tissue Heating and Temperature Stability and Safety Throughout RF Treatment Duration Applied on the Face
Evaluation of Thermal Outcome and Safety of Nuera Tight RF System
The purpose of the study is to verify tissue heating, temperature stability and safety of the Nuera Tight RF device during and after treatment session applied on the face.
- Trial name
- NCT05957029
- Testing
- NuEra Tight RF system
- Where
- 2 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Wrinkle, Nasolabial Fold
RHA® 4 NLF Cannula
This is a randomized, controlled, single-blinded, within-subject (split-face), multicenter, prospective study to investigate whether RHA®4 injected in NLFs with a cannula is non-inferior to RHA®4 injected in NLFs with a sharp…
- Conditions
- Wrinkle, Nasolabial Fold, Aging
- Trial name
- NCT04754646
- Testing
- Split-face injection of RHA® 4 with a cannula into a single NLF., Split-face injection of RHA® 4 with a needle (TSK 27G x ½") into the contralateral NLF.
- Where
- 4 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Healthy, Skin Manifestations
Facial Skin Clinical and Microbial Profiling From Oral Probiotic Supplementation
The goal of this double-blind randomized clinical trial is to investigate the effects on the skin from oral intake of probiotic supplements in healthy adult men and women.
- Trial name
- NCT05597254
- Testing
- Probiotic with niacin and berry extract, Probiotic without niacin and berry extract
- Where
- Sweden
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Oriflame Cosmetics AB
Rosacea
Assess the Ability of MetroGel 1% to Deliver Moisture to Facial Skin After a Single Application
This eight-hour kinetic regression clinical study was conducted to assess the ability of MetroGel® 1% to deliver moisture to facial skin after a single application.
- Trial name
- NCT00436527
- Testing
- Metronidazole gel 1%
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Galderma R&D
Mid Facial Contour Deficiencies
A Single-Center, Open-Label, Exploratory Study of the Volumizing Effect of SCULPTRA Measured by Three Dimensional Digital Surface Imaging
Measure the mid-facial volumetric correction from SCULPTRA treatment, using three-dimensional digital surface imaging Determine the mean change from baseline in facial contour deficiency as measured by the Dermik Nasolabial…
- Trial name
- NCT00487474
- Testing
- DL6049 (injectable poly-L-lactic acid)
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Bausch Health Americas, Inc.
Acne Vulgaris
Efficacy and Safety Study of VB-1953 Topical Gel for Inflammatory Facial Acne Vulgaris
A Phase 2, Multicenter, Randomized, Double-Blind, Vehicle Controlled, Dose-ranging Study in the Treatment of Acne Vulgaris,
- Trial name
- NCT03900676
- Testing
- VB-1953 - 2%, VB-1953 - 0% (Vehicle)
- Where
- 12 sites in United States
- Volunteers
- 480 people
- Sponsor
- Vyome Therapeutics Inc.
Healthy, Trigeminal Neuralgia
PK and Safety Study of BIIB074 in Healthy Japanese and Caucasian Participants
The primary objectives of this study are: To evaluate pharmacokinetics (PK) properties of BIIB074 administered as a single oral dose in healthy Japanese and Caucasian participants; and To evaluate the PK properties of BIIB074…
- Trial name
- NCT02831517
- Testing
- BIIB074
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Biogen
Facial Skin Laxity
Clinical Study on the Application of a Non-Invasive Micro-Focused Ultrasound With Visualization System for Skin Laxity (ULT-215)
To evaluate the effect of the Ulthera® system for facial laxity and sagging skin
- Trial name
- ULT-215 (NCT03545412)
- Testing
- Microfocused ultrasound with visualization
- Volunteers
- 25 people
- Sponsor
- Ulthera, Inc
Senile Ptosis
Evaluation of Patient and Physician Satisfaction With the Zift eLevatIon of Facial Tissue Clinical Study
The LIFT study will document the first clinical use of the ZiftLift Tissue Anchor in a browlift for patients with age-related brow ptosis.
- Trial name
- LIFT (NCT03055819)
- Testing
- Brow Lift
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zift, LLC
Acne Vulgaris
Dapsone Gel 5% and Tretinoin Gel 0.025% Versus Tretinoin Gel 0.025% Monotherapy for Facial Acne Vulgaris
A 12-week evaluation of the safety and efficacy of dapsone gel 5% when used with tretinoin gel 0.025% compared with tretinoin gel 0.025% monotherapy in treating moderate to severe facial acne vulgaris
- Trial name
- NCT00835198
- Testing
- Dapsone; Tretinoin, Tretinoin
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- Allergan
Skin Irritation
Cetaphil® Daily Facial Moisturizer With Sunscreen SPF 50+ - Human Repeat Insult Patch Test
This study examined the possible sensitization and irritation effects of a moisturizer with sunscreen SPF 50+.
- Trial name
- NCT01892657
- Testing
- Facial Moisturizer with SPF 50+
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Face and Neck Wrinkles, Texture, Pigmentation
Lutronic Infini and LaseMD Systems in Combination Treatment
This is a prospective, multi-site, non-randomized study evaluating the safety and effectiveness of the Infini and LaseMD Systems for combination treatment in wrinkles, texture, and pigmentation of the face and/or neck.
- Trial name
- NCT03409965
- Testing
- Lutronic Infini System, Lutronic LaseMD System
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- CynosureLutronic