Clinical trials: Face
Nasolabial Fold Correction
Multicenter Study to Evaluate the Safety and Efficacy of Revanesse® Ultra Retreatment
To compare improvement with retreatment for all subjects undergoing correction of nasolabial folds (NLFs) in the initial SYM2014-02 study, who were retreated with Revanesse Ultra at Visit 6/Week 24 and to determine the safety of…
- Trial name
- Retreatment (NCT02984878)
- Testing
- Revanesse Ultra
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Prollenium Medical Technologies Inc.
Facial Wrinkles at the Nasolabial Folds
A Study to Compare the Safety and Effectiveness of a Non-FDA Approved Device Dermal Gel Extra (DGE) and an FDA Approved Device for the Correction of Nasolabial Folds (NLFs)
The purpose of this research study is to evaluate the safety and effectiveness of injection with DGE Injectable Gel (hyaluronic acid with lidocaine manufactured by Genzyme Biosurgery) as compared to injection with Restylane (a…
- Trial name
- NCT00444626
- Testing
- Dermal Gel Extra (DGE), Restylane, EMLA Cream
- Where
- 6 sites in United States
- Volunteers
- 140 people
- Sponsor
- Genzyme, a Sanofi Company
Dental Pain, Surgery, Dental
Dental Pain (Following Third Molar Tooth Extraction) Study
The purpose of this study is to evaluate the effectiveness of GW406381 (a COX-2 inhibitor) in treating the signs and symptoms of dental pain following third molar tooth extraction.
- Trial name
- NCT00114049
- Testing
- GW406381
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- GlaxoSmithKline
Facial Hyperpigmentation
Open-label, Single-arm, Proof of Concept Study in Subjects with Mild-to-moderate Facial Hyperpigmentation
This research study will test how well hyperpigmentation treatment works for subjects with mild-to-moderate facial hyperpigmentation. The study will also test if the hyperpigmentation treatment causes any irritation.
- Trial name
- K-BRIGHT (NCT06473974)
- Testing
- Test cosmetic product
- Where
- 2 sites in United States
- Sponsor
- Kayuraeffect, LLP
Trigeminal Neuralgia
RP-008 in Combination With Daily Oral Varenicline for the Treatment of Trigeminal Neuralgia
The goal of this study is to evaluate if KRIYA-748 (RP-008) is safe, tolerable, and preliminary effective in treating trigeminal neuralgia (TN) when used in combination with varenicline tartrate.
- Trial name
- RELIEF (NCT07596485)
- Testing
- RP-008, Varenicline tartrate
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Kriya Therapeutics, Inc.
Dental Anxiety, Dental Pain
Nonpharmacologic Reduction of Periprocedural Distress and Drug Use
Objectives of this Phase I pilot trial are to provide data towards assessing and facilitating feasibility of a larger scale Phase II trial in which the effects of a calmative Comfort Talk® app can be unequivocally evaluated.
- Conditions
- Dental Anxiety, Dental Pain, Drug Use, Opioid Use
- Trial name
- NCT03328208
- Testing
- Comfort Talk® app, White Noise app
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- Hypnalgesics, LLC
Burning Eye, Irritation; Eyeball
Vit-A-Vision® Clinical Investigation
Symptoms of ocular discomfort include dryness, burning, stinging, photophobia, foreign body sensation and contact lens intolerance.
- Conditions
- Burning Eye, Irritation; Eyeball, Tired Eye, Dry Eye Disease
- Trial name
- NCT06596733
- Testing
- Vit-A-Vision
- Where
- Germany
- Volunteers
- 77 people
- Sponsor
- OmniVision GmbH
Pain, Aging
RHA® Redensity With New Anesthetic Agent Perioral Rhytids (PAS)
This is a randomized, controlled, double-blinded, within-subject (split-face), multicenter, prospective study to investigate whether RHA® Redensity with new anesthetic agent is non-inferior to RHA® Redensity with lidocaine in…
- Trial name
- NCT06378086
- Testing
- RHA® Redensity with new anesthetic agent, RHA® Redensity with lidocaine
- Where
- 3 sites in United States, Puerto Rico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Skin Wrinkling
Emervel® Deep Lidocaine vs. Juvederm® Ultra Plus in Treatment of Moderate to Severe Facial Wrinkles and Folds
The purpose of the study was to compare the effectiveness and safety of Emervel Deep Lidocaine versus Juvederm Ultra Plus in the treatment of moderate to severe facial wrinkles and folds.
- Trial name
- NCT01205061
- Testing
- Emervel Deep Lidocaine, Juvederm Ultra Plus
- Where
- 11 sites in United States
- Volunteers
- 162 people
- Sponsor
- Galderma R&D
Healthy
Effect of Moisturizer on Malaysian Women Facial Skin
The goal of this clinical trial is to evaluate the effect of Product X on facial skin of middle-aged women in Malaysia. The main questions it aims to answer are: 1.
- Trial name
- NCT05657379
- Testing
- Other: Product X moisturizer
- Where
- Malaysia
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- USMARI Research & Innovation Centre
Atrophic Acne Scar
SkinPen Efficacy on Acne Scars on the Face and/or Back
This single-center, clinical trial will take place over a 90 day course followed by 1-month and 6-month post treatment visits to assess the efficacy and tolerability of the SkinPen device when used on both men and women on the…
- Trial name
- NCT02646917
- Testing
- Aesthetic Microneedling Treatment
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Bellus Medical, LLC
Facial Wrinkles, Skin Hydration
Study to Assess the Efficacy of EMC-CAP-2025A on Age-Related Skin Parameters in Healthy Individuals
The goal of this clinical study is to evaluate the efficacy and tolerability of EMC-CAP-2025A, an eggshell membrane-based dietary supplement, on age-related skin parameters in healthy adults.
- Conditions
- Facial Wrinkles, Skin Hydration, Skin Elasticity
- Trial name
- NCT07493850
- Testing
- EMC-CAP-2025A, EMC-CAP-2025B
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Circul'Egg
Wrinkles
Post Market Non-Interventional Study of Safety and Performance of RefillHA Volume
This study designed to evaluate the safety and performance of RefillHA Volume, a dermal filler for facial soft tissue augmentation and correction of facial wrinkles and folds in routine clinical setting.
- Trial name
- NCT07329608
- Where
- Israel
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Glyance
Atopic Dermatitis (AD)
EFFICACY AND TOLERANCE OF AN EMOLLIENT CREAM IN SKIN OF COLOR
The aim of this study is to evaluate the efficacy and tolerance of a face and body emollient cream in individuals (infants, children, adults) with phototypes IV-VI presenting mild to moderate atopic dermatitis (study under…
- Trial name
- NCT07839897
- Testing
- Emollient cream RV4660B
- Where
- Brazil
- Volunteers
- 59 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
Solar Lentigo, Senile Lentigo
Performance and Tolerance of Cyto-selective Difluoroethane-based Cryotherapy in th Treatment of Brown Spots (Solar and Senile Lentigines, Post-Inflammatory Hyperpigmentation) on the Face and Hands of Asian Ethnicity Skins
CS5_4 study aim to evaluate the performance and the tolerance of 3 prototypes of cyto-selective cryotherapy treatments applied on the brown spots on the face and hands of asian ethnicity skins (chinese).
- Trial name
- NCT05886010
- Testing
- prototypes 1 everyday, prototypes 1 every week, prototypes 1 every two weeks
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Cryonove Pharma
Acne Vulgaris
Safety, Efficacy and Pharmacokinetic Characteristics of KR230109 Cream in Facial Acne Vulgaris
This study will evaluate the safety, efficacy and pharmacokinetics of KR230109 cream compared with placebo in Patients (18-40 Years) with Acne vulgaris
- Trial name
- NCT07345390
- Testing
- KR230109 cream 0.025%, KR230109 cream 0.05%
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Jiangxi Kvvit Pharmaceutical Co., Ltd.
Obstructive Sleep Apnea
A Development Study to Evaluate a Full-Face Mask for the Treatment of Obstructive Sleep Apnea
This investigation is designed to evaluate the comfort, ease of use and performance of a trial nasal mask for the treatment of Obstructive Sleep Apnea (OSA) in the home environment.
- Trial name
- NCT03272763
- Testing
- F&P Toffee mask
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Fisher and Paykel Healthcare
Pain
S-Caine™ Peel (Skin Numbing Cream) to Treat Pain During Non-Ablative Facial Laser Resurfacing in Adults
Lasers are used for non-ablative resurfacing of facial rhytides, atrophic scars, and a variety of epidermal and dermal lesions. Pain associated with the non-ablative laser treatment has been described as moderate to severe.
- Trial name
- NCT00110747
- Testing
- S-Caine™ Peel (lidocaine and tetracaine topical cream 7%/7%)
- Where
- 3 sites in United States
- Volunteers
- 54 people
- Sponsor
- ZARS Pharma Inc.
Non-facial Skin Aesthetic Conditions
Sculptra Chart Review
Multi-center retrospective chart review to evaluate the safety of Sculptra Aesthetic when used in non-facial areas
- Trial name
- NCT05463978
- Testing
- Sculptra Aesthetic
- Where
- 8 sites in United States
- Volunteers
- 498 people
- Sponsor
- Galderma R&D
Mandibular Fractures, Facial Fracture
Stryker Facial iD Universal Plate Configurator: A Retrospective Post Market Follow Up
A retrospective post market follow up to confirm safety and performance of Stryker's Facial iD Universal Plate Configurator (UPC) implants in the clinical setting.
- Conditions
- Mandibular Fractures, Facial Fracture, Maxilla Fracture, Orthognathic Surgical Procedures
- Trial name
- UPC (NCT07245810)
- Testing
- Orthognatic surgery, Reconstructive maxillofacial surgery, Mandible and maxillofacial trauma surgery
- Where
- 2 sites in United States
- Volunteers
- 726 people
- Sponsor
- Stryker Craniomaxillofacial