Clinical trials: Face
Melasma
Efficacy and Tolerability of Test Product Versus Cysteamine 5% in Treatment of Facial Epidermal Melasma
This interventional, randomized, investigator blinded, controlled study conducted in one centre consists in a 4-month evaluation period within the same season avoiding sunny season on 140 subjects with facial epidermal melasma.
- Trial name
- NCT06278948
- Testing
- Group TP, Group CYS
- Where
- India
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Facial Wrinkles at the Nasolabial Folds
A Study to Compare the Safety and Effectiveness of a Non-FDA Approved Device Dermal Gel Extra (DGE) and an FDA Approved Device for the Correction of Nasolabial Folds (NLFs)
The purpose of this research study is to evaluate the safety and effectiveness of injection with DGE Injectable Gel (hyaluronic acid with lidocaine manufactured by Genzyme Biosurgery) as compared to injection with Restylane (a…
- Trial name
- NCT00444626
- Testing
- Dermal Gel Extra (DGE), Restylane, EMLA Cream
- Where
- 6 sites in United States
- Volunteers
- 140 people
- Sponsor
- Genzyme, a Sanofi Company
Pain
S-Caine™ Peel (Skin Numbing Cream) to Treat Pain During Non-Ablative Facial Laser Resurfacing in Adults
Lasers are used for non-ablative resurfacing of facial rhytides, atrophic scars, and a variety of epidermal and dermal lesions. Pain associated with the non-ablative laser treatment has been described as moderate to severe.
- Trial name
- NCT00110747
- Testing
- S-Caine™ Peel (lidocaine and tetracaine topical cream 7%/7%)
- Where
- 3 sites in United States
- Volunteers
- 54 people
- Sponsor
- ZARS Pharma Inc.
Trigeminal Neuralgia
Nasal Carbon Dioxide for the Symptomatic Treatment of Classical Trigeminal Neuralgia
A placebo-controlled, single-blind study to evaluate the safety and preliminary efficacy of nasal carbon dioxide for the symptomatic treatment of classical trigeminal neuralgia.
- Trial name
- NCT02473016
- Testing
- Carbon Dioxide Drug Delivery System (CDDS)
- Where
- 6 sites in United States
- Volunteers
- 30 people
- Sponsor
- Capnia, Inc.
Keratosis, Actinic
A Study of Tirbanibulin Ointment and Diclofenac Sodium Gel for the Treatment of Adult Participants With Actinic Keratosis on the Face or Scalp
The purpose of the study is to evaluate the incidence of biopsy confirmed invasive squamous cell carcinoma (SCC) in the selected treatment field (TF) after administration of topical tirbanibulin 10 milligram (mg)/gram (g)…
- Trial name
- AKtive (NCT05387525)
- Testing
- Tirbanibulin (Klisyri®) 10 mg/g ointment, Diclofenac Sodium 3% Gel
- Where
- 49 sites in France, Germany and 4 more
- Volunteers
- 447 people
- Sponsor
- Almirall, S.A.
Face; Atrophy
DA-13-007 Versus Sculptra for the Treatment of Nasolabial Folds Wrinkles
Study DA-13-007 is a randomized, evaluator-blinded, within subject (split face) multicenter clinical study of DA-13-007l (Injectable poly-l-lactic acid) compared to SCULPTRA in the treatment of nasolabial fold wrinkles.
- Trial name
- NCT02310490
- Testing
- DA-13-007 right with left side Sculptra left side, DA-13-007 left with left side Sculptra right side
- Where
- 4 sites in United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- DermAvance
Facial Atrophy
Adipose Derived Stem Cells in Facial Fat Grafting
This phase two, randomized, double-blind study is designed to demonstrate the enhanced efficacy of SVF-enriched autologous facial fat grafts, in relation to standard, non-SVF enriched, facial fat grafts by evaluating volumetric…
- Trial name
- SVF (NCT02526576)
- Testing
- Stromal Vasular Fraction, Biopsy
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Antria
Facial Atrophy and Loss of Contour
Open Label, Multi-Center Study, Evaluating the Effect of Adipose Tissue Processed With the SyntrFuge™ System for Facial Fat Grafting
This is an open label multi-center study with the aim of evaluating the efficacy of adipose tissue processed with the SyntrFuge™ system in facial aesthetics and contouring.
- Trial name
- NCT05522426
- Testing
- SyntrFuge System
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Syntr Health Technologies, Inc.
Actinic Keratosis
A Multi-center Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on the Head (Face or Scalp)
This Phase III study is designed to assess the efficacy and safety of PEP005 Gel, 0.015% when applied to an area of skin containing 4-8 AK lesions on the face or scalp.
- Trial name
- NCT00916006
- Testing
- PEP005 Gel, Vehicle gel
- Where
- 21 sites in United States, Australia
- Volunteers
- 269 people
- Sponsor
- Peplin
Nasolabial Folds, Mid Face Volume Loss
Evaluate the Post-marketing Efficacy and Safety of Eptq S and Eptq Lidocaine S
This study in multi-center, prospective and observational study. The purpose of this study is to observe effects and safety of hyaluronic acid filler series, eptq S and eptq Lidocaine S, for facial volume and folds.
- Conditions
- Nasolabial Folds, Mid Face Volume Loss, Lip Volume Enhancement
- Trial name
- NCT06699147
- Testing
- Hyaluronic Acid (HA)
- Where
- South Korea
- Volunteers
- 238 people
- Sponsor
- Jetema Co., Ltd.
Hyperpigmentation
Efficacy and Tolerability of Tested Formula After 3 Months in Treatment of Facial Hyperpigmentation of 3 Origins
The objective of this study is to evaluate the efficacy, cosmetic acceptability and improvement of the stigmatization of the tested product (2039125 03) used bis in die (BID) for 3 months in adult patients suffering from mild to…
- Trial name
- NCT06320314
- Testing
- tested product (2039125 03)
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Skin Diseases
A Five Day Clinical Study to Examine the Effects of a Benzoyl Peroxide Treatment on Facial Acne Lesions
5 Day study to assess how quickly a topical acne product begins to work.
- Trial name
- NCT02052752
- Testing
- 3% Benzoyl Peroxide, Neutrogena Rapid Clear®
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- GlaxoSmithKline
Facial Rhytides, Glabellar Rhytides
A Safety and Efficacy Study of OnabotulinumtoxinA in Upper Facial Rhytides
This is a safety and efficacy study of onabotulinumtoxinA in subjects with upper facial rhytides (forehead lines, glabellar lines, lateral canthal lines [crow's feet lines]).
- Trial name
- NCT02261493
- Testing
- OnabotulinumtoxinA, Normal Saline
- Where
- 24 sites in United States, Belgium and 2 more
- Volunteers
- 787 people
- Sponsor
- Allergan
Postoperative Facial Ecchymosis, Postoperative Facial Edema
Perioperative Photobiomodulation in Facial Plastic Surgery
This study is testing whether a new light therapy schedule can reduce bruising after facial plastic surgery, compared with the light therapy schedule currently used in the investigator's practice.
- Trial name
- CLEAR PBM (NCT07846631)
- Testing
- ELIXIR MD Photobiomodulation (PBM) System
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Elixir MD Inc
Toothache
Assessing the Analgesic Efficacy of Naproxen Sodium in Postsurgical Dental Pain.
To evaluate the analgesic efficacy of a single, oral dose of a naproxen sodium extended-release tablet, compared to placebo in postsurgical dental pain.
- Trial name
- NCT00720057
- Testing
- Naproxen Sodium ER (BAYH6689)
- Where
- 3 sites in United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Bayer
Acne Vulgaris
A Phase 4, Single-Blind, Randomized, Study to Compare the Tolerability and Efficacy of 0.1% Tazorac Cream When Used in Combination With Either Duac Gel or Acanya Gel for the Treatment of Facial Acne Vulgaris
A single-blind (investigator-blinded), randomized, parallel group, single center study to evaluate the tolerability and efficacy of combination therapy with Duac Gel / 0.1% Tazorac Cream and Acanya Gel / 0.1% Tazorac Cream for…
- Trial name
- C0000-411 (NCT01016977)
- Testing
- Clindamycin 1%/Benzoyl Peroxide 5% and 0.1% tazarotene, clindamycin phosphate 1.2%/benzoyl peroxide 2.5% and 0.1% tazarotene
- Volunteers
- 40 people
- Sponsor
- Stiefel, a GSK Company
Masseter Muscle Prominence
BOTOX® Treatment for Adults With a Wide Lower Face Due to Masseter Muscle Prominence
This study is designed to evaluate the safety and effectiveness of administering BOTOX for the treatment of Masseter Muscle Prominence (MMP) in adults.
- Trial name
- NCT04073303
- Testing
- Botulinum Toxin Type A
- Where
- 21 sites in Canada, China and 1 more
- Volunteers
- 377 people
- Sponsor
- AbbVie
Acne
Clinical Efficacy Evaluation of a Skincare Product for Acne Face, Upper Chest and Back Used by Multiphototype Population Under Dermatological Control
The present aims to confirm, under normal conditions of use, the IP's clinical efficacy in controlling acne on the face, upper chest, and back after 28 and 42 days of product use, as well as illustrate its efficacy through…
- Trial name
- NCT06786442
- Testing
- EFFACLAR DUO+M CREAM
- Where
- Brazil
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Acne Vulgaris
Non-Significant Risk Study of Sebacia Microparticles in the Treatment of Facial Acne Vulgaris
Prospective, randomized, controlled, parallel group clinical study with blinded assessment evaluating Sebacia Microparticles (SM) with Nd:Yag laser in facial inflammatory acne vulgaris
- Trial name
- NCT03303170
- Testing
- Sebacia Microparticles, Nd:Yag Laser
- Where
- 11 sites in United States
- Volunteers
- 168 people
- Sponsor
- Sebacia, Inc.
Use of the Vloc Suture, Elevation of the Mid-face
Use of V-Loc Suture for Mid-face Lifting in Short-flap Rhytidectomy
This study will evaluate and measure the Vloc suture's ability to elevate the mid-face when using a short flap, short incision technique in during a traditional face-lift.
- Trial name
- NCT02023307
- Testing
- V-Loc Suture
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Lifestyle Lift