Clinical trials: Face
Trigeminal Neuralgia
Postoperative Analgesia in Patients With Microvascular Decompression
Perioperative pain is caused by a variety of harmful factors through multiple mechanisms, therefore, reasonable postoperative analgesia should be combined with drugs or measures of different mechanism , which is called multimodal…
- Trial name
- NCT03152955
- Testing
- Ketamine, scalp nerve block, ondansetron
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Mandible Fracture, Post-operative Antibiotics
The MANTRA Trial (MANdibular TRauma and Antibiotic Use)
1. FULL TITLE OF THE PROJECT Should we use post-operative antibiotics following surgery for patients with mandible fractures? The MANTRA trial (MANdibular TRauma and Antibiotic use) 2.
- Trial name
- MANTRA (NCT05964140)
- Testing
- Different post-operative antibiotic regimens following surgical treatment of mandible fractures
- Where
- 2 sites in United Kingdom
- Volunteers
- 2,841 people
- Sponsor
- East Lancashire Hospitals NHS Trust
Wrinkles
A Clinical Study to Evaluate the Efficacy and Safety of YVOIRE Classic Plus Versus YVOIRE Classic in Nasolabial Fold Injection
The objective of this study was to evaluate the efficacy and safety of HA IDF plus (with lidocaine) injected in the nasolabial fold compared to HA IDF (without lidocaine).
- Trial name
- NCT02340091
- Testing
- HA IDF plus, HA IDF
- Volunteers
- 62 people
- Sponsor
- LG Life Sciences
Acne Scars
Comparison of 1550nm Fractional Laser Alone Versus in Combination With Microneedling for the Treatment of Acne Scars
Acne scarring is an unfortunate consequence of inflammatory acne vulgaris that often leads to significant cosmetic and psychosocial impacts.
- Trial name
- NCT03901417
- Testing
- Fraxel Restore (Non-ablative Fractional Laser), Fraxel Restore (Non-ablative fractional laser) and SkinPen (Microneedling Device)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Skin Aging, Facial Wrinkles
Study of the Subdermal Implant "Ultracol"
Study of the effectiveness of the medical device "Intradermal implant, sterile ULTRACOL based on polydioxanone (ULTRA V Co., Ltd., Korea) in the correction of skin contour defects.
- Conditions
- Skin Aging, Facial Wrinkles, Senile Skin Atrophy, Lipodystrophy
- Trial name
- NCT07617350
- Testing
- Administration of the prepared solution - 1 time Post injection observation - 30, 60, 160 days from the date of the first injection.
- Where
- Russia
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Estelab Clinic
Facial Photodamage
Efficacy of Methyl Aminolevulinate + Daylight in Patients With Facial Photodamage
Treatment of actinic damage has included multiple procedures but to date there is limited scientific evidence to support the preferential use of one of these therapies according to their efficacy, safety and pain tolerance by…
- Trial name
- NCT02139618
- Testing
- Methyl Aminolevulinate (MAL)
- Where
- Colombia
- Volunteers
- 60 people
- Sponsor
- Fundación Dermabase
Dermatochalasis of Upper Eyelid, Blepharoplasty
Perioperative Haemostasis, Procedure-Related Pain After Physiological or Pharmacological Modifications of Local Anaesthesia Around the Eyes
The goal of this clinical trial is to determine whether buffering, warming, or addition of hyaluronidase or tranexamic acid to lignocaine during eyelid injection of local anaesthesia reduce injection pain and procedure-related…
- Trial name
- P4LE (NCT07734740)
- Testing
- Sodium Bicarbonate (NaHCO3), Warmed lignocaine, Hyaluronidase Injection
- Where
- 3 sites in Hong Kong
- Volunteers
- 80 people
- Sponsor
- Prince of Wales Hospital, Shatin, Hong Kong
Temporomandibular Disorders, Orofacial Pain
Genetic Polymorphisms and Their Association With Temporomandibular Disorders
Temporomandibular disorders (TMD) are the most common orofacial pain disorders of non-dental origin with the prevalence of 6.1-10.2%, and incidence of 3.9%.
- Trial name
- GenPolTMD (NCT04694274)
- Testing
- stabilization splint, physical therapy
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Croatian Science Foundation
Obsessive-compulsive Disorder
Internet-based vs Face-to-face Cognitive Behavioural Therapy for Obsessive-compulsive Disorder
Randomized controlled non-inferiority trial comparing therapist-guided Internet-based Cognitive behavioral therapy (ICBT), self-guided ICBT, and individual face-to-face (f2f) CBT for Obsessive-Compulsive Disorder (OCD) in adults.
- Trial name
- NCT02541968
- Testing
- Cognitive-behavioral therapy (face-to-face), Internet-based Cognitive-behavioral therapy, Internet-based Cognitive-behavioral therapy without therapist support
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Karolinska Institutet
Skin Ageing, Facial Wrinkles
Clinical Study Evaluating the Safety and Effectiveness of the NIRA Laser M2.1 for the Treatment of Full-Face Wrinkles
This clinical trial evaluated the safety and effectiveness of the NIRA Laser M2.1, with or without a topical treatment, for the treatment of full-face wrinkles in adults.
- Conditions
- Skin Ageing, Facial Wrinkles, Acne, Skin Elasticity
- Trial name
- NCT07572331
- Testing
- NIRA Laser M2.1, Topical
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- NIRA Innovations Inc.
To Assess the Bone Healing in Fracture Mandible Defects
COMPARATIVE ANALYSIS OF INNOVATIVE BONE HEALING TECHNIQUES
the study intends to observe the outcome of interventions (concentrated growth factor with autograft and xenograft) used to expedite bone healing and adaptation with minimal side effects.
- Trial name
- NCT05480631
- Testing
- autograft, autograft with addition of concenterated growth factor, xenograft with concentrated growth factor
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Skin Aging, Facial Aging
Objective Evaluation of Intradermal MSC-Derived Exosome Therapy on Facial Skin Quality
This study aims to evaluate the potential effects of mesenchymal stem cell-derived suspended exosome therapy on facial skin quality using objective imaging analysis.
- Conditions
- Skin Aging, Facial Aging, Skin Quality
- Trial name
- NCT07466953
- Testing
- Mesenchymal Stem Cell-Derived Exosome
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mert Ersan
Aesthetics, Intradermal Injections
Clinical Evaluation of the Safety and Performance of a Filler in Correction of Mid-face Age-related Volume Deficit
Prospective, single center study, on healthy subjects to evaluate the aesthetic improvement of facial volume, effect on the restoration and/or augmentation in subjects with mid-face age-related volume deficit after injection of a…
- Trial name
- NCT04505319
- Testing
- DEFINISSE CORE FILLER
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Relife S.r.l.
Chronic Pain
Electrotherapy Combined With Neck Exercises for Non-Specific Neck Pain
Objectives: The objective of this study is to compare the effectiveness of telerehabilitation versus a face-to-face program in the therapeutic approach to non-specific neck pain through exercise and analgesic electrotherapy.
- Trial name
- NCT06842381
- Testing
- Telerehabilitation Program, Face to Face Program
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Adelaida María Castro-Sánchez
Acute Hypoxemic Respiratory Failure, High-Flow Nasal Oxygen Therapy
Effects of Face Mask Continuous Positive Airway Pressure Vs. Noninvasive Ventilation Vs. High-flow Nasal Oxygen on Intubation-free Survival in Acute Hypoxemic Respiratory Failure: the TRIPOD Randomized Clinical Trial
Acute hypoxemic respiratory failure (AHRF) is a common indication for admission to an intensive care unit (ICU), with mortality exceeding 50% in cases where invasive mechanical ventilation is needed.
- Conditions
- Acute Hypoxemic Respiratory Failure, High-Flow Nasal Oxygen Therapy, Noninvasive Ventilation, Continuous Positive Airway Pressure (CPAP)
- Trial name
- TRIPOD (NCT06795971)
- Testing
- Continuous Positive Airway Pressure, High-flow nasal oxygen, Non-invasive ventilation
- Where
- China
- Volunteers
- 1,300 people
- Sponsor
- Southeast University, China
Bell Palsy
MIME THERAPY vs MOTOR IMAGERY TECHNIQUE in Bell's Palsy
Bell's palsy, characterized by unilateral paralysis/paresis of facial muscles, is a condition with a significant impact on individuals' lives.
- Trial name
- NCT06340009
- Testing
- mime therapy, motor imagery
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Acne Vulgaris
A Phase 2 Study of ASC-J9 Cream in Acne Vulgaris
The purpose of this study is to evaluate if topical ASC-J9 cream is effective in treating acne.
- Trial name
- NCT00525499
- Testing
- ASC-J9 cream
- Where
- 10 sites in United States
- Volunteers
- 186 people
- Sponsor
- AndroScience Corp
Age-Related Atrophy
Use of AAM for Correction of Age Related Volume Deficits in the Face
The purpose of this study is to evaluate Allograft Adipose Matrix (AAM) in the face of people with age-related volume deficit - fat loss. AAM is a tissue used to correct fat loss.
- Trial name
- NCT03652844
- Testing
- AAM
- Where
- 3 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Musculoskeletal Transplant Foundation
Major Depressive Disorder
Biomarkers of Social Sensitivity in Major Depression
Major depression disorder (MDD) is a frequent and disabling mental disorder with great risk of recurrence and chronicity. Interpersonal factors are among the strongest predictors of the course and duration of an episode of…
- Trial name
- SENSO (NCT02214511)
- Testing
- emotional facial stimuli, Cyberball game
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Epidermal Melasma, Facial Hyperpigmentation
Topical Metformin Versus Triple Regimen for Epidermal Melasma
Melasma is a common skin condition that causes dark brown patches, mainly on sun-exposed areas of the face. It is often persistent, may recur after treatment, and can affect a person's quality of life.
- Trial name
- MET-MEL (NCT07779811)
- Testing
- Topical 30% metformin cream, Topical Triple Regimen
- Where
- Pakistan
- Volunteers
- 104 people
- Sponsor
- Combined Military Hospital, Pakistan
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