Clinical trials: Facet Joint Pain; Low Back Pain
Facet Joint Pain
A Multi-Site Study of the Zyga GlyDer Facet Restoration Device In Subjects With LUmbar FacET Pain Syndrome - DUET
A non-randomized, multi-site feasibility study to evaluate the safety of the Glyder Device in subjects with a history of lumbar facet joint disease (L2 to the sacrum) and successful neural ablation in which the facet joint is…
- Trial name
- DUET (NCT02179476)
- Testing
- Glyder
- Where
- 4 sites in United States
- Volunteers
- 2 people
- Sponsor
- Zyga Technology, Inc.
Chronic Low-back Pain
Cooled RFA vs Conventional RFA to Manage Chronic Facetogenic Low Back Pain
This study is being conducted to assess the relative effectiveness of radiofrequency neurotomy in subjects with chronic axial low back pain originating in the lumbar facet joints using the COOLIEF* Cooled Radiofrequency Probe as…
- Trial name
- Lumbar CvS (NCT04803149)
- Testing
- Cooled Radiofrequency, Conventional Radiofrequency
- Where
- 10 sites in United States
- Volunteers
- 79 people
- Sponsor
- Avanos Medical
Facet Joint Pain
Multimodal PT With and Without Proprioceptive Training in Lumber FJS
This will be a randomized clinical trial. The study will be conducted at Pakistan Railways General Hospital Rawalpindi and Riphah International Hospital Islamabad. Patients with FJS will be included.
- Trial name
- NCT05931653
- Testing
- Multimodal Physical therapy, Proprioceptive training along with and Multimodal Physical therapy
- Where
- 3 sites in Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Low Back Pain, Facet Joint Pain
Cryoneurolysis for Facet Mediated Chronic Low Back Pain
This is a single-center, randomized, pilot study in adult subjects with facet mediated CLBP. Thirty (30) subjects are planned for initial enrollment and will be randomized 1:1 to receive ioveraº medial branch cryoneurolysis or…
- Trial name
- NCT06016127
- Testing
- iovera system, Radiofrequency ablation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Medical Pain Management Services, PLLC
Low Back Pain
Effectiveness of Thoracic Facet Joint Nerve Blocks
1. To demonstrate whether: i. Facet joint nerve blocks have therapeutic value beyond the duration of local anesthetic effect. ii.
- Trial name
- NCT00355706
- Testing
- Thoracic facet joint nerve blocks
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Pain Management Center of Paducah
Non Specific Low Back Pain, Muscle Energy Technique
PRT vs MET in Non-Specific Low Back Pain With Facet Restriction
Objective:The study aimed to compare the effectiveness of Positional Release Technique (PRT) and Muscle Energy Technique (MET) in reducing pain and improving outcomes for patients suffering from non-specific low back pain…
- Trial name
- LBP (NCT07165249)
- Testing
- Positional release technique (PRT), Muscle energy technique
- Where
- Palestinian Territories
- Volunteers
- 36 people
- Sponsor
- Palestine Ahliya University
Low Back Pain, Osteoarthritis
Platelet-rich Plasma Infiltration Versus Corticosteroid Infiltration (Prednisolone) in Treatment of Lumbar Facet Joint Syndrome
The prevalence of low back pain is estimated at 90% . Recent studies have shown that 15% to 52% of back pain is attributable to facet joint syndrome .
- Trial name
- IAPRP (NCT05105256)
- Testing
- Prednisolone, Platelet-rich plasma
- Where
- France
- Volunteers
- 76 people
- Sponsor
- CHU de Reims
Chronic Low Back Pain
Genetic Predictors of Responsiveness to Radiofrequency Denervation in Chronic Low Back Pain
The Investigators have designed this exploratory study in patients suffering from zygapophysial joint mediated pain to investigate if a correlation exists between inter-individual genetic variability (genotype) with treatment…
- Trial name
- NCT02383524
- Testing
- Lumbar Radiofrequency Medial Branch Neurolysis
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Low Back Pain
FAcet-joint Injection Clinical and Cost-effective Trial
Lumbar facet-joints are small, paired joints in the low back that provide stability, integrity and flexibility of movement to the spine.
- Trial name
- FACET (NCT03339362)
- Testing
- Active Procedure
- Where
- 3 sites in United Kingdom
- Volunteers
- 9 people
- Sponsor
- Barts & The London NHS Trust
Lower Back Pain Chronic, Facet Joint Arthrosis
Evaluation of Pain Level Reduction After Low-dose Radiation in Symptomatic Facet Joint Arthritis
The goal of this clinical trial is to compare low-dose radiation therapy (LDRT) with intra-articular steroid injections in participants suffering from chronic lower back pain as cause of facet joint arthritis (FJA).
- Conditions
- Lower Back Pain Chronic, Facet Joint Arthrosis, Osteoarthritis, Spine
- Trial name
- LORAFA (NCT05852808)
- Testing
- Intra-articular steroid injections, Low-dose radiation therapy
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- Silvia Gomez Ordonez
Lumbar Spondylosis
Study Evaluating the Safety and Feasibility of Platelet-rich Plasma to Treat Facetogenic Low Back Pain
This study is being done to assess the safety of using the Angel Concentrated Platelet Rich Plasma System to process Platelet Rich Plasma (PRP) to treat arthritis of the low back (lumbar spondylosis).
- Trial name
- NCT05250947
- Testing
- Angel® Concentrated Platelet Rich Plasma System, Platelet Rich Plasma
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Matthew Pingree
Lower Back Pain
Using MRI Scans to Evaluate Spinal Manipulation
Lumbar spinal manipulation, or chiropractic adjusting, is thought to separate the surfaces of the spinal joints and thereby relieve lower back pain.
- Trial name
- NCT00070902
- Testing
- Lumbar side-posture spinal adjusting
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Facet Joint Pain; Low Back Pain
Platelet Rich Plasma (PRP) for Facet Mediated Lumbar Low Back Pain
Low back pain (LBP) is both the single most common cause of disability and the leading cause of visits when military personnel go to their primary care doctors.
- Trial name
- NCT04822753
- Testing
- Platelet Rich Plasma injection to the lumbar facet joint
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Womack Army Medical Center
Low Back Pain, Lumbar Facet Joint Pain
An Alternative Technique for Lumbar Medial Branch Radiofrequency: Comparison With the Empirical Technique
In spite that variable techniques for lumbar MBRF exists, the tunnel vision technique is widely recommended for exact radiofrequency needle placement.
- Conditions
- Low Back Pain, Lumbar Facet Joint Pain, Arthropathy
- Trial name
- MBRF LBP (NCT01300715)
- Testing
- lumbar medial branch radiofrequency neurotomy
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Bundang Hospital
Lower Back Pain of Disc Origin, Joint Facet Syndrome
Long-Term Evaluation of the Performance and Safety of the IntraSPINE® Interlaminar Implant in the Treatment of Lumbar Degenerative Disc Disease
This is an observational study designed as an extension of a prospective study conducted between 2012 and 2017. Patients who were originally enrolled in the initial study are being recontacted for follow-up assessment, including…
- Conditions
- Lower Back Pain of Disc Origin, Joint Facet Syndrome, Lumbar Canal Stenosis, Spinal Disease
- Trial name
- IntraLT (NCT07790328)
- Testing
- IntraSPINE
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Cousin Biotech
Chronic Lower Back Pain (CLBP), Lumbar Facet Joint Pain
Lumbar Facet Platelet-Rich Plasma Injection Versus Medial Branch Radiofrequency Ablation for Chronic Lumbar Facet-Mediated Pain
The first clinical research effort under this initiative is a pilot randomized controlled trial comparing intra-periarticular lumbar facet platelet-rich plasma (PRP) injection to standard-of-care medial branch radiofrequency…
- Trial name
- NCT07692737
- Testing
- Platelet Rich Plasma Joint Injection, Medial branch radiofrequency ablation
- Volunteers
- 30 people
- Sponsor
- The New England Baptist Hospital
Lumbar Degenerative Disc Disease, Lower Back Pain
Human Autograft Mesenchymal Stem Cell Mediated Stabilization of The Degenerative Lumbar Spine
Investigate the potential of tissue grafting that includes human mesenchymal stem cells in the repair and potential stabilization of the degenerative Lumbar disk and facet joint denovo and at the time of surgical reconstruction.
- Conditions
- Lumbar Degenerative Disc Disease, Lower Back Pain, Chronic Lower Back Pain
- Trial name
- NCT02529566
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Foundation for Spinal Research, Education and Humanitarian Care, Inc.
Low Back Pain, Zygapophyseal Joint Arthritis
Radiofrequency Treatments for Lumbar Facet Joint Pain Management
In this study, investigators compared the effectiveness of medial branch conventional radiofrequency application and combined radiofrequency application in patients with lumbar facet joint disease , focusing on pain scores.
- Trial name
- NCT06695481
- Testing
- Conventional RF, Combined RF
- Where
- Turkey (Türkiye)
- Volunteers
- 133 people
- Sponsor
- Hacettepe University
Low Back Pain, Mechanical, Facet Syndrome of Lumbar Spine
Comparative Evaluation of the Results of Facet Joint Injections
Low back pain affects 60 to 90% of the total population. It is one of the most common causes of disability in adults. Low back pain can be originated from a wide variety of structures, and the facet joint is one of these…
- Trial name
- NCT06325631
- Testing
- Intra-articular injection to lumbar facet joint
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Oznur Uzun
Chronic Low Back Pain, Lumbar Facet Joint Osteoarthritis
Ultrasound-Guided Lumbar Facet Joint Injections for Facet-Related Pain: A Randomized Comparison of Saline, Steroid, and 5% Dextrose
This study aims to evaluate the effectiveness of prolotherapy using 5% dextrose compared to steroid and saline injections in patients with lumbar facet joint-related low back pain.
- Trial name
- NCT07528794
- Testing
- Dextrose Injection, Steroid Injection, Saline Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital