Clinical trials: Facet Joint Pain
Facet Joint Pain, Facet Syndrome of Lumbar Spine
Injections in the Diagnosis and Treatment of Lumbar Facet Syndrome
In suspected facet joints pain, it is recommended to perform nerve blocks to establish the diagnosis with positive results being and indicator of successful of most permanent treatment of facet pain by rhizolysis.
- Conditions
- Facet Joint Pain, Facet Syndrome of Lumbar Spine, Facet Joints; Degeneration
- Trial name
- NCT03871192
- Testing
- FACET JOINT UNDER CT GUIDANCE, NERVE BLOCK UNDER CT GUIDANCE, FACET JOINT UNDER FLUOROSCOPY GUIDANCE
- Where
- 2 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Complejo Hospitalario Universitario de Granada
Low Back Pain
Effectiveness of Lumbar Facet Joint Nerve Blocks
1. To demonstrate whether: i. Facet joint nerve blocks have therapeutic value beyond the duration of local anesthetic effect. ii.
- Trial name
- NCT00355914
- Testing
- Lumbar Facet Joint Nerve Block
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Pain Management Center of Paducah
Chronic Low-back Pain, Facet Joint Pain
Cryoneurolysis Outcome on Pain Experience (COPE) in Patients With Low-back Pain
This study will provide information on the effectiveness of cryoneurolysis for patients with facet joint pain syndrome, and help to establish whether cryoneurolysis should be implemented in clinical practice for this patient…
- Conditions
- Chronic Low-back Pain, Facet Joint Pain, Degeneration Lumbar Spine, Facet Joint Syndrome
- Trial name
- COPE (NCT04786145)
- Testing
- Cryoneurolysis, Radiofrequency ablation
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Facet-Mediated Low Back Pain, Lumbar Facet Joint Osteoarthritis
Allogeneic BM-MSCs in Patients With Painful Lumbar Facet Arthropathy
The purpose of this research study is to evaluate the safety and effect of bone marrow-derived stem cells for the treatment of low back pain.
- Trial name
- CELLKINE II (NCT06001853)
- Testing
- BM-MSC injection, DSMO Injection
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Low Back Pain, Mechanical, Spinal Stenosis
Investigation of Hypermobility, Biomarkers, and Pain Generators in Chronic Pain Patients
Observational study of axial spine pain and hyperflexibility. Patients will receive physical exam maneuvers (traditional straight leg raise, FABER, facet loading as well as Beighton's hypermobility score) and blood / urine /…
- Conditions
- Low Back Pain, Mechanical, Spinal Stenosis, Nerve Root Disorder, Radiculopathy, Cervical
- Trial name
- Hypermoble (NCT02761928)
- Testing
- Beighton score for hypermobility
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- The University of Texas Health Science Center, Houston
Lumbar Facet Joint Pain
One-Needle Vs Three-Needle Radiofrequency in Low Back Pain Due to Facet Joint Arthritis
Failure of RFA has been attributed to technical failure of coagulating the nerve or coagulation of a minimal section of the nerve, allowing for early reinnervation.
- Trial name
- NCT05137652
- Testing
- Radiofrequency ablation of medial nerve using single needle approach, Radiofrequency ablation of medial nerve using three needle approach
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Chronic Low Back Pain
Genetic Predictors of Responsiveness to Radiofrequency Denervation in Chronic Low Back Pain
The Investigators have designed this exploratory study in patients suffering from zygapophysial joint mediated pain to investigate if a correlation exists between inter-individual genetic variability (genotype) with treatment…
- Trial name
- NCT02383524
- Testing
- Lumbar Radiofrequency Medial Branch Neurolysis
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Facet Joint Pain
A Multi-Site Study of the Zyga GlyDer Facet Restoration Device In Subjects With LUmbar FacET Pain Syndrome - DUET
A non-randomized, multi-site feasibility study to evaluate the safety of the Glyder Device in subjects with a history of lumbar facet joint disease (L2 to the sacrum) and successful neural ablation in which the facet joint is…
- Trial name
- DUET (NCT02179476)
- Testing
- Glyder
- Where
- 4 sites in United States
- Volunteers
- 2 people
- Sponsor
- Zyga Technology, Inc.
Facet Joint Pain
The Cervical Trident Study
This observational retrospective study evaluates the efficacy of RF with the three-tined expandable electrode needle compared to before treatment in the treatment of chronic cervical facet joint pain.
- Trial name
- NCT05353465
- Testing
- Radiofrequency denervation of the cervical facet joint
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Ospedale Regionale di Lugano
Lumbar Facet Joint Syndrome
The Role of Intra-articular Injection of PRP Versus Corticosteriods in Treatment of Lumbar Facet Disease
Low back pain is an extremely common health problem and recent studies have shown that nearly up to 52% of patients have low back pain caused by lumbar facet joint syndrome.
- Trial name
- PRP (NCT04860531)
- Testing
- Lumbar Facet Joints intra-articular injection with Platelet Rich Plasma, Lumbar Facet Joints intra-articular injection with a mixture of 0.5% lidocaine and 5mg/ml of betamethasone
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Neuralgia, Sciatic
An Effect and Safety Observation on PELD Technique for Extraforaminal Disc Herniation at L5/S1
43% or so of far lateral lumbar disc herniation (FLLDH) occurred at L5/S1, however, the surgical treatment is still quite challenging.
- Trial name
- NCT03511456
- Testing
- PELD operation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Low Back Pain, Mechanical, Facet Syndrome of Lumbar Spine
Comparative Evaluation of the Results of Facet Joint Injections
Low back pain affects 60 to 90% of the total population. It is one of the most common causes of disability in adults. Low back pain can be originated from a wide variety of structures, and the facet joint is one of these…
- Trial name
- NCT06325631
- Testing
- Intra-articular injection to lumbar facet joint
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Oznur Uzun
Facet Syndrome of Lumbar Spine
Double Arm Pivotal Study to Evaluate the Neurolyser XR for the Treatment of Chronic Low Back Pain
Double arm pivotal study to evaluate the Neurolyser XR as a non-invasive treatment of axial chronic low back pain
- Trial name
- NCT05154448
- Testing
- Non-Invasive Thermal Ablation of the Medial Branch Nerves (Neurolyser XR)
- Where
- 10 sites in United States
- Volunteers
- 90 people
- Sponsor
- FUSMobile Inc.
Cervical Facet Joint Pain
Treatment for Whiplash Injury
Objective: Cervical facet joint (CFJ) pain is commonly seen after whiplash injuries, and is frequently refractory to physical therapy and oral medication.
- Trial name
- NCT04959721
- Testing
- Injection with triamcinolone acetonide, bupivacaine, and normal saline
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Min Cheol Chang
Degenerative Disc Disease, Back Pain Lower Back Chronic
The SPINUS II Study: Spinal Fusion for Multilevel SPECT/CT Positive Lumbar Degeneration
The aim of the present study is to find out whether fusion of multilevel SPECT/CT positive lumbar degeneration leads to a significant improvement of pain and disability.
- Conditions
- Degenerative Disc Disease, Back Pain Lower Back Chronic, Facet Joint Arthropathy, Facet Syndrome of Lumbar Spine
- Trial name
- NCT04893720
- Testing
- Lumbar fusion
- Where
- 2 sites in Czechia
- Volunteers
- 30 people
- Sponsor
- Military University Hospital, Prague
Low Back Pain, Healthy
Analysis of Crepitus in Human Subjects
Chiropractic adjustment has been shown to gap certain joints in the spine, thereby improving mobility in individuals with decreased movement capabilities.
- Trial name
- CrUS (NCT05425017)
- Testing
- Range of motion with spinal adjustment
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National University of Health Sciences
Neck Pain
Radiofrequency Neurotomy for Chronic Facet Joint Related Neck Pain
This is a single-center, double blind, sham-controlled randomized trial (N: 34) to assess the long term efficacy of RF neurotomy of cervical medial branches.
- Trial name
- NCT03066960
- Testing
- Radiofrequency neurotomy
- Where
- 2 sites in Norway
- Volunteers
- 34 people
- Sponsor
- Oslo University Hospital
Cervicobrachial Neuralgia
Cervical Facet Injection of Corticosteroids for the Management of Cervicobrachialgia
The main objective is to evaluate the efficacy of a single posterior intra-articular injection of dexamethasone on radicular pain (RP) at 1 month in the treatment of uncomplicated chronic cervicobrachial neuralgia (CBN) in…
- Trial name
- APICALE (NCT07084285)
- Testing
- Dexamethasone, Isotonic saline solution
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Platelet-Rich Plasma
Platelet-Rich Plasma (PRP) for Treatment of Symptomatic Lumbar Facet Syndrome of the Spine
The purpose of this study is to investigate the feasibility of standardized autologous platelet rich plasma injections into osteoarthritic lumbar facet joints to treat back pain and improve patient function.
- Trial name
- NCT04522674
- Testing
- Autologous platelet rich plasma
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Colorado, Denver
Chronic Low-back Pain, Lumbar Facet Joint Syndrome
Ultrasound-guided LMBB by Caudal-cranial Approach: Radiographic Comparison of a New Ultrasound-guided Method
The current standard technique is radiography requiring three uni- or bilateral punctures (transverse-axial plane). The ultrasound technique is also described mainly in this plan but a new "caudal-cranial" ultrasound-guided…
- Trial name
- BLEPAC (NCT05930236)
- Testing
- Lumbar medial branch block, Lidocain, Methylprednisolone
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Erasme University Hospital