Clinical trials: Facial
Blepharoptosis, Lagophthalmos
Magnetic Correction of Eye Lid Paralysis
Objective 1: Determine the safety and feasibility of externally mounted magnets for extended management of chronic eyelid movement disorders by measuring visual acuity and corneal and skin integrity and comfort over 8 weeks of…
- Conditions
- Blepharoptosis, Lagophthalmos, Facial Paralysis
- Trial name
- NCT02988856
- Testing
- Magnetic lid system
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Kevin Houston
Orbital Fractures
The Use of 3D Printing in Orbital Fractures
The study is a prospective randomized longitudinal clinical study to compare pre-adapted patient-specific orbital implants utilizing an office-based 3-D printer versus standard non-adapted orbital implants (the latter being the…
- Trial name
- NCT03673865
- Testing
- office-based 3-dimensional printers (OB3DP), standard stock orbital plate
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Emory University
Eyebrow Lift, Improved Appearance of the Face and Neck
Effectiveness and Safety of the Octave System for Lifting the Eyebrow and Improving the Appearance of the Face and Neck
This study was conducted to evaluate the effectiveness and safety of the Octave System to lift the eyebrow and improve the appearance of the face and neck.
- Trial name
- LIFT-E (NCT05067504)
- Testing
- Octave-Ultherapy treatment
- Where
- 3 sites in United States, Puerto Rico
- Volunteers
- 50 people
- Sponsor
- Merz North America, Inc.
Dental Pain
Evaluation of the Efficacy and Safety of Diclofenac HPBCD 25, 50 mg/ml in the Treatment of Post-surgical Pain Following Dental Surgery
The present study is proposed to evaluate the efficacy and safety of single doses of Diclofenac HPBCD subcutaneous (s.c.) (25 mg/1 ml and 50 mg/1 ml) in the treatment of acute moderate-to-severe pain after dental impaction…
- Trial name
- NCT00942448
- Testing
- Diclofenac HPBCD
- Where
- 6 sites in Poland, United Kingdom
- Volunteers
- 306 people
- Sponsor
- IBSA Institut Biochimique SA
Actinic Keratoses
PRO With Luxerm® in the Field Treatment of Thin and Non-hyperkeratotic Non-pigmented AK
Interventional open label prospective and multicentre study conducted in Germany in subjects with thin or non-hyperkeratotic and non-pigmented multiple AKs in one anatomical area on the face (e.g., forehead or cheek or chin)…
- Trial name
- SESAME 2 (NCT03511326)
- Testing
- Methyl Aminolaevulinate 16% Cream
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Galderma R&D
Postoperative Nausea and Vomiting
Use of Baxter Animated Retching Faces (BARF) Scale to Measure Nausea in Children Who Speak Spanish
Pediatric research in the management of nausea has been limited by the absence of a reliable method to quantify the intensity of this subjective symptom.
- Trial name
- NCT02007109
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Aging
The Effectiveness of Epidermal Growth Factor Serum in Improve Facial Skin Hydration, Elasticity, Pigmentation, and Wrinkles.
EGF is a polypeptide that promotes cell differentiation and collagen production while decreasing melanin production. This study is designed to study its effectiveness in improving the texture and appearance of facial skin after…
- Trial name
- NCT05724589
- Testing
- Epidermal Growth Factor
- Where
- Thailand
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Institute of Dermatology, Thailand
Photoaging
Combination Versus Laser Treatment Only
Our objective is to determine the effects of (1) basic skin care regimen + "active" (Lytera 2.0) vs. (2) basic skin care regimen only, both groups combined with laser, on the appearance of skin tone and photo-aging on the face.
- Trial name
- NCT03661697
- Testing
- Laser Therapy, Basic Skin Care Regimen, Lytera
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Miami
Face Pain
Efficacy of Botulinum Toxin Versus Lidocaine in Treating Masticatory Myofascial Face Pain Using Ultrasound and EMG Guided Techniques
Botulinum toxin-A (BTX-A) prevents the release of acetylcholine in presynaptic terminals of the neuromuscular junction. It has been proposed to be effective in spastic conditions of the head and neck including oromandibular…
- Trial name
- NCT00992108
- Testing
- lidocaine, chemodenervation
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Influenza, Respiratory Syncytial Viruses
The Respiratory Protection Effectiveness Clinical Trial
Despite widespread use of respiratory protective equipment in the U.S. healthcare workplace, there is very little clinical evidence that respirators prevent healthcare personnel (HCP) from airborne infectious diseases.
- Conditions
- Influenza, Respiratory Syncytial Viruses, Paramyxoviridae Infections, Coronavirus
- Trial name
- ResPECT (NCT01249625)
- Testing
- N95 Respirator, Medical/surgical mask
- Where
- 7 sites in United States
- Volunteers
- 2,862 people
- Sponsor
- Johns Hopkins University
Acne Vulgaris
Efficacy and the Tolerability of the Sequential Application of Two Marketed Products in Patients With Acne Vulgaris
The aim of this proof of principle study is to evaluate efficacy and safety of the sequential application of two marketed products for the treatment of acne vulgaris, using the Split-Face model
- Trial name
- NCT01461655
- Testing
- marketed topical retinoid, marketed topical NSAID, vehicle gel
- Where
- France
- Volunteers
- 40 people
- Sponsor
- LEO Pharma
Skin Care
To Assess the Photosensitisation and Photoallergy Potential of a Cosmetic Facial Product in Healthy Participants
To evaluate the skin irritation and sensitization potential of a cosmetic facial product, under exaggerated conditions of use with controlled product application and under supervision of a dermatologist.
- Trial name
- NCT03183518
- Testing
- Facial micellar cleanser, Saline Solution: Sodium Chloride (NaCl; 0.9%)
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Typical Facial Pain, Atypical Facial Pain
Ultrasound Guided Trigeminal Nerve Block for Typical or Atypical Facial Pain
Trigeminal neuralgia is a craniofacial pain syndrome that is typically characterized by unilateral severe, recurrent, electrical pain in one or more distributions of the trigeminal nerve.
- Trial name
- NCT02024724
- Testing
- Bupivacaine, Triamcinolone, Dexamethasone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Northwestern University
Acne Vulgaris
Dapsone Gel 5% and Tazarotene Cream 0.1% Versus Tazarotene Cream 0.1% Monotherapy for Facial Acne Vulgaris
A 12-week evaluation of the safety and efficacy of dapsone gel 5% when used with tazarotene cream 0.1% compared with tazarotene cream 0.1% monotherapy in treating moderate to severe facial acne vulgaris
- Trial name
- NCT00834210
- Testing
- Dapsone, Tazarotene
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- Allergan
Upper Facial Lines (Glabellar Lines, Forehead Lines, & Lateral Canthal Lines)
Efficacy and Safety of DaxibotulinumtoxinA (DAXI) for Injection for Treatment of Upper Facial Lines
This is a Phase 2, multicenter, open-label, single-arm study to evaluate the efficacy and safety of DaxibotulinumtoxinA for injection (DAXI for injection) in the treatment of Glabellar Lines (GL), Dynamic Forehead Lines (FHL)…
- Trial name
- NCT04259086
- Testing
- DaxibotulinumtoxinA for injection
- Where
- 8 sites in United States, Canada
- Volunteers
- 48 people
- Sponsor
- Revance Therapeutics, Inc.
Aesthetic Dermatology
Safety and Effectiveness Clinical Evaluation of Injectable Medical Devices
The study aims to confirm the safety and effectiveness of FILLGEL devices
- Trial name
- NCT06142578
- Testing
- Dermal Filler Device
- Where
- Switzerland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Kylane Laboratoires
Acne Vulgaris
A Study to Evaluate the Clinical Effect of Daily Next Science™ Acne Gel (NAG) on Mild to Moderate Facial Acne
This is a 12 week, multi-site, double-blind, vehicle-controlled study in subjects with mild to moderate facial acne. Subjects will be randomized 1:1 to apply either topical NAG or vehicle gel daily.
- Trial name
- NCT02404285
- Testing
- Next Science Acne Gel, Vehicle
- Where
- 3 sites in United States
- Volunteers
- 68 people
- Sponsor
- Next Science TM
Dry Skin, Skin Care
To Evaluate the Effect of Moisturizing Creams on Skin Barrier Function
The aim of this study is to evaluate the impact of twice-daily topical application of two different moisturizing creams on skin barrier function for 4 weeks.
- Trial name
- NCT03804710
- Testing
- Developmental moisturizing cream 1, Developmental moisturizing cream 2, Standard cleanser soap
- Where
- Germany
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Smiling, Botulinum Toxins, Type A
Higher Doses of Botulinum Toxin in the Treatment of Gummy Smile
Botulinum type A (BTX-A) is an easy and efficacious treatment for gingival smile (GS). However, the necessary for higher-doses among patients are controversial.
- Trial name
- NCT05127018
- Testing
- injection of Botulinum type A
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Peking University
Laxity; Skin
Treatment With the Evoke System for Facial and Submental Laxity
The aim of the study is to evaluate the efficacy, patient comfort, and patient satisfaction after Evoke treatment for face and submental area
- Trial name
- NCT04719013
- Testing
- Evoke radiofrequency device
- Where
- 5 sites in United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- InMode MD Ltd.