Clinical trials: Facial Acne
Acne Vulgaris
Dapsone Gel 5% and Tazarotene Cream 0.1% Versus Tazarotene Cream 0.1% Monotherapy for Facial Acne Vulgaris
A 12-week evaluation of the safety and efficacy of dapsone gel 5% when used with tazarotene cream 0.1% compared with tazarotene cream 0.1% monotherapy in treating moderate to severe facial acne vulgaris
- Trial name
- NCT00834210
- Testing
- Dapsone, Tazarotene
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- Allergan
Acne Vulgaris
A Study to Evaluate the Safety and Efficacy of Tazarotene Foam, 0.1%, in Subjects With Common Facial Acne
The purpose of this study is to assess safety and efficacy of a new foam formulation of tazarotene in subjects with acne vulgaris.
- Trial name
- NCT01017120
- Testing
- Tazarotene Foam, Vehicle Foam
- Where
- 18 sites in United States, Canada
- Volunteers
- 742 people
- Sponsor
- Stiefel, a GSK Company
Acne Vulgaris
Evaluation of Irritation That Potentially Could be Caused by Two Facial Gels Applied to Opposite Sides of the Face
A study to compare the skin irritation potential of two marketed gels for acne treatment, each applied to half of the face of healthy volunteers.
- Trial name
- NCT00952523
- Testing
- Tretinoin Facial Gel, Adapalene/Benzoyl Peroxide Facial Gel
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Acne Vulgaris
Treatment of Moderate to Severe Facial Acne Vulgaris
Randomized, multi-center, double-blind, placebo-controlled 12-week study to assess the safety and efficacy of 3 doses of an oral formulation of Doxycycline oral tablets using the Investigator's Global Assessment (IGA) score and…
- Trial name
- NCT00612573
- Testing
- Doxycycline 0.6 mg/kg/day, Doxycycline 1.2 mg/kg/day, Doxycycline 2.4 mg/kg/day
- Where
- 23 sites in United States
- Volunteers
- 257 people
- Sponsor
- Warner Chilcott
Acne Scarring of the Face
Safety and Efficacy Study of Autologous Fibroblasts in the Treatment of Severe Facial Acne Scarring
The purpose of this study is to evaluate the safety profile and the treatment effect of Isolagen TherapyTM and placebo when administered to facial acne scars.
- Trial name
- NCT00642642
- Testing
- Autologous Human Fibroblasts (azficel-T)
- Where
- 7 sites in United States
- Volunteers
- 122 people
- Sponsor
- Castle Creek Biosciences, LLC.
Acne Vulgaris
A Phase 2 Study of ASC-J9 Cream in Acne Vulgaris
The purpose of this study is to evaluate if topical ASC-J9 cream is effective in treating acne.
- Trial name
- NCT00525499
- Testing
- ASC-J9 cream
- Where
- 10 sites in United States
- Volunteers
- 186 people
- Sponsor
- AndroScience Corp
Acne, Post Inflammatory Hyperpigmentation
LiftActiv B3 in Post Inflammatory Hyperpigmentation (PIHP)
The purpose of this research study is to measure the depigmenting effect of a serum product called Liftactiv B3 in patients with mild to moderate facial PIHP (Post Inflammatory Hyper Pigmentation)
- Trial name
- NCT05327361
- Testing
- Liftactiv B3, Sunscreen
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Miami
Acne Vulgaris
Light Dose Ranging Study of Photodynamic Therapy (PDT) With Levulan + Blue Light Versus Vehicle + Blue Light in Severe Facial Acne
The purpose of this study is to determine and compare the safety and efficacy of multiple broad area photodynamic therapy treatments with aminolevulinic acid (ALA-PDT) and vehicle (VEH-PDT) in subjects with moderate to severe…
- Trial name
- NCT00706433
- Testing
- aminolevulinic acid HCL (ALA), Vehicle (VEH)
- Where
- 14 sites in United States
- Volunteers
- 266 people
- Sponsor
- DUSA Pharmaceuticals, Inc.
Acne Scars - Mixed Atrophic and Hypertrophic, Acne
Pilot Study Investigating the Efficacy of Fat Grafting as a Treatment for Male and Female Facial Acne Scarring
This single-center, clinical trial consists of a one autologous fat grafting treatment followed by 3-month and 6-month post-treatment visits in order to assess the efficacy of fat grafting when used by men and women with facial…
- Trial name
- NCT04559022
- Testing
- Fat Grafting
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Acne Vulgaris
Comparison of Two Salicylic Acid Formulations
This study is a split face, paired-comparison, pilot study of at least 10 subjects to complete. Participants in this study will be patients seen at Children's Memorial Hospital, who are clinically diagnosed with mild to moderate…
- Trial name
- NCT00848744
- Testing
- Formulation A, Formulation B
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Atrophic Acne Scars
A Pilot Study to Evaluate the Safety and Effectiveness of Microneedling and Bellafill to Treat Facial Acne Scars
This is an open-label, randomized, multicenter, prospective trial assessing the efficacy and safety of microneedling treatment alone vs.
- Trial name
- NCT02643628
- Testing
- Microneedling, Microneedling followed by Bellafill treatment
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Suneva Medical, Inc.
Acne Vulgaris
Explorative Trial Evaluating the Efficacy and Tolerability of LEO43204 in Moderate to Severe Acne
An exploratory Phase 2, single, centre, prospective, randomized, placebo-controlled, double-blinded, split-pace (left/right) design trial to evaluate the efficacy and tolerability of LEO 43204 in adults with moderate to severe…
- Trial name
- NCT02575950
- Testing
- LEO43204
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- LEO Pharma
Acne Vulgaris
Double-Blind, Placebo-Controlled Study to Evaluate 3 Doses of a Novel Tetracycline in the Treatment of Facial Acne Vulgaris
To evaluate the safety and effectiveness of 3 strengths of P005672-HCl compared to placebo for the treatment of moderate to severe facial acne vulgaris.
- Trial name
- NCT01628549
- Testing
- 50 mg P005672-HCl, 100 mg P005672-HCl
- Where
- 38 sites in United States
- Volunteers
- 285 people
- Sponsor
- Almirall, S.A.
Acne Vulgaris
A Study That Evaluates the Decrease in Irritation When Using Additional Acne Treatment Products
This study is to see if there's any difference in the amount of facial irritation when two acne products are used together on one side of the face, compared to one acne treatment product used alone on the other side of the face.
- Trial name
- NCT01313728
- Testing
- Dapsone plus Tretinoin Gel, Tretinoin Gel
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Acne Vulgaris
8 Week Study to Evaluate and Compare the Efficacy and Tolerability of MAXCLARITY II and MURAD To Treat Acne
One of the main success factors in acne therapy is user compliance with treatment, product cost, availability and ease of use. Poor compliance may translate into decreased efficacy (either not improving symptoms well enough or…
- Trial name
- NCT02524665
- Testing
- MAXCLARITY II (2.5% BPO) Foam Cleanser, MAXCLARITY II (2.5% BPO) Foam Treatment, MAXCLARITY II (0.5% Salicylic Acid) Toner Foam
- Volunteers
- 20 people
- Sponsor
- Stiefel, a GSK Company
Acne Vulgaris
Photoactive Porphyrins (PAP) Levels After Topical Visonac Application in Acne Patients
Open, prospective, randomized, single-centre study in patients with moderate to severe facial acne vulgaris. Three circular areas with a diameter of 4 cm, each circle including at least 4 inflammatory lesions, will be selected in…
- Trial name
- NCT01160848
- Testing
- Area cleaned with saline water and occluded with Tegaderm, Area cleaned with saline water, Area cleaned with Ethyl alcohol solution
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Photocure
Acne Scars
The Smartlipo Triplex 1440nm Wavelength Laser and the Sidelaze 800 Hand Piece for the Treatment of Facial Acne Scars
The purpose of this study to evaluate the SmartLipo Triplex laser system along with the SideLaze800 hand piece in the treatment of Acne Scars.
- Trial name
- NCT02103816
- Testing
- SmartLipo Triplex laser system along with the SideLaze800 hand piece
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Cynosure, Inc.
Acne Vulgaris
CD5789 (Trifarotene) Long Term Safety Study on Acne Vulgaris
Multi-center, open-label, non-comparative safety and efficacy study with 52 Weeks of treatment on the face and trunk for acne vulgaris.
- Trial name
- NCT02189629
- Testing
- CD5789 (trifarotene)
- Where
- 32 sites in United States, Czechia and 2 more
- Volunteers
- 453 people
- Sponsor
- Galderma R&D
Acne Scars - Mixed Atrophic and Hypertrophic
Comparison of 1,550 and 755 Laser in a Split-face Trial
Clinical Trial comparing the 1,550-nanometer fractionated photothermolysis system laser to the 755 nanometer picosecond laser using a split-face (Right-Left) comparison.
- Trial name
- NCT03988049
- Testing
- 1,550 fracionated photothermolysis laser, 755 picosecond laser
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- David Smart
Acne Vulgaris
Split-face Tolerability Comparison Between Adapalene-Benzoyl Peroxide Gel Versus Tretinoin Gel
To compare the tolerability of Epiduo® (adapalene and benzoyl peroxide) Gel 0.1%/2.5% to Retin-A Micro® (tretinoin gel) microsphere when used by subjects with acne vulgaris for 3 weeks in terms of local tolerability parameters…
- Trial name
- NCT01522456
- Testing
- Epiduo Gel, Retin-A Micro Microsphere 0.1%
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Galderma R&D