Clinical trials: Facial Injuries and Disorders
Zygomatic Fractures
A Method of Calculating the Shortest Incision for Internal Fixation of Zygomatic Arch Fracture
In this study, a new method was proposed to calculate the length of sideburns mini incision for zygomatic arch fracture. The purpose of this study was to compare the sideburns mini incision calculated by this method with the…
- Trial name
- NCT05381337
- Testing
- sideburns mini incision, coronal scalp incision
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Wei Jing
Photophobia, Traumatic Brain Injury
Objectively Diagnose and Monitor Treatment of Light Sensitivity
The purpose of this project is to provide a new framework for diagnosing and monitoring treatment of light sensitivity and headache by objective measurement of facial features, pupil responses, retinal electrical responses and…
- Conditions
- Photophobia, Traumatic Brain Injury, Migraine
- Trial name
- NCT03694626
- Testing
- Pupillography, Ocular Coherence Tomography (OCT), Wrist-watch sensor device
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Randy Kardon
Trigeminal Nerve Injuries, Post-herpetic Neuralgia
Transcranial Magnetic Stimulation for Facial Pain
Complex oro-facial pain is a poorly diagnosed and poorly treated cause of significant suffering and disability. This study will explore the ability of fMRI to identify patients with complex oro-facial pain who respond to…
- Conditions
- Trigeminal Nerve Injuries, Post-herpetic Neuralgia, Facial Pain, Nervus Intermedius Neuralgia
- Trial name
- NCT02633306
- Testing
- transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Minnesota
Bone Loss, Jaw, Edentulous
Effectiveness of 3D-printed Patient-specific Resorbable Scaffolds for Maxillary Bone Regeneration
The objective of this study is to test the bone formation capacity of a 3D printed scaffold with a plastic material called Polycaprolactone (PCL), compared to the use of synthetic bone grafts, for bone formation in the maxilla or…
- Conditions
- Bone Loss, Jaw, Edentulous, Edentulous Mouth, Jaw Fractures
- Trial name
- OSTEOPRINT (NCT06773923)
- Testing
- PCL Scaffold, PTFE + Bio-Oss®
- Where
- Chile
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad Austral de Chile
Corneal Scar
Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Corneal Scars
This study will enroll subjects with recently formed corneal scars that resulted from a corneal insult presenting and diagnosed within the past approximately 30 days and not less than approximately 7 days.
- Trial name
- NCT06257355
- Testing
- CSB-001 Ophthalmic Solution 0.1%
- Where
- 7 sites in United States
- Volunteers
- 20 people
- Sponsor
- Claris Biotherapeutics, Inc.
Eye Burns
Low Dose Doxycycline in the Treatment of Corneal Burn
To evaluate the safety and efficacy of oral low dose doxycycline in the treatment of corneal burn.
- Trial name
- NCT01886560
- Testing
- Doxycycline
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Sun Yat-sen University
Corneal Injuries, Corneal Burns
Stem Cells Therapy for Corneal Blindness
This is a investigative initiated, comparative pilot clinical trial to ascertain the safety of application of ex-vivo cultivated limbal stem cells in human eyes for treating different superficial corneal pathologies.
- Conditions
- Corneal Injuries, Corneal Burns, Corneal Scars and Opacities
- Trial name
- ExCell (NCT02948023)
- Testing
- Ex-vivo cultivated limbal stem cell pool
- Where
- India
- Volunteers
- 100 people
- Sponsor
- L.V. Prasad Eye Institute
Mandibular Fractures, Facial Injuries
Aetiology and Pattern of 122 Patients With Mandibular Condylar Fracture
This retrospective observational study aimed to investigate the aetiology and fracture patterns among patients with mandibular condylar fractures (MCF) who were treated at a trauma center in Shiraz, Iran, between 2018 and 2020.
- Trial name
- NCT07099833
- Testing
- Azita Sadeghzade
- Where
- Iran
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Azita Sadeghzade
Orbital Fractures, Orbital Floor Fractures
A Trial to Evaluate Two Ectropion Preventive Measures Using the Subciliary Approach in Orbital Fracture Surgery.
The goal of this clinical trial is to investigate whether preventive surgical techniques can reduce the incidence of lower eyelid ectropion after the subciliary approach in adult patients undergoing surgery for orbital fractures.
- Trial name
- PREVENTECT (NCT07775417)
- Testing
- Subciliary Approach, Lateral Canthopexy, Orbicularis Oculi Suspension
- Volunteers
- 30 people
- Sponsor
- Minia University
Ocular Injury
Study of Retinal Vascular Changes After Ocular Blunt Trauma
This study evaluates the retinal vascular features using optical coherence tomography angiography in patients that received ocular blunt trauma.
- Trial name
- NCT04546997
- Testing
- Optical Coherence Tomography Angiography
- Where
- Italy
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Federico II University
Facial Nerve Injuries, Adenoma, Pleomorphic
Facial Nerve Morbidity After Superficial Parotidectomy in the Absence of Nerve Conductor
In this single-centre, cross-sectional case series, the investigators aim to evaluate the incidence of facial nerve injury in patients undergoing superficial parotidectomy in the absence of nerve conductor.
- Trial name
- NCT04706052
- Testing
- Superficial Parotidectomy
- Where
- Pakistan
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Liaquat University of Medical & Health Sciences
Craniocerebral Trauma, Facial Injuries
Financial and Clinical Impact of Repeal of the Pennsylvania Motorcycle Helmet Law
The purpose of this study is to find out how many helmeted versus non-helmeted motorcycle accident victims (MCA) sustain head and/or face injuries.
- Trial name
- NCT00200135
- Where
- 2 sites in United States
- Volunteers
- 480 people
- Sponsor
- Memorial Medical Center
Eye Trauma
Playtime Open Globe Injuries in Children
This study investigated the epidemiology, aetiologies, and complications of playtime open-globe injuries in children at the Assiut University Hospital, Egypt, between January to July 2016.
- Trial name
- NCT04497896
- Testing
- Repair of open globe injury
- Volunteers
- 81 people
- Sponsor
- Assiut University
Hemifacial Spasm
Effect on Tear Functions of Pretarsal and Preseptal Techniques of Botulinum Toxin Type A Injection in Hemifacial Spasm
The purpose of this study is to determine whether pretarsal and preseptal techniques of Botulinum toxin type A injection have any effect on tear functions.
- Trial name
- NCT01564979
- Testing
- preseptal injection of botulinum toxin type A, pretarsal injection of Botulinum toxin type A
- Where
- Thailand
- Volunteers
- 26 people
- Sponsor
- Khon Kaen University
Mandibular Reconstruction, Maxillofacial Injuries
Anatomical Research of the Clavicular Pedicled Flap for Mandibular Reconstruction
Because of the proximity of the clavicular bone to the oral cavity, and the suitable characteristics of the bone for implant placement, its use as a pedicled flap is an attractive method of mandibular reconstruction.
- Trial name
- NCT06255483
- Testing
- Osteoperiosteal pedicled clavicular flap for mandibular and facial bone reconstruction
- Where
- Tunisia
- Volunteers
- 10 people
- Sponsor
- Mohamed Tahar Maamouri University Hospital
Disorder of Consciousness, Consciousness, Loss of
SeeMe: An Automated Tool to Detect Early Recovery After Brain Injury
Early prediction of outcomes after acute brain injury (ABI) remains a major unsolved problem. Presently, physicians make predictions using clinical examination, traditional scoring systems, and statistical models.
- Conditions
- Disorder of Consciousness, Consciousness, Loss of, Trauma, Brain, Traumatic Brain Injury
- Trial name
- NCT06083441
- Testing
- SeeMe, Coma Recovery Scale-Revised (CRS-R)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Zygomaticomaxillary Complex Fracture, Zygoma Fracture
Accuracy of Positioning Guide and Customized Plate in Zygomaticomaxillary Complex Fractures
The goal of this clinical trial is to evaluate the accuracy and stability of positioning guides and customized titanium plates in the treatment of Zygomaticomaxillary Complex (ZMC) fractures.
- Conditions
- Zygomaticomaxillary Complex Fracture, Zygoma Fracture, Zygomatic Fractures
- Trial name
- NCT07608380
- Testing
- Patient-specific positioning guide, Customized titanium plate
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Cairo University
Corneal Disease, Corneal Opacity
Study to Evaluate the Clinical Safety and Performance of the CorNeat KPro for Treatment of Corneal Blindness
A Single Arm, Pivotal, Open Label, Multicenter Clinical Investigation to Evaluate the Clinical Safety and Performance of the CorNeat Keratoprosthesis, for Treatment of Corneal Blindness
- Conditions
- Corneal Disease, Corneal Opacity, Corneal Injuries
- Trial name
- NCT05694247
- Testing
- CorNeat KPro
- Where
- 6 sites in Canada, France and 2 more
- Volunteers
- 15 people
- Sponsor
- CorNeat Vision Ltd.
Corneal Abrasion, Eye Trauma
Bandage Contact Lenses for Corneal Abrasions
Two percent of all patients presenting to the Emergency Departments have complaints involving the eye. Corneal abrasions are a common diagnosis with patients with eye pain and often cause significant discomfort.
- Trial name
- NCT03206723
- Testing
- Bandage contact lens, Eyedrop, Hydrocodone
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Facial Asymmetry, Mandible; Hypoplasia, Unilateral Condylar
Accuracy of a CAD/CAM Surgical Template for Mandible Distraction
The purpose was to assess the accuracy and clinical validation of virtual planning and surgical template in mandible distraction osteogenesis. Patients with hemifacial microsomia were enrolled.
- Conditions
- Facial Asymmetry, Mandible; Hypoplasia, Unilateral Condylar, Distraction of Bone
- Trial name
- NCT03270618
- Testing
- CAD/CAM Surgical Template
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University