Clinical trials: Facial Neoplasms
Skin Cancer Face, Surgical Incision
Exploratory Prospective of Experienced by Patients in the Surgery of Skin Cancers of the Face in Interventional Dermatology Department
Surgery is the first-line treatment of localized skin cancers. Knowledge on the patient's psychological experience is limited. Therefore, the psychological impact on patients before, during and after surgery can be…
- Trial name
- VECUCHIR (NCT04336371)
- Testing
- Self-administered questionnaires
- Where
- France
- Volunteers
- 98 people
- Sponsor
- University Hospital, Bordeaux
Actinic Keratosis
A Multi-Center Study to Evaluate the Efficacy and Safety of KX01 Ointment 1% on Actinic Keratosis on Face or Scalp
This Phase III study is designed to evaluate the efficacy and safety of KX01 Ointment in adult participants when applied to an area of skin containing more than 1, clinically typical Actinic Keratosis (AK) lesions on the face or…
- Trial name
- NCT05231044
- Testing
- KX01 ointment 1%
- Where
- 20 sites in Japan
- Volunteers
- 108 people
- Sponsor
- PharmaEssentia
Parotid Tumors, Facial Nerve Paresis
Intra-parotid Facial Nerve Imaging in Parotidectomy
In this study, the investigators will evaluate the clinical usefulness of 3 dimensional double echo steady state MRI (3D-DESS MRI) for functional preservation of the facial nerve during parotidectomy.
- Trial name
- NCT03822728
- Testing
- 3D-DESS MRI (3 dimensional double echo steady state MRI)
- Where
- South Korea
- Volunteers
- 270 people
- Sponsor
- Samsung Medical Center
Head and Neck Cancers
Biomedical Innovation for Facial Bone Reconstruction in Oncology: BIOFACE PASS a Medico-economic Study Describing the Standard Pathway of Patients Treated by Free Bone Flap
The purpose of this study is to describe the standard of care pathway of patients treated by free bone flap for facial mandibullar or maxillar reconstruction after surgery for head and neck cancers.
- Trial name
- BIOFACE PASS (NCT06771336)
- Testing
- Questionnaires
- Where
- 9 sites in France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Toulouse
Chronic Pain, Cancer Pain
Refining mUltiple Artificial intelliGence strateGies for Automatic Pain Assessment Investigations: RUGGI Study
This single-center, non-profit, observational-interventional study aims to develop artificial intelligence (AI) models for the automatic assessment of chronic pain (APA - Automatic Pain Assessment).
- Conditions
- Chronic Pain, Cancer Pain, Neuropathic Pain, Pain Assessment
- Trial name
- RUGGI (NCT07038434)
- Testing
- Multimodal AI-Based Pain Assessment
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Valentina Cerrone
Facial Nerve Injuries, Adenoma, Pleomorphic
Facial Nerve Morbidity After Superficial Parotidectomy in the Absence of Nerve Conductor
In this single-centre, cross-sectional case series, the investigators aim to evaluate the incidence of facial nerve injury in patients undergoing superficial parotidectomy in the absence of nerve conductor.
- Trial name
- NCT04706052
- Testing
- Superficial Parotidectomy
- Where
- Pakistan
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Liaquat University of Medical & Health Sciences
Hemangioma
The Effectiveness of Diode Laser 980-nm in Iraqi Face Hemangioma: a Randomized Within Patients Trial
In an academic, government clinic, uni-center, randomized within patients trial study of the effects of 980-nm diode laser treatment included 15 cases of facial hemangiomas in patients with a history of discomfort due to lesions…
- Trial name
- NTDL980 (NCT04065217)
- Testing
- Diode laser 980-nm
- Where
- Iraq
- Volunteers
- 15 people
- Sponsor
- Noor Taha Ismaeel
Trigeminal Neuralgia, Secondary
3D-CT-guided Percutaneous Radiofrequency Thermocoagulation for Tumor-related Trigeminal Neuralgia
This study is designed to investigate the effectiveness and safety of 3D-CT-guided percutaneous radiofrequency thermocoagulation for the treatment of tumor-related trigeminal neuralgia.
- Trial name
- NCT03549013
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Beijing Tiantan Hospital
Distress, Anxiety
(Cost-)Effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) in Cancer Patients
Mindfulness-based cognitive therapy has been demonstrated to be effective in reducing anxiety, depression and fatigue in cancer patients. As this intervention can be offered in groups, costs are relatively low.
- Conditions
- Distress, Anxiety, Depression
- Trial name
- BeMind (NCT02138513)
- Testing
- Mindfulness Based Cognitive Therapy
- Where
- 2 sites in Netherlands
- Volunteers
- 245 people
- Sponsor
- Radboud University Medical Center
Photosensitivity Disorders
Comparison of the Efficacy and Tolerability of Solaraze for 3 Versus 6 Months in Patients With Mild to Moderate Actinic Keratosis Located on the Face and Head
Topical treatment of mild to moderate actinic keratosis located on the face and head with Solaraze® is known to be a safe and efficient treatment option.
- Trial name
- NCT00204542
- Testing
- Diclofenac
- Where
- 4 sites in Germany
- Volunteers
- 418 people
- Sponsor
- University Hospital Tuebingen
Nevus, Seborrheic Keratosis (SK)
Impact of Skin Type on Wonud Healing and Scarring Following Facial Skin Surgery
The goal of this observational study is to learn how an individual's skin type influences the wound healing process and scar formation in Chinese patients undergoing facial dermatologic surgery.
- Conditions
- Nevus, Seborrheic Keratosis (SK), Cyst, Lipoma
- Trial name
- NCT07384299
- Where
- China
- Volunteers
- 173 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Skin Cancer Face, Quality of Life
Buddy Relationships in DermatoloGic Excisions for Skin Cancer
More than 5 million skin cancer surgeries are performed each year in the United States with 80% of tumors appearing on the head and neck.
- Conditions
- Skin Cancer Face, Quality of Life, Surgical Wound, Peer Mentorship
- Trial name
- BRIDGES (NCT04036344)
- Testing
- Peer Mentorship Program
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Physical Fitness, Health
Effects of the Face Mask on Physical Fitness in Children
The aim of this multicenter randomized crossover design study is to evaluate a sample of 500 boys and girls from public and private schools in the Principality of Asturias, aged between 6 and 12 years, with the objective of…
- Conditions
- Physical Fitness, Health, Childhood ALL, Emotional Stress
- Trial name
- MaskFIT (NCT04800848)
- Testing
- Mask
- Where
- Spain
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of Oviedo
Parotid Neoplasms
Application of 3D MR Neurogram for Intraparotid Facial Nerves Evaluation
Parotid neoplasm consists of a wide range of benign and malignant lesions, and parotidectomy has been the mainstay for management of these neoplasms.
- Trial name
- NCT05296109
- Testing
- Magnetic Resonance Imaging on 3T scanner (Magnetom Prisma, SIemens) with dedicated neurogram sequences (Constructive interference in steady state - CISS; Dual Echo Steady State - DESS)
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Actinic Keratosis, Imipramine
The Effect of Topical Imipramine on Photodynamic Therapy-Mediated Immunosuppression on Forearms or Face on US Veterans
The purpose of this study is to test the use of topical imipramine in combination with topical photodynamic therapy's (PDT) effect on the effectiveness and pain immunosuppression following treatment.
- Conditions
- Actinic Keratosis, Imipramine, Photodynamic Therapy
- Trial name
- NCT06778434
- Testing
- Imipramine, Control Vehicle
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- VA Office of Research and Development
Cancer Cervix
Vaginal Self-sampling and Human Papillomavirus Testing in Unscreened Women
Despite the existence of an effective screening test (pap smear), cervical cancer is, every year in France, the cause of more than 3,000 new cases and 1,100 deaths.
- Trial name
- APACHE-3 (NCT02255084)
- Testing
- Group 1 remove self sample kit at gp consulting room or perform pap smear, Group 2 perform self sample at home or pap smear
- Where
- France
- Volunteers
- 3,612 people
- Sponsor
- University Hospital, Tours
Cutaneous Squamous Cell Carcinoma
Evaluating the Use of Photodynamic Therapy to Treat Facial Cutaneous Squamous Cell Carcinoma in Situ (SCCis)
The goal of this clinical trial is to test how safe and effective it is to treat early form of cancer cells found in the upper skin layer of the face, using a light-sensitive gel used in combination with a light source.
- Trial name
- NCT06577311
- Testing
- Aminolevulinic acid hydrochloride 10% topical gel with Red Light
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The Center for Clinical and Cosmetic Research
Prostate Cancer
Study to Evaluate a New Method to Detect Residual Tumours During Surgery for Prostate Cancer Using Confocal Microscopy
Prostate cancer is the most common solid cancer affecting male patients worldwide. When diagnosed early, it can usually be cured with surgery (radical prostatectomy), but this procedure is associated with side effects such as…
- Trial name
- NCT06398470
- Testing
- NeuroSAFE procedure, LaserSAFE procedure
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- University College, London
Actinic Keratosis
Metvix PDT Versus Vehicle PDT With Aktilite CL128 Lamp in Patients With Actinic Keratosis on the Face and Scalp
The purpose of this study was to compare the efficacy of Photodynamic Therapy (PDT) with methyl aminolevulinate (MAL) cream to PDT with vehicle cream, using the Light-emitting diode (LED) light source Aktilite CL128, in treatment…
- Trial name
- NCT00304239
- Testing
- Metvix-PDT, Vehicle-PDT
- Where
- 11 sites in United States, Germany
- Volunteers
- 131 people
- Sponsor
- Galderma R&D
Actinic Keratoses
Evaluation of The Efficacy and Safety of Tixel Treatment for the Treatment of Facial and/or Scalp Actinic Keratoses
Evaluation of the Efficacy and Safety of a thermal fractional skin treatment system (Tixel) for the treatment of facial and/or scalp actinic keratoses
- Trial name
- NCT04527653
- Testing
- Tixel
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Novoxel Ltd.