Clinical trials: Facial Neoplasms
Actinic Keratoses
Treatment of Actinic Keratoses (AK) on the Face
Actinic keratoses (AK) are common cutaneous lesions associate with chronic ultraviolet radiation exposure. While most authorities consider AK as a pre-malignant lesion, some consider it as an incipient squamous cell carcinoma…
- Trial name
- NCT02411851
- Testing
- ingenol mebutate 0.015%, dermasil lotion
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Parotid Tumor
Role of Methylene Blue in Parotid Surgery
usefulness of the methylene blue staining for identification of facial nerve in parotid gland surgery
- Trial name
- NCT05401370
- Testing
- Methylene blue dye
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
Actinic Keratosis
Efficacy of AFL-assisted PDT With Short Incubation Time in Actinic Keratosis
Photodynamic therapy (PDT) using methyl aminolevulinate (MAL) is an effective first-line treatment for actinic keratosis (AK). Erbium: yttrium-aluminium-garnet (Er:YAG) ablative fractional laser-assisted MAL-PDT (AFL-PDT) has…
- Trial name
- NCT02248298
- Testing
- 2h-AFL-PDT, 3h-AFL-PDT, 3hr-MAL-PDT
- Where
- South Korea
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Dong-A University
Skin Cancer, Basal Cell, Skin Cancer
A Comparison of Skin Grafts Versus Local Flaps for Facial Skin Cancer From the Patient Perspective: A Feasibility Study
A prospective single-centered feasibility study will be conducted. The purpose of the feasibility study is to define the variables to be included in a subsequent pilot study, assess the feasibility of conducting a prospective…
- Conditions
- Skin Cancer, Basal Cell, Skin Cancer, Skin Cancer, Non-Melanoma, Skin Cancers - Squamous Cell Carcinoma
- Trial name
- NCT04805905
- Testing
- FACE-Q patient reported outcome
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McMaster University
Actinic Keratoses
Topical Imiquimod Cream in Combination With Cryotherapy for the Treatment of Actinic Keratoses
The purpose of this study is to determine if use of topical imiquimod cream after cryotherapy of actinic keratoses reduces the total number of lesions (those treated with cryotherapy and new ones) at follow-up.
- Trial name
- NCT00774787
- Testing
- imiquimod 5% cream
- Where
- 3 sites in United States
- Volunteers
- 27 people
- Sponsor
- Rigel Dermatology
Angiofibroma of Face, Tuberous Sclerosis
Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex
The objective of this study is to evaluate the safety and efficacy of sirolimus (0.2% and 0.4% formulations) and its vehicle when applied topically once daily for 12 weeks for the treatment of cutaneous angiofibromas in pediatric…
- Trial name
- NCT03363763
- Testing
- Sirolimus 0.2%, Sirolimus 0.4%
- Where
- 8 sites in United States, China
- Volunteers
- 24 people
- Sponsor
- Aucta Pharmaceuticals, Inc
Actinic Keratosis
A Simultaneous Treatment Regimen Compared to a Sequential Treatment Regimen With Ingenol Mebutate Gel 0.015% and 0.05% of Two Areas With Actinic Keratosis on Face/Scalp and Trunk/Extremities
The purpose of this trial is to evaluate the safety of a simultaneous treatment regimen compared to a sequential treatment regimen when two separate areas with AKs (one located on face/scalp and the other located on trunk/…
- Trial name
- NCT01787383
- Testing
- Ingenol mebutate gel 0.05 %, Ingenol mebutate gel 0.015 %
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- LEO Pharma
Breast Neoplasm
Factor Influencing Breast Surgery Type Decision-Making
The aim of this observational study is to determine the factors influencing the decision-making process for breast surgery type, in Lebanese women likely to face breast cancer.
- Trial name
- NCT05604677
- Testing
- Breast Surgery
- Where
- Lebanon
- Volunteers
- 380 people
- Sponsor
- Etienne El Helou
Neoplastic Syndrome
Topical Tazarotene in Treating Patients With Basal Cell Skin Cancer and Basal Cell Nevus Syndrome on the Face
RATIONALE: Drugs used in chemotherapy, such as tazarotene, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00489086
- Testing
- tazarotene
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Keratosis, Actinic
A Study to Evaluate the Safety and Tolerability of Tirbanibulin Ointment 1% in Adult Participants With Actinic Keratosis
The purpose of the study is to evaluate the safety, tolerability and treatment effect of tirbanibulin ointment 1% when applied to a field of approximately 100 cm^2 on the face or balding scalp.
- Trial name
- NCT05279131
- Testing
- Tirbanibulin ointment 1%
- Where
- 7 sites in United States
- Volunteers
- 105 people
- Sponsor
- Almirall, S.A.
Actinic Keratoses
Cryotherapy in Combination With Red Light PDT for Actinic Keratosis of Full Face
40 patients randomized 1:1 to receive cryotherapy followed by 10% ALA gel Red light PDT vs. to 10% ALA gel Red Light PDT followed by cryotherapy.
- Trial name
- NCT06745999
- Testing
- Ameluz 10% Topical Gel, Red Light PDT, Cryotherapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Psoriasis Treatment Center of Central New Jersey
Metastatic Solid Tumor, Locally Advanced Solid Tumor
Topical Tretinoin Prophylaxis for Anti-EGFR Induced Skin Toxicity in Patients With Solid Tumors
The goal of this clinical trial is to learn if using topical tretinoin will help patients with solid tumors who are experiencing an acneiform rash as a side effect of their treatment.
- Trial name
- FACE (NCT06358677)
- Testing
- Topical Tretinoin
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Utah
Surgery, Cancer of Skin
Computer Modelling to Plan Surgical Reconstruction
The aim of this study is to improve patient satisfaction and outcomes in facial reconstructive surgery by using 3D clinical photography and computer modelling to help illustrate and plan the patients' reconstructive journey.
- Trial name
- NCT04968704
- Testing
- 3D photography and computer modelling
- Volunteers
- 10 people
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Facial Neoplasms, Head and Neck Neoplasms
Clinical Trial of New Elastomer for Maxillofacial Prosthetics
The purpose of this study is to evaluate a new rubber material used to make prosthetic replacements of the face lost to cancer, trauma, or birth defects.
- Conditions
- Facial Neoplasms, Head and Neck Neoplasms, Head Injuries, Penetrating, Birth Injuries
- Trial name
- NCT00123097
- Testing
- Chlorinated polyethylene elastomer
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Louisville
Mandibular Neoplasms, Maxillary Neoplasms
Three-Dimensional Printing of Patient-Specific Titanium Plates in Jaw Surgery: A Pilot Study
Medical titanium plates are routinely used in fixing mobilized bone segments in jaw surgeries. Generally these plates are commercialized with standard construction specifications.
- Conditions
- Mandibular Neoplasms, Maxillary Neoplasms, Dentofacial Deformities, Maxillofacial Injuries
- Trial name
- 3DJP16 (NCT03057223)
- Testing
- 3D-printed patient-specific titanium plates
- Where
- Hong Kong
- Volunteers
- 96 people
- Sponsor
- The University of Hong Kong
Being Literate, Not Having Any Cognitive, Visual or Orthopedic Disabilities
The Effect of Face-to-Face and Online Training on Cancer Screening on Women's Knowledge, Attıtude and Shyness
Cancer is a large group of diseases that occur due to abnormal cell proliferation in almost all organs of the body. Cancer is the second leading cause of death in the world after cardiovascular diseases.
- Conditions
- Being Literate, Not Having Any Cognitive, Visual or Orthopedic Disabilities, Being Between the Ages of 50-65, Having a Smart Phone
- Trial name
- NCT06979960
- Testing
- cancer screening education
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Inonu University
Skin Cancer, Cutaneous Tumor
Alpha Radiation Emitters Device (DaRT) for the Treatment of of Malignant Cutaneous Tumors
A unique approach for cancer treatment employing intratumoral diffusing alpha radiation emitter device for Malignant Cutaneous Tumors
- Conditions
- Skin Cancer, Cutaneous Tumor, Cutaneous Metastasis
- Trial name
- NCT04068155
- Testing
- DaRT- Diffusing Alpha-emitters Radiation Therapy
- Where
- 2 sites in France
- Volunteers
- 80 people
- Sponsor
- Alpha Tau Medical LTD.
Eyelid Tumor
Mohs Surgery Combind With Cryotherapy for Eyelid Malignant Tumors.
This study aim to investigate whether the prognosis of eyelid malignant tumor is better treated with Mohs surgery combind with cryotherapy than Mohs surgery only.
- Trial name
- NCT05072327
- Testing
- Mohs surgery, cryotherapy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Sun Yat-sen University
Thyroid Nodule
Verbal Synchrony, Satisfaction and Decision-making in Face-to-face Consultations
Eligible participants will be: benign thyroid nodules patients, to be involved in a consultation with their endocrinologist and/or surgeon and/or radiologist, in order to discuss treatment options related to benign thyroid…
- Trial name
- NCT06342739
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- European Institute of Oncology
Parotid Gland Tumor, Facial and Neck Rhytides
Facial Nerve Monitoring During Parotid and Facial Surgery Using a Non-Invasive Patch
The goal of this study is to test if a non-invasive patch can safely monitor facial nerve activity in adults during parotid or facial surgery.
- Trial name
- NCT07523373
- Testing
- Non-invasive facial nerve monitoring patch
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center