Clinical trials: Facial Nerve Injuries
Pain Management
Local Anesthesia for Facial Fractures
The study is a double-blind randomized, placebo controlled trial examining the impact of perioperative bupivacaine nerve block on PACU recovery metrics.
- Trial name
- LAFF (NCT06429501)
- Testing
- Bupivacaine/Epinephrine, Saline
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Washington University School of Medicine
CNLDO - Congenital Nasolacrimal Duct Obstruction, Amblyopia
Improving the Follow up Rate for Pediatric Patients
Follow-up of pediatric patients is important for their regular ocular morbidity monitoring, especially for amblyopia management.
- Conditions
- CNLDO - Congenital Nasolacrimal Duct Obstruction, Amblyopia, Conjunctivitis, Eye Injuries
- Trial name
- NCT04837534
- Testing
- Counseling group, SMS and phone call reminder group
- Where
- Nepal
- Volunteers
- 264 people
- Sponsor
- Seva Foundation
Non-arteritic Anterior Ischemic Optic Neuropathy (NAION), Trauma
Electric Stimulation of the Eye to Improve Vision After Trauma
Transcorneal Electrical Stimulation (TES) using the "OkuStim®" device delivers electrical impulses to damaged and/or diseased photoreceptor cells.
- Conditions
- Non-arteritic Anterior Ischemic Optic Neuropathy (NAION), Trauma, Multiple Sclerosis (MS)
- Trial name
- TES (NCT02019927)
- Testing
- Transcorneal Electrical Stimulation
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Wills Eye
Inferior Alveolar Nerve Injuries
Orthodontic Extrusion of High Risk Impacted Mandibular Third Molar
The goal of this clinical trial is to investigate the usage of maxillary miniscrew and cross-arch elastics for the orthodontic traction of the impacted mandibular third molar in close proximity to the inferior alveolar nerve to…
- Trial name
- NCT06538688
- Testing
- Orthodontic extrusion of the impacted mandibular third molar by using the maxillary miniscrew and cross arch elastic power chain as a temporary anchorage device before extraction
- Where
- 3 sites in Egypt
- Volunteers
- 9 people
- Sponsor
- Alexandria University
Orofacial Pain, Trigeminal Neuralgia
An Follow-up Study of Occlusal Adjustment for Orofacial Pain
The purpose of this study is to determine whether what kind of occlusion are related the orofacial pain under investigation, and whether occlusal adjustment have an effect in relief of this kind of orofacial pain.
- Trial name
- NCT02856906
- Testing
- occlusal adjustment
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Meiqing Wang
Hemifacial Paralysis, Bell Palsy
Electrical Stimulation to Improve Recovery After Peripheral Nerve Injury
After nerve injury and facial palsy, many patients have permanent muscle and sensory dysfunction. Electrical stimulation (ES) of injured nerves may speed up axon growth and improve recovery.
- Trial name
- NCT03996525
- Testing
- Electrical Stimulation
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- The Hospital for Sick Children
Nerve Injury, Laser Therapy
Histopathological, Biochemical And Electrophysiological Evaluation Of Single Or Combined Use Of Diode Laser/Steroid Treatment On Facial Nerve Injury
The objective of the study will be to investigate the effect of low-level diode laser therapy (LLLT) and steroid on facial nerve injury.
- Conditions
- Nerve Injury, Laser Therapy, Methylprednisolone, Facial Nerve Injuries
- Trial name
- facial nerve (NCT06185426)
- Testing
- Methyprednisolon and low level laser theraphy
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Postoperative Infections, Mandibular Nerve Injuries
Surgeons' Prediction of Dental Surgery Complications and the Influence of Patient Characteristics: Development of an AI Model
The goal of this observational study is to learn how to better predict and prevent intra- and postoperative complications in oral surgery in adult patients referred for oral surgical procedures.
- Conditions
- Postoperative Infections, Mandibular Nerve Injuries, Alveolar Osteitis, Complication
- Trial name
- NCT07461324
- Where
- 2 sites in Denmark
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Orbital Fractures, Strabismus
Factors Associated With Postoperative Strabismus After Floor Fracture Repair
In patients suffered from floor fractures, there are 21.9% complaining about diplopia before fracture repair surgery and 20.8% after operation. Even after 6 months, there still are 16.4% had similar conditions.
- Trial name
- NCT02736461
- Testing
- Floor repair surgery
- Where
- Taiwan
- Volunteers
- 110 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Inferior Alveolar Nerve Injuries
Risk of Nerve Damage After Administration of Local Anesthesia
This research aims to evaluate of the risk of nerve damage following the administration of articaine 4% and lidocaine 2% for Inferior Alveolar nerve Block (IANB).
- Trial name
- NCT06564987
- Testing
- 4% Articaine with 1:200,000 epinephrine, 2% lidocaine with 1:100,000 epinephrine
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cleveland Dental Institute
Cochlear Hearing Loss, Hearing Loss, Sensorineural
Minimizing Facial Nerve Stimulation in Cochlear Implants
This study aims to understand how to manipulate the electrical stimulation from the cochlear implant to maximize hearing stimulation and minimize facial stimulation.
- Conditions
- Cochlear Hearing Loss, Hearing Loss, Sensorineural, Hearing Loss, Facial Nerve Injury
- Trial name
- NCT04161261
- Testing
- Electrical Stimulation
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Impacted Third Molar Tooth, Tooth Extraction Status Nos
Clinical Validation of a Novel Classification for Predicting Surgical Complexity in Mandibular Wisdom Teeth Surgery
The study evaluates and validates a new classification proposed by Juodzbalys and Daugela in 2013 predicting the complexity of impacted mandibular third molars surgical extraction, comparing it with other two, scientifically…
- Trial name
- NCT02519426
- Testing
- Mandibular third molar surgery
- Where
- 2 sites in Italy, Lithuania
- Volunteers
- 110 people
- Sponsor
- Lithuanian University of Health Sciences
Facial Nerve Injuries, Facial Paresis Associated With Facial Nerve Dysfunction
Comparison of Three Botulinum Neuromodulators for Management of Facial Synkinesis
The purpose of this study is to compare the effectiveness of three commercially available botulinum toxin neuromodulators in the treatment of facial synkinesis using patient reported outcome measures.
- Conditions
- Facial Nerve Injuries, Facial Paresis Associated With Facial Nerve Dysfunction, Facial Asymmetry, Synkinesis
- Trial name
- NCT03048383
- Testing
- OnabotulinumtoxinA Injectable Product, AbobotulinumtoxinA Injectable Product, Incobotulinumtoxin A Injectable Product
- Volunteers
- 71 people
- Sponsor
- University of Utah
Peripheral Nerve Facial Nerve Paralysis, Facial Nerve Diseases
Study of a New Technique to Improve the Symptoms of Orofacial Discomfort in Patients With Peripheral Facial Paralysis
The purpose of this study was to evaluate the effects of Neuro Occlusal Rehabilitation (RNO) in patients with peripheral facial palsy (PFP) disease, noting the decrease in symptoms of masticatory dysfunction.
- Conditions
- Peripheral Nerve Facial Nerve Paralysis, Facial Nerve Diseases, Orofacial Pain
- Trial name
- NCT01327157
- Testing
- occlusal adjustment., Visual analog scale.
- Where
- Brazil
- Volunteers
- 14 people
- Sponsor
- Federal University of São Paulo
Inferior Alveolar Nerve Injuries, Impacted Third Molar Tooth
The Impact of 3D-CBCT Imaging on Nerve Injuries During Wisdom Tooth Surgery
The investigators aim to investigate if the additional information available from a 3D scan of the wisdom tooth can reduce the risk of nerve injury during wisdom tooth surgery compared to conventional 2D images.
- Trial name
- IMPACTION (NCT06261853)
- Testing
- 3D-CBCT, 2D-OPG
- Where
- 2 sites in United Kingdom
- Volunteers
- 1,292 people
- Sponsor
- University of Aberdeen
Surgery, Brain Tumor
Neurosurgical Transitional Care Programme
Readmissions increasingly serve as a metric of hospital performance, inviting quality improvement initiatives in both medicine and surgery.
- Conditions
- Surgery, Brain Tumor, Brain Tumor, Recurrent, Brain Pathology
- Trial name
- TCP (NCT03593330)
- Testing
- Transitional Care Programme
- Where
- United Kingdom
- Volunteers
- 242 people
- Sponsor
- Barts & The London NHS Trust
Nerve Injury, Orofacial Pain
Post-traumatic Neuropathy of the Trigeminal Nerve
This is retrospective research mainly aims to determine the patterns of symptoms, clinical and radiological findings and outcomes in patients with trigeminal neuropathy following trauma or iatrogenic damage and how this…
- Conditions
- Nerve Injury, Orofacial Pain, Trigeminal Nerve Injuries, Trigeminal Neuropathy
- Trial name
- NCT04612855
- Testing
- Groupwise comparison of primary and secondary outcomes
- Where
- Belgium
- Volunteers
- 1,333 people
- Sponsor
- KU Leuven
Inferior Alveolar Nerve Injuries
Does Low-level Laser Therapy Protocol Affect the Efficacy of Treatment of Inferior Alveolar Nerve Injury After Maxillofacial Surgery
Dear Patient, Dear Parent / Guardian; This consent form has been prepared to enlighten you about the nature of the diagnosis and treatment methods that have been explained to you/patient and will be applied, the expected benefits…
- Trial name
- NCT06893497
- Testing
- Low Level Laser Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Karadeniz Technical University
Facial Nerve Injuries, Facial Trauma
Neurorrhaphy Only vs Neurorrhaphy Plus PRF vs Neurorrhaphy Plus Nano-fat in Management of Traumatic Facial Nerve Injury
The current clinical trial aims to identify the most significant intervention that improves the outcome of post-traumatic facial nerve injury by comparing the following different modalities: neurorrhaphy alone, neurorrhaphy with…
- Trial name
- facialinjury (NCT06977607)
- Testing
- Platelets Rich Fibrin, Nano-fat stem cells (NFSCs), Repair only
- Where
- Egypt
- Volunteers
- 21 people
- Sponsor
- Assiut University