Clinical trials: Facial Rhytides
Facial Photoaging, Deepening of Facial Wrinkles
Regenmedic Cream 2.0 12-week Long-term Clinical Test
The goal of this study is to evaluate the anti-wrinkle, firming, moisturizing and repairing efficacy of a test facial cream after single use and 12 weeks of continuous use via clinical evaluation, instrumental measurement, image…
- Conditions
- Facial Photoaging, Deepening of Facial Wrinkles, Skin Laxity, Decreased Skin Elasticity
- Trial name
- NCT07874113
- Testing
- Test facial cream (topical skin care product)
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Skin Wrinkling
Emervel® Deep Lidocaine vs. Juvederm® Ultra Plus in Treatment of Moderate to Severe Facial Wrinkles and Folds
The purpose of the study was to compare the effectiveness and safety of Emervel Deep Lidocaine versus Juvederm Ultra Plus in the treatment of moderate to severe facial wrinkles and folds.
- Trial name
- NCT01205061
- Testing
- Emervel Deep Lidocaine, Juvederm Ultra Plus
- Where
- 11 sites in United States
- Volunteers
- 162 people
- Sponsor
- Galderma R&D
Facial Rhytides, Crow's Feet Lines
Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Crow's Feet Lines and Frown Lines
This study will evaluate the safety and efficacy of botulinum toxin Type A compared to placebo for the treatment of Crow's Feet Lines and Frown Lines (Facial Rhytides)
- Conditions
- Facial Rhytides, Crow's Feet Lines, Glabellar Lines
- Trial name
- NCT01189760
- Testing
- onabotulinumtoxinA 24 U, onabotulinumtoxinA 44 U, normal saline
- Where
- 4 sites in United States, Canada and 2 more
- Volunteers
- 917 people
- Sponsor
- Allergan
Laxity; Skin
Efficacy of Micro-excisional Skin Removal by Micro-coring Device in Treatment of Wrinkles and Laxity of Face and Neck
This is a prospective, multi-center, pilot study evaluating effectiveness of micro-excisional skin remodeling by micro-coring skin in subjects meeting the Inclusion Criteria.
- Trial name
- MCD (NCT03583918)
- Testing
- HighThroughput Micro Coring Device
- Where
- 5 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cytrellis Biosystems, Inc.
Upper Facial Lines
A Study to Evaluate Participant Satisfaction and Natural Outcomes Following Administration of BOTOX Cosmetic Injections in Adult Participants for Treatment of Upper Facial Lines
Facial lines that develop from repeated facial expression, such as glabellar lines (GL), lateral canthal lines (LCL), and forehead lines (FHL), are typically treated by selectively weakening specific muscles with small quantities…
- Trial name
- UFL BOND 974 (NCT06218251)
- Testing
- BOTOX
- Where
- 10 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- AbbVie
Wrinkle
BTL-785F Device for Non-invasive Facial Rejuvenation in Patients Injected With Botulinum Toxin
This study will evaluate the clinical safety and the efficacy of the BTL-785F system equipped with the BTL-785-7 applicator for non-invasive facial treatment in patients injected with botulinum toxin.
- Trial name
- NCT05524766
- Testing
- BTL-785-7 Treatment
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Rhytids, Skin Laxity
Safety and Efficacy of 2910 nm Fiber Laser Resurfacing and Laser-Coring
The primary objective of this clinical trial is to evaluate the safety and effectiveness of the 2,910 nm mid-infrared erbium-doped fluoride fiber glass laser (UltraClear, Acclaro Medical) for non-invasive dermatological aesthetic…
- Trial name
- NCT07254884
- Testing
- 2,910 nm mid-infrared erbium-doped fluoride fiber glass laser (UltraClear, Acclaro Medical)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- FA Corporation
Skin Aging
Pilot Study to Evaluate the Safety and the Efficacy of the Matrix and Cells Obtained by the AmeaCell® Device and Intended for the Filling of Wrinkles on the Face.
The purpose of this study is to evaluate the filling using the Matrix and Cells, obtained by the Ameacell® device from autologous adipose tissue and intended for the filling of wrinkles on the face.
- Trial name
- SKINMAT (NCT03529292)
- Testing
- AmeaCell
- Where
- Belgium
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Symbioken
Hyaluronic Acid, Dermal Fillers
Clinical Trial of Cross-linked Hyaluronic Acid Dermal Filler
The goal of this clinical trial is to evaluate the safety and efficacy of Formaderm Young Dermal Filler Injection, which is a hyaluronic acid dermal filler injected into the mid to deep dermis for the correction of…
- Trial name
- NCT05935501
- Testing
- Formaderm Young, Restylane
- Where
- 2 sites in China
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Maxigen Biotech Inc.
Appearance of Facial Wrinkles
Safety and Efficacy of Single Therapy Versus Double and Triple Therapy of the Pellevé™ Wrinkle Treatment System for the Treatment of Moderate Facial Wrinkles
The study will enroll and treat a patients to assess improvement in the appearance of facial wrinkles.
- Trial name
- NCT01299103
- Testing
- Pelleve Wrinkle Treatment System
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ellman International
Facial Wrinkles and Rhytides Reduction
Cream Short-term Efficacy Clinical Study
This study aimed to evaluate the short-term efficacy of a facial cream (Formula# 899675 44A) on improving various skin quality and wrinkle parameters after a single application.
- Trial name
- NCT07067086
- Testing
- Test Cream
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Wrinkles
Study of BOTOX and JUVEDERM for Treatment of Moderate to Severe Facial Wrinkles and Folds
The purpose of this study is to see how well Juvederm Ultra XC or Juvederm Ultra Plus XC, and BOTOX Cosmetic, work compared to each other and when used together for the cosmetic treatment of age-associated wrinkles and folds of…
- Trial name
- JUVE_BTX (NCT01269801)
- Testing
- onabotulinumtoxinA, JUVÉDERM
- Where
- 3 sites in United States, Canada
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- AboutSkin Dermatology and DermSurgery, PC
Wrinkle
BTL-785F Device for Non-invasive Reduction of Wrinkles and Overall Facial Improvement
This study will evaluate the clinical safety and the performance of the BTL-785F system equipped with the BTL-785-7 applicator for non-invasive treatment of facial wrinkles.
- Trial name
- NCT05524779
- Testing
- BTL-785-7
- Where
- 5 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Lateral Canthal Lines
Safety and Efficacy Study of RT001 to Treat Moderate to Severe Lateral Canthal Lines
The purpose of this study is to determine the safety and efficacy of 2 sequential doses of RT001 compared to vehicle control following applications at Baseline (Day 0) and Week 2.
- Trial name
- NCT00884234
- Testing
- Vehicle Control, RT001 (Botulinum Toxin Type A Topical Gel)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Revance Therapeutics, Inc.
Wrinkle
Clinical and Histological Evaluation of BTL-785F Non-invasive Treatment for Facial Rejuvenation
This study will evaluate the clinical efficacy, safety and the performance of the BTL-785-2 applicator of the BTL-785F system for non-invasive treatment of facial wrinkles and correcting facial skin laxity.
- Trial name
- NCT05987917
- Testing
- BTL-785-2, No Treatment
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Facial Wrinkles, Skin Aging
Anti-Wrinkle Efficacy of a Syringic Acid-Containing Emulsion
This randomized, double-blind, split-face controlled study was conducted to evaluate the anti-wrinkle efficacy and safety of a Syringic acid-containing emulsion in healthy female subjects.
- Trial name
- NCT07850817
- Testing
- Synox-containing Emulsion, Control Emulsion
- Where
- South Korea
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- BioSpectrum Inc
Wrinkle Severity Rating Scale(WSRS) Grade 3 (Moderate) or 4 (Severe) of Nasolabial Folds
Clinical Trial of YYD701-2 for Treatment of Nasolabial Folds
A multicenter, active-controlled, randomized, evaluator and subject blinded, split-face, comparative, non-inferiority, Medical device Clinical trial.
- Trial name
- NCT03170050
- Testing
- YYD701-2, Restylane Perlane Lidocaine
- Where
- 2 sites in South Korea
- Volunteers
- 107 people
- Sponsor
- Yooyoung Pharmaceutical Co., Ltd.
Facial Wrinkles, Anti-Aging
Safety and Efficacy Evaluation of the Monopolar Radiofrequency Device for the Improvement of Facial Wrinkles
The goal of this clinical trial is to evaluate the safety and efficacy of the monopolar radiofrequency therapy device developed by CLASSYS Inc. for improving facial and periorbital wrinkles.
- Conditions
- Facial Wrinkles, Anti-Aging, Wrinkles and Rhytides, Wrinkles Such as Nasolabial Folds
- Trial name
- NCT06657365
- Testing
- Radiofrequency (RF) Treatment with Volnewmer, Radiofrequency (RF) Treatment with Thermage CPT
- Where
- China
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- CLASSYS Inc.
Facial Wrinkles, Rhytides
The Use of J-Plasma® for Dermal Resurfacing
This study evaluates the safety and effectiveness of J-Plasma in the reduction of facial wrinkles and rhytides. It is a multi-center, single arm, evaluator-blind prospective study of 55 study subjects who are seeking a procedure…
- Trial name
- NCT03286283
- Testing
- J-Plasma
- Where
- 3 sites in United States
- Volunteers
- 55 people
- Sponsor
- Apyx Medical
Visible Skin Aging Signs, Wrinkles and Folds in Lower Face
Efficacy of a Combined Oral and Topical Collagen Regimen Compared to Topical Collagen or Oral Collagen Regimens in Women With Skin Ageing Signs
This clinical study is conducted at one study site and in 165 women with visible signs of skin aging. It compares after 13 weeks the benefit of a combined oral collagen supplement and topical collagen serum regimen compared with…
- Conditions
- Visible Skin Aging Signs, Wrinkles and Folds in Lower Face, Skin Ageing, Skin Elasticity
- Trial name
- NCT07473037
- Testing
- Oral collagen, topical application of collagen serum
- Volunteers
- 165 people
- Sponsor
- Vichy Laboratoires