Clinical trials: Facial Skin Condition
Acne Vulgaris
Study for Long-term Treatment of Acne Vulgaris With Skinoren Versus Differin
The purpose of this study is to assess the effect of Skinoren® 15% gel compared to no therapy on the maintenance of clinical therapy success in subjects with mild to moderate acne vulgaris previously treated for 3 months by a…
- Trial name
- SKADI (NCT01387048)
- Testing
- skinoren, differin
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Magdeburg
Actinic Keratosis
Metvix PDT Versus Vehicle PDT With Aktilite CL128 Lamp in Patients With Actinic Keratosis on the Face and Scalp
The purpose of this study was to compare the efficacy of Photodynamic Therapy (PDT) with methyl aminolevulinate (MAL) cream to PDT with vehicle cream, using the Light-emitting diode (LED) light source Aktilite CL128, in treatment…
- Trial name
- NCT00304239
- Testing
- Metvix-PDT, Vehicle-PDT
- Where
- 11 sites in United States, Germany
- Volunteers
- 131 people
- Sponsor
- Galderma R&D
Wrinkle, Skin Laxity
A 28-day Clinical Study on Facial Skin Rejuvenation
This clinical trial aims to learn about the efficacy of MLYAAT-1002® (a proprietary anti-aging complex, MLYAAT is short for "multi-layer anti-ageing technology" ) in female subjects who have newly received the rejuvenation…
- Conditions
- Wrinkle, Skin Laxity, Skin Manifestations, Skin
- Trial name
- NCT06140628
- Testing
- Fotona4D Pro® treatment followed by daily use of formulations containing MLYAAT-1002®, Fotona4D Pro® treatment followed by daily use of formulations without MLYAAT-1002®
- Where
- China
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Botanee Group Co., Ltd.
Facial Skin Condition
BeauSaki Bird's Nest Peptide Efficacy
The goal of this clinical trial is to learn whether BeauSaki Edible Bird's Nest Peptide Product can improve facial skin conditions in healthy adult participants.
- Trial name
- NCT07723508
- Testing
- BeauSaki Edible Bird's Nest Peptide Product
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chia Nan University of Pharmacy ＆ Science
Laxity; Skin
Treatment With the Evoke System for Facial and Submental Laxity
The aim of the study is to evaluate the efficacy, patient comfort, and patient satisfaction after Evoke treatment for face and submental area
- Trial name
- NCT04719013
- Testing
- Evoke radiofrequency device
- Where
- 5 sites in United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- InMode MD Ltd.
Junctional Epidermolysis Bullosa, Epidermolysis Bullosa (EB)
Pilot Study of ELK-003 Eye Drops for Treating Ocular Manifestations of Epidermolysis Bullosa
This study consists of two phases: an Observational Phase to evaluate the natural history of ocular manifestations in subjects with Dystrophic and Junctional Epidermolysis Bullosa, followed by a Treatment Phase to assess the…
- Conditions
- Junctional Epidermolysis Bullosa, Epidermolysis Bullosa (EB), Dystrophic Epidermolysis Bullosa, Recessive Dystrophic Epidermolysis Bullosa
- Trial name
- GOTAS-ELK-EB (NCT06713434)
- Testing
- ELK-003 (Standarized Amniotic Fluid Secretome Eye Drops)
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- Fundación DEBRA Chile, Niños Piel de Cristal
Acne Vulgaris
Split-face Tolerability Comparison Between Adapalene-Benzoyl Peroxide Gel Versus Tretinoin Gel
To compare the tolerability of Epiduo® (adapalene and benzoyl peroxide) Gel 0.1%/2.5% to Retin-A Micro® (tretinoin gel) microsphere when used by subjects with acne vulgaris for 3 weeks in terms of local tolerability parameters…
- Trial name
- NCT01522456
- Testing
- Epiduo Gel, Retin-A Micro Microsphere 0.1%
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Galderma R&D
Melasma
Comparative Efficacy of Resveratrol 1 % Gel and Trichloroacetic Acid 20% in Treatment of Melasma: A Split-face Study
1. To evaluate the efficacy and safety of topical resveratrol 1 % gel in treatment of melasma. 2. To compare between the efficacy of topical resveratrol 1 %gel versrs chemical peeling with TCA 20% in melasma.
- Trial name
- NCT07060157
- Testing
- resveratrol 1 % gel, TCA20%
- Where
- Egypt
- Volunteers
- 41 people
- Sponsor
- Assiut University
Skin Laxity, Wrinkle
Clinical Study to Evaluate the Efficacy and Safety of Matrix Pro Treatment
This is a non-randomized, multi-center, open-label, prospective clinical trial evaluating clinical treatments with the Matrix Pro Applicator for the improvement of facial and/or submental and neck laxity.
- Conditions
- Skin Laxity, Wrinkle, Skin Condition
- Trial name
- NCT06726122
- Testing
- Profound Matrix
- Where
- 3 sites in Netherlands, United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Freckles
Efficacy and Safety of Fractional Carbon Dioxide Laser for Treatment of Facial Freckles.
Freckles are clusters of melanin in the superficial epidermis. They affect mostly face and sun exposed areas, and appear as flat brown or red macules that fade in winter, usually in a fair complexion patient, but may be present…
- Trial name
- NCT01545869
- Testing
- Fractional carbon dioxide laser
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Keratosis, Actinic
A Study of Tirbanibulin Ointment and Diclofenac Sodium Gel for the Treatment of Adult Participants With Actinic Keratosis on the Face or Scalp
The purpose of the study is to evaluate the incidence of biopsy confirmed invasive squamous cell carcinoma (SCC) in the selected treatment field (TF) after administration of topical tirbanibulin 10 milligram (mg)/gram (g)…
- Trial name
- AKtive (NCT05387525)
- Testing
- Tirbanibulin (Klisyri®) 10 mg/g ointment, Diclofenac Sodium 3% Gel
- Where
- 49 sites in France, Germany and 4 more
- Volunteers
- 447 people
- Sponsor
- Almirall, S.A.
Cushing's Syndrome
A Study of the Efficacy and Safety of CORLUX in the Treatment of Endogenous Cushing's Syndrome
Patients will receive Corlux (mifepristone) daily for up to 24 weeks. Assessments of the signs and symptoms of Cushing's syndrome will be obtained.
- Trial name
- SEISMIC (NCT00569582)
- Testing
- mifepristone
- Where
- 17 sites in United States
- Volunteers
- 50 people
- Sponsor
- Corcept Therapeutics
Melasma
Different Dermatological Approaches the Treatment of Melasma
To compare the efficacy and safety of cryopeeling (using Liquid Nitrogen) and tranexemic acid (cyclokapron) versus chemical peeling (using TCA 20%) in treatment of melasma.
- Trial name
- NCT03923062
- Testing
- chemicalpeeling, cryopeeling, microneedling
- Volunteers
- 40 people
- Sponsor
- Assiut University
Basal Cell Carcinoma
Basal Cell Carcinoma Chemoprevention Trial
This is an intent-to-treat, parallel design, multicenter randomized trial and the primary intervention is a double-blind comparison of imiquimod (IMQ) vs.
- Trial name
- B3C (NCT05212246)
- Testing
- 5% Imiquimod cream
- Where
- 8 sites in United States
- Volunteers
- 1,630 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Acne Scars
Evaluation of Juläine (TM) for the Treatment of Atrophic Facial Acne Scars
This study aims to evaluate the effectiveness and safety of Juläine, an injectable medical device made of polylactic acid, for treating facial acne scars.
- Trial name
- NCT07058883
- Testing
- Juläine
- Where
- 2 sites in Poland
- Volunteers
- 55 people
- Sponsor
- Nordberg Medical AB
Psoriasis, Cardiovascular Diseases
Prevalence and Risk Factors asSOciated With CArdiac comorbiDIty in psoriAsis
In a prospective cohort study (n = 1.000), the investigators aim to investigate the correlation between cardiac biomarkers and advanced echocardiography and determine whether these are prognostic markers of heart disease in…
- Conditions
- Psoriasis, Cardiovascular Diseases, Cardiovascular Risk Factor, Cardiovascular Pathology
- Trial name
- PSOCADIA (NCT04950218)
- Where
- Denmark
- Volunteers
- 1,000 people
- Sponsor
- Herlev and Gentofte Hospital
Acne Vulgaris on the Face
Safety and Efficacy of Topical AT-004 1% in Participants With Acne Vulgaris (AV)
Double blinded, randomized, placebo-controlled trial to determine the safety and efficacy of topical AT-004 therapy in participants with acne vulgaris, including assessment of reduction in the number of acne lesions and IGA.
- Trial name
- NCT07774364
- Testing
- AT-004
- Where
- 3 sites in Denmark
- Volunteers
- 63 people
- Sponsor
- Arctic Therapeutics
Face, Skin Fold
Efficacy of Prabotulinum and Onabotulinum Toxin-A for Facial Wrinkles
The appearance of facial wrinkles, lines, or folds is a natural phenomenon during aging. Different scales help classify wrinkles objectively, such as the Facial Wrinkle Scale.
- Conditions
- Face, Skin Fold, Rejuvenation
- Trial name
- NCT05840445
- Testing
- Onabotulinum toxin A, Prabotulinumtoxin A
- Where
- 2 sites in Mexico
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Rosacea
4 Week In-Use Study Evaluating How Well-Tolerated a Skin Care Product Is on Adults With Facial Redness
The purpose of this study is to evaluate if the test sunscreen skin care product will be well-tolerated and help facial redness when applied to the face after 4 weeks.
- Trial name
- NCT03841032
- Testing
- Coppertone, BAY1183345
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Bayer
X Linked Hypohidrotic Ectodermal Dysplasia
Phenotypic Properties in Individuals Affected With XLHED
The current study design incorporates two previously developed, non-invasive approaches to characterize the phenotype of individuals affected with XLHED.
- Trial name
- ECP-014 (NCT01871714)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Edimer Pharmaceuticals