Clinical trials: Facial Skin Condition
Rosacea
Randomized, Double-blind, Multiple-site, Placebo-controlled, Parallel-design Study in Patients With Moderate to Severe Facial Erythema Associated With Rosacea
A Randomized, Double-Blind, Multiple-Site, Placebo-Controlled, Parallel-Design Study to Evaluate the Safety and Therapeutic Equivalence of Brimonidine Topical Gel, 0.33% (Watson Laboratories, Inc., USA) to Reference Product…
- Trial name
- NCT02289352
- Testing
- Brimonidine
- Where
- 16 sites in United States
- Volunteers
- 462 people
- Sponsor
- Actavis Inc.
Acne Vulgaris, Acne
Skin Hydration in Persons With Acne After Dietary Supplementation With Botanical Antioxidants
Antioxidants have been studied for their abilities to combat reactive oxygen species in a multitude of conditions. This study aims to assess whether the botanical dietary supplement 'Halo Beauty Kiwi Booster' (HBKB), taken orally…
- Trial name
- KIWIBOOSTER (NCT04534140)
- Testing
- HBKB Capsule, HBKB Supplement Vehicle
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Melasma (Facial Melasma)
Efficacy and Safety of Triple-Combination Cream Plus Microneedling Along With Tranexamic Acid Versus Platelet-Rich Plasma in the Treatment of Moderate-to-Severe Melasma: A Randomized Comparative Study
Background Melasma is a chronic acquired pigmentary disorder characterized by symmetrical hyperpigmented macules and patches, predominantly affecting the face.
- Trial name
- NCT07893067
- Testing
- Group B (Triple Combination Cream + Microneedling + Platelet-Rich Plasma)
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- Bangladesh Medical University
Skin Laxity, Facial Aging
RESTRUCTURING THE MANDIBULAR ANGLE IN FACIAL AGING: A NOVEL TECNIQUE USING POLY-L-LACTIC ACID
Skin laxity is a common complaint among patients seeking aesthetic dermatological interventions, affecting the facial contour, especially in the mandibular angle, due to bone aging and the loss of tissue support in the lower…
- Trial name
- NCT06948045
- Testing
- PLLA application to the mandibular angle
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Doris Hexsel
ACTINIC KERATOSIS
An Equivalence Study of Generic Ingenol Mebutate Gel 0.015% and Picato Gel 0.015% in Subjects With Actinic Keratosis
The objective of this study was to evaluate the safety and therapeutic equivalence of generic ingenol mebutate gel, 0.015% to Picato gel, 0.015% by establishing the therapeutic comparability of the two active products and the…
- Trial name
- NCT03200912
- Testing
- Ingenol Mebutate (Picato®), Generic Ingenol Mebutate, Vehicle Foam
- Where
- 23 sites in United States
- Volunteers
- 507 people
- Sponsor
- Actavis Inc.
Actinic Keratosis
Microneedle Lesion Preparation Prior to Aminolevulinic Acid Photodynamic Therapy (ALA-PDT) for AK on Face
The purpose of this study is to determine the viability of microneedle lesion preparation (MN) to enhance treatment benefit when performed prior to ALA PDT to an actinic keratosis (AK) field on the face.
- Trial name
- NCT02632110
- Testing
- ALA, Topical Solution Vehicle, IBL 10 mW
- Where
- 8 sites in United States
- Volunteers
- 137 people
- Sponsor
- DUSA Pharmaceuticals, Inc.
Melasma
Melanil in the Treatment of Melasma
The purpose of the study is to assess the efficacy of Melanil facial cream in the treatment of melasma. The duration of this double-blind phase 3 clinical trial will be 54 weeks.
- Trial name
- NCT01001624
- Testing
- Melanil facial cream, Hydroquinone 2% cream
- Where
- Cuba
- Volunteers
- 150 people
- Sponsor
- Catalysis SL
Lentigines, Post Inflammatory Hyperpigmentation
Topical Corticosteroids on the Incidence of Postinflammatory Hyperpigmentation After QsNdYAG Laser
To investigate the benefit of the application of topical high potency steroid on the incidence of post inflammatory hyperpigmentation after laser treatment.
- Trial name
- NCT02492373
- Testing
- topical 0.05% Clobetasol propionate ointment, Q switched Nd:YAG laser 532 nm
- Where
- Thailand
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Atrophy
Postmenopausal Facial Skin After Estradiol and Genistein Topical Treatment
The aim of this trial was to compare the effects of estradiol or genistein treatment on the hialuronic acid concentration on the postmenopausal facial skin.
- Trial name
- NCT01553773
- Testing
- isoflavone, Estradiol
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of São Paulo
Rosacea
CGB-400 for the Reduction of Facial Redness
Open-label multicenter study using CGB-400 Gel (cosmetic) to reduce facial redness
- Trial name
- NCT04508660
- Testing
- CGB-400
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- CAGE Bio Inc.
Acne
Pilot Study to Evaluate Tea Tree Oil Gel for Facial Acne
Mild to moderate facial acne is an extremely common disease of teenagers and young adults. This pilot study will investigate whether treatment with a gel containing tea tree oil reduces numbers of acne lesions and improves acne…
- Trial name
- NCT01657110
- Testing
- Tea tree oil
- Where
- 2 sites in Australia
- Volunteers
- 18 people
- Sponsor
- The University of Western Australia
Melasma
EFFICACY and TOLERABILITY of TESTED FORMULA VS. HYDROQUINONE 4% in the TREATMENT of FACIAL MELASMA
This study aims at assessing the non-inferiority of tested formula facial serum (2039125 03) versus hydroquinone 4% over 3 months for treatment and then 3 months for maintenance ofwomen subjects presenting facial melasma.
- Trial name
- NCT06787846
- Testing
- Experimental: Group TP, Active Comparator: Group HQ: Hydroquinone 4%
- Where
- Brazil
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Rosacea
To Evaluate the Therapeutic Equivalence and Safety in Treatment of Moderate Facial Rosacea
To demonstrate the superiority of the efficacy of the test and reference products over that of the placebo control in the treatment of moderate facial rosacea.
- Trial name
- NCT03689010
- Testing
- Azelaic acid foam 15%, Finacea® (Azelaic acid Foam) 15%, Vehicle of the test product
- Where
- United States
- Volunteers
- 1,116 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Acne Vulgaris
Evaluation of Efficacy and Tolerance of Crystal Peel in the Treatment of Adults Presenting Facial Mild Acne
The goal of this interventional, confirmatory and post market study is to evaluate the efficacy and clinical performance of Crystal Peel in adults suffering mild facial acne vulgaris.
- Trial name
- NCT05821296
- Testing
- Crystal Peel
- Where
- Poland
- Volunteers
- 42 people
- Sponsor
- Dermosciences France
Psoriasis
A Study to Investigate Efficacy and Safety of VTAMA® (Tapinarof) Cream, 1% in Plaque Psoriasis in the Head and Neck Region
This is an open-label, multi-center study to evaluate the efficacy and safety of VTAMA (tapinarof) cream, 1% in adults with plaque psoriasis occurring in the head and neck region
- Trial name
- NCT05789576
- Testing
- VTAMA (tapinarof) cream, 1%
- Where
- 10 sites in United States
- Volunteers
- 31 people
- Sponsor
- Organon and Co
Acne Vulgaris
U0289-401: Eight Week, Split-face, Study to Determine and Compare the Efficacy and Tolerability of MAXCLARITY™ II to PROACTIV™
One of the main success factors in acne therapy is user compliance with treatment, product cost, availability and ease of use. Poor compliance may translate into decreased efficacy (either not improving symptoms well enough or…
- Trial name
- NCT01706250
- Testing
- MAXCLARITY II (2.5% BPO) Foam Cleanser, MAXCLARITY II (2.5% BPO) Foam Treatment, MAXCLARITY II (0.5% Salicylic Acid) Toner Foam
- Volunteers
- 20 people
- Sponsor
- Stiefel, a GSK Company
Laxity; Skin
Efficacy of Micro-excisional Skin Removal by Micro-coring Device in Treatment of Wrinkles and Laxity of Face and Neck
This is a prospective, multi-center, pilot study evaluating effectiveness of micro-excisional skin remodeling by micro-coring skin in subjects meeting the Inclusion Criteria.
- Trial name
- MCD (NCT03583918)
- Testing
- HighThroughput Micro Coring Device
- Where
- 5 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cytrellis Biosystems, Inc.
Actinic Keratosis
Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Face or Chest Including 12-month Follow-up
The objective of the trial is to compare the short term efficacy of LEO 43204 gel with vehicle gel in AK on face or chest when applied topically once daily for 3 consecutive days as field treatment.
- Trial name
- NCT02547233
- Testing
- LEO 43204 gel, Vehicle gel
- Where
- United States
- Volunteers
- 437 people
- Sponsor
- LEO Pharma
Acne Vulgaris
Efficacy and Tolerance of a Derivative of Salicylic Acid and 5% Benzoyl Peroxide in Facial Acne Vulgaris
Acne vulgaris is a frequent inflammatory skin condition involving the pilosebaceous unit and affecting more than 80% of teenagers.
- Trial name
- NCT00624676
- Testing
- Lipo Hydroxy Acid, 5% benzoyl peroxide gel
- Where
- 2 sites in Canada
- Volunteers
- 80 people
- Sponsor
- Cosmetique Active International
Acne Vulgaris
A Phase 2 Dose Escalating Study to Evaluate the Safety and Efficacy of CB-03-01 Cream in Subjects With Facial Acne Vulgaris
CB-03-01 is being developed for the topical treatment of acne vulgaris, an androgen-dependent skin disorder. The purpose of this study is to compare the safety and efficacy of multiple concentrations of CB-03-01 to vehicle in the…
- Trial name
- NCT01631474
- Testing
- CB-03-01, Vehicle
- Where
- 13 sites in United States
- Volunteers
- 363 people
- Sponsor
- Intrepid Therapeutics, Inc.