Clinical trials: Facial Skin Condition
Acne Vulgaris
BLI1100 for the Treatment of Moderate to Severe Acne Vulgaris
The purpose of this study is to compare the safety and efficacy of formulation BLI1100 to its vehicle in the treatment of moderate-severe acne vulgaris.
- Trial name
- NCT01241331
- Testing
- BLI1100, Vehicle cream
- Where
- 20 sites in United States
- Volunteers
- 233 people
- Sponsor
- Braintree Laboratories
Vitiligo
Safety and Efficacy of ARQ-252 Cream 0.3% in Subjects With Non-Segmental Facial Vitiligo
This study will assess the safety and efficacy of ARQ-252 cream in combination with NB-UVB phototherapy treatment in individuals with non-segmental facial vitiligo.
- Trial name
- NCT04811131
- Testing
- ARQ-252 cream 0.3%, ARQ-252 Vehicle cream, NB-UVB phototherapy active treatment
- Where
- 5 sites in United States
- Volunteers
- 114 people
- Sponsor
- Arcutis Biotherapeutics, Inc.
Rosacea
To Evaluate the Therapeutic Equivalence and Safety of Azelaic Acid 15% Topical Gel
A Multi-Center, Double-Blind, Randomized, Placebo Controlled, Parallel-Group Study
- Trial name
- NCT03094403
- Testing
- Azelaic Acid 15% topical gel, Finacea® (azelaic acid) Gel, 15%
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Eyelid Tumor, Xanthelasma Palpebrarum
Efficacy and Safety of Ultrapulse Carbon Dioxide Laser Treatment in Eyelid Tumors
This study aims to assess the long-term efficacy and safety of ultrapulse carbon dioxide (CO₂) laser excision in the treatment of eyelid tumors, including xanthelasma, pigmented nevi, keratoses, and so on.
- Conditions
- Eyelid Tumor, Xanthelasma Palpebrarum, Pigmented Nevi, Keratosis
- Trial name
- NCT06206681
- Testing
- Ultra-pulsed Carbon Dioxide Laser
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Sun Yat-sen University
Scar, Surgical Wound
Correlation of Early Postoperative Scar Appearance With Long-term Scar Outcomes
A retrospective cohort study of early and late period postoperative scars using previously validated survey measures and clinical photographs.
- Conditions
- Scar, Surgical Wound, Quality of Life, Mohs Micrographic Surgery
- Trial name
- NCT04015453
- Testing
- Mohs micrographic surgery
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Acne Vulgaris
Silymarin Cream Versus Salicylic Acid in Treatment of Acne Vulgaris
Acne vulgaris is a disease of the pilosebaceous unit that causes noninflammatory lesions (open and closed comedones), inflammatory lesions (papules, pustules, and nodules), and varying degrees of scarring.
- Trial name
- NCT04490967
- Testing
- Silymarin, Salicylic acid
- Volunteers
- 30 people
- Sponsor
- Assiut University
HIV Infection, Antiretroviral Side Effects
Polyacrylamide Hydrogel Injection in HIV-related Lipoatrophy
Combined antiretroviral therapy (cART) is associated with facial lipoatrophy, which is potentially stigmatizing for HIV-positive patients.
- Conditions
- HIV Infection, Antiretroviral Side Effects, Lipodystrophy Syndrome Related to HIV Infection
- Trial name
- LIPOPHILL (NCT01077765)
- Testing
- Eutrophill
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Atopic Dermatitis
Effects of Abrocitinib in Subjects With Atopic Dermatitis With an Unsatisfactory Response After Treatment With Dupilumab
This is a single-arm, open-label study that will examine the effect of abrocitinib in subjects with atopic dermatitis.
- Trial name
- NCT05602207
- Testing
- Abrocitinib
- Where
- 12 sites in United States, Canada
- Volunteers
- 24 people
- Sponsor
- Innovaderm Research Inc.
Actinic Keratosis
Activity & Safety Study of KX2-391 Ointment in Participants With Actinic Keratosis on the Face or Scalp
In this study, the activity, safety, and pharmacokinetics (PK) of KX2-391 Ointment was evaluated in adult participants with a clinical diagnosis of stable, clinically typical actinic keratosis (AK) on the face or scalp.
- Trial name
- NCT02838628
- Testing
- 50 mg of KX2-391 Ointment 1%
- Where
- 16 sites in United States
- Volunteers
- 168 people
- Sponsor
- Almirall, S.A.
Facial Lipoatrophy (FLA)
Evaluation of HA Dermal Fillers in the Treatment of Pathological Facial Lipoatrophy
Facial lipoatrophy (FLA) refers to the loss of adipose tissue and is manifested by flattening or indentation of convex contours of the face.
- Trial name
- HAtrophy (NCT05776836)
- Testing
- Dermal filler
- Where
- 3 sites in France
- Volunteers
- 30 people
- Sponsor
- Symatese
Actinic Keratosis (AK)
Outcomes Associated With Tirbanibulin for Large Field Application on the Face in the U.S (CLEAR)
The goal of this observational study is to learn about the effectiveness of tirbanibulin among adult subjects with actinic keratosis (AK) lesions in the face.
- Trial name
- CLEAR (NCT07657988)
- Testing
- Tirbanibulin
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Avant Health LLC
Hyperpigmentation
Efficacy and Tolerability of the Tested Formula After 3 Months in Treatment of Facial Hyperpigmentation of 3 Origins
The objective of this study is to evaluate the efficacy, cosmetic acceptability and improvement of the stigmatization of the tested product (2039125 03) used bis in die (BID) for 3 months in adult patients suffering from mild to…
- Trial name
- NCT06268496
- Testing
- serum formula 2039125 03
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Keratosis, Actinic
A Study to Assess Recurrence of Actinic Keratosis in Participants Treated With Methyl Aminolevulinate Hydrochloride Cream or Vehicle Cream Who Achieved Complete Response to Treated Lesions in Earlier Study
The primary purpose for this study is to assess recurrence of Actinic Keratosis in participants achieving complete response treated in earlier study.
- Trial name
- NCT04269395
- Testing
- MAL Cream, Vehicle cream
- Where
- 53 sites in United States, Puerto Rico
- Volunteers
- 125 people
- Sponsor
- Galderma R&D
Craniofacial Microsomia, Hemifacial Microsomia
Craniofacial Microsomia: Longitudinal Outcomes in Children Pre-Kindergarten (CLOCK)
This study is a multi-center, longitudinal cohort study of 125 infants with craniofacial microsomia (CFM) and 100 infants without craniofacial anomalies.
- Conditions
- Craniofacial Microsomia, Hemifacial Microsomia, Oculo-Auriculo-Vertebral-Syndrome, Goldenhar Syndrome
- Trial name
- CLOCK (NCT02224677)
- Where
- 5 sites in United States
- Volunteers
- 417 people
- Sponsor
- Seattle Children's Hospital
Actinic Keratosis, Keratosis, Actinic
Study to Evaluate Safety and Tolerability of BF-200 ALA (Ameluz®) for Photodynamic Therapy in the Treatment of the Expanded Field of Actinic Keratosis on Face and Scalp
The aim of the study is to evaluate the safety and tolerability of PDT for treatment of mild to severe actinic keratosis on the face and scalp in the expanded treatment field using 3 tubes of BF-200 ALA 10% gel (Ameluz®) in…
- Conditions
- Actinic Keratosis, Keratosis, Actinic, Keratosis
- Trial name
- NCT05060237
- Testing
- BF-200 ALA and red light LED lamp
- Where
- 9 sites in United States
- Volunteers
- 112 people
- Sponsor
- Biofrontera Bioscience GmbH
Acne Vulgaris
The Functional and Emotional Benefits of Replenix Power of Three With Resveratrol
A Randomized, Investigator Blinded, Single Site, Three Arm Clinical Study to Assess the Functional and Emotional Benefits of Replenix Power of Three Cream with Resveratrol , Replenix Power of Three Cream with Resveratrol with…
- Trial name
- NCT03563365
- Testing
- Replenix Power of 3 Cream with resveratrol, Adapalene and Benzoyl peroxide gel, 0.1%/2.5%
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Yardley Dermatology Associates
Acne Vulgaris
Teledermatology vs. Face-to-Face Visits in the Follow-Up of Patients With Acne
Acne vulgaris is a common cutaneous inflammatory condition of sebaceous follicles that can profoundly affect patients' quality of life, especially at a young age.
- Trial name
- NCT04593004
- Testing
- Teledermatology, Face-to-face consultation
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Rhytids, Skin Laxity
Safety and Efficacy of 2910 nm Fiber Laser Resurfacing and Laser-Coring
The primary objective of this clinical trial is to evaluate the safety and effectiveness of the 2,910 nm mid-infrared erbium-doped fluoride fiber glass laser (UltraClear, Acclaro Medical) for non-invasive dermatological aesthetic…
- Trial name
- NCT07254884
- Testing
- 2,910 nm mid-infrared erbium-doped fluoride fiber glass laser (UltraClear, Acclaro Medical)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- FA Corporation
Acne Vulgaris
Radiofrequency Treatment Versus Topical Therapy for Facial Acne Vulgaris
This clinical study will compare a radiofrequency (RF) treatment with a standard topical treatment for adults with mild-to-moderate inflammatory facial acne vulgaris.
- Trial name
- NCT07805655
- Testing
- Adapalene 0.1% and Benzoyl Peroxide 2.5% gel, Sequential Radiofrequency Treatment
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Jeisys Medical Inc
Face Rejuvenation, Neck Rejuvenation
Laser Treatment for Facial and Neck Rejuvenation
To assess the efficacy, safety, and patient satisfaction associated with the treatment of the face and neck with the 2,910nm mid-infrared UltraClear Laser System using both superficial epidermal ablation and deep ablative and…
- Trial name
- NCT05808842
- Testing
- CeraVe, CeraVe and Calecim
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff