Clinical trials: Facial Skin Condition
Breast Cancer
Comparison Trial of Letrozole to Anastrozole in the Adjuvant Treatment of Postmenopausal Women With Hormone Receptor and Node Positive Breast Cancer
Eligible patients will be post-menopausal hormone receptor- and lymph node-positive females who recently underwent primary surgery for breast cancer.
- Trial name
- FACE (NCT00248170)
- Testing
- Letrozole, Anastrozole
- Where
- 259 sites in United States, Australia and 18 more
- Volunteers
- 4,172 people
- Sponsor
- Novartis Pharmaceuticals
Laxity; Skin
Pivotal Study to Evaluate the Safety and Efficacy of a Micro-coring Device Treating Moderate to Severe Facial Wrinkles
Study evaluating the safety and efficacy of a micro-coring device for the treatment of moderate to severe cheek wrinkles.
- Trial name
- NCT03573271
- Testing
- MCD
- Where
- 5 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cytrellis Biosystems, Inc.
Rosacea
Phase 3 Efficacy and Safety Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea
This is a Phase 3 efficacy and safety study of CD07805/47 topical gel in subjects with facial erythema associated with rosacea. The study hypothesis is that CD07805/47 gel, applied topically once daily is more efficacious than…
- Trial name
- NCT01355471
- Testing
- CD07805/47 Gel
- Where
- 15 sites in United States, Canada
- Volunteers
- 293 people
- Sponsor
- Galderma R&D
Freckles
A Novel 532-nm Picosecond Laser for Freckle Treatment in Chinese Patients
The goal of this clinical trial was to learn if a novel laser device works as well and is as safe as an already approved laser device for removing freckles on the face.
- Trial name
- PICO-FRECK-C (NCT07352631)
- Testing
- Nd:YAG Picosecond Laser Therapy Device, Nd:YAG Picosecond Laser Therapy System
- Where
- 2 sites in China
- Volunteers
- 84 people
- Sponsor
- Beijing Hospital
Cutaneous Squamous Cell Carcinoma
Evaluating the Use of Photodynamic Therapy to Treat Facial Cutaneous Squamous Cell Carcinoma in Situ (SCCis)
The goal of this clinical trial is to test how safe and effective it is to treat early form of cancer cells found in the upper skin layer of the face, using a light-sensitive gel used in combination with a light source.
- Trial name
- NCT06577311
- Testing
- Aminolevulinic acid hydrochloride 10% topical gel with Red Light
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The Center for Clinical and Cosmetic Research
Acute Respiratory Failure
Noninvasive Positive Airway Pressure Ventilation and Risk of Facial Pressure Ulcers
To assess risk of skin pressure lesions in patients treated with noninvasive mechanical ventilation.
- Trial name
- NCT01828151
- Testing
- Noninvasive ventilation mask
- Where
- Italy
- Volunteers
- 170 people
- Sponsor
- Ospedale S. Giovanni Bosco
Acne Vulgaris
CD5789 (Trifarotene) Long Term Safety Study on Acne Vulgaris
Multi-center, open-label, non-comparative safety and efficacy study with 52 Weeks of treatment on the face and trunk for acne vulgaris.
- Trial name
- NCT02189629
- Testing
- CD5789 (trifarotene)
- Where
- 32 sites in United States, Czechia and 2 more
- Volunteers
- 453 people
- Sponsor
- Galderma R&D
Cicatrix, Lipodystrophy
Evaluating Performance and Safety of the Medical Device Jalucomplex in the Treatment of Facial and Neck Tissue Defects
The Research Question of the present study is the following: in a population of men and women presenting facial and neck dermal tissue defects (scars, hypertrophic scars, depressed plaques, and lipodystrophy defects) will linear…
- Conditions
- Cicatrix, Lipodystrophy, Plaque
- Trial name
- NCT05239351
- Testing
- Jalucomplex
- Where
- Romania
- Volunteers
- 48 people
- Sponsor
- I.R.A. Istituto Ricerche Applicate S.p.A.
Facial Aging, Skin Laxity
Quantified Evaluation of Noninvasive System Delivering Microwave Energy for Unwanted Fat Reduction and Skin Tightening in Asians.
The goal of this observational study is to evaluate the effectiveness and safety of microwave-assisted heating technology in facial fat reduction and skin tightening in Asians. The main questions it aims to answer are: 1.
- Conditions
- Facial Aging, Skin Laxity, Cheek Wrinkles
- Trial name
- NCT06925074
- Where
- Taiwan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Chang Chang Cheng
Laxity; Skin
Combination Therapy for Rejuvenation of the Lower Face and Neck
An investigator initiated trial in which 20 subjects with moderate to severe changes of the jawline, neck and décolletage will undergo combination treatment to achieve comprehensive rejuvenation of the jawline and neck.
- Trial name
- NCT04102670
- Testing
- Ultherapy, Xeomin, Belotero Balance
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nashville Centre for Laser and Facial Surgery
Breast Cancer
Physical Exercise for Breast Cancer Survivors: Face-to-face Versus Home-based
The present investigation is a pilot feasibility study that aims to compare a physical exercise intervention in a face-to-face context (considered state of the art) with a physical exercise intervention in a distance context…
- Trial name
- On4Rehab (NCT05071560)
- Testing
- Combined exercise training
- Where
- Portugal
- Volunteers
- 12 people
- Sponsor
- Associacao de Investigacao de Cuidados de Suporte em Oncologia
Healthy Condition
A Multicenter, Prospective Observational Study to Evaluate the Incidence of Delayed-onset Nodules of YVOIRE Y-Solution 360, YVOIRE Y-Solution 540 or YVOIRE Y-Solution 720 Injected Into the Facial Skin Layer.
This is an observational study to evaluate the incidence of delayed-onset nodules of YVOIRE Y-Solution 360, YVOIRE Y-Solution 540 or YVOIRE Y-Solution 720 injected into the facial skin layer.
- Trial name
- NCT04738019
- Testing
- Medical examination or treatment.
- Where
- South Korea
- Volunteers
- 1,022 people, healthy volunteers welcome
- Sponsor
- LG Chem
Melasma
Treatment w/ Tri-Luma® Cream & Intense Pulsed Light (IPL) vs a Mild Inactive Control Cream & Intense Pulsed Light (IPL) in Melasma
This study is to evaluate the efficacy and safety of Tri-Luma® Cream (fluocinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05%) when used sequentially with a series of intense pulsed light (IPL) treatments in Subjects…
- Trial name
- NCT00669071
- Testing
- Fluocinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05%, Cetaphil® Moisturizing Cream as Inactive Control
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- Galderma R&D
Postoperative Bleeding, Skin Cancer Face
Tranexamic Acid in Nasal Mohs Reconstruction
This study will be a prospective randomized control trial to evaluate the effects of subcutaneously administered TXA among patients undergoing nasal Mohs reconstruction with local flaps at VUMC.
- Trial name
- NCT06057675
- Testing
- Treatment (tranexamic acid and 1% lidocaine with 1:100,000 epinephrine), Control (1% lidocaine with 1:100,000 epinephrine)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Melasma
Tranexamic Acid With Microneedling in Melasma
Topical tranexamic, a hydrophilic molecule, can't pass the lipid barriers of the stratum corneum and it's also not retained in adequate amount in the epidermis to enter the melanocytes, so there's a difficulty in the effective…
- Trial name
- NCT05909072
- Testing
- Hyaluronic acid combined with tranexamic acid microneedling, tranexamic acid microneedling
- Volunteers
- 27 people
- Sponsor
- Zagazig University
Healthy
A Study of Two Facial Sunscreens to Assess Its Effect in Improving Hydration, Skin Barrier Function, and Skin Tone Uniformity Under Controlled and Normal Conditions of Use on the Face by Adult Participants
The purpose of this study is to evaluate the safety and efficacy of 02 facial sunscreens (investigational products [IPs]) under controlled and normal conditions of use on the face for 28 and 56 days, respectively.
- Trial name
- NCT05972434
- Testing
- Sunscreen A, Sunscreen B
- Where
- Brazil
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Wrinkles, Rhytids
Evaluation of the Ulthera® System for Treatment of the Face and Neck
Up to 15 subjects will be enrolled. Enrolled subjects will receive one Ulthera® treatment on the face and neck. Follow-up visits will occur at 45, 90 and 180 days post-treatment.
- Conditions
- Wrinkles, Rhytids, Skin Laxity
- Trial name
- NCT01713907
- Testing
- Ulthera® Treatment
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc
Melasma
Efficacy of Eflornithine Hydrochloride Cream in the Treatment of Melasma: A Randomized, Double-blinded, Split-face Controlled Study
The goal of this clinical trial is to learn if Eflornithine hydrochloride cream works to treat melasma in adults, in comparison to Hydroquinone cream. It will also learn about the safety of Eflornithine hydrochloride cream.
- Trial name
- NCT06957834
- Testing
- Eflornithine hydrochloride cream, Hydroquinone cream
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- National Skin Centre
Erythema, Skin Recovery
A Study to Gain Information How Well Dexpanthenol Derma Cream Helps the Face Skin to Recover After Cosmetic Lasering
In this study, researchers want to learn more about the effect of dexpanthenol cream on skin recovery and reduction of skin rash after a dermatological procedure (ablative laser) on the face for treatment of fine wrinkles, scars…
- Trial name
- NCT03852563
- Testing
- BAY207543 (Bepanthol), Semisolid vaseline
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bayer
Understanding Skin Health and the Microbiome, Microbial Colonization
Survey of the Facial Bacteriome
The microbiome can affect skin health from the gut-skin axis, from environmental exposure, and topical treatments. Decreasing biodiversity of skin microbiota has been linked to inflammatory conditions, allergies, and skin health.
- Trial name
- NCT04180748
- Testing
- fluorescence imaging with 405nm light
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto