Clinical trials: Facial Skin Condition
Actinic Keratosis
Long-term Effects of Imiquimod and Diclofenac in Actinic Keratoses
This clinical trial serves the purpose to compare the long-term effects of a treatment of actinic keratosis - your skin disorder - using Aldara® 5% cream or Solaraze® 3% gel on the face or the scalp.
- Trial name
- LEIDA (NCT00777127)
- Testing
- Imiquimod, Diclofenac
- Where
- 26 sites in Austria, France and 1 more
- Volunteers
- 258 people
- Sponsor
- MEDA Pharma GmbH & Co. KG
Pigmentation Disorder
Fractional Laser as Treatment Option for Various Pigment Disorders (Fractional-3)
The purpose of this study is to determine whether the use of non-ablative fractional laser is safe and effective in the treatment of melasma.
- Trial name
- NCT01085279
- Testing
- Fraxel Restore, Solta Medical Inc. (Non-ablative fractional laser), Modified Kligman's formula (Triple topical therapy)
- Where
- Netherlands
- Volunteers
- 29 people
- Sponsor
- Netherlands Institute for Pigment Disorders
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Skin Aging, Sagging Skin
Facial Contouring With Monopolar RF and Continuous Water Cooling
The goal of this clinical trial is to assess whether a single RF-CWC (radiofrequency - continous water cooling) session can produce significant improvements in jawline contour and facial volume in women aged 38-50 years over 8…
- Conditions
- Skin Aging, Sagging Skin, Laxity; Skin
- Trial name
- NCT07317089
- Testing
- RF-CWC
- Where
- South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Acne Vulgaris on the Face
Efficacy and Tolerability of DispersinB Acne Cleanser in the Treatment of Mild to Moderate Acne Vulgaris
This is a single-center study using intra-individual comparison (right half-face versus left half-face) to evaluate the efficacy and tolerability of DispersinB Acne Cleanser for treatment of acne in adults.
- Trial name
- NCT06729450
- Testing
- DispersinB Acne Cleanser
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Kane Biotech Inc
Actinic Keratoses
Single-Center Study Evaluating Systemic Exposure and Safety of KX2-391 Ointment 1% on the Face or Balding Scalp in Subjects With Actinic Keratosis
This Phase I study is designed to evaluate the systemic exposure and safety of KX2-391 Ointment in adult subjects when applied to an area of skin containing at least 5 clinically typical, visible, and discrete Actinic Keratosis…
- Trial name
- NCT03575780
- Testing
- KX2-391 Ointment 1%
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Athenex, Inc.
Systemic Sclerosis, Face
Efficacy of a Personalized Rehabilitation Program of Facial Involvement in Systemic Sclerosis
Systemic sclerosis is a rare autoimmune disorder characterized by microangiopathy, activation of the immune system, and sclerosis of tissues including the skin. Facial involvement is frequent and disabling.
- Conditions
- Systemic Sclerosis, Face, Facial Involvement, Rehabilitation
- Trial name
- PREVISS (NCT05177380)
- Testing
- Personalized rehabilitation program of facial involvement in systemic sclerosis, Delivery of a standard prescription for facial rehabilitation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Diaper Dermatitis, Perioral Dermatitis
Effect of Cream Paste Containg Pleuran on Selected Skin Dermatoses (Neonatal Pustulosis, Diaper Dermatitis, Perioral Dermatitis).
In this multicentre, prospective clinical research conducted in outpatient healthcare facilities, the investigators studied the effect of novel cosmetic product Imunoglukan P4H® ACUTE! cream paste in children with neonatal…
- Conditions
- Diaper Dermatitis, Perioral Dermatitis, Neonatal Pustulosis, Periorificial Dermatitis
- Trial name
- ECESID (NCT07479004)
- Testing
- Cosmetic product: Imunoglukan P4H® ACUTE! cream-paste
- Where
- 15 sites in Slovakia
- Volunteers
- 110 people
- Sponsor
- Pleuran, s.r.o.
Acne Vulgaris
Teledermatology vs. Face-to-Face Visits in the Follow-Up of Patients With Acne
Acne vulgaris is a common cutaneous inflammatory condition of sebaceous follicles that can profoundly affect patients' quality of life, especially at a young age.
- Trial name
- NCT04593004
- Testing
- Teledermatology, Face-to-face consultation
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Healthy
Tolerability Study of the Application of a 3M Microstructure Transdermal System
The purpose of this study is to evaluate the safety and tolerability of an experimental device that introduces microscopic channels into the skin.
- Trial name
- NCT01257763
- Testing
- Transdermal Microchannel Skin System
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Actinic Keratosis of Face and Scalp
Phase 3 - Evaluation of Veregen® 10% Ointment as New Herbal Topical Treatment for Actinic Keratosis
The goal of this clinical trial is to show superiority of Veregen® 10% ointment to Placebo measured by complete (100%) clearance of a pre-defined treatment area (TA) following a treatment period of 12 weeks and a 4-weeks…
- Trial name
- EXACT-1 (NCT07137819)
- Testing
- Topical treatment
- Where
- Germany
- Volunteers
- 280 people
- Sponsor
- Aresus Pharma GmbH
Acne Vulgaris
Bioequivalence Study of Adapalene Gel 0.3% in Subjects With Facial Acne Vulgaris
To evaluate the therapeutic equivalence and safety of Adapalene Gel 0.3% (Aleor Dermaceuticals Limited, India) and Differin® (Adapalene) Gel 0.3% (Galderma Laboratories, LP USA) in the treatment of acne vulgaris.
- Trial name
- NCT03650361
- Testing
- Adapalene Gel 0.3%, Differin 0.3% Topical Gel
- Where
- 10 sites in United States, Belize
- Volunteers
- 755 people
- Sponsor
- Aleor Dermaceuticals Limited
Skin Pigmentation Over Contour Deformities of Face, Trauma, Rhomberg Disease
Long Term Effects on Skin Hyper Pigmentation With and Without Mesenchymal Stem Cell Enriched Adipose Tissue Grafting for "Contour Deformities With Pigmentary Changes on Face"
MSCs one injected along with fat, regulate pigmentation over the contour defects of face
- Trial name
- MSCs (NCT03564808)
- Testing
- MSC
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- King Edward Medical University
Surgery, Cancer of Skin
Computer Modelling to Plan Surgical Reconstruction
The aim of this study is to improve patient satisfaction and outcomes in facial reconstructive surgery by using 3D clinical photography and computer modelling to help illustrate and plan the patients' reconstructive journey.
- Trial name
- NCT04968704
- Testing
- 3D photography and computer modelling
- Volunteers
- 10 people
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Healthy, Melasma (Facial Melasma)
COMPARISON OF A COSMETIC SERUM AND 4% HYDROQUINONE FOR TREATING MELASMA OVER 84 DAYS
The goal of this clinical trial is to compare the dermatological tolerance and skin-lightening efficacy of a cosmetic depigmenting serum to a 4% hydroquinone-based product in adult male and female subjects aged 18-65 years with…
- Conditions
- Healthy, Melasma (Facial Melasma), Epidermal Melasma
- Trial name
- NCT07071363
- Testing
- Depigmenting Cosmetic Serum (Applied Morning and Evening)
- Where
- Mauritius
- Volunteers
- 40 people
- Sponsor
- Laboratoire Dermatologique ACM
Skin Manifestations
Study to Evaluate the Safety and Effectiveness of GP0116
This is a prospective, randomized, evaluator-blinded, comparator-controlled, parallel group, multicenter study in the U.S. for correction of moderate to severe dynamic facial wrinkles and folds, such as nasolabial folds (NLFs).
- Trial name
- NLF (NCT05987163)
- Testing
- GP0116, Active Comparator: FDA approved dermal filler device (RHA 3)
- Where
- 19 sites in United States, Puerto Rico
- Volunteers
- 186 people
- Sponsor
- Galderma R&D
Atopic Dermatitis
Efficacy and Safety of Pimecrolimus Cream 1% in Patients (2 to 11 Years Old) With Mild to Moderate Facial Atopic Dermatitis
This study is not being conducted in the United States of America (USA). Atopic dermatitis, also called eczema, is characterized by redness, papulation (skin elevation) and pruritus (skin itching).
- Trial name
- NCT00130364
- Testing
- Pimecrolimus
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Novartis
Acne Vulgaris
Comparison of Malassezia Spp Proportions in Inflammatory and Non Inflammatory Facial Acne Vulgaris Lesions
Acne vulgaris (AV) is a common inflammatory condition involving pilosebaceous unit. The pathogenesis of acne is multifactorial and skin microbiome is considered to be one of the key factors that aggravate inflammation.
- Trial name
- NCT04367584
- Testing
- Clinical and laboratory examination
- Where
- Indonesia
- Volunteers
- 120 people
- Sponsor
- Universitas Indonesia
Actinic Keratosis
Pharmacokinetics of Ingenol Mebutate Gel in Actinic Keratosis Under Maximum Use Conditions
This is an open-label, uncontrolled, non-randomised multi-centre trial in which 3 parallel groups will be enrolled. The trial includes three active treatment groups.
- Trial name
- NCT02124239
- Testing
- Ingenol mebutate
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- LEO Pharma
Craniofacial Microsomia, Hemifacial Microsomia
Craniofacial Microsomia: Longitudinal Outcomes in Children Pre-Kindergarten (CLOCK)
This study is a multi-center, longitudinal cohort study of 125 infants with craniofacial microsomia (CFM) and 100 infants without craniofacial anomalies.
- Conditions
- Craniofacial Microsomia, Hemifacial Microsomia, Oculo-Auriculo-Vertebral-Syndrome, Goldenhar Syndrome
- Trial name
- CLOCK (NCT02224677)
- Where
- 5 sites in United States
- Volunteers
- 417 people
- Sponsor
- Seattle Children's Hospital