Clinical trials: Facial Skin Condition
Acne Vulgaris
Silymarin Cream Versus Salicylic Acid in Treatment of Acne Vulgaris
Acne vulgaris is a disease of the pilosebaceous unit that causes noninflammatory lesions (open and closed comedones), inflammatory lesions (papules, pustules, and nodules), and varying degrees of scarring.
- Trial name
- NCT04490967
- Testing
- Silymarin, Salicylic acid
- Volunteers
- 30 people
- Sponsor
- Assiut University
Atopic Dermatitis
Comparison Between Asynchronous Online Care Model With Usual In Office Care for the Management of Atopic Dermatitis
The purpose of this study is to determine if an asynchronous online model of teledermatology can achieve similar clinical outcomes as compared to conventional in-office care for the management of atopic dermatitis.
- Trial name
- NCT00985894
- Testing
- Online Teledermatology Care, Conventional in Office Care
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- University of California, Davis
Actinic Keratosis
A Long Term Follow up Study of Patients Who Have Completed the PEP005-016 or PEP005-025 Studies
This study is designed to follow up patients who have achieved complete clearance of AK lesions at the Day 57 visit having completed the PEP005-016 or PEP005-025 studies over a 12 month period to assess both recurrence of Actinic…
- Trial name
- NCT00953732
- Testing
- Lesion count
- Where
- 42 sites in United States, Australia
- Volunteers
- 117 people
- Sponsor
- Peplin
Rosacea, Rosacea Subtype 1 (Erythematotelangiectatic)
Brimonidine 0.33% for Rosacea-Related Facial Erythema
This study looks at whether a topical gel called 0.33% brimonidine can reduce persistent facial redness caused by rosacea. The study was carried out in two parts.
- Trial name
- NCT07431476
- Testing
- Brimonidine 0.33% gel
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul Training and Research Hospital
Breast Cancer
Physical Exercise for Breast Cancer Survivors: Face-to-face Versus Home-based
The present investigation is a pilot feasibility study that aims to compare a physical exercise intervention in a face-to-face context (considered state of the art) with a physical exercise intervention in a distance context…
- Trial name
- On4Rehab (NCT05071560)
- Testing
- Combined exercise training
- Where
- Portugal
- Volunteers
- 12 people
- Sponsor
- Associacao de Investigacao de Cuidados de Suporte em Oncologia
Erythema, Telangiectasis
The Effect of 16-week Dietary Intake of Food Supplements Containing Collagen and MSM on Facial Erythema and Other Skin Parameters
The aim of this study is to compare the effects of 16 weeks of daily dietary supplementation with two investigational products containing collagen, methylsulfonylmethane (MSM), and vitamin C on skin parameters in comparison to a…
- Conditions
- Erythema, Telangiectasis, Skin Redness
- Trial name
- TO-COSKIN4 (NCT07345195)
- Testing
- CPMSM-HD, CPMSM-LD
- Where
- Slovenia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- VIST - Faculty of Applied Sciences
Rosacea
To Evaluate the Therapeutic Equivalence and Safety in Treatment of Moderate Facial Rosacea
To demonstrate the superiority of the efficacy of the test and reference products over that of the placebo control in the treatment of moderate facial rosacea.
- Trial name
- NCT03689010
- Testing
- Azelaic acid foam 15%, Finacea® (Azelaic acid Foam) 15%, Vehicle of the test product
- Where
- United States
- Volunteers
- 1,116 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Wrinkle, Elastic Skin
Straberi Epistamp Needling Treatment For Skin Rejuvenation
This pilot study will expand knowledge and application needling using the Epistamp device for the improvement of a new vitalized epidermal layer with new vibrant active cells, supported by more robust collagen and elastin fine…
- Conditions
- Wrinkle, Elastic Skin, Collagen Degeneration
- Trial name
- ESAA (NCT04742803)
- Testing
- Straberi Epistamp Microneedling Treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universal Skincare Institute
Rare Diseases, Marfan Syndrome
Marfan Syndrome (MFS) and Facial Dysmorphism: Non-invasive 3D Assessment
The goal of this study observational prospective study is to define the facial morphological features associated with Marfan syndrome (MFS). The main qustion it aims to answer are: 1.
- Trial name
- FACE (NCT05702476)
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- IRCCS Policlinico S. Donato
Seborrheic Keratosis
Study of A-101 for the Treatment of Seborrheic Keratosis
The purpose of this study is to evaluate the safety and dose-response of 2 concentrations of A-101 versus a vehicle control in the treatment of seborrheic keratosis.
- Trial name
- NCT02260180
- Testing
- A-101
- Where
- 4 sites in United States
- Volunteers
- 119 people
- Sponsor
- Aclaris Therapeutics, Inc.
Skin Manifestations
Split-face Tolerability Comparison Between MetroGel® 1% vs Finacea® 15% in Subjects With Healthy Skin
The purpose of this study is to compare the tolerability of MetroGel® 1% to Finacea® 15% in subjects with healthy skin applied according to product labeling for three weeks.
- Trial name
- NCT01139047
- Testing
- metronidazole 1% gel, azelaic acid 15% gel
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Collagen Degeneration, Wrinkle
The Effects of Almond on Facial Skin Collagen and Wrinkles
Investigate the effects of almond consumption on collagen production, elastin levels, wrinkles, and pigmentation among premenopausal women and postmenopausal women belonging to all Fitzpatrick skin types.
- Conditions
- Collagen Degeneration, Wrinkle, Pigmentation, Elastic Skin
- Trial name
- NCT06074276
- Testing
- Food: whole almonds, Food: non-nut snack
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Wrinkles, Rhytids
Evaluation of the Ulthera® System for Treatment of the Face and Neck
Up to 15 subjects will be enrolled. Enrolled subjects will receive one Ulthera® treatment on the face and neck. Follow-up visits will occur at 45, 90 and 180 days post-treatment.
- Conditions
- Wrinkles, Rhytids, Skin Laxity
- Trial name
- NCT01713907
- Testing
- Ulthera® Treatment
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc
Actinic Keratosis
Short-incubation Levulan Photodynamic Therapy Versus Vehicle for Face/Scalp Actinic Keratosis (AK)
The purpose of this study is to determine if Levulan Photodynamic Therapy (PDT) is safe and effective in the treatment of actinic keratosis when applied to broad areas on the face and scalp for 1, 2 and 3 hours.
- Trial name
- NCT01475955
- Testing
- Broad Area ALA 1-hour incubation, Broad Area ALA 2 hour incubation, broad area ALA 3-hour incubation
- Where
- 13 sites in United States
- Volunteers
- 235 people
- Sponsor
- DUSA Pharmaceuticals, Inc.
Skin Laxity
Lifting and Tightening of the Face and Neck Following an Increased Density Treatment
The purpose of this study is to evaluate the Ulthera® System for obtaining lift and tightening of the cheek tissue, reduction of jowling, and improving jawline definition and/or submental skin laxity when increased density…
- Trial name
- NCT01519206
- Testing
- Ulthera System Treatment
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc
Acne Vulgaris
Comparison of Nadifloxacin Cream Alone and With Benzoyl Peroxide Solution in the Treatment of Acne
The purpose of this study is to determine whether using of nadifloxacine 1% cream and benzoyl peroxide 5% solution together is more effective than using nadifloxacine alone in the treatment of mild to moderate facial acne.
- Trial name
- NCT00869492
- Testing
- benzoyl peroxide, nadifloxacine
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Marmara University
Vitiligo
A Study of ATI-50002 Topical Solution for the Treatment of Vitiligo
The main objective of this study is to assess the safety, tolerability and efficacy of ATI-50002 Topical Solution, 0.46% in subjects with non-segmental facial vitiligo.
- Trial name
- NCT03468855
- Testing
- ATI-50002 topical solution
- Where
- 5 sites in United States
- Volunteers
- 34 people
- Sponsor
- Aclaris Therapeutics, Inc.
Acne Vulgaris
Study of Oral Zileuton in the Treatment of Moderate to Severe Facial Acne Vulgaris
Tissue inflammation is a major component of the acne disease process. Leukotriene B4 (LTB4) is thought to be a major player in the development of tissue inflammation. Synthesis of LTB4 is controlled by the enzyme 5-lipoxygenase.
- Trial name
- NCT00098358
- Testing
- Zileuton
- Where
- 12 sites in United States
- Volunteers
- 90 people
- Sponsor
- Critical Therapeutics
Rosacea
Comparative Safety and Efficacy of Two Rosacea Products in the Treatment of Facial Erythema of Rosacea
To compare safety and efficacy of Perrigo's rosacea drug product compared to an FDA approved rosacea drug product in the treatment of facial erythema of rosacea.
- Trial name
- NCT02385240
- Testing
- Brimonidine Topical Gel, 0.33 percent (Perrigo), Brimonidine Topical Gel, 0.33 percent (Reference)
- Volunteers
- 552 people
- Sponsor
- Padagis LLC
Skin Cancer
Comparative Retrospective Analysis of Skin Tumors of the Eyelids and Face in 2 Brussels University Hospitals Over 5 Years in Dermatology or Ophthalmology
Skin cancers are the most common of all cancers. Their incidence has increased sharply over the decades.This increase in incidence partly reflects an aging population and behavioral patterns such as repeated exposure to the sun.
- Trial name
- NCT04886908
- Testing
- Data extraction from medical files
- Where
- Belgium
- Volunteers
- 373 people
- Sponsor
- Brugmann University Hospital