Clinical trials: Facial Swelling
Bleeding, Bruising Face
Intravenous Tranexamic Acid During Rhytidectomy
This is a prospective, randomized, double-blind study investigating whether intravenous tranexamic acid has any effect on rhytidectomy surgery, or the subsequent postoperative sequelae.
- Conditions
- Bleeding, Bruising Face, Swelling Lips & Face
- Trial name
- NCT03970213
- Testing
- Tranexamic Acid 100Mg/Ml Inj Vil 10Ml, Normal Saline 0.9% Infusion Solution Bag
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Glasgold Group Plastic Surgery
Postoperative Care/Methods, Drainage/Methods
The Effect of Manual Lymphatic Drainage on Swelling After Orthognathic Surgery - a Qualitative and 3D Facial Analysis.
Introduction / background Orthognathic surgery is an operation in which one or both jaws are fixed in a more favorable position performed by an osteotomy.
- Conditions
- Postoperative Care/Methods, Drainage/Methods, Edema/Prevention & Control, Orthognathic Surgical Procedures/Adverse Effects
- Trial name
- NCT03682159
- Testing
- manual lymphatic drainage
- Where
- Belgium
- Volunteers
- 26 people
- Sponsor
- University Hospital, Ghent
Skin Aging
Effectiveness and Safety of Cellbooster Shape in Healthy Subjects
SUISSELLE has developed a CE marketed (2021) HA-based superficial epidermis/dermis injection filler and skinbooster product, Cellbooster® Shape (CBS). CBS is produced using patented CHAC Technology.
- Trial name
- NCT07636512
- Testing
- Skin booster injection (CBS)
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Suisselle
Pain, Postoperative, Edema
Effectiveness of Light-emitting Diode (LED) Photobiomodulation in the Extraction of Retained Lower Third Molars
In dentistry, one of the most common surgical procedures is the removal of included third molars. This surgery generates great morbidity to patients for causing pain, edema and trismus due to surgical trauma.
- Conditions
- Pain, Postoperative, Edema, Trismus, Quality of Life
- Trial name
- NCT03442166
- Testing
- LED group
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Postoperative Morbidity
Effects of Hyaluronic Acid Complex and Dexamethasone on Pain, Swelling, and Trismus After Mandibular Third Molar Surgery
This study aimed to comparatively evaluate the effects of a hyaluronic acid complex and dexamethasone on postoperative pain, swelling, and trismus following mandibular third molar surgery, compared with a control group.
- Trial name
- NCT07853196
- Testing
- Hyaluronic Acid Complex, Dexamethasone, Absorbable Hemostatic Gelatin Sponge (SPONGOSTAN™ Dental)
- Where
- Cyprus
- Volunteers
- 45 people
- Sponsor
- Cyprus Health and Social Sciences University
Impacted Mandibular Third Molar Extraction, Post Operative Complications
A Comparison of Recovery After Impacted Wisdom Tooth Removal
Justification of the Study There is a high prevalence of impacted third molars, often accompanied by a range of postoperative complications.
- Trial name
- CESE-3M (NCT07304882)
- Testing
- serratiopeptidase, Escin, Conventional drugs
- Where
- Yemen
- Volunteers
- 24 people
- Sponsor
- University of Science and Technology, Yemen
Impacted Mandibular Third Molar
The Effect of Topical Application of Hyaluronic Acid and Melatonin Mixture Following Surgical Extraction of Impacted Mandibular Third Molars .
This randomized controlled clinical trial aims to evaluate the clinical and radiographical effects of the application of a mixture of hyaluronic acid and melatonin after surgical extraction of impacted mandibular third molars.
- Trial name
- NCT07735806
- Testing
- Hyaluronic acid and Melatonin mixture, Gel foam
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kafrelsheikh University
Molar, Fourth, Extracting Own Teeth
Effects of the Application of a Hyper-oxygenated Gel After Oral Surgery
The goal of this clinical trial is to evaluate whether the topical application of Novox® Drop on surgical wounds after the extraction of lower third molars can have a clinical advantage.
- Conditions
- Molar, Fourth, Extracting Own Teeth, Edema Face, Pain
- Trial name
- NCT06458478
- Testing
- Hyper-oxygenated gel, glycerin based gel
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- Azienda Ospedaliera di Perugia
Impacted Mandibular Third Molar, Postoperative Pain
Effect of Preoperative Long-Acting Corticosteroids on Pain, Swelling, and Trismus After Impacted Lower Third Molar Surgery
This study evaluated whether giving a single dose of long-acting corticosteroids before wisdom tooth surgery reduces pain, facial swelling, and limited jaw opening (trismus) after surgery.
- Conditions
- Impacted Mandibular Third Molar, Postoperative Pain, Trismus, Facial Swelling
- Trial name
- NCT07450638
- Testing
- Dexamethasone 8 mg IM, Normal Saline IM
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al Salam University
Periodontal Pocket, Swelling Lips & Face
The Efficacy of Autogenous Dentin Graft in Mandibular Wisdom Tooth Extraction
The study aimed to investigate clinical effect of autogenous dentin graft on patients following mandibular wisdom tooth extraction.
- Conditions
- Periodontal Pocket, Swelling Lips & Face, Trismus, Pain, Acute
- Trial name
- NCT06073639
- Testing
- Autogenous dentin graft
- Where
- Vietnam
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Gastrointestinal Symptoms, Bloating
A Clinical Trial to Evaluate the Effects of Super Liver Liquid Drops on Gut Health, Digestive Comfort, and Daily Energy Levels
This is a decentralized (fully virtual), single-group, open-label, prospective clinical trial evaluating the effects of Super Liver Liquid Drops, a liquid botanical dietary supplement, on gut health, digestive comfort, energy…
- Conditions
- Gastrointestinal Symptoms, Bloating, Digestive Discomfort, Low Energy Levels
- Trial name
- NCT07742657
- Testing
- Super Liver
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- SuperBonsai Inc.
Impacted Mandibular Third Molar, Postoperative Pain
Effects of Platelet-Rich Fibrin After Mandibular Third Molar Surgery in Smokers and Nonsmokers
Mandibular third molar surgery is commonly associated with postoperative pain, swelling, and trismus. Platelet-rich fibrin (PRF) has been proposed as a biological adjunct to improve postoperative healing; however, its…
- Conditions
- Impacted Mandibular Third Molar, Postoperative Pain, Trismus, Facial Swelling
- Trial name
- NCT07604584
- Testing
- Platelet-Rich Fibrin
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara University
Postoperative Pain, Edema
Bromelain and Escin in the Reduction of Postoperative Sequelae in Periodontal and Implant Surgery
A randomized clinical trial will be performed in parallel, placebo controlled, triple-blind to evaluate the effectiveness of the association Bromelina and Horse-chestnut (titrated in escin) (Noflogo®, Mavenpharma s.r.l., Rome…
- Conditions
- Postoperative Pain, Edema, Swelling Lips & Face
- Trial name
- NCT04657874
- Testing
- Bromelains and Escin Oral Tablet
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of L'Aquila
Tooth Diseases, Piezoelectric Technique
A New Piezoelectric Technique in Third Molar Surgery
The present study aims to analyze the effect of the piezoelectric technique in third molar surgery in terms of facial swelling, trismus and pain in a split-mouth randomized controlled clinical trial
- Conditions
- Tooth Diseases, Piezoelectric Technique, Tooth, Impacted, Tooth Extraction Status Nos
- Trial name
- NCT06212232
- Testing
- Piezoelectric surgery
- Where
- Italy
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Amerigo Giudice
Facial Injuries, Pain
Topical Dexamethasone/Diclofenac Hydrogel for Postoperative Pain and Swelling in Facial Soft Tissue Injuries
This randomized, controlled clinical trial will evaluate the clinical effects of a topical thermoresponsive hydrogel containing dexamethasone sodium phosphate and diclofenac sodium on postoperative pain and facial swelling in…
- Conditions
- Facial Injuries, Pain, Swelling
- Trial name
- NCT07853664
- Testing
- Poloxmer F-127 Hydrogel with Dexamethasone/Diclofenac
- Where
- Yemen
- Volunteers
- 52 people
- Sponsor
- Thamar University
Pain Postoperative, Swelling Lips & Face
Postoperative Symptoms Following Endodontic Microsurgery
Aims: The purpose of this randomized clinical trial is to assess and compare the post operative pain, swelling and quality of life after endodontic microsurgery using either conventional osteotomy or piezoelectric osteotomy .
- Trial name
- NCT05898035
- Testing
- Endodontic Microsurgery
- Where
- Jordan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Wisdom Teeth, Edema Face
Comparison of the Effects of Intraoral Postoperative Dexamethasone Applications After Mandibular Third Molar Surgery
The aim of this study is to comparatively evaluate the effects of dexamethasone injected into the masseter muscle and pterygomandibular space after mandibular third molar surgery on postoperative pain, edema, trismus and quality…
- Conditions
- Wisdom Teeth, Edema Face, Trismus, Pain, Postoperative
- Trial name
- NCT06604286
- Testing
- In this group, patients received 8 mg IM dexamethasone injection into the masseter muscle after impacted tooth surgery., 8 mg IM dexamethasone injection into the pterygoid cavity after impacted tooth surgery.
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Afyonkarahisar Health Sciences University
Facial Swelling, Tooth Position Anomalies
Platelet-Rich Fibrin as an Antibiotic Delivery Vehicle in Mandibular Third Molar Surgery
The present study aims to evaluate the effect of platelet-rich fibrin (PRF) used as a local antibiotic delivery vehicle on postoperative outcomes, including facial swelling, trismus, and pain, following mandibular third molar…
- Conditions
- Facial Swelling, Tooth Position Anomalies, Tooth, Impacted, Tooth Extraction Status Nos
- Trial name
- NCT07764757
- Testing
- Antibiotic-enriched Platelet-Rich Fibrin (PRF), Platelet-Rich Fibrin (PRF)
- Where
- Italy
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Amerigo Giudice
Tooth Disease, Piezoelectric Technique
Comparison of Piezoelectric and Conventional Surgery for Germectomy of the Lower Third Molar
The main objective of the study is to compare the effects of the piezoelectric surgery and the traditional technique on soft tissue edema in patients undergoing bilateral germectomy of mandibular third molars
- Conditions
- Tooth Disease, Piezoelectric Technique, Tooth Impacted, Tooth Extraction Status Nos
- Trial name
- Germectomy (NCT06778590)
- Testing
- Piezoelectric technique in third molar germectomy, Traditional technique in third molar germectomy
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Amerigo Giudice
Swelling Lips &Amp; Face, Pain
Combination of Mixed Drugs vs Ibuprofen: a Randomized Clinical Trial
Combination of vitamins and melatonine compared with the conventional use of ibuprofen after surgical third molar extraction
- Conditions
- Swelling Lips &Amp; Face, Pain, Trismus
- Trial name
- CoctailRCT (NCT07133360)
- Testing
- Third molar extraction
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid