Clinical trials: Fall, open to volunteers
Cerebral Palsy (CP)
Effect of Transcranial Direct Current Stimulation on Risk of Falling in Cerebral Palsy Spastic Hemiplegic Children
The purpose of this study was to determine: If there is an effect of transcranial direct current stimulation in improvement the functional balance in CP spastic hemiplegic children.
- Trial name
- NCT06730763
- Testing
- Transcranial direct current stimulation, Exercise
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Stroke
Effect of Sensorimotor Training Versus Dual-task Training
The aim of this study is to determine the comparative effects of sensorimotor training and dual-task training on propriocetion, balance, functional mobility and fall risk in stroke patients.
- Trial name
- NCT07628374
- Testing
- Sensorimotor Training, Dual-Task Training, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Parkinson Disease
Reducing Falls With Varenicline in Hypocholinergic Parkinson Disease
This trial aims to test whether one year of Varenicline, when compared to placebo, can reduce fall risk and show improvement in the ability to multitask while walking.
- Trial name
- CRANE (NCT06679374)
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Vikas Kotagal
Myeloid Chimerism
Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myeloid Chimerism Levels
Background: Sickle cell disease can often be treated with blood stem cell transplants. But for some people the disease returns. This study will give a second transplant to people whose disease has returned but still have some…
- Trial name
- NCT04008368
- Testing
- CliniMACS CD34 Reagent
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Accidental Fall
Effects of a Novel Perturbation Balance Training Program on Laboratory and Real-World Trip-Induced Losses of Balance and Falls Among Balance-Impaired Older Adults
The goal of this clinical trial is to learn if a novel balance training stepping exercise can reduce the risk of falling among adults over the age of 65.
- Trial name
- NCT07891637
- Testing
- Step Training, Treadmill Training, Otago Exercise Program
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Alzheimer Disease or Associated Disorder
Effects of Musical Intervention by a Therapist (IMT) on Falling Asleep and Behavioral Regulation in a Secure Care Unit (SCU)
This is a prospective, multicenter study designed to evaluate the benefits of an evening music-based intervention on sundowning syndrome in patients with Alzheimer's disease or related disorders in a Protect lLife Unit setting.
- Trial name
- DOUCE NUIT IMT (NCT07465783)
- Testing
- Test musicale intervention, Controle: audio book
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Older Adults, Exercise Training
Transfer Effects of Stationary Bicycle Perturbation Training on Older Adults' Cycling Skills
The Israeli research group of this trial has developed the Perturbation Stationary Bicycle Robotics (PerStBiRo) system that can challenge balance while sitting.
- Conditions
- Older Adults, Exercise Training, Bicycling
- Trial name
- BiPerAge (NCT06453473)
- Testing
- TSBR, PerTSBR
- Where
- 2 sites in Germany, Israel
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting
Impact of the Cionic Neural Sleeve on Mobility in Multiple Sclerosis
The purpose of this research is to support the clinical value of the Cionic Neural Sleeve for individuals diagnosed with multiple sclerosis (MS).
- Conditions
- Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Chronic Progressive
- Trial name
- NCT05964829
- Testing
- Cionic Neural Sleeve NS-100, Walking Program
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Cionic, Inc.
ELDERLY PEOPLE, Cognitive-motor Dual-task
The Effects of Cognitive-motor Dual-task Intervention on Fall Prevention Among Older Adults
1. Develop an evidence-based dual-task intervention programme incorporating gamification for fall risk reduction in older adults. 2. Examine the effects of the gamified dual-task intervention on fall risk in older adults. 3.
- Conditions
- ELDERLY PEOPLE, Cognitive-motor Dual-task, Fall Prevention, Intervention
- Trial name
- NCT07025278
- Testing
- Medium difficulty fixed priority group, Medium difficulty variable priority group
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Jinyao Wang
Parkinson Disease(PD)
Objective Mobility Assessment Using Wearable Technology for Clinical Application in Parkinson's Disease: From Validation to Fall Prediction
The main objective of this observational trial is to explore the validity and reliability of DANU smart socks when used for mobility assessments in people with Parkinson's.
- Trial name
- NCT07281755
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Northumbria University
COPD (Chronic Obstructive Pulmonary Disease), COPD
Balance Training Following Pulmonary Rehabilitation on Balance in People With Chronic Obstructive Pulmonary Disease (COPD)
This study aims to see if a co-designed balance training programme called Sport4Steadiness (S4S), is acceptable to people with COPD and if the study procedures, including recruitment and the collection of outcomes, is feasible.
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), COPD, Balance Exercise, Falls, Intervention
- Trial name
- B-PuRe (NCT07750821)
- Testing
- Sport4Steadiness
- Where
- 3 sites in United Kingdom
- Volunteers
- 77 people
- Sponsor
- Samantha Harrison
Elderly Population
Comparison of Square Stepping Exercise and Wobble Board Exercise in Elderly Population
Cognitive decline and balance issues are key contributors to falls. Square Stepping Exercise (SSE) and Wobble Board Exercise (WBE) both are the promising forms of balance training.
- Trial name
- NCT07150364
- Testing
- Square Stepping Exercise, Wobble Board Exercise
- Where
- Pakistan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Sarcopenia in Elderly, Falls
Prevalence of Sarcopenia-Promoting Medicines in Patients With Sarcopenia and Falls
Sarcopenia, characterised by the loss of muscle mass and function, is a common condition among the elderly and is often associated with increased risk of falls.
- Trial name
- NCT07127692
- Testing
- Strength, Assistance with walking, Rise from a chair, Climb stairs, and Falls (SARC-F) questionnaire, Hand grip strength, Timed Up and Go test
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Medway NHS Foundation Trust
Healthy Subjects (HS)
Self-initiated Perturbation-based Training in Older Adults
This is a single-blinded study. Participants will be randomly assigned to self-initiated perturbation-based balance training (SePBT) group or control (conventional balance training) group.
- Trial name
- NCT06774833
- Testing
- Self-initiated perturbation-based balance training, Conventional balance training
- Where
- Hong Kong
- Volunteers
- 48 people
- Sponsor
- The Hong Kong Polytechnic University
Falling, Community Dwelling Older Adults
Neurophysiological Changes After Perturbation-based Training in Older Adults
This is an assessor-blinded neurophysiological study. Participants will be randomly assigned to a perturbation-based training (PBT) or a walking (control) group.
- Conditions
- Falling, Community Dwelling Older Adults, Postural Stability, Brain Connectivity
- Trial name
- NCT06573658
- Testing
- Perturbation-based balance training (PBT), Walking exercise (control)
- Where
- Hong Kong
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Sarcopenia, Sarcopenia in Elderly
The Effect of Volunteer-Engaged Lifestyle Optimisation Via ICOPE on Sarcopenia in Older Adults (VELO-S)
Sarcopenia prevention and management are highly prioritised goals in the Healthy Ageing agenda. The study aims to: 1) evaluate the effects of the digital-enhanced, volunteer-engaged collaborative care pathway to improve…
- Conditions
- Sarcopenia, Sarcopenia in Elderly, Fall Prevention in Healthy Aging, Frailty Syndrome
- Trial name
- NCT07345832
- Testing
- Volunteer-Engaged Lifestyle Optimisation via ICOPE for Sarcopenia program (VELO-S), Attention control
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Stroke
Interoception in Stroke
This study aims to examine the associations of interoceptive awareness and interoceptive accuracy with plantar superficial sensory threshold, knee joint proprioception, pain intensity, and dynamic balance performance in…
- Trial name
- NCT07669246
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istinye University
Hypertension, Fall Risk
Short-Term Effects of Antihypertensive Drugs on Postural Balance and Fall Risk
The goal of this clinical trial is to compare the short-term effects of three commonly prescribed antihypertensive drug classes (beta-blockers, ACE inhibitors, and calcium channel blockers) on postural balance and fall risk in…
- Conditions
- Hypertension, Fall Risk, Postural Balance, Fear of Falling
- Trial name
- NCT07099677
- Testing
- Beta Blocker, ACE inhibitor, Calcium channel blocker
- Where
- Turkey (Türkiye)
- Volunteers
- 186 people
- Sponsor
- Abant Izzet Baysal University
Fall Prevention in Healthy Aging, Fall
Effect of LiFE-SePBT on Postural Stability in Community-dwelling Older Adults: an Assessor-blinded Randomised Controlled Trial
This study is an assessor-blinded randomised controlled trial investigating the effects of combined Lifestyle-integrated Functional Exercise and Self-initiated Perturbation-based Balance Training (LiFE-SePBT) on postural…
- Conditions
- Fall Prevention in Healthy Aging, Fall, Fall Prevention Training, Postural Control
- Trial name
- LiFE-SePBT (NCT07842094)
- Testing
- Lifestyle-integrated Functional Exercise, Upper limb mobilisation and flexibility training
- Where
- Hong Kong
- Volunteers
- 44 people
- Sponsor
- The Hong Kong Polytechnic University
Accidental Fall
Virtual Tai ji Quan Exercise to Prevent Falls in Older Adults
To examine two different exercise programs in reducing incidence of falls among community-dwelling older adults
- Trial name
- NCT05822466
- Testing
- Virtual tai ji quan: moving for better balance intervention (V-TJQMBB), Virtual multimodal exercise intervention (V-Multimodal)
- Where
- United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute