Clinical trials: Family History of Alcoholism
Alcoholism
Ketamine/Placebo Family History Positive Study
The proposed study is the first to explore the contribution of brain glutamate systems, a major target of ethanol in the brain, to the vulnerability to develop alcoholism.
- Trial name
- NCT00588952
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcoholic Intoxication, Neurobehavioral Manifestations
Residual Effects of Intoxication on Student Performance
The primary goal of the study is to assess the residual effects of heavy drinking on academic performance. The investigators will also explore whether these effects differ by family history of alcohol abuse and hangover symptoms…
- Trial name
- NCT00183170
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Boston University
Alcoholism
GABA Mechanisms Underlying the Vulnerability to Alcohol Dependence
This Project will explore the hypothesis that individuals with a family history positive for alcohol dependence (without any current Axis I disorder, except nicotine dependence), experience an alteration in the reward "valence"…
- Trial name
- NCT00611767
- Testing
- Thiopental
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcoholism
Intravenous Alcohol Administration Using BrAc Method in Healthy Subjects With and Without a Family History of Alcoholism
The proposed study is the first to explore the contribution of brain glutamate systems, a major target of ethanol in the brain, to the vulnerability to develop alcoholism.
- Trial name
- NCT00612352
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Yale University
Healthy
Functional Neuroimaging of Alcoholism Vulnerability (PIT)
This project compares Family History Positive (FHP) for alcoholism subjects to matched Family History Negative (FHN) subjects derived from the project Principal Investigator's National Institute on Alcohol Abuse and…
- Trial name
- CTNA (NCT01585168)
- Testing
- Memantine
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Yale University
Effects of Family History of Alcoholism and Sex on Alcohol Analgesia
Characterizing the Effects of Family History of Alcoholism on Alcohol Analgesia
Self-medication of pain with alcohol is a common, yet risky, behavior. Evidence suggests family history of alcoholism may affect the degree to which alcohol use relieves pain, but the independent contributions of expectation and…
- Trial name
- NCT04925076
- Testing
- Ethanol
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Florida
Alcoholism
High Dose Vitamin B1 to Reduce Abusive Alcohol Use
B1AS tests the hypothesis that increased vitamin B1 (thiamine) intake can repair brain systems damaged by alcohol and help people with alcohol problems control their alcohol use.
- Trial name
- B1AS (NCT00680121)
- Testing
- Benfotiamine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Kansas