Clinical trials: Family Medicine
General Practitioners
Placebo Interventions in General Practice
Physicians often have an ambivalent relationship to placebo interventions. On the one hand they know of the intriguing effect of sugar pills or saline infusions but on the other hand they mostly feel constrained to adopt…
- Trial name
- NCT00603928
- Where
- Switzerland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Chronic Disorders
Effectiveness of Community-Based Physiotherapy Versus General Practice
Summary: (Objectives and methodology of the project) AIM: To evaluate the clinical effectiveness of Community physiotherapy intervention on chronic diseases (heart disease, chronic obstructive pulmonary disease, back pain…
- Trial name
- ECACOM (NCT01172483)
- Testing
- general practice in primary care and education, Multimodal community program
- Where
- Spain
- Volunteers
- 220 people
- Sponsor
- University of Malaga
Essential Hypertension, Sleep Quality
Sleep Hygiene Education and Blood Pressure Control in Essential Hypertension in Primary Care
This randomized controlled trial evaluated the effect of a brief sleep hygiene education program on sleep quality and blood pressure in adults with essential hypertension attending a family practice center in southern Türkiye.
- Conditions
- Essential Hypertension, Sleep Quality, Primary Care
- Trial name
- NCT07257237
- Testing
- Sleep hygiene education program
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people
- Sponsor
- Ozturk Gurer Tutu, MD
Cancer, Breast, Cancer, Ovarian
Family History App in Personalized Medicine
A complete family history (FH) may identify persons at high risk for certain conditions. They can be offered genetic testing and life-saving screening and treatment.
- Conditions
- Cancer, Breast, Cancer, Ovarian, Cancer, Colorectal, Cancer, Prostate
- Trial name
- FHAMe (NCT04726319)
- Testing
- FHAMe Intervention
- Where
- Canada
- Volunteers
- 627 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hypercholesterolemia, Familial, Hypercholesterolemia, Familial, 1
Genetic Testing and Motivational Counseling for FH
To date, there are highly effective lipid-lowering drugs, the combination of which makes it possible to achieve the target level of LDL-C in most patients with familial hypercholesterolemia (FH).
- Conditions
- Hypercholesterolemia, Familial, Hypercholesterolemia, Familial, 1, Hypercholesterolemia, Familial, 2, Hypercholesterolemia, Familial, 3
- Trial name
- GENMOTIV-FH (NCT04656028)
- Testing
- Genetic Testing, Motivational Counseling, Lipid analysis
- Where
- Russia
- Volunteers
- 180 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
COPD
Implementation of an Evidence Based Smoking Cessation Strategy (SMOCC) for Patients With COPD in Primary Care
A controlled study demonstrated that a smoking cessation protocol in routine primary care, specifically targeted at patients with COPD (SMOCC), doubled the quit rates.
- Trial name
- NCT00294905
- Testing
- Implementation of a combined smoking cessation strategy
- Where
- Netherlands
- Volunteers
- 2,700 people
- Sponsor
- Radboud University Medical Center
Myocardial Infarction
Comparison of Information Recorded in MINAP, GPRD and HES: a CALIBER Study
Medical information is increasingly processed electronically. This study will describe the similarities and differences in the data recorded by different databases of electronic healthcare database.
- Trial name
- NCT01569139
- Where
- 3 sites in United Kingdom
- Volunteers
- 21,000 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Indication for ElectroCardioGram
Electrocardiogram in General Practice : the EGG Study
Existing resources to assist interpretation of ElectroCardioGram (ECG) in general practice provide specialized and comprehensive reading based on pathologies and ElectroCardioGram (ECG) signs rather than ElectroCardioGram (ECG)…
- Trial name
- EGG (NCT04241757)
- Testing
- ElectroCardioGram (ECG)
- Where
- France
- Volunteers
- 888 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Parent-Child Relations, Child Development
FamilieTrivsel i Almen Praksis: a Mentalisation Programme for Families With Young Children
This cluster randomised trial aims to establish the effectiveness of an online intervention designed to improve the ability of parents to 'mentalise' - in other words to understand their own mental states and that of others…
- Conditions
- Parent-Child Relations, Child Development, Parenting
- Trial name
- NCT04129359
- Testing
- FamilieTrivsel, enhanced care as usual
- Where
- Denmark
- Volunteers
- 624 people, healthy volunteers welcome
- Sponsor
- Research Unit Of General Practice, Copenhagen
Dysautonomia, Familial, Baroreflex Failure Syndrome
Carbidopa for the Treatment of Excessive Blood Pressure Variability
The overall study objectives are to determine whether carbidopa (Lodosyn®) is safe and well tolerated and to assess whether it can inhibit catecholamine-induced paroxysmal hypertension and normalize or reduce the exaggerated…
- Trial name
- CarbiFD (NCT02553265)
- Testing
- Carbidopa Low-Dose, Carbidopa High-Dose
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- NYU Langone Health
Papilloma Viral Infection
HPV and Male Homosexuality in General Practice?
The main objective of this study is to find out whether young MSM (men who have sex with men) believe it is important for their GP to be informed of their sexual orientation, in order to improve their clinical, especially with…
- Trial name
- HPV (NCT05078554)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Strasbourg, France
General Practice
Subjects Perceived as Embarrassing During a Consultation in General Medical Practice
Optimal medical care requires transparency and honesty. However, it is not always easy to address some issues that may be considered too personal, intimate or taboo, such as mental health, sexuality, addiction and death.
- Trial name
- Gene-MG (NCT06130605)
- Testing
- Data collection
- Where
- 2 sites in France
- Volunteers
- 2,000 people
- Sponsor
- Université de Reims Champagne-Ardenne
Childhood Asthma
Asthma Link Effectiveness Trial
The goal of this cluster Randomized Control Trial is to determine the effectiveness of Asthma Link, a school supervised asthma therapy program, compared with an educational asthma workbook, in improving asthma symptoms for…
- Trial name
- NCT06388460
- Testing
- Asthma Link, Enhanced Usual Care
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- University of Massachusetts, Worcester
Urinary Tract Infections
Reducing Antibiotic Use for Uncomplicated Urinary Tract Infection in General Practice by Treatment With Uva Ursi (UU)- a Comparative Effectiveness Trial
It is well known that "over-treatment" of straightforward infections should be avoided as far as possible. Evidence-based data on non antibiotic treatment options for common conditions are therefore needed urgently.
- Trial name
- REGATTA (NCT03151603)
- Testing
- Arctuvan, Fosfomycin
- Where
- 47 sites in Germany
- Volunteers
- 398 people
- Sponsor
- University Medical Center Goettingen
Cardiovascular Risk, Depression, Unipolar
LIVES: Personalized Lifestyle Intervention for Patients With Depression
Persons with affective disorder have a considerably increased risk of cardiovascular disease. To a considerable extent, this is due to an unhealthy life style.
- Conditions
- Cardiovascular Risk, Depression, Unipolar, Depression, Bipolar
- Trial name
- LIVES (NCT05767073)
- Testing
- Lifestyle InterVEntion (LIVE)
- Where
- 2 sites in Netherlands
- Volunteers
- 38 people
- Sponsor
- University Medical Center Groningen
Frail Elderly Syndrome, Chronic Disease
Implementing Advance Care Planning Conversation Tools in Family Practice
This study evaluates the use of advance care planning conversation tools with patients attending their family doctor's office. Patients complete tools about their values and wishes, and a health care provider uses a structured…
- Trial name
- NCT03508557
- Testing
- Advance care planning tools
- Where
- 4 sites in Canada
- Volunteers
- 80 people
- Sponsor
- McMaster University
Type 2 Diabetes Mellitus, Behavior
Ready to Act - Health Education in People With Hyperglycaemia
A pre-randomized study in primary health care was designed to investigate health education in a subpopulation extracted from general practitioners (GPs) in one Danish county in the treatment arm of the ADDITION…
- Trial name
- NCT01945645
- Testing
- Ready to act
- Where
- Denmark
- Volunteers
- 509 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pulmonary Arterial Hypertension
Hemodynamic Evaluation of Dose-response and Safety of Dry Powder Inhalation of Treprostinil
Acute and chronic hemodynamic dose-response and safety evaluation of LIQ861 in PAH subjects.
- Trial name
- NCT03884465
- Testing
- Inhaled dry powder treprostinil (LIQ861)
- Where
- 3 sites in France, Germany
- Volunteers
- 15 people
- Sponsor
- Liquidia Technologies, Inc.
Sexual Risk Behavior, Drug Use
eHealth Evidence-based Intervention (EBI) for Latino Youth in Primary Care
The purpose of this study is to test the relative effectiveness of a Hispanic-specific eHealth intervention, "e-Health Familias Unidas," in preventing and reducing drug use, sexual risk behaviors, and STIs among Hispanic youth in…
- Conditions
- Sexual Risk Behavior, Drug Use, Family Functioning
- Trial name
- NCT03009539
- Testing
- eHealth Familias Unidas Primary Care
- Where
- 12 sites in United States
- Volunteers
- 921 people, healthy volunteers welcome
- Sponsor
- University of Miami
End of Life, Support, Family
User Testing of an End of Life Medication Support Intervention for Lay Carers (Palliate).
The aim of this study is to evaluate the acceptability, safety and efficiency of the Palliate intervention. The Palliate intervention is a nurse-led process that includes training and documentation materials to support lay carers…
- Trial name
- NCT06526637
- Testing
- Paper Package, V1 + Preparation Sheet, V2 + Video Training
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Imperial College London