Clinical trials: Family Relationships
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy
This study will evaluate the efficacy and safety of vutrisiran 25 mg administered subcutaneously (SC) once every 3 months (q3M) compared to placebo in participants with ATTR amyloidosis with cardiomyopathy.
- Trial name
- NCT04153149
- Testing
- Vutrisiran, Sterile Normal Saline (0.9% NaCl)
- Where
- 119 sites in United States, Argentina and 30 more
- Volunteers
- 655 people
- Sponsor
- Alnylam Pharmaceuticals
Alcohol Drinking, Alcohol Intoxication
Family Based Prevention of Alcohol and Risky Sex for Older Teens
An online, interactive web-based program for older teens and their parents is designed to address teen alcohol use and teen relationships.
- Conditions
- Alcohol Drinking, Alcohol Intoxication, Alcohol Poison, Alcohol-Related Disorders
- Trial name
- NCT03521115
- Testing
- Smart Choices 4 Teens
- Where
- United States
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Second Hand Tobacco Smoke, Nicotine Dependence
Kids Safe and Smokefree (KiSS)
The study's primary aim is to test the hypothesis that an intervention integrating pediatric clinic-level quality improvement with home-level behavioral counseling (CQI+BC) will result in greater reductions in child cotinine (a…
- Trial name
- KiSS (NCT01745393)
- Testing
- Clinic Quality Improvement + Behavioral Counseling, Clinic Quality Improvement + Attention Control
- Where
- 4 sites in United States
- Volunteers
- 327 people
- Sponsor
- Temple University
Family Mindfulness-based Intervention in War-affected Families, Intergenerational Trauma
FMBI With War-affected Families
This study has two central research questions: 1) Is implementing a family mindfulness-based intervention with war-affected immigrant families through community based participatory research methods feasible?; and 2) Does the…
- Conditions
- Family Mindfulness-based Intervention in War-affected Families, Intergenerational Trauma, War-Related Trauma
- Trial name
- NCT05241314
- Testing
- Learning to BREATHE, After Deployment Adaptive Parenting Tools (ADAPT)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Posttraumatic Neuroses
An Adjunctive Family Intervention for Individual Posttraumatic Stress Disorder Treatment
This study aims to test a brief family intervention (the BFI) to enhance individually-delivered PTSD treatment for Veterans.
- Trial name
- NCT02956434
- Testing
- Brief Family Intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- VA Office of Research and Development
Pediatric Obesity, Risk Reduction Behavior
FirstStep2Health Intervention
This project will determine the preliminary efficacy of an innovative intergenerational intervention among Head Start preschoolers, aged 3-5 years, and their caregivers.
- Conditions
- Pediatric Obesity, Risk Reduction Behavior, Early Intervention, Intergenerational Relations
- Trial name
- NCT04164277
- Testing
- Caregiver Component., Caregiver-Preschooler Learning., Center-based Preschooler Component.
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Community Reinforcement And Family Training, Family Health
Scalable Digital Delivery of Evidence-based Training for Professionals to Maximize Treatment Rates of OUD in Families
The goal of this project is to develop and evaluate the technical feasibility and commercial viability of a scalable digital counselor training program for CRAFT.
- Conditions
- Community Reinforcement And Family Training, Family Health, Substance-Related Disorders
- Trial name
- NCT05875142
- Testing
- Behavioral: Digital Tutorial Overview, Behavioral: Training Materials, Behavioral: Feedback and Coaching
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- We The Village, Inc.
Father - Child Relations
The Dedicated African American Dad Study
The number of children living apart from their fathers has grown nationally, and the greatest percentage is evident among African American (AA) families; two-thirds of all African American children live in households without…
- Trial name
- DAAD (NCT02412748)
- Testing
- BBTF Intervention, Financial Literacy Program
- Where
- United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Postintensive Care Syndrome, Family Members
Family Support Intervention in Intensive Care Units
Background: Family members of critically ill patients face considerable uncertainty and distress during their close other's intensive care unit (ICU) stay, with about 20-60% of family members experiencing post-traumatic distress…
- Conditions
- Postintensive Care Syndrome, Family Members, Quality of Life, Depression, Anxiety
- Trial name
- FICUS (NCT05280691)
- Testing
- Family Support Intervention (FSI)
- Where
- 12 sites in Switzerland
- Volunteers
- 885 people
- Sponsor
- Rahel Naef
Fetal Alcohol Spectrum Disorders
Trial of the Families Moving Forward (FMF) Connect Mobile Health Intervention
The purpose of this study is to test a new smartphone "app" for parents/caregivers of children with fetal alcohol spectrum disorder (FASD). The app is called Families Moving Forward (FMF) Connect.
- Trial name
- NCT04194489
- Testing
- FMF Connect
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- University of Rochester
PTSD, Alcohol Abuse
Helping Families Help Veterans With PTSD and Alcohol Abuse: An RCT of VA-CRAFT
This project begins to evaluate the effectiveness of a web-based family outreach tool that is designed to promote treatment engagement among Veterans with posttraumatic stress disorder (PTSD) or alcohol use disorders (AUDs) but…
- Trial name
- NCT01678196
- Testing
- VA-CRAFT, Control
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- VA Office of Research and Development
Alcohol Use Disorder
Brief Family-involved Treatment for Alcohol Use Disorder
Family-involved treatments for alcohol use disorders (AUDs) hold considerable promise to improve engagement and compliance with treatment and improve treatment outcomes.
- Trial name
- B-FIT (NCT05545644)
- Testing
- Brief Family-Involved Treatment for Alcohol Use Disorder
- Volunteers
- 35 people
- Sponsor
- University of New Mexico
Cardiac Arrest, Post Traumatic Stress Syndrome
Family-Authored ICU Diaries to Reduce Fear in Patients Experiencing a Cardiac Arrest (FAID Fear)
The present study will: Aim 1: Enroll 15 family members of CA patients to (a) pilot recruitment procedures, (b) estimate retention, and (c) assess acceptability of study procedures.
- Trial name
- FAID Fear (NCT05144477)
- Testing
- FAID Fear Intervention
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Columbia University
Alcoholism
Ketamine/Placebo Family History Positive Study
The proposed study is the first to explore the contribution of brain glutamate systems, a major target of ethanol in the brain, to the vulnerability to develop alcoholism.
- Trial name
- NCT00588952
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Yale University
Neoplasms, Cancer
The Families Addressing Cancer Together Intervention for Parents With Cancer
The proposed pilot randomized controlled trial will test the FACT (Families Addressing Cancer Together) intervention designed to improve parents' confidence and ability to talk about their cancer with their minor children.
- Conditions
- Neoplasms, Cancer, Parenting, Communication
- Trial name
- FACT (NCT05377749)
- Testing
- FACT
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Self Harm, Depression
Computer Assisted Family Intervention to Treat Self-Harm Disparities in Latinas and Sexual/Gender Minority Youth
This study is designed to refine and test the efficacy of a computer assisted culturally informed and flexible/adaptive intervention for Latino adolescents for whom self-harm behaviors are a health disparity-specifically, Latinas…
- Conditions
- Self Harm, Depression, Emotion Dysregulation, Suicidal Ideation
- Trial name
- NCT03709472
- Testing
- Computer Assisted CIFFTA, Behavioral: Traditional face-to-face treatment-no technology
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- University of Miami
Community Reinforcement And Family Training, Family Health
We The Village Family Support Study
The United States is in the midst of an opioid crisis. Over-prescription of opioid analgesic pain relievers contributed to a rapid escalation of use and misuse of these substances across the country.
- Conditions
- Community Reinforcement And Family Training, Family Health, Substance-Related Disorders
- Trial name
- NCT04250077
- Testing
- Community Reinforcement And Family Training (CRAFT), We The Village Peer Community Forum
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- We The Village, Inc.
Cardiac Arrest
Removing Surrogates' Uncertainty to Reduce Fear and Anxiety After Cardiac Events
The goal of this study is to test the feasibility and acceptability of an informational website to reduce uncertainty, psychological distress, and caregiver burden among close family members of cardiac arrest patients.
- Trial name
- RESURFACE (NCT06048068)
- Testing
- Educational Informational Platform
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Columbia University
Substance Use
Individual and Family Motivational Interviews for Substance Using Truant Teens
This application will provide a test of one potential model for adding substance use assessment and brief intervention into a truancy court program.
- Trial name
- NCT01170026
- Testing
- Family Check-up/ Individual MI, Individual and family psychoeducation
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Brown University
Psychosocial Deprivation, Work-Related Stress
Family Supportive Supervisor Training and Workplace Assessment Tool
This study will evaluate the effectiveness of FSST 2.0 (family supportive supervisor training plus support for use of family and sick leaves) using a randomized control trial design.
- Conditions
- Psychosocial Deprivation, Work-Related Stress, Life-work Imbalance
- Trial name
- FSST (NCT05080426)
- Testing
- Family Supportive Supervisor Training 2.0
- Where
- United States
- Volunteers
- 1,175 people, healthy volunteers welcome
- Sponsor
- Work Life Help