Clinical trials: Fast Track, open to volunteers
Cardiac Surgery
Ultra Fast-Track vs Fast-Track Protocols in Off-Pump and Minimally Invasive Valve Cardiac Surgery
Fast-track cardiac anesthesia (FTCA) has gained significant popularity over the past decades due to its potential to reduce healthcare costs and optimize the use of medical resources.
- Trial name
- Fast Track (NCT07518524)
- Testing
- Fast Track Cardiac Anesthesia (FTCA), Ultra Fast Track Cardiac Anesthesia (UFTCA)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Azienda Socio Sanitaria Territoriale Ovest Milanese, Ospedale di Legnano
Valve Disease, Heart, CABG
Nonintubated Anesthesia for Adult Cardiac Surgery With Cardiopulmonary Bypass
The goal of this prospective, multicenter, randomized clinical trial is to learn whether a nonintubated supraglottic airway anesthesia strategy with early restoration of spontaneous breathing can reduce postoperative pulmonary…
- Trial name
- NIA-Heart (NCT07744009)
- Testing
- Nonintubated Anesthesia Group, Conventional Anesthesia Group
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Osteoarthritis, Knee, Arthropathy of Knee
Total Knee Arthroplasty: Fast Track Protocol is the Future?
Fast-track total knee arthroplasty (TKA) is a well-established concept including optimized logistics and evidence-based treatment, focusing on minimizing surgical stress and improved post-operative recovery.
- Trial name
- FastTrack-G (NCT03869996)
- Testing
- fast track care protocol, standard care protocol
- Where
- Italy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Mechanical Ventilation, Cardiac Surgery
Planned Operating-Room Extubation After Cardiac Surgery
The goal of this clinical trial is to learn whether removing the breathing tube in the operating room after cardiac surgery helps adults recover faster than removing the breathing tube later in the intensive care unit (ICU)…
- Conditions
- Mechanical Ventilation, Cardiac Surgery, Fast Track Program,(Enhanced Recovery After Surgery (ERAS))
- Trial name
- NCT07874607
- Testing
- Planned Operating-Room Extubation, Standard Early ICU Extubation
- Where
- 2 sites in Canada
- Volunteers
- 336 people
- Sponsor
- Nova Scotia Health Authority
Coxarthrosis
Comparison of Complication Rate, Functional Outcome and Quality of Life Between Standard Therapy Versus Fast-track Therapy in Patients Following Hip Replacement Surgery
The fast track group vs. control group will be compared with regard to hospitalization time and the non-inferiority of the fast track group vs. control group with regard to HOOS will be assessed.
- Trial name
- NCT07199751
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Technical University of Munich
Laparoscopic Appendectomy, Complicated Appendicitis
Fast Track Therapeutic Model in Acute Complicated Appendicitis in Pediatrics
To evaluate whether a postoperative therapeutic strategy, Fast Track, aimed at shortening hospital stay in pediatric patients undergoing laparoscopic appendectomy for complicated acute appendicitis, yields outcomes that are not…
- Conditions
- Laparoscopic Appendectomy, Complicated Appendicitis, Periappendicular Abscess
- Trial name
- FTAA (NCT05761080)
- Testing
- Oral amoxicillin-clavulanic acid (40mg/kg in 3 times/day; maximum dose 3g/day), Inpatient postpoperative intravenous antibiotic treatment according to the established protocol in each center
- Where
- 12 sites in Spain
- Volunteers
- 772 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Abdominal Aortic Aneurysm, Infrarenal Abdominal Aortic Aneurysm
Fast-Track Protocol for Endovascular Aneurysm Repair (EVAR) of Infrarenal Abdominal Aortic Aneurysms
The study aims to evaluate the clinical and economic efficacy of a "Fast-Track" protocol for the elective endovascular treatment (EVAR) of infrarenal abdominal aortic aneurysms (AAA).
- Conditions
- Abdominal Aortic Aneurysm, Infrarenal Abdominal Aortic Aneurysm, Penetrating Aortic Ulcers (PAUs), Iliac Aneurysm
- Trial name
- NCT07431047
- Volunteers
- 50 people
- Sponsor
- University of Bologna
Supratentorial Brain Tumor Surgery
FASt Track in Elective Neurosurgery: the Role of Low Propofol Bis-NOL Guided General Anaesthesia for Full, Early and Safe Awakening
To evaluate the effect of intraoperative sedation dosage on awakening and recovery of consciousness after elective neurosurgical surgery.
- Trial name
- FasTrack (NCT06844838)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Knee Osteoarthritis, Knee Pain Chronic
The Effect of RF Genicular Nerve Block Applied in the Preoperative Period on Fast-track Total Knee Arthroplasty
In our study, investigators plan to compare the preoperative RF and genicular nerve ablation approach in patients who underwent TKA(Total Knee Arthroplasty) using the Fast-Track protocol in terms of meeting postoperative pain…
- Trial name
- NCT06239649
- Testing
- Genicular nerve Radiofrequency Ablation block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Pamukkale University
Multivessel Coronary Artery Disease
Insights From the FAST-TRACK CABG Trial: a Clinical Outcome Study in Patient With Previous Surgical Revascularization for Complex Three-vessel or Left Main Coronary Artery Disease Based on Coronary Computed Tomography Angiogram, and Fractional Flow Reserve Derived by Computed Tomography
Coronary computed tomography angiography (CCTA) is a non-invasive imaging tool that characterizes coronary artery anatomy and provides detailed assessments of plaque morphology, composition , inflammation, and hemodynamics, which…
- Trial name
- FAST-CABG (NCT07628270)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Centro Cardiologico Monzino
Osteo Arthritis Knee, Insomnia
Improving Sleep After TKA Using Mirtazapine and Quetiapine
Use of mirtazapine and quetiapine for improvement of sleep quality after TKA
- Trial name
- NCT04728581
- Testing
- Mirtazapine, Quetiapine
- Where
- 2 sites in Netherlands
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- St. Anna Ziekenhuis, Geldrop, Netherlands
Emergency Department, Non-specific Complaints
The Safe Fast Track Study
Emergency departments (ED) internationally are treating an increasing number of patients. Most require hospital services but some could be better cared for on alternative pathways. D-dimer has some unique properties.
- Trial name
- SafeFT (NCT06219486)
- Testing
- D-dimer
- Where
- 2 sites in Denmark
- Volunteers
- 1,538 people
- Sponsor
- Odense University Hospital
Postoperative Pain, Postoperative Complications
Protocol for Accelerated Recovery in Patients Undergoing Thoracic Surgical Procedures (PROSM). Study Randomized Comparative Between the Adoption of the Proposed Guidelines and the Traditional Method Currently Used in the Institution
Introduction: Aiming at reducing costs and optimizing the use of these financial resources, several postoperative recovery protocols have emerged that aim to reduce the length of hospital stay by accelerating surgical…
- Conditions
- Postoperative Pain, Postoperative Complications, Postoperative Nausea, Lung Cancer
- Trial name
- PROSM (NCT03271749)
- Testing
- PROSM guidelines for preoperative, anesthesia and postoperative care for lung resections
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Igor Renato Louro Bruno de Abreu
Postoperative Cognitive Dysfunction (POCD), Cognitive Change
Early Cognitive Changes After Same-day Discharge Hip and Knee Arthroplasty
The goal of this observational study is to explore early cognitive changes in patients aged 70 years or older undergoing same-day discharge after hip or knee replacement surgery.
- Conditions
- Postoperative Cognitive Dysfunction (POCD), Cognitive Change, Total Knee Arthroplasty, Unicompartmental Knee Arthroplasty
- Trial name
- NCT07598552
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Odense University Hospital
Heart Valve Diseases, Enhanced Recovery After Surgery
Multicentre Clinical Study of Ultra-Fast-Track Anaesthesia for Minimally Invasive Heart Valve Surgery
The goal of this clinical trial is to evaluate the clinical effects of ultra-fast-track anesthesia (UFTA) for minimally invasive cardiac surgery (MICS) in adults.
- Trial name
- NCT06541483
- Testing
- Ultra-Fast-Track Cardiac Anesthesia(UFTCA), conventional general anesthesia (CGA)
- Volunteers
- 1,200 people
- Sponsor
- Zhejiang Provincial People's Hospital
Cancer, Immune Checkpoint Inhibitor
Fast-Track Cardiovascular Assessment for Suspicion of Cardiovascular Events on Immunecheckpoint Inhibitors
Prospective study cohort on patients addressed for suspected cardiovascular event on immune checkpoint inchibitors. Longitudinal prospective single center cohort.
- Conditions
- Cancer, Immune Checkpoint Inhibitor, Cardiovascular Complication, Immune-related Adverse Event
- Trial name
- FAST-TRACK (NCT05799898)
- Testing
- No intervention for research purposes only
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Institut Mutualiste Montsouris
Hip Arthroplasty, Total, Prevention of Venous Thromboembolism
ENhanced Recovery and ABbreviated LEngth of Anticoagulation for Thromboprophylaxis After Primary Hip Arthroplasty
Surgical hip replacement (total hip arthroplasty, THA) is associated with a high risk of venous thromboembolism, but the appropriate duration of postoperative medical thromboprophylaxis ("anticoagulation") remains highly…
- Trial name
- ENABLE-Hip (NCT06611319)
- Testing
- Prevention of Venous Thromboembolism
- Where
- 6 sites in Austria, Germany
- Volunteers
- 2,932 people
- Sponsor
- Prof. Stavros Konstantinides, MD
Giant Cell Arteritis (GCA)
Performance of a Fast-track Pathway for Giant Cell Arteritis Diagnosis
Giant cell arteritis is a vasculitis, i.e. inflammation of the artery walls, which generally affects people over the age of 50. Diagnosis can be long and difficult, as the clinical signs are not specific (headache, pain in the…
- Trial name
- QuickDx-GCA (NCT06742671)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Cardiac Disease Minimally Invasive Cardiac Surgery Postoperative Pain
Fast-Track Anesthesia in Minimally Invasive Cardiac Surgery: Dexmedetomidine and Erector Spinae Plane Block vs Opioid-Based Anesthesia
Enhanced Recovery After Surgery (ERAS) protocols have revolutionized perioperative management by implementing evidence-based, patient-centered strategies that improve clinical outcomes, shorten hospital length of stay, and reduce…
- Trial name
- Esp (NCT07749274)
- Testing
- Dexmedetomidine, Ultrasound-Guided Bilateral Erector Spinae Plane Block (ESPB), Fentanyl
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University