Clinical trials: Fat Loss
Obesity
Effect of Tirzepatide on Brown Adipose Tissue in Obesity
This study is testing whether a new anti-obesity medicine called tirzepatide can increase the activity of special fat cells in the body that help burn energy. These fat cells are known as brown and beige fat.
- Trial name
- TABFAT (NCT06893211)
- Testing
- Tirzepatide
- Where
- Slovenia
- Volunteers
- 34 people
- Sponsor
- University Medical Centre Ljubljana
Obesity, Exercise Training
Comparison of Two Different Intensity Exercises on Young Women With Obesity
Obesity is one of the most common preventable public health problems. Diet regulation and exercise practices are the most commonly used methods in reducing fat tissue.
- Trial name
- NCT06610955
- Testing
- High intensity interval training, Moderate intensity continuous training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ahi Evran University Education and Research Hospital
Obesity, Liver Diseases
Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease globally. While weight loss through lifestyle modification is the standard treatment, most patients regain weight limiting…
- Conditions
- Obesity, Liver Diseases, Liver Fibrosis, Liver Fat
- Trial name
- NCT06138821
- Testing
- ESG + lifestyle modification, Lifestyle modification
- Where
- 2 sites in United States
- Volunteers
- 132 people
- Sponsor
- Pichamol Jirapinyo, MD, MPH
NAFLD
Effects of Overfeeding Followed by Weight Loss on Liver Fat Content and Adipose Tissue Inflammation
A. BACKGROUND Accumulation of fat in the liver due to non-alcoholic causes (NAFLD) is associated with hepatic insulin resistance, which impairs the ability of insulin to inhibit the production of glucose and VLDL .
- Trial name
- NCT02133144
- Testing
- overeating fat, overeating carbohydrate
- Where
- Finland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Pancreatic Ductal Adenocarcinoma (PDAC), Hand Grip Strength
Using Strength Tests to Better Understand How Pancreatic Cancer Affects Muscle Mass and Quality of Life
The goal of this clinical trial is to measure hand grip strength in adults with pancreatic ductal adenocarcinoma (PDAC). The main questions it aims to answer are: Is it feasible to measure hand grip strength as part of a clinic…
- Trial name
- PanFit (NCT07255001)
- Testing
- Hand grip strength assessments using a dynamometer
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- British Columbia Cancer Agency
Obesity, Overweight and Obesity
Investigation of the Effects of a Bifidobacterium Breve Strain on Fat Loss in Healthy Adults
Overweight has become a critical issue in North America and the market value of weight loss products is expected to rise as the population becomes more health-conscious and aware of the risks associated with excess body weight.
- Trial name
- NCT04677738
- Testing
- B. breve strain
- Where
- Canada
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Morinaga Milk Industry Co., LTD
HIV Infections, Lipodystrophy
Observational Study of Fat Loss in HIV Infected Adults Taking Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
Nucleoside reverse transcriptase inhibitors (NRTIs) are a class of anti-HIV (Human Immunodeficiency Virus) drug that can be an important part of an HIV treatment regimen.
- Conditions
- HIV Infections, Lipodystrophy, Metabolic Diseases, Nutrition Disorders
- Trial name
- NCT00119405
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Obesity, Weight Loss
Low Fat Plant-based Diet Effects on Body Composition Indices
The effect of a diet free from animal-sourced nutrients on body composition in weight reduction programs is not well established.
- Trial name
- LFPBDS (NCT02906072)
- Testing
- Low fat plant-based diet, Lectures on health effects of a low fat plant-based diet.
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Barbara Jakše s.p.
Overweight
The Effect of a High Protein, High Fiber Dietary Supplement on Weight and Fat Loss
The objective of this study is to investigate the effect of a high protein, high fiber dietary supplement on weight and fat loss in healthy overweight adults.
- Trial name
- NCT03057873
- Testing
- High protein, high fiber dietary supplement
- Where
- 3 sites in United States, Canada
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Beachbody
Obesity, Overweight
Weight Regain After Consumption of Food Supplement and Interventional Diet Program
Effect of the dietary supplement (FAT-BINDER DAMM) on weight regain after 9 months of control weight program
- Conditions
- Obesity, Overweight, Weight Loss, Body Weight Changes
- Trial name
- fat-binder (NCT03554525)
- Testing
- Fat-binder damm
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Obesity
The Effects of Continuous vs. Intermittent Caloric Restriction on Fat Los
The purpose of this research study examines fat mass loss using a continuous calorie reduction protocol versus continuous caloric restriction interspersed with "diet refeeds" and "diet breaks" over 12 weeks.
- Trial name
- NCT06079658
- Testing
- Continuous Caloric Restriction versus Intermittent Caloric Restriction on Fat Loss
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Coastal Carolina University
Breast Cancer, Obesity
Nutritional Intervention-induced Weight Loss During the Oncological Treatment of Obesity-related Breast Cancer
Obesity could become the first evitable cause of breast cancer in the near future. Due to the relatively slow rate of development in this field, greater efforts must be applied in this area.
- Conditions
- Breast Cancer, Obesity, Weight Change, Body, Epigenetic Disorder
- Trial name
- NUTOBREST (NCT06046755)
- Testing
- Very low calorie ketogenic diet (VLCKD), Group educational intervention program (IGOBE)
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Hospital Clinico Universitario de Santiago
Obesity
Increased Dietary Protein and Meal Frequency Reduces Total and Abdominal Body Fat During Weight Maintenance and Weight Loss
The purpose of the current study was to examine the impact of macronutrient intake (PRO, 15% vs. 35%) and meal frequency (3 vs. 6 meals/day) on body composition, postprandial thermogenesis and plasma adipokines before and after…
- Trial name
- 3v6 (NCT01749449)
- Testing
- protein and meal frequency
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Obesity
Effects of Leptin Treatment on Weight Loss
This is a double blind placebo controlled clinical study designed to determine the effects of leptin on the changes that occur in the body during weight loss achieved by a very low calorie diet.
- Trial name
- NCT00050791
- Testing
- Leptin, Very Low Calorie Diet
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Overweight
The Effect of Small Wins on Body Fat Loss
This 24-week-long study compares the effectiveness of two finance incentive structures for weight loss: 1) smaller rewards for achieving intermediate goals vs 2) large reward for achieving an overall goal.
- Trial name
- NCT04973072
- Testing
- One large reward treatment, Small wins treatment
- Where
- Singapore
- Volunteers
- 600 people
- Sponsor
- Noah Lim
Obesity
Efficacy of D-allulose on Weight and Fat Loss and Insulin Resistance in Non-diabetic Obese Subjects
Prospective, randomized, double-blind, controlled-trial 30 subjects in each groups Group - I consume pure D-allulose 5 g 3 times a day before meal to right after meal (with any liquid) and Group - II control group with…
- Trial name
- NCT02988999
- Testing
- D-allulose, erythritol
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Obesity
Harmonic Versus Electro Surgery in Lower Body Lift Procedures
The objective of this study is to determine if the use of The Harmonic™ (an ultrasonic surgical instrument) in Lower Body Lift procedures reduces volume and duration of wound drainage after surgery when compared to Electro…
- Trial name
- LBL (NCT00522171)
- Testing
- The Harmonic™ ultrasonic scalpel
- Where
- 2 sites in United States, Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ethicon Endo-Surgery
Sport Nutrition, Probiotic
Supplementation With GKEX Sports Probiotic Combo for Muscle Gain and Fat Loss Assessment
Objective: To discuss the "GKEX Sports Probiotics Combination (hereinafter referred to as GKEX)", a product commissioned by Grape King Biotechnology Co., Ltd., and its effects on increasing muscle mass, muscle strength, physical…
- Trial name
- NCT05909475
- Testing
- GKEX
- Where
- Taiwan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Morbid Obesity
Treatment of Low Metabolic Rate Following Bariatric Surgery
Purpose is to determine the effect of ephedrine and caffeine, on metabolic rate and weight loss after bariatric surgery. Approximately 40% of patients struggle with their weight loss rate, or metabolic rate, after bariatric…
- Trial name
- NCT01596907
- Testing
- Ephedrine sulfate with caffeine, cellulose
- Where
- 2 sites in United States
- Volunteers
- 218 people
- Sponsor
- Oregon Weight Loss Surgery, LLC
Obesity & Overweight, Healthcare Worker
Personalized Nutrition Coaching for a Weight Loss Program Among Overweight and Obese Nurses
Obesity among healthcare workers has become an increasing public health concern, with potential consequences for work productivity, quality of care, and long-term health outcomes.
- Conditions
- Obesity & Overweight, Healthcare Worker, Low Physical Activity Level
- Trial name
- NCT07440979
- Testing
- Personalized Nutrition Coaching
- Where
- Indonesia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran