Clinical trials: Fat Mass
Gout, Hyperuricemia
The Diet Gout Trial
Unhealthy diet has long been associated with high uric acid levels and gout. The DASH diet may lower uric acid levels. This study will examine the effects of the DASH diet on uric acid in adults with a history of gout.
- Trial name
- DIGO (NCT03569020)
- Testing
- Subsidy for food purchases and dietitian education
- Where
- 2 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
HIV Seropositivity, Metabolic Syndrome
Effect on Liver Fat and Metabolic Parameters When Switching a Protease Inhibitor or Efavirenz to Raltegravir
This study will provide data on the switch from a protease inhibitor or efavirenz to the new formulation of raltegravir (RAL) dosed once daily.
- Conditions
- HIV Seropositivity, Metabolic Syndrome, Fatty Liver
- Trial name
- OBERAL (NCT03374358)
- Testing
- Raltegravir
- Where
- Finland
- Volunteers
- 45 people
- Sponsor
- Helsinki University Central Hospital
Unspecified Adult Solid Tumor, Protocol Specific, Weight Changes
Oxandrolone Compared With Megestrol in Preventing Weight Loss in Patients Receiving Chemotherapy for Cancer
RATIONALE: Oxandrolone and megestrol may help prevent weight loss and improve quality of life in patients with cancer. It is not yet known whether oxandrolone is more effective than megestrol in preventing weight loss and…
- Trial name
- NCT00070148
- Testing
- Megestrol Acetate, Oxandrolone 20 mg
- Where
- 20 sites in United States
- Volunteers
- 155 people
- Sponsor
- Wake Forest University Health Sciences
Neonates
Body Composition Assessment in Healthy Full-term Neonates by Anthropometry, Air Displacement Plethysmography and Multiple-frequency Bio-impedance Analysis
Low birth weight and prematurity are associated with adverse metabolic outcome in adult life. Yet it remains to be determined whether this outcome is the consequence of the low birth weight per se, or of the catch up growth…
- Trial name
- NCT00890344
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Menopause Related Conditions, Sarcopenia
Effects of Time-restricted Eating and Exercise Training on Skeletal Muscle Mass Quantity, Quality and Function in Postmenopausal Women With Overweight and Obesity
The goal of this randomized controlled trial] is to investigate the effects of a 12-week time restricted eating (TRE) and exercise combined intervention, as compared to (i) TRE alone, and to (ii) Caloric Restriction (CR) plus the…
- Conditions
- Menopause Related Conditions, Sarcopenia, Osteoporosis Postmenopausal, Obesity
- Trial name
- NCT05912309
- Testing
- Time Restricted Eating (TRE), Exercise, Caloric Restriction
- Where
- Spain
- Volunteers
- 78 people
- Sponsor
- Idoia Labayen
Body Composition, Physical Function
Lifestyle Intervention to Improve Muscle Function in Older Adults
The goal of this randomized controlled two-arm trial is to determine the effect of a diet and exercise intervention for 12 weeks on body composition, muscle function, and energy balance in 80 adults aged 50 years and over with…
- Conditions
- Body Composition, Physical Function, Energy Balance
- Trial name
- NCT07597980
- Testing
- Structured nutrition plan, Typical or usual diet, Supervised Exercise
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Pennington Biomedical Research Center
Breast Cancer
CDK and Body Composition Study
The goal of this study is to evaluate changes in body composition among patients who are treated with cyclin-dependent kinase (CDK) 4/6 inhibitors (abemaciclib, ribociclib, or palbociclib).
- Trial name
- NCT03697577
- Testing
- CT scans, DEXA scan
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Montefiore Medical Center
Overweight, Obesity
"Improving Diet, Exercise And Lifestyle (IDEAL) for Women" Study
Diets all share the same principle: eat less energy than you need. This results in weight loss. However, the weight loss is usually a combination of a loss of body fat and muscle mass.
- Trial name
- NCT00710398
- Testing
- Exercise - Aerobic and Resistance, Dietary - Caloric Restriction
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- McMaster University
Athlete, Relative Energy Deficiency in Sport
Preventing Athlete Under-fueling Through Nutrition.
The goal is to improve nutrition screening and support for Division III athletes. The study will use standard, low-risk nutrition screening methods, such as measuring height, weight, grip strength, and body composition, as well…
- Conditions
- Athlete, Relative Energy Deficiency in Sport, Low Energy Availability
- Trial name
- PERFORM (NCT07136038)
- Testing
- Low Energy Availability Screening and Nutrition Support
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Healthy Participants, Normal Weight Adults
Blood Glucose Levels After Bread Consumption Between Participants With Normal Weight and Overweight/Obesity
Obesity and increased blood glucose peaks are risk factors for type 2 diabetes mellitus (T2DM). Few studies have explored whether increased body fat contributes to higher blood glucose peaks after food consumption.
- Conditions
- Healthy Participants, Normal Weight Adults, Overweight or Obese Adults
- Trial name
- PPGRB (NCT07158762)
- Testing
- White bread, Wholemeal bread
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- City, University of London
Obesity
Testing the Gravitostat in Humans: the Impact of a Weighted Vest in Patients Post Bariatric Surgery on Fat-free Mass Retention and Weight Loss
The mechanisms regulating fat mass homeostasis are incompletely understood although recent animal and human trials would suggest that there is a leptin independent regulatory pathway which may play a role in weight control and…
- Trial name
- NCT04809129
- Testing
- Weighted vest
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Prostate Cancer
Phase IV Study to Evaluate Bone Mineral Density in No-bone Metastatic Prostate Cancer Treated With Degarelix
The aim of this phase IV interventional study is to evaluate variation in bone mineral density and lean and fat body composition in patients with prostate cancer without bone metastasis, treated with Degarelix.
- Trial name
- BLADE (NCT03202381)
- Testing
- Degarelix
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Obesity
Effects of Repeat Dosing of GSK1521498
The overall purpose of this study is to see whether the drug is safe and well tolerated when given to overweight or obese but otherwise healthy volunteers for 10 days.
- Trial name
- NCT00976105
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Body Composition
Effect of Cinnamon Powder Capsules on Body Composition
Obesity is a global health concern that significantly affects individuals, and its prevalence is still rising at an alarming rate. While various treatments are available, they often come with unwanted side effects.
- Trial name
- NCT06119555
- Testing
- Cinnamon Capsules
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Vagus Nerve Stimulation, Obesity
Auricular Vagus Stimulation in Obesity
Transcutaneous vagus nerve stimulation (TENS) involves stimulation of the left and/or right auricular branch of the vagus nerve with low-frequency electrical impulses.
- Trial name
- NCT05230628
- Testing
- Active TENS
- Where
- Russia
- Volunteers
- 131 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Overweight and Obesity
Body Fat Mass Association With Clinical Metabolic Profiles, Markers of Inflammation and Adipocytokines
Overweight and obesity have become an increasing problem in patients on hemodialysis. However, in virtually all observational studies in chronic kidney disease(CKD) and dialysis patients , using body mass index(BMI) as metric fat…
- Trial name
- NCT02799719
- Volunteers
- 65 people
- Sponsor
- Tungs' Taichung Metroharbour Hospital
Pancreatic Ductal Adenocarcinoma (PDAC), Hand Grip Strength
Using Strength Tests to Better Understand How Pancreatic Cancer Affects Muscle Mass and Quality of Life
The goal of this clinical trial is to measure hand grip strength in adults with pancreatic ductal adenocarcinoma (PDAC). The main questions it aims to answer are: Is it feasible to measure hand grip strength as part of a clinic…
- Trial name
- PanFit (NCT07255001)
- Testing
- Hand grip strength assessments using a dynamometer
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- British Columbia Cancer Agency
Obesity, Gastric Cancer
Effect of Obesity on Surgical Outcomes and Survival for Gastric Cancer
As the number of obesity continues to increase, surgical oncologist pay more attention to the effect of obesity on surgical outcomes and survival of digestive systemin cancers.
- Trial name
- NCT02800005
- Testing
- AFA group (successive patients), BMI group (successive patients)
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Jian-Kun Hu
Pancreas Cancer, Colorectal Cancer
The Relationship Between Fat Free Mass and Toxicity of Cytostatics in Cancer Patients
An observational study of the relationship between fat free mass and toxicity of cytostatics in cancer patients, at the department of Clinical Oncology at Zealand University Hospital, Roskilde, Denmark.
- Trial name
- NCT04528745
- Testing
- Bio Impedance Spectroscopy (BIS)
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- University of Copenhagen
Diabetes Mellitus, Type 2
Comparative Metabolomics in Diabetes Patients From Sri Lanka and Switzerland
This study is a case-control study, where the assumed different subtypes of type 2 diabetes in people of Tamil ethnicity and Swiss origin living in Bern, Switzerland will be examined by measuring the metabolite profiles and the…
- Trial name
- NCT05787457
- Testing
- Clinical examination, Blood testing, MRI
- Where
- Switzerland
- Volunteers
- 34 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern