Clinical trials: Fat Reduction
Central Abdominal Bulging
Evaluating the Safety and Efficacy of LIPO-202 for the Reduction of Central Abdominal Bulging Due to Subcutaneous Fat (AbCONTOUR2)
This is a multi-center, randomized, double-blinded, placebo-controlled study evaluating the safety and efficacy of LIPO-202 for the reduction of central abdominal bulging due to subcutaneous fat in non-obese subjects.
- Trial name
- NCT02398188
- Testing
- LIPO-202
- Where
- 35 sites in United States
- Volunteers
- 793 people, healthy volunteers welcome
- Sponsor
- Evofem Inc.
Abdominal Fat
VelaShape III Device in Comparison to Cryolipolysis for Circumferential Reduction
The purpose of this study is to compare the clinical performance of the VelaShape III device with CoolSculpt for reduction of the waist, love handles and flanks.
- Trial name
- NCT02143960
- Testing
- VelaShape III, CoolSculpt
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Fat Burn
Histological Evaluation of BTL-785F Device's Effect on Submental Subcutaneous Adipose Tissue
This study aims to evaluate the safety and effectiveness of the BTL-785F system equipped with the BTL-785-7 applicator for non-invasive reduction of subcutaneous submental fat.
- Trial name
- NCT06282172
- Testing
- Treatment with BTL-785-7
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Body Weight Changes
Cryolipolysis Induced Gluteal Fat Change
There was no difference in efficacy in removal of local fat on thigh by cryolipolysis through Zeltiq machine. Cryolipolysis was found to be safe for 12 week clinical trial.
- Trial name
- NCT04568187
- Testing
- zeltiq
- Where
- South Korea
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Wonik Trade Company, Korea
Adipose Tissue Reduction
Non-invasive Lipolysis on Human Thighs and Saddlebags
The study is a prospective two-arm, open-label, interventional study with four treatment procedures and two follow-up visits.
- Trial name
- NCT04221646
- Testing
- BTL-899
- Where
- Bulgaria
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Metabolic Syndrome
Efficacy of STABLOR® on Visceral Fat Mass Reduction in Patients With Metabolic Syndrome
The primary objective of the study is to assess the efficacy of STABLOR® consumption on visceral fat mass compared to placebo, in persons with metabolic syndrome during 12 weeks of consumption.
- Trial name
- OBEMINALE2 (NCT03692806)
- Testing
- Stablor
- Where
- 6 sites in France, Ireland
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- LNC THERAPEUTICS
Overweight
Efficacy and Safety of Zenoctil in Reducing Body Weight
The intention of the study is to evaluate the safety and potential body weight and body fat loss effects of a 12-week treatment with Zenoctil in a randomized, double-blind, placebo-controlled, parallel study conducted in…
- Trial name
- NCT01423617
- Testing
- Zenoctil
- Where
- Germany
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- InQpharm Group
Atherosclerotic Disease
CAPTURE Study (Polyglucosamine for Cardio & Atherosclerosis Prevention and Treatment Via Fat Uptake REduction)
This clinical investigation is intended to confirm the application of a new intended purpose and a new indication for an already certified medical device.
- Trial name
- CAPTURE (NCT06910111)
- Testing
- Polyglucosamine
- Where
- 3 sites in Italy
- Volunteers
- 240 people
- Sponsor
- Certmedica International GmbH
Subcutaneous Fat
A Study to Evaluate the Efficacy, Safety, and Tolerability of CBL-514 Injection for Reducing Subcutaneous Fat (Stage 2)
The Stage 2 of this phase 2 study will be a randomized, single-blind, placebo-controlled, parallel, and multiple-dose study to assess the efficacy, safety, and subject satisfaction of CBL-514.
- Trial name
- NCT04897412
- Testing
- CBL-514 Injection
- Where
- 5 sites in United States, Australia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Caliway Biopharmaceuticals Co., Ltd.
Fat Burn
Non-invasive Lipolysis and Improvement of Muscle Tone in Lateral Abdomen
This study will evaluate the clinical efficacy and performance of the BTL-899 device for changes in subcutaneous fat and muscle tissue in the lateral abdomen region (also referred to as flanks or "love handles").
- Trial name
- NCT05540080
- Testing
- BTL-899
- Where
- 6 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Overweight
OMNIA Efficacy on Body Fat Mass Reduction
The purpose of this clinical trial is to evaluate the safety and efficacy of a food supplement OMNIA compared to a placebo in reducing the body fat mass in 70 overweight subjects during 12 weeks treatment.
- Trial name
- PEPOLUS (NCT02516397)
- Testing
- Omnia
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Vivatech
Overweight, Obesity
Safety and Efficacy of Litramine in Overweight and Obese Subjects
Preparations that bind to nutritional fat and inhibit its absorption could be decisively meaningful for the regulation of bodyweight or obesity.
- Conditions
- Overweight, Obesity, Weight Loss
- Trial name
- NCT01233349
- Testing
- Litramine
- Where
- Germany
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- InQpharm Group
Reduction of Unwanted Fat
Non-Invasive Cooling of Fat Cells
The purpose of this study is to evaluate a non-invasive cooling device to determine if cold exposure will consistently result in a reduction of subcutaneous fat.
- Trial name
- NCT00762437
- Testing
- Zeltiq Dermal Cooling Device
- Where
- 11 sites in United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Fat Necrosis, Muscle Stimulation
Safety and Efficacy of Electronic Stimulation for Circumferential Reduction and Muscle Toning
Open-label, baseline-controlled, multi-center study evaluating an electrical muscle stimulation system for circumferential reduction and muscle toning.
- Trial name
- NCT06152900
- Testing
- Accufit
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- CynosureLutronic
Lipodystrophy
Clinical Evaluation of Venus Versa Octipolar Applicator for Reduction of Abdomen Circumference
The octipolar applicator is intended for circumference reduction treatment by reduction of adipose size and enhancement of collagen synthesis as the result thermal and non-thermal collagen stimulation.
- Trial name
- NCT02492997
- Testing
- Venus Versa, Glycerine gel
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Subcutaneous Fat
A Study to Evaluate the Efficacy and Safety of CBL-514 Injection for Reducing Subcutaneous Fat ( SUPREME-02 )
A phase 3, randomized, double-blinded, placebo-controlled study to evaluate the efficacy, safety, and tolerability of CBL-514 injection for reducing abdominal subcutaneous fat.
- Trial name
- NCT07526974
- Testing
- CBL-514 Injection, 0.9% Sodium Chloride
- Where
- 14 sites in United States, Australia and 1 more
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Caliway Biopharmaceuticals Co., Ltd.
Body Fat Disorder
Extended Follow-Up Study for Subjects Who Participated in 2010 Study
This study is being performed to follow up on subjects who participated in the initial study (ZA10-001) in 2010.
- Trial name
- JUNO (NCT01579487)
- Testing
- The Zeltiq System
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Cellulite
Radio Frequency (RF) Device for Reduction in Size of Localized Areas of the Body
The purpose of this study is to evaluate the Cutera radio frequency (RF) device for the new indication of reduction in size of localized areas of the body.
- Trial name
- NCT00953160
- Testing
- Cutera Radio Frequency Device
- Where
- 5 sites in United States
- Volunteers
- 76 people
- Sponsor
- Cutera Inc.
Body Fat Disorder
Cryolipolysis for Jawline Contouring
The purpose of this study is to evaluate the safety and efficacy of non-invasive reduction of subcutaneous fat along the jawline with Cryolipolysis.
- Trial name
- JAW (NCT03352141)
- Testing
- The ZELTIQ System
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Change in Total Body Fat Mass Percentage Loss Versus Body Weight
Evaluation of Sinetrol® Xpur in Fat Mass Reduction on Overweight and Obese Subjects
This study aims to evaluate effects of a 16-week supplementation with a polyphenol rich extract, Sinetrol® Xpur, on fat mass accumulation and body weight management improvement.Subjects were overweight or obese and received…
- Trial name
- NCT04149158
- Testing
- Sinetrol® Xpur
- Where
- Spain
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Fytexia