Clinical trials: Fat Reduction
Central Abdominal Bulging
Evaluating the Safety and Efficacy of LIPO-202 for the Reduction of Central Abdominal Bulging Due to Subcutaneous Fat (AbCONTOUR2)
This is a multi-center, randomized, double-blinded, placebo-controlled study evaluating the safety and efficacy of LIPO-202 for the reduction of central abdominal bulging due to subcutaneous fat in non-obese subjects.
- Trial name
- NCT02398188
- Testing
- LIPO-202
- Where
- 35 sites in United States
- Volunteers
- 793 people, healthy volunteers welcome
- Sponsor
- Evofem Inc.
Overweight
Efficacy and Safety of Zenoctil in Reducing Body Weight
The intention of the study is to evaluate the safety and potential body weight and body fat loss effects of a 12-week treatment with Zenoctil in a randomized, double-blind, placebo-controlled, parallel study conducted in…
- Trial name
- NCT01423617
- Testing
- Zenoctil
- Where
- Germany
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- InQpharm Group
Reduction of Unwanted Fat
Non-Invasive Cooling of Fat Cells
The purpose of this study is to evaluate a non-invasive cooling device to determine if cold exposure will consistently result in a reduction of subcutaneous fat.
- Trial name
- NCT00762437
- Testing
- Zeltiq Dermal Cooling Device
- Where
- 11 sites in United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Lipodystrophy
Clinical Evaluation of Venus Versa Octipolar Applicator for Reduction of Abdomen Circumference
The octipolar applicator is intended for circumference reduction treatment by reduction of adipose size and enhancement of collagen synthesis as the result thermal and non-thermal collagen stimulation.
- Trial name
- NCT02492997
- Testing
- Venus Versa, Glycerine gel
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Overweight and Obesity, Weight Loss
Low-level Laser and Lifestyle Modifications
The purpose of this research study is to evaluate the effectiveness of Low Level Laser Therapy in combination with Lifestyle Modifications in helping people reduce the extra weight and size in the central body region
- Trial name
- LLLT (NCT05083442)
- Testing
- Low Level Laser Therapy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cellulite
Radio Frequency (RF) Device for Reduction in Size of Localized Areas of the Body
The purpose of this study is to evaluate the Cutera radio frequency (RF) device for the new indication of reduction in size of localized areas of the body.
- Trial name
- NCT00953160
- Testing
- Cutera Radio Frequency Device
- Where
- 5 sites in United States
- Volunteers
- 76 people
- Sponsor
- Cutera Inc.
Body Fat Disorder
Cryolipolysis for Jawline Contouring
The purpose of this study is to evaluate the safety and efficacy of non-invasive reduction of subcutaneous fat along the jawline with Cryolipolysis.
- Trial name
- JAW (NCT03352141)
- Testing
- The ZELTIQ System
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Body Fat Disorder
Pilot Study on The Flanks of Asian Patients
This study will evaluate CoolSculpting and the CoolCurve applicator for non-invasive fat reduction in the flanks with sharp body curvature.
- Trial name
- NCT01623037
- Testing
- The Zeltiq System
- Where
- China
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Moderate or Severe Submental Fullness
Phase 1-2 Study of Deoxycholic Acid Injection (ATX-101) for the Reduction of Submental Fat
To evaluate the safety and potential efficacy of deoxycholic acid injection compared to placebo for the reduction of submental fat (fat below the chin).
- Trial name
- ATX-101 (NCT00618722)
- Testing
- Deoxycholic Acid Injection
- Where
- 6 sites in Australia, Canada and 1 more
- Volunteers
- 85 people
- Sponsor
- Kythera Biopharmaceuticals
Obesity
Fish Oils and Adipose Inflammation Reduction
This study is a clinical trial designed to assess whether fish oil treatments are effective in the prevention of obesity-related fat tissue (adipose) inflammation.
- Trial name
- FAIR (NCT02010359)
- Testing
- Lovaza
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Subcutaneous Fat
A Study to Evaluate the Efficacy, Safety and Tolerability of CBL-514 Injection for Reducing Subcutaneous Fat (Stage 1)
The Stage 1 of this phase 2 study is an open-label single ascending dose (SAD) study. The primary objectives are to evaluate the safety and tolerability of injection lipolysis with CBL-514.
- Trial name
- NCT04575467
- Testing
- CBL-514
- Where
- Australia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Caliway Biopharmaceuticals Co., Ltd.
Moderate or Severe Submental Fullness
Patient Experience Study of Deoxycholic Acid Injection
The objectives of this study are to determine the safety of deoxycholic acid subcutaneous (SC) injections in the submental area and to evaluate the effects of four interventions, relative to placebo in the submental area…
- Trial name
- NCT02007434
- Testing
- Deoxycholic Acid Injection, Cold Compress, Lidocaine / Epinephrine
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Kythera Biopharmaceuticals
Weight Loss
An Evaluation of the Effect of the Erchonia Laser for Non-invasive Reduction of Submental Fat
The purpose of this clinical study is to determine the effectiveness of the Erchonia® CFL (manufactured by Erchonia Corporation (the Company), in providing noninvasive fat reduction in the submental area.
- Trial name
- NCT05954065
- Testing
- Erchonia CFL Laser
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Erchonia Corporation
Body Fat Disorder
Multiple CoolSculpting Treatment Study
To evaluate the safety of same-day CoolSculpting treatments and to assess the impact on serum lipids and liver-related tests.
- Trial name
- NCT01814007
- Testing
- The Zeltiq CoolSculpting System
- Where
- 3 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Body Fat Disorder
CoolSculpting System
Evaluate the safety and efficacy of multiple, simultaneous CoolSculpting cycles for the purpose of non-invasive fat reduction.
- Trial name
- ELI (NCT04506307)
- Testing
- The ZELTIQ System
- Where
- 4 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Excess Abdominal Fat
UltraShape Power for Abdominal Fat and Circumference Reduction
Prospective, one arm, baseline-controlled, clinical study for the evaluation of the UltraShape Power treatment using the U-Sculpt Power Transducer for non-invasive abdominal fat and circumference reduction.
- Trial name
- NCT02748928
- Testing
- UltraShape Power
- Where
- 8 sites in United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Adipose Tissue Atrophy
Clinical Evaluation of a 1060 nm Diode Laser, PEMF and Vacuum Assisted MP RF for Non-invasive Fat Reduction
Open-label, baseline-controlled, multi-center study evaluating a 1060 nm diode laser, pulsed electromagnetic fields and vacuum assisted radio frequency for non-invasive fat reduction of the abdomen and flanks.
- Trial name
- NCT04012814
- Testing
- Venus Bliss
- Where
- 5 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Body Fat Disorder
Feasibility Study of a Belt Applicator
Evaluate the safety and feasibility of non-invasive fat reduction in the outer thigh with a belt applicator. Applicator design and treatment parameters will be evaluated.
- Trial name
- NCT01767142
- Testing
- The Zeltiq System with Modified Belt Applicator
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Obesity, Weight Loss
Evaluation of Safety, Efficacy and Thermogenesis-induction of RZL-012 in Overweight and Obese Volunteers
Obesity is a direct result of food-intake in excess of body energy expenditure. Thus, induction of increased energy expenditure via the activation of thermogenesis at targeted anatomical sites can counterbalance obesity.
- Conditions
- Obesity, Weight Loss, Overweight and Obesity
- Trial name
- NCT03171415
- Testing
- RZL-012
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Raziel Therapeutics Ltd.
Chronic Pancreatitis
Fat Malabsorption in Chronic Pancreatitis
The objective of this study is to evaluate the malabsorption blood test (MBT), stool coefficient of fat absorption (CFA) and stool bomb calorimetry (BC) methods as potential screening or diagnostic tests for reduced exocrine…
- Trial name
- NCT02849704
- Testing
- Creon36™
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia