Clinical trials: Fatigue, Mental
Cardiac Failure, Heart Failure
Insomnia Self-Management in Heart Failure
Chronic insomnia may contribute to the development and exacerbation of heart failure (HF), incident mortality and contributes to common and disabling symptoms (fatigue, dyspnea, anxiety, depression, excessive daytime sleepiness…
- Conditions
- Cardiac Failure, Heart Failure, Congestive Heart Failure, Heart Failure, Congestive
- Trial name
- HSS (NCT02660385)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Self-Management Education for Heart Failure
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Yale University
Transcutaneous Vagus Nerve Stimulation on Fibromyalgia
Transcutaneous Vagus Nerve Stimulation on Fibromyalgia- Double-blind, Sham-controlled Randomized Clinical Trial
Stimulation of the vagus nerve, a parasympathetic nerve that controls the digestive, the vascular and immune systems, produces pain relief in various clinical conditions.
- Trial name
- TVNS- Fibro (NCT06912334)
- Testing
- tVNS
- Where
- Greece
- Volunteers
- 120 people
- Sponsor
- National and Kapodistrian University of Athens
Exogenous Ketosis, Endurance Cycling Performance
The Effects of Exogenous Ketosis on Ultra-endurance Recovery and Performance
The study aims to investigate the effects of post-exercise and pre-sleep ketosis via oral ketone ester supplementation on physical and mental recovery during a multi-day cycling stage race.
- Conditions
- Exogenous Ketosis, Endurance Cycling Performance, Fatigue; Muscle, Heart, Fatigue, Mental
- Trial name
- NCT06965491
- Testing
- Ketone ester supplement
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Burnout, Compassion Fatigue
The Effect of Mindfulness Meditation
Cancer is a disease that causes the most deaths worldwide and is challenging for patients and caregivers both physically and psychosocially.
- Conditions
- Burnout, Compassion Fatigue, Psychological Well-Being
- Trial name
- NCT06282913
- Testing
- Mindfulness Meditation
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Gulhane Training and Research Hospital
Fatigue, Cognitive Dysfunction
Fatigue and Cognitive Dysfunction After Allogeneic Stemcell Transplantation, Prospective PET Study
This study is the academic study and continuation and further development of a prior project under the leadership of Professor LeBlanc.
- Trial name
- NCT06363396
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Gynecologic Cancer Survivors, Sleep Quality
Effects of Bright Light on Sleep Quality, Fatigue , and Mood Symptoms in Survivors With Gynecologic Cancer
Objective: This study aimed to examine the efficacy of light therapy in improving sleep quality, reducing fatigue, and alleviating emotional symptoms among patients diagnosed with gynecologic cancer.
- Conditions
- Gynecologic Cancer Survivors, Sleep Quality, Fatigue, Mood Symptoms
- Trial name
- NCT07132580
- Testing
- Re-Timer® light therapy glasses, Usual Care
- Where
- Taiwan
- Volunteers
- 94 people
- Sponsor
- Chang Gung Memorial Hospital
Depressive Disorder
A 12-weeks Study to Evaluate Sulforaphane in the Treatment of Depression
Major depressive disorder is a serious, recurrent and disabling mental disorder, which is the second leading cause of years lost to disability worldwide.
- Trial name
- NCT04246905
- Testing
- sulforaphane, placedo, selective 5 - HT reuptake inhibitors (SSRI)
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Central South University
Distress, Emotional, Depression, Anxiety
Training in Evidence-based Treatments in Psycho-Oncology
The goal of this research study is to train psychotherapists to administer individualized evidence-based psychotherapies in a cancer care setting to patients and caregivers with elevated levels of distress.
- Conditions
- Distress, Emotional, Depression, Anxiety, Fatigue, Pain
- Trial name
- NCT05674357
- Testing
- Individualized Evidence-Based Therapy in Cancer (Patients and Caregivers), Training in Individualized Evidence-Based Therapy in Cancer (Therapists)
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Massachusetts General Hospital
Maximum Force, Strength Endurance
The Effects of Caffeine and Vitamin C on Maximum Strength and Strength Endurance in Adolescents With Mild Mental Fatigue
Objective To investigate the independent and combined effects of caffeine and vitamin C on maximal strength and strength endurance in female adolescents with mild mental fatigue.
- Conditions
- Maximum Force, Strength Endurance, Mental Fatigue
- Trial name
- NCT07726745
- Testing
- 1RM squats and bench presses; repetitions at 65% of 1RM for squats and bench presses
- Volunteers
- 40 people
- Sponsor
- Yunliang Zhang
COVID-19
Effectiveness and Safety of Two Vitamin D3 Supplementation Regimens in Adults with Early-stage COVID-19
This study aimed to determine the effectiveness and safety of individualized vitamin D3 supplementation in adult patients with early-stage severe COVID-19.
- Trial name
- VDCOVID19ACUTE (NCT06585995)
- Testing
- vitamin D (cholecalciferol) supplementation
- Where
- Mexico
- Volunteers
- 216 people
- Sponsor
- Escuela Militar de Graduados de Sanidad, SEDENA
Anxiety Disorder, Breast Cancer
Acupuncture or Self-Acupuncture in Managing Cancer-Related Fatigue in Women Who Have Received Chemotherapy for Stage I, Stage II, or Stage IIIA Breast Cancer
RATIONALE: Acupuncture may help relieve fatigue caused by breast cancer. It is not yet known whether acupuncture is more effective than self-acupuncture in managing fatigue in women with breast cancer.
- Conditions
- Anxiety Disorder, Breast Cancer, Depression, Fatigue
- Trial name
- NCT00957112
- Testing
- acupuncture therapy, standard follow-up care
- Where
- United Kingdom
- Volunteers
- 320 people
- Sponsor
- University of Manchester
Lung Cancer, Nonsmall Cell, Lung Cancer Non-Small Cell Stage 0
Effect of Qigong on the Symptom Clusters of Dyspnea, Fatigue, and Anxiety.
Effects of Qigong on symptom clusters of dyspnea, fatigue, and anxiety in Vietnamese lung cancer patients: A randomized control trial
- Conditions
- Lung Cancer, Nonsmall Cell, Lung Cancer Non-Small Cell Stage 0, Lung Cancer, Nonsmall Cell, Stage I, Lung Cancer Non-Small Cell Stage II
- Trial name
- NCT02977845
- Testing
- Qigong
- Where
- Hong Kong
- Volunteers
- 162 people
- Sponsor
- Nam Dinh University of Nursing
Mindfulness Training, Neurocognitive Function
Mindfulness Training, Mental Fatigue, Endurance Performance and Neurocognitive Functions
Mental fatigue has been suggested that would impair neurocognitive functions and sports performance. On the other hand, mindfulness training (MT) seems to as a promising approach to attenuate mental fatigue and counteract its…
- Conditions
- Mindfulness Training, Neurocognitive Function, Sports Performance, Mental Fatigue
- Trial name
- NCT05452460
- Testing
- Mindfulness intervention
- Where
- Taiwan
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Auditory Fatigue
Evaluation of Auditory Fatigue in Medical Regulation Assistants
Auditory monitoring of employees is currently based on pure-tone audiometry. However, this clinical examination does not prevent from deafness but established it a posteriori.
- Trial name
- EchoSam (NCT02384681)
- Testing
- Exposure to auditory fatigue
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Aneurysmal Subarachnoid Hemorrhage
Pharmaceutical Treatment of Fatigue After Aneurysmal Subarachnoid Hemorrhage
Many people who have undergone subarachnoid hemorrhage from an aneurysm (an artery of a vein in the brain) struggle with a pronounced fatigue as well as a number of other sequelae such as impaired concentration, memory deficits…
- Trial name
- NCT03209830
- Testing
- OSU 6162
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Stage, Breast Cancer
Prophylactic Treatment of Sleep/Fatigue Before and During Chemotherapy
Women with breast cancer complain of poor sleep and fatigue during chemotherapy which affect their mood, their memory and their quality of life.
- Trial name
- NCT01542983
- Testing
- Brief behavioral treatment for insomnia and bright light, treatment as usual
- Where
- United States
- Sponsor
- University of California, San Diego
Iron Deficiency
Intravenous High Dose Iron in Blood Donors
2-3% of the population participates in blood donation programmes. Traditionally, safety issues in transfusion medicine have been concentrating on product and recipient safety.
- Trial name
- IronWoMan (NCT01787526)
- Testing
- ferric carboxymaltose, oral iron
- Where
- Austria
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Major Depressive Disorder
Omega-3 Fatty Acids as Adjunct Treatment for Major Depressive Disorder
The primary objective of the study was to determine the effects of 10-week adjunctive supplementation with 2 doses of LCn-3 fatty acids (fish oil) on cortical functional activity and biochemistry in adolescents with MDD.
- Trial name
- NCT00511810
- Testing
- Low Dose Fish Oil, High Dose Fish Oil
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Cincinnati
Stroke, Post-Stroke Fatigue
Understanding Mental Fatigue After Stroke
Mental fatigue is a major problem for stroke survivors and sometimes remains present years after the event. It is often rated as the most persisting and frustrating symptom.
- Conditions
- Stroke, Post-Stroke Fatigue, Fatigue
- Trial name
- MenFAS (NCT04866420)
- Testing
- The MenFAS Study
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- Oxford Brookes University
Multiple Sclerosis
Effectiveness of Cryotherapy on the Fatigue of Patients With Multiple Sclerosis
the aim of the study is to evaluate the effectiveness of partial-body cryotherapy (PBC) on the symptoms of patients with multiple sclerosis during a rehabilitation stay.
- Trial name
- CRYOSEP (NCT05219201)
- Testing
- partial-body cryotherapy chamber session
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Fondation Ildys