Clinical trials: Fatigue, Mental
Burnout Syndrome, Depression Disorder
The COMET Study: a Prospective COhort of MEdical residenTs to Assess Professional, Personal and Psychological Trajectories of Residents in General Internal Medicine
Introduction. Switzerland, like most Western countries, faces a paradox: an ageing, multimorbid population needs general internal medicine (GIM) physicians more than ever, yet fewer young doctors choose - and stay in - the…
- Conditions
- Burnout Syndrome, Depression Disorder, Insomnia, Perceived Stress
- Trial name
- COMET (NCT07707453)
- Where
- 3 sites in Switzerland
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Fribourg
Breast Cancer, Fatigue
Three Different Programs of Paced Breathing in Treating Hot Flashes in Women
RATIONALE: Paced breathing may be an effective way to reduce the number and severity of hot flashes in women who have survived breast cancer.
- Conditions
- Breast Cancer, Fatigue, Hot Flashes, Sleep Disorders
- Trial name
- NCT00569166
- Testing
- Paced breathing (15 min once daily, 6 breaths/min), Paced breathing (15 min twice daily, 6 breaths/min), Paced breathing (10 min once daily, 14 breaths/min)
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Mayo Clinic
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma
To Decrease Fatigue With Light Therapy
Cancer related fatigue (CRF) is one of the most prevalent and distressing long-term complaints reported by (non-) Hodgkin survivors.
- Trial name
- SPARKLE (NCT03242902)
- Testing
- Light therapy intensity 1, Light therapy intensity 2
- Where
- 9 sites in Netherlands
- Volunteers
- 166 people
- Sponsor
- The Netherlands Cancer Institute
Post-Poliomyelitis Syndrome
Study of Mental Fatigue in Polio Survivors
Post-Poliomyelitis Syndrome (PPS) is the term describing the new problems affecting polio survivors many years after recovery from paralytic polio. Among the symptoms, fatigue is one of the most frequent and debilitating.
- Trial name
- NCT00487487
- Where
- United States
- Sponsor
- Uniformed Services University of the Health Sciences
Lactate Blood Increase, Trauma Blunt
Lactate Monitoring in Traumatic Long Bone Fractures Requiring Emergent Surgical Intervention
Serum lactate has been utilized as a standard in guiding management of orthopedic injuries. Elevated preoperative lactate has been associated with a higher likelihood of postoperative complications.
- Conditions
- Lactate Blood Increase, Trauma Blunt, Trauma, Secondary, Injury Traumatic
- Trial name
- NCT05611398
- Testing
- Orthopedic Surgery
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Arrowhead Regional Medical Center
Somatoform Disorders, Fibromyalgia
Immune Patterns in Pain Patients DSM-IV
The purpose of this study is to define subgroups of patients with somatoform disorders due to DSM-IV by immunological, psychological and genetic characterization.
- Conditions
- Somatoform Disorders, Fibromyalgia, Myofascial Pain Syndrome, Diffuse, Depression
- Trial name
- IPPPDIV (NCT01106339)
- Where
- Germany
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Sjogren's Syndrome, Fatigue
Fatigue in Primary Sjögren's Syndrome
Fatigue is a common clinical finding in Primary Sjögren's syndrome (PSS). In PSS, there is not enough data about the conditions in which fatigue develops and which clinical conditions the disease is associated with.
- Conditions
- Sjogren's Syndrome, Fatigue, Pain Syndrome, Depression
- Trial name
- NCT04802577
- Testing
- FACT-F questionnaire, Beck Depression Inventory, Beck Anxiety Inventory
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Long COVID, Brain Fog
Effect of Probiotic Strain Lactobacillus Paracasei PS23 on Brain Fog in People With Long COVID
The goal of this clinical trial is to test whether the intervention of probiotics supplement can improve symptoms of long covid syndrome. Participants will be given probiotics or placebo capsules for two month.
- Conditions
- Long COVID, Brain Fog, Cognitive Change
- Trial name
- COVID-19 (NCT06348212)
- Testing
- Lactobacillus paracasei PS23, microcrystalline cellulose
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Major Depressive Disorder
Open-Label Treatment With Duloxetine Hydrochloride Once-Daily Dosing for Evaluation of Stabilization Dose in Patients With Major Depression
The purposes of this study are to determine: The safety of duloxetine and any side effects that might be associated with it. Whether duloxetine can help patients with major depression.
- Trial name
- NCT00042562
- Testing
- duloxetine
- Where
- 23 sites in United States
- Sponsor
- Eli Lilly and Company
Posttraumatic Stress Disorder, Major Depressive Disorder
An Augmented Training Program for Preventing Post-Traumatic Stress Injuries Among Diverse Public Safety Personnel
Public safety personnel (PSP; e.g., border services personnel, correctional workers, firefighters, paramedics, police, public safety communicators) are frequently exposed to potentially psychologically traumatic events.
- Conditions
- Posttraumatic Stress Disorder, Major Depressive Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT05530642
- Testing
- Emotional Resilience Skills Training (ERST)
- Where
- Canada
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Regina
Stage, Breast Cancer
Prophylactic Treatment of Sleep/Fatigue Before and During Chemotherapy
Women with breast cancer complain of poor sleep and fatigue during chemotherapy which affect their mood, their memory and their quality of life.
- Trial name
- NCT01542983
- Testing
- Brief behavioral treatment for insomnia and bright light, treatment as usual
- Where
- United States
- Sponsor
- University of California, San Diego
Red Tide, Neurologic Disorder
Investigating Health Impacts of Exposure to Harmful Algal Blooms
The goals of this project are to study the biological effects of environmental toxins (ET), in particular aquatic toxins such as brevetoxins (PbTx) and microcystin or their metabolites.
- Conditions
- Red Tide, Neurologic Disorder, Florida
- Trial name
- NCT06883227
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Roskamp Institute Inc.
Fibromyalgia
Clinical Outcomes After Dry Needling on Cervical Muscles, and Quality of Life, in Patients With Fibromyalgia Syndrome.
Objectives: The purpose of the current randomized clinical trial is to compare the effectiveness of dry needling versus myofascial release therapy on myofascial trigger points (MTrPs) in cervical muscles, quality of life…
- Trial name
- NCT03015662
- Testing
- Dry Needling Therapy, Myofascial Release Therapy
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Universidad de Almeria
Sleep Disturbance, Fatigue
Treating Disrupted Sleep in Individuals With Inflammatory Bowel Disease
The purpose of this study is to determine if either a targeted type of talk therapy (Phase I) or medication, Wellbutrin, (Phase II) improve sleep disturbance and/or fatigue in individuals with Inflammatory Bowel Disease (IBD).
- Conditions
- Sleep Disturbance, Fatigue, Inflammatory Bowel Disease
- Trial name
- NCT02162862
- Testing
- Behavioral Counseling, bupropion-SR
- Where
- 2 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Eva Szigethy
Compassion Fatigue
Effect of a Compassion Fatigue Resiliency Program
This study aimed to conduct a short- and long-term Compassion Fatigue Resiliency Program and compare its impact on nurses' professional quality of life, perceived stress and resilience.
- Trial name
- NCT04372303
- Testing
- Compassion Fatigue Resiliency Program (CFRP)
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Koc University Hospital
Post Partum Depression
Effectiveness of Mat Pilates and Aerobic Training on Fatigue and Depression
The aim is to see fatigue and depression levels in postpartum females and to evaluate ho two well-known exercises, Mat Pilates and Aerobic training can help to reduce the fatigue levels in postpartum females
- Trial name
- NCT04813341
- Testing
- Pilates training, Aerobic Training
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Breast Cancer, Fatigue
Using Pranayama and Deep Breathing Exercises to Reduce Cancer-Related Fatigue and Insomnia During Radiotherapy
The study aims to evaluate the effectiveness of pranayama and deep breathing exercise in reducing fatigue and insomnia in patients receiving radiotherapy due to breast cancer.
- Conditions
- Breast Cancer, Fatigue, Insomnia
- Trial name
- NCT04441827
- Testing
- breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Thoracic Surgery, Pain, Postoperative
Using Hypnosis and Virtual Reality During Pre and Postoperative Cardiovascular Surgery.
Nowadays, the use of cognitive behavioral therapies has become quite common in the clinical care. Different non-pharmacological techniques, including hypnosis and virtual reality are currently used as complementary tools in the…
- Conditions
- Thoracic Surgery, Pain, Postoperative, Anxiety, Fatigue
- Trial name
- VRHypnICU (NCT03820700)
- Testing
- Hypnosis (Hypn), Virtual reality (VR), Virtual reality hypnosis (VRH)
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University of Liege
Chronic Inflammation, Chronic Pain
Gulf War Illness Inflammation Reduction Trial
The primary objective of this clinical trial is to determine if treatment with an anti-inflammatory drug (delayed-release prednisone) improves the health-related quality of life (HRQOL) of veterans with Gulf War Illness (GWI).
- Conditions
- Chronic Inflammation, Chronic Pain, Fatigue, Cognitive Impairment
- Trial name
- GWIIRT (NCT02506192)
- Testing
- Modified-Release Prednisone
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center