Clinical trials: Fatigue, Mental
Long COVID
Neurobiological Underpinnings of Neuropsychological Consequences in Long COVID
Objectives: To describe the standardized evaluation of the psychological and cognitive function of long COVID patients and their evolution, to compare immunological and HPA-axis related biomarkers between long COVID patients and…
- Trial name
- Cov-N-Psy (NCT06279936)
- Testing
- Neuropsychological battery, Surveys and symptom severity questionnaires, Blood withdrawal
- Where
- Belgium
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Healthy
Hormonal Balance in Stress, Fatigue, and Recovery: Dynamics of Pre-Competition Responses
This observational study investigates how elite athletes respond physiologically and psychologically to pre-competitive stress in the context of a high-stakes performance test.
- Trial name
- NCT06917677
- Testing
- 2000-meter maximal effort test on rowing ergometer
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Compassion Fatigue
Effect of Nurse-Led Intervention Programme Professional Quality of Life and Psychological Distress in Nurses
Nurses are at risk in terms of burnout and empathic fatigue. Therefore, efforts to protect the mental health of nurses are very important. It is stated that the studies conducted are mostly descriptive and not interventional.
- Trial name
- NCT03914898
- Testing
- Nurse led intervention group
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Clinical Alarms
Reducing the Risk of Alarm Fatigue Through the Use of Focused Management in Safety Huddles
Context: Alarm fatigue is a threat to hospital patient safety. National surveys reveal that high alarm rates interrupt patient care, reduce trust in alarms, and lead clinicians to disable alarms entirely.
- Trial name
- NCT02319421
- Testing
- Alarm Reduction Script
- Where
- United States
- Volunteers
- 812 people
- Sponsor
- Children's Hospital of Philadelphia
Ketonemia, Mental Fatigue
Exogenous Ketone Supplementation and Cognitive Function During Exercise
15 healthy trained males will volunteer to participate in this study. there will be 2 treatments: Ketone esters supplementation and iso-caloric carbohydrate.
- Conditions
- Ketonemia, Mental Fatigue, Ketosis
- Trial name
- NCT04576026
- Testing
- mental fatiguing task, 45 - minute simulated soccer game, cognitive function
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Depressive Disorder, Fatigue Syndrome, Chronic
Glucocorticoid Effects on Cellular Cytokine Release
A variety of hormones and immune system processes are responsible for how the body responds to illness. This study concentrates on how the hormone cortisol effects the release of immune system factors called cytokines.
- Conditions
- Depressive Disorder, Fatigue Syndrome, Chronic, Fibromyalgia, Healthy
- Trial name
- NCT00001415
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Laughter Yoga
The Effect of Laughter Yoga on the Secondary Traumatic Stress Level and Psychological Well-Being of Midwives
Aim: The aim of this study is to determine the effect of laughter yoga, which includes various relaxing practices, on secondary trauma levels and psychological well-being of midwives.
- Trial name
- NCT05933915
- Testing
- group-based laughter yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Covid19, Neurocognitive Dysfunction
Long-term Neurocognitive and Psychiatric Consequences in Severe COVID-19 Survivors.
Long-term neurocognitive and psychiatric consequences of COVID-19 remain mostly unknown to date. It has been reported that coronaviruses cause direct central nervous system infection (Needham et al. 2020).
- Trial name
- NPQCOVID (NCT05019300)
- Testing
- Exposure: COVID-19 severity
- Where
- Chile
- Volunteers
- 80 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Sleep, Occupational Stress
A Proactive Intervention Promoting Strategies for Sleep and Recovery in Nurses
Considering the known challenges facing newly graduated nurses, there are possibilities to implement preventive actions. The aim of the current study was to evaluate the effects of a preventive intervention among newly graduated…
- Conditions
- Sleep, Occupational Stress, Fatigue, Behavior, Health
- Trial name
- NCT04246736
- Testing
- Bädda för Kvalitet
- Where
- 7 sites in Sweden
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Heart Diseases, Cardiovascular Diseases
Strong People Strength Training Study
The Strong People Strength Training study aims to assess whether a community-based progressive strength training program can improve risk factors for diabetes and heart disease in older rural adults.
- Conditions
- Heart Diseases, Cardiovascular Diseases, Diabetes, Sedentary Lifestyle
- Trial name
- NCT04203563
- Testing
- Strong People Strength Training
- Where
- 6 sites in United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Cornell University
Cognitive Reserve, Aging
Cognitive Reserve and Post-Fatigue Recovery in Older Adults
As people grow older, it is common to experience a drop in physical stamina and memory functions. This can make recovering from daily physical and mental fatigue more difficult, which directly impacts an individual's independent…
- Conditions
- Cognitive Reserve, Aging, Mental Fatigue, Fatigue
- Trial name
- NCT07667985
- Where
- Turkey (Türkiye)
- Volunteers
- 696 people, healthy volunteers welcome
- Sponsor
- Uşak University
Healthy Adults
The Effect of Different Physical Activity Strategy on Cognitive Efficiency and Mental Fatigue Resistance
The main aim of this biomedical study is to determine the effect of moderate-intensity aerobic exercise, before and after an 8-hour workday and a combined work model, on the performance and efficiency of cognitive functions…
- Trial name
- NCT07130825
- Testing
- 8 hours simulated mental workday, Moderate intensity aerobic activity, Combined work model
- Where
- Lithuania
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Cancer, Fatigue
Health-related Quality of Life-intervention in Survivors of Breast and Other Cancers Experiencing Cancer-related Fatigue Using Traditional Chinese Medicine: The HERBAL Trial
This study is a phase 2, randomized, double-blinded, placebo-controlled trial to evaluate the efficacy and safety of a Traditional Chinese Medicine decoction, the modified Xiang Bei Yang Rong Tang, in alleviating cancer related…
- Conditions
- Cancer, Fatigue, Cognitive Impairment
- Trial name
- HERBAL (NCT04104113)
- Testing
- Modified Xiang Bei Yang Rong Tang
- Where
- Singapore
- Volunteers
- 80 people
- Sponsor
- National University of Singapore
Fatigue, Depression
Health Literacy Assessment and Intervention to Reduce Disparities: FLIGHT/VIDAS II
The purpose of this study will to be to evaluate the effects of a mobile intervention focused on improving the chronic disease self management skills of individuals with low health literacy.
- Conditions
- Fatigue, Depression, Pain, Sleep Wake Disorders
- Trial name
- FV2 (NCT02922439)
- Testing
- Tailored Intervention, Control Intervention
- Where
- United States
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Multiple Sclerosis, Quality of Life
Impact of Exercise on "Invisible" Symptoms and Quality of Life in Multiple Sclerosis Individuals
Patients with multiple sclerosis (MS) struggle on a daily basis with accompanying, "Invisible" symptoms like primary fatigue, pain and emotional-cognitive disorders.
- Conditions
- Multiple Sclerosis, Quality of Life, Motivation, Pain
- Trial name
- NCT03768830
- Testing
- Exercise training
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rijeka
Lymphedema
Causes of Kinesiophobia in Lymphedema
In this study, the reason for the fear of movement in patients with lymphedema will be investigated and recommendations will be given to the patients to eliminate it.
- Trial name
- NCT05105594
- Testing
- survey application
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Maximum Force, Strength Endurance
The Effects of Caffeine and Vitamin C on Maximum Strength and Strength Endurance in Adolescents With Mild Mental Fatigue
Objective To investigate the independent and combined effects of caffeine and vitamin C on maximal strength and strength endurance in female adolescents with mild mental fatigue.
- Conditions
- Maximum Force, Strength Endurance, Mental Fatigue
- Trial name
- NCT07726745
- Testing
- 1RM squats and bench presses; repetitions at 65% of 1RM for squats and bench presses
- Volunteers
- 40 people
- Sponsor
- Yunliang Zhang
Fibromyalgia
The Effect of Milnacipran in Patients With Fibromyalgia
Use of the drug Milnacipran will reduce ventricular lactate levels and processing time for completing complex tasks relative to placebo.
- Trial name
- NCT01108731
- Testing
- Milnacipran
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Beth Israel Medical Center
Breast Cancer
Fatigue in Breast Cancer Patients Undergoing Radiotherapy-eSMART-MH
The purpose of this study is to determine if an avatar-based depression self-management intervention (eSMART-MH) once a week for the duration of the participant's radiation treatment will significantly reduce depressive symptoms.
- Trial name
- NCT02759549
- Testing
- eSMART-MH, Mobile Mood Tracking (Mood 24/7), Theater Testing Workshop
- Where
- 4 sites in United States
- Sponsor
- Emory University
Anxiety Disorder, Depression
Nursing Intervention in Supporting Family Caregivers of Patients Undergoing Stem Cell Transplant
This randomized clinical trial studies nursing intervention in supporting family caregivers (FCs) of patients undergoing stem cell transplant. A nursing intervention may help prepare FCs support the recovery of the patients
- Conditions
- Anxiety Disorder, Depression, Fatigue
- Trial name
- NCT01341873
- Testing
- educational intervention, psychosocial support for caregiver, quality-of-life assessment
- Volunteers
- healthy volunteers welcome
- Sponsor
- City of Hope Medical Center