Clinical trials: Fatigue, Mental
Sleep Disorder
Self-Acupressure on Pain, Fatigue and Sleep Quality in Systemic Lupus Erythematosus
The aim of this study is to examine the effect of Self-acupressure application on pain, fatigue and sleep quality in sle patients.
- Trial name
- NCT05453422
- Testing
- Self-Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Istanbul Sabahattin Zaim University
Delayed Sleep Phase Syndrome
Are Patients Suffering From DSPS Show Compromising in Everyday Functions and Abilities Before Handling the Disorder?
The purpose of this study is to determine whether the known treatment for DSPS also improve the cognitive ability and mood of the patients.
- Trial name
- NCT02962037
- Testing
- Melatonin and light therapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lilach Kemer
Fibromyalgia
Pranayama and Diaphragmatic Breathing Exercise Applied to Female Patients With Fibromyalgia
Female patients diagnosed with fibromyalgia were divided into pranayama breathing exercise, diaphragm breathing exercise and control groups.
- Trial name
- NCT05840939
- Testing
- Pranayama, diaphragm breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Inonu University
Long Covid19
Effectiveness of Testofen Compared to Placebo on Long COVID Symptoms
This is a double blind, randomised, placebo-controlled trial to evaluate orally-dosed Testofen (a specialised extract of Trigonella foenum-graecum (Fenugreek) seed) compared to placebo on post COVID-19 symptoms in otherwise…
- Trial name
- NCT05795816
- Testing
- Testofen, Microcrystalline cellulose
- Where
- Australia
- Volunteers
- 150 people
- Sponsor
- RDC Clinical Pty Ltd
Post-Treatment Lyme Disease
Transcranial Direct Current Stimulation for Post Treatment Lyme Disease
The primary purpose of this pilot study is to investigate a novel approach to the treatment of cognitive symptoms that persist despite prior antibiotic treatment for Lyme disease (Post treatment Lyme Disease or PTLD).
- Trial name
- NCT06915324
- Testing
- Transcranial Direct Current Stimulation (tDCS), Cognitive training
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- Columbia University
Fibromyalgia, Chronic Fatigue Syndrome (CFS)
Effect of Physical Exercise and Neuromodulation on Pain, Sleep and Fatigue in Patients With Fibromyalgia
Fibromyalgia (FMS) is a chronic, multifactorial syndrome characterized by widespread pain, fatigue, and cognitive disturbances. This interventional study evaluates the impact of structured physical training using…
- Trial name
- NCT07242573
- Testing
- Physical Training Program, NESA X-Signal, Conventional Physiotherapy
- Where
- Poland
- Volunteers
- 75 people
- Sponsor
- National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland
Breast Cancer
Epigenetics and Psychoneurologic Symptoms in Women With Breast Cancer
This study examines the relationship among epigenetic alterations and the development and persistence of psychoneurologic symptoms (cognitive dysfunction, depressive symptoms, anxiety, fatigue, sleep disturbance, and pain) in…
- Trial name
- NCT01411943
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Virginia Commonwealth University
Post-acute Infectious Syndrome (PAIS), Post-COVID-19 Condition (PCC or Long COVID)
Post-acute Infectious Syndrome - Aripiprazole Symptom Evaluation (PAIS-AriSE)
Post-acute infectious syndrome (PAIS), including post-COVID-19 condition (PCC or Long COVID), can develop after an infection and may cause persistent symptoms such as fatigue, problems with memory and concentration ("brain fog")…
- Trial name
- PAISE-AriSE (NCT07714213)
- Testing
- Aripiprazole (low-dose, 1mg)
- Where
- Germany
- Volunteers
- 138 people
- Sponsor
- Christiana Franke
Cognitive Impairment, Old Age; Debility
Dietary Supplementation and Cognitive Functions in the Elderly
In recent years, globally, there has been a growth in both the size and the proportion of older adults in the world population. The World Health Organization (WHO) has estimated that by 2030, 1 in 6 people will be 60 years of age…
- Trial name
- ESPINS (NCT06352099)
- Testing
- Dietary supplement with micronised diosmin, hesperidin and herbal extracts
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Restless Leg Syndrome in Pregnancy
Comparative Effects of Aerobic and Muscle Relaxation Exercises in Pregnant Women With Restless Leg Syndrome
This study will be a randomized controlled trial and will be conducted in the Gynecology and Physiotherapy departments of Valencia Health Clinic, Lahore. Non-probability purposive sampling will be used to collect data.
- Trial name
- NCT07628387
- Testing
- aerobic exercises, progressive muscle relaxation
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Fatigue, Cognitive Deficit
Effects of PEA-LUT on Frontal Lobe Functions and GABAergic Transmission in Long-Covid Patients
The study explore the efficacy of PEA-LUT in patients suffering from neurological symptoms of Long-Covid
- Conditions
- Fatigue, Cognitive Deficit, COVID-19, Neurophysiologic Abnormality
- Trial name
- PL-PC19 (NCT05311852)
- Testing
- palmitoylethanolamide co-ultramicronized with antioxidant flavonoid luteolin (PEA-LUT)
- Where
- Italy
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Department of Neurorehabilitation, Hospital of Vipiteno-Sterzing (BZ) Italy
Central Fatigue, Altitude Training
Effect of Hot Spring Therapy on Central Fatigue Elimination During Altitude Training
This randomized controlled trial investigates the effects of hot spring balneotherapy on central fatigue elimination in adolescent rowers undergoing altitude training at approximately 1600 meters (Tengchong, Yunnan).
- Conditions
- Central Fatigue, Altitude Training, Cognitive Impairment, Hydrotherapy
- Trial name
- HSCF-AHT (NCT07615478)
- Testing
- Natural recovery, Hot water immersion, Hot spring balneotherapy
- Where
- China
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Macao Polytechnic University
Healthy
Effect of Sleep Extension in Prevention to Sleep Deprivation
The approach of a competition can be associated to a decrease in sleep duration and quality which can negatively impact athlete's performance and health (injury risk, fall, accident).
- Trial name
- SLEEPERF (NCT06928168)
- Testing
- Total sleep deprivation, partial sleep deprivation, Reproductibility
- Where
- France
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Polycystic Ovarian Syndrome (PCOS), Pittsburg Sleep Quality Index
Diaphragmatic Breathing Exercises on Sleep Disorders un Polycystic Ovarian Syndrome
Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder in females in reproductive age and not completely understood. Women with PCOS appear to have an increased frequency of sleep problems.
- Conditions
- Polycystic Ovarian Syndrome (PCOS), Pittsburg Sleep Quality Index, Fatigue Severity Scale, Insomnia Severity Index
- Trial name
- NCT07698925
- Testing
- Diaphragmatic breathing exercises, Lifestyle modification advices
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Adly A Adam
Sickle Cell Disease
Efficacy of Designed Exercise Program on Pain and Quality of Sleeping in Patient With Sickle Cell Disease Anemia.
Background: Pain and sleep disturbance are the most common problems experienced by adult patients with sickle cell disease anemia.
- Trial name
- SCDA (NCT05894161)
- Testing
- Exercise training program
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Healthy, Mental Fatigue
Mental Fatigue and Industrial Work Performance
To investigate the effect of mental fatigue on industrial work performance, biomechanical determinants, (electro-)(psycho-) physiological measures and physical ergonomics.
- Conditions
- Healthy, Mental Fatigue, Industrial Work, Robotics
- Trial name
- NCT04721392
- Testing
- Mental fatigue (Stroop task), Control (documentary)
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Breast Neoplasms
Slow Jogging for Breast Cancer Survivors
Breast cancer survivors frequently experience persistent sleep disturbance, cancer-related fatigue, and reduced health-related quality of life after completion of primary treatment.
- Trial name
- SJBC (NCT07757763)
- Testing
- Slow Jogging Exercise, General Health and Sleep Education
- Where
- Taiwan
- Volunteers
- 104 people
- Sponsor
- Mackay Memorial Hospital
Hashimoto Thyroiditis, Thyroiditis
Effect of Photobiomodulation Therapy in Patients With Hashimoto's Thyroiditis
The standard lifelong treatment for Hashimoto's thyroiditis (HT), a chronic autoimmune disease, is levothyroxine (LT4) therapy. Despite LT4 replacement therapy, patients continue to experience persistent fatigue, deterioration in…
- Trial name
- NCT06735040
- Testing
- Photobiomodulation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Multiple Sclerosis
The Effect of Yoga on Sleep Quality, Fatigue and Physical Activity Level of Multiple Sclerosis
This randomized controlled study will be conducted to examine the effects of Yoga on Sleep, Fatigue and Physical Activity in Individuals Diagnosed with Relapsing-Remitting Multiple Sclerosis.
- Trial name
- NCT06128668
- Testing
- Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Chronic Heart Failure
Effects of Lavender Essential Oil in Patients With Chronic Heart Failure
The goal of the trial is to study the effects of lavender essential oil on sleep quality, anxiety, and fatigue in patients with chronic heart failure. The main questions it may answer are 1.
- Trial name
- NCT05862350
- Testing
- aromatherapy inhalation with lavender essential oil, aromatherapy inhalation with coconut essential oil.
- Volunteers
- 60 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University