Clinical trials: Fatigue Post Viral
Post-COVID Condition
Nutritional Intervention and Rehabilitation Treatment in Patients With Post-COVID Condition
SARS-CoV-2 is the coronavirus responsible for developing the disease known as COVID-19. Once the acute phase of the disease has passed, about 40% of the people who discharged continue to have symptoms, and of these, between 50…
- Trial name
- ARACOV-02 (NCT06063031)
- Testing
- Active
- Where
- Spain
- Volunteers
- 146 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Long COVID, Post-COVID19 Condition
Amantadine Therapy for Cognitive Impairment in Long COVID
This study will look at the effects of amantadine on cognitive function in persons with Long COVID. It will also collect specimens to study possible causes of cognitive symptoms in Long COVID, and whether any lab tests can…
- Conditions
- Long COVID, Post-COVID19 Condition, Post-Acute COVID19 Syndrome
- Trial name
- AmantadineLC (NCT06055244)
- Testing
- Amantadine
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Ohio State University
Asthenia, COVID-19
Efficacy of the Therapy With BRAINMAX® Using fMRI for the Treatment of Patients With Asthenia After COVID-19
to assess executive network using resting-state fMRI and patterns of brain activation using task fMRI with a cognitive paradigm, against the background of taking the drug in comparison with placebo in patients with post-COVID…
- Conditions
- Asthenia, COVID-19, Functional MRI, Cognitive Impairment
- Trial name
- NCT05939622
- Testing
- Structural and functional MRI, Ethyl methyl hydroxypyridine succinate + Meldonium
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Promomed, LLC
Long COVID-19 Syndrome, Chronic Fatigue Syndrome
A Multicenter, Adaptive, Randomized, doublE-blinded, Placebo-controlled Study in Participants With Long COVID-19: The REVIVE Trial
IRB approval date 14-APR-2024 and public at https://plataformabrasil.saude.gov.br/login.jsf since IURB approval Long COVID is a multi-systemic condition comprising often severe and persistent symptoms (longer than 12 weeks) that…
- Trial name
- REVIVE (NCT06128967)
- Testing
- Fluvoxamine Maleate 100 MG, Metformin Extended Release Oral Tablet
- Where
- 6 sites in Brazil
- Volunteers
- 399 people
- Sponsor
- Cardresearch
Post-Acute Sequelae of SARS-CoV-2 Infection, Long COVID
Observational Study of Intranasal IVIG in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Patients Undergoing Medical Tourism
This observational study is being conducted by Healing Hope International to collect real-world data on an emerging treatment approach for Long COVID in patients with immunodeficiency.
- Conditions
- Post-Acute Sequelae of SARS-CoV-2 Infection, Long COVID, Long COVID Fatigue, Long COVID Syndrome
- Trial name
- IVIG-LC (NCT06992401)
- Volunteers
- 50 people
- Sponsor
- Tamara C Tamas
Mixed Anxiety Depression, Diabetes Mellitus, Type 2
Concentrated Cross-disciplinary Group Intervention for Common Health Complaints (Including Post COVID-19 Fatigue)
The health care is faced by a growing challenge in the years to come: increasing age and chronic morbidity raising the costs, combined with decreased work participation.
- Conditions
- Mixed Anxiety Depression, Diabetes Mellitus, Type 2, Low Back Pain, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT05234281
- Testing
- Interdisciplincary concentrated group rehabilitation
- Where
- Norway
- Volunteers
- 1,000 people
- Sponsor
- Helse i Hardanger
Long COVID
Feasibility of Personalised Health Behaviour Coaching to Support Symptoms and Activities of Daily Living in Those With Long COVID-19.
This pilot RCT aims to assess whether a simple PA behavioural modification intervention can be delivered safely and feasibly to individuals with Long COVID suffering long standing symptoms with concerns regarding their ability to…
- Trial name
- NCT05752331
- Testing
- Physical activity behavioural modification
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Bournemouth University
Dengue, Chikungunya
Effects Of A Rehabilitation Protocol On Muscle Strength, Muscle Fatigue And Postural Control In Post-Dengue And Chikungunya Patients
Introduction: Dengue and Chikungunya arboviral diseases are considered major public health challenges in tropical regions due to high infection rates and the occurrence of musculoskeletal sequelae that impair strength, balance…
- Trial name
- NCT07600879
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 54 people
- Sponsor
- Universidade do Estado do Pará
COVID-19, Fatigue
Evaluation of an Integrative Medicine Outpatient Clinical Setting for Post-COVID-19 Patients
The study aims to identify whether a multimodal integrative naturopathy outpatient clinical concept can improve the symptoms of patients suffering from post-COVID-Syndrome. Main outcome is fatigue.
- Trial name
- TaPoCo (NCT05630378)
- Testing
- outpatient clinic with multimodal integrative medicine and naturopathy for post-COVID-19 patients, waiting group
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- Universität Duisburg-Essen
Long COVID, PASC Post Acute Sequelae of COVID 19
Brain Stimulation in Long COVID
Cognitive problems and severe fatigue are two frequently occurring symptoms in long COVID, also known as Post-Covid Condition or Post-Acute Sequelae of COVID-19 (PASC), and their causes are currently unknown.
- Conditions
- Long COVID, PASC Post Acute Sequelae of COVID 19, Post COVID-19 Condition (PCC)
- Trial name
- MALIBU (NCT07278206)
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Netherlands
- Volunteers
- 66 people
- Sponsor
- Amsterdam UMC, location VUmc
Post-Acute COVID-19 Syndrome, Biofeedback, Psychology
Prevention of Long Covid Syndrome
Biofeedback equipment is classified by the Food and Drug Administration (FDA) as medical device class II and this type of equipment/treatment has shown evidence regarding stress management in post-Covid-19 syndrome.
- Conditions
- Post-Acute COVID-19 Syndrome, Biofeedback, Psychology, Quality of Life, Depressive Symptoms
- Trial name
- NCT05793736
- Testing
- Biofeedback training, Treatment as usual
- Where
- Italy
- Volunteers
- 17 people
- Sponsor
- University of Cagliari
Post-COVID / Long-COVID, ME/CFS
Vagus Nerve Stimulation to the Ear to Improve Symptoms in Post-COVID-19 and ME/CFS
This study is testing whether a gentle electrical stimulation of a nerve in the ear, called the vagus nerve, can help reduce fatigue and improve symptoms in people with Post-COVID Syndrome or Myalgic Encephalomyelitis/Chronic…
- Trial name
- STIMPACT (NCT06968104)
- Testing
- transcutaneous vagus nerve stimulation
- Where
- Luxembourg
- Volunteers
- 48 people
- Sponsor
- University of Luxembourg
Post-COVID ME/CFS
Hyperbaric High Pressure Oxygen Therapy in Post-COVID Syndrome and ME/CFS
The objective of this observational study is to document symptom progression in 60 patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) who undergo Hyperbaric Oxygen Therapy (HBOT) following COVID or other…
- Trial name
- NCT06118138
- Testing
- Hyperbaric oxygen therapy (HBOT)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Charite University, Berlin, Germany
Post-COVID Condition, Fatigue Symptom
Study to Investigate the Efficacy of Abrocitinib in Adult Participants With Severe Fatigue From Post COVID Condition/Long COVID
The primary purpose of this phase 2a study is to compare the efficacy of abrocitinib to placebo in improving severe fatigue in non-hospitalized adults with symptomatic Post-COVID Condition (PCC) (also called Long COVID).
- Trial name
- CLEAR-LC (NCT06597396)
- Testing
- Abrocitinib
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Beth Israel Deaconess Medical Center
Post COVID-19 Condition, Cognitive Impairment
Cognitive Impairment and Fatigue After Mild to Moderate COVID-19
The primary aim of the project is to map fatigue, cognitive and visual dysfunctions and possible underlying pathophysiological mechanisms in persons with long-term symptoms after a mild to moderate COVID-19 infection.
- Conditions
- Post COVID-19 Condition, Cognitive Impairment, Fatigue, Mental
- Trial name
- NCT06042530
- Testing
- Neuropsychological investigation, Optometric investigation, Magnetic Resonance Imaging
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Danderyd Hospital
Post Acute Sequelae of SARS CoV 2 Infection, Obstructive Sleep Apnea
Predictors of Post-COVID-19 Clinical and Cognitive Consequences
The CDC describes Post-acute sequelae of SARS-COV-2 infection (PASC) for the wide range of physical and mental health consequences experienced by some patients.
- Trial name
- SCLC (NCT06291870)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
ME/CFS, Post-COVID ME/CFS
Immunoadsorption in Patients With Chronic Fatigue Syndrome Including Patients With Post-COVID-19 CFS
The goal of this clinical trial is to learn about the effectiveness of repeated immunoadsorption intervention in patients with chronic fatigue syndrome (CFS) including patients with post-acute COVID-19 CFS (PACS-CFS).
- Trial name
- NCT05710770
- Testing
- Immunoadsorption
- Where
- Germany
- Volunteers
- 66 people
- Sponsor
- Charite University, Berlin, Germany
Postacute Sequelae of Sars-CoV-2, Post-Acute COVID-19 Syndrome
Transcutaneous Electrical Nerve Stimulation (TENS) in Patients With Postacute Sequelae of Sars-CoV-2
The purpose of the pilot study is to examine acceptability and proof of concept effectiveness of a wireless TENS technology to address PASC associated FM.
- Conditions
- Postacute Sequelae of Sars-CoV-2, Post-Acute COVID-19 Syndrome, Widespread Chronic Pain, Fatigue Syndrome, Chronic
- Trial name
- NCT05200858
- Testing
- TENS - high-dose, TENS - low-dose
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Baylor College of Medicine
Long COVID, Fatigue
Long COVID-19 Fatigue and Obstructive Sleep Apnea
Identify the relationship of obstructive sleep apnea (OSA) prevalence with post-COVID-19 fatigue that remains at least six months after acute disease
- Conditions
- Long COVID, Fatigue, Obstructive Sleep Apnea of Adult
- Trial name
- PostCoV2OSA (NCT05290350)
- Testing
- OSA
- Where
- 12 sites in Portugal
- Volunteers
- 300 people
- Sponsor
- Centro Hospitalar Universitario do Algarve
COVID-19
Mechanisms Underlying Long-term Fatigue and Exercise Intolerance Following COVID-19
The MEXICO study is an observational study that aims to identify underlying mechanisms contributing to exercise intolerance in the presence of persistent COVID-19 symptoms (Long COVID).
- Trial name
- MEXICO (NCT04914754)
- Where
- United Kingdom
- Volunteers
- 51 people
- Sponsor
- University College, London