Clinical trials: Fatigue Symptom
Breast Cancer, Cognitive Dysfunction
Reducing Breast Cancer-related Fatigue and Improving Cognition With Non-Invasive Brain Stimulation
This study will test the preliminary efficacy of transcranial direct current stimulation (tDCS) to improve fatigue and cognition in women with a history of breast cancer and persistent fatigue.
- Conditions
- Breast Cancer, Cognitive Dysfunction, Fatigue
- Trial name
- NCT03143894
- Testing
- tDCS
- Where
- 3 sites in United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cardiac Arrest
Comparison of Bystander Fatigue and CPR Quality When Using Two Different CPR Ratios.
STUDY OBJECTIVES The overall goal of this study is to compare bystander fatigue and CPR quality after 5 minutes of the new 30:2 versus the old 15:2 chest compression to ventilation International Resuscitation Guidelines, in a…
- Trial name
- NCT00380757
- Testing
- bystander CPR using 30:2 ratio vs 15:2 ratio
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Menopause
Effect of Nuvigil on Fatigue
The purpose of this study is to determine if armodafinil improves quality of life and is an effective treatment of fatigue in symptomatic perimenopausal and postmenopausal women.
- Trial name
- NCT01460628
- Testing
- Armodafinil
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Fatigue, Aging
Role of Skeletal Muscle Nitric Oxide Production in Age-related Fatigue and Fatigability
This is a pilot study funded by the National Institutes of Health. In this project, we will investigate the potential effect of skeletal muscle nitric oxide (NO) production on muscle strength and physical function in older…
- Trial name
- NCT01059994
- Testing
- Sildenafil
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Heart Failure
Premature Fatigue in Veterans With Heart Failure: Neuronal Influences
A hallmark of patients with heart failure (HF) is premature fatigue which impairs their quality of life and depicts a major source of morbidity.
- Trial name
- NCT02209610
- Testing
- Electrical and Magnetic Nerve Stimulators, Intrathecal Fentanyl
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Advanced Cancers
The Effects of Thalidomide on Symptom Clusters
The goal of this clinical research study is to learn if thalidomide can improve symptoms such as pain, fatigue,anxiety, poor appetite, depression, and sleep problems in patients with advanced cancer.
- Trial name
- NCT00379353
- Testing
- Thalidomide
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- M.D. Anderson Cancer Center
Heart Failure
Acute Effects of Beet Juice Consumption on Exercise Capacity in Heart Failure
The purpose of this project will be to determine whether consumption of beet juice concentrate prior to exercise may acutely improve exercise tolerance in patients with heart failure.
- Trial name
- NCT01946542
- Testing
- beet juice concentrate
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Jason Allen, Ph.D.
Colorectal Cancer, Depression
Escitalopram in Treating Depression in Patients With Advanced Lung or Gastrointestinal Cancer
RATIONALE: Escitalopram may help improve depression and quality of life in patients with advanced lung or gastrointestinal cancer.
- Conditions
- Colorectal Cancer, Depression, Esophageal Cancer, Extrahepatic Bile Duct Cancer
- Trial name
- NCT00387348
- Testing
- escitalopram oxalate
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Massachusetts General Hospital
Cancer
The Effect of a Mediterranean Diet Intervention on Cancer-related Fatigue and Mitochondrial Function During Chemotherapy
This study will assess the feasibility of delivering an 8-week Mediterranean Diet intervention as well as the intervention's preliminary efficacy on cancer-related fatigue among patients undergoing chemotherapy, compared to usual…
- Trial name
- DANICA (NCT04534738)
- Testing
- Mediterranean Diet
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- University of Rochester
Metastatic Breast Cancer
Telephone Support for Metastatic Breast Cancer Patients
This trial tests telephone-based Acceptance and Commitment Therapy (ACT), a type of psychotherapy, to reduce fatigue interference with activities, mood, and cognition in metastatic breast cancer (MBC) cancer patients.
- Trial name
- NCT03998618
- Testing
- Acceptance and Commitment Therapy, Education/Support
- Where
- 3 sites in United States
- Volunteers
- 250 people
- Sponsor
- Indiana University
Leukemia, Hodgkin Lymphoma
Yoga to Alleviate Fatigue, Anxiety and Pain in Adolescents During Treatment for Lymphoma or Leukemia
Researchers at St. Jude Children's Research Hospital want to investigate the feasibility of a yoga intervention for adolescents receiving treatment for lymphoma or leukemia.
- Conditions
- Leukemia, Hodgkin Lymphoma, Lymphoma, Non-Hodgkin's
- Trial name
- NCT02473523
- Testing
- PedsQL Cancer Module, PedsQL Multidimensional Fatigue Scale, Biodex System 3 Dynamometer
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- St. Jude Children's Research Hospital
Multiple Sclerosis
American Ginseng Treatment for Multiple Sclerosis Related Fatigue
This research project will determine the safety and tolerability of ginseng in subjects with MS and will gather preliminary data on the efficacy of ginseng vs placebo for the treatment of MS fatigue.
- Trial name
- NCT00754832
- Testing
- American ginseng extract HT-1001
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Oregon Health and Science University
Head And Neck Cancer, Fatigue
Single Agent Armodafinil for Patient-Reported Fatigue Following Radiation Therapy for Head and Neck Cancer
The goal of this clinical research study is to learn if armodafinil can reduce fatigue and other common symptoms in patients that have received treatment for head and neck cancer.
- Trial name
- NCT01330446
- Testing
- Armodafinil, Questionnaires
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer
Alternative Exercise Program to Improve Skeletal Muscle Function and Fatigue in Cancer Survivors
Exercise training has beneficial effects in cancer survivors to minimize some of the side effects of cancer and its treatment and improve long-term prognosis, but there are numerous hurdles for individuals diagnosed with, and…
- Trial name
- NCT02739620
- Testing
- Neuromuscular electrical stimulation
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Vermont
Multiple Sclerosis, Relapsing-Remitting
Light Therapy as Treatment for Fatigue in Multiple Sclerosis
This prospective study will randomize 1:1 people living with multiple sclerosis-associated fatigue to one of two spectra of light therapy.
- Trial name
- NCT03060759
- Testing
- Light Therapy box
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Massachusetts General Hospital
Advanced Cancer
Testosterone Replacement for Fatigue in Male Hypogonadic Advanced Cancer Patients
The goal of this clinical research study is to learn if and how testosterone replacement therapy may affect fatigue in males with advanced cancer and low testosterone levels.
- Trial name
- NCT00965341
- Testing
- Testosterone
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- M.D. Anderson Cancer Center
Chronic Neuromuscular Pain
HRV Biofeedback in Pain Patients
Pain initiates a stress response that increases sympathetic output and leads to autonomic imbalance. Heart rate variability (HRV) is a easy to perform, valid measure of autonomic function.
- Trial name
- HRVB-PP (NCT02426476)
- Testing
- active heart rate variability biofeedback training
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- VA Office of Research and Development
Systemic Lupus Erythematosus, Lupus
Aerobic Exercise in Women With Systemic Lupus Erythematosus
Background: As many as 1.5 million Americans are living with systemic lupus erythematosus (Lupus). Lupus makes people very tired. It also makes it hard for people to be physically active.
- Conditions
- Systemic Lupus Erythematosus, Lupus, Autoimmune Disease, Rheumatic Disease
- Trial name
- NCT03186794
- Testing
- Treadmill exercise training
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Attention, Memory
Polyunsaturated Fatty Acids (PUFA) Status and Cognitive Function in Healthy Young Adults
To date, the relationship between omega-3 polyunsaturated fatty acids (n-3 PUFAs) in cognitively intact individuals has only been examined in a limited number of studies; it is at present unknown whether supplementation with n-3…
- Conditions
- Attention, Memory, Mood, Mental Fatigue
- Trial name
- NCT01075958
- Where
- United Kingdom
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Fatigue
Armodafinil in Reducing Cancer-Related Fatigue in Patients With High Grade Glioma
This randomized phase III trial studies armodafinil to see how well it works in reducing cancer-related fatigue in patients with high grade glioma. Armodafinil may help relieve fatigue in patients with high grade glioma.
- Trial name
- NCT01781468
- Testing
- armodafinil 150 mg, armodafinil 250 mg
- Where
- 365 sites in United States
- Volunteers
- 328 people
- Sponsor
- Alliance for Clinical Trials in Oncology