Clinical trials: Fatigue in Multiple Sclerosis
Multiple Sclerosis
Effects of Head and Neck Cooling and Heating on Fatigue in Multiple Sclerosis and Healthy Men
Local head and neck cooling strategies can help reduce multiple sclerosis-related fatigue, while heating can exacerbate heat-related fatigue.
- Trial name
- NCT06370403
- Testing
- Cooling of the head and neck, Heating of the head and neck
- Where
- Lithuania
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Multiple Sclerosis (MS), Fatigue
Increasing Physical Activity for Adults With Multiple Sclerosis (MS)
This study aims to advance the scientific understanding and potential future implementation of physical activity promotion by testing the efficacy of a phone-based app for increasing activity in insufficiently active patients…
- Conditions
- Multiple Sclerosis (MS), Fatigue, Physical Inactivity
- Trial name
- NCT06270641
- Testing
- ExerciseRx intervention
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Washington
Multiple Sclerosis
Evaluation of Muscle Oxidative Capacity Relationship With Muscular Endurance, Fatigue (Multiple Sclerosis).
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system. It is characterized by different progressive forms with periods of flare-ups interspersed with phases of remission.
- Trial name
- OXYSEP (NCT06083194)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Multiple Sclerosis
Cardiovascular Fitness of Patients With Multiple Sclerosis, Effect of Exercise on Fatigue and Depression
This study is focused on patients with multiple sclerosis (MS), their cardiovascular fitness, and the effect of combined controlled training on the perception of fatigue, the development of depression, and quality of life in the…
- Trial name
- NCT05671588
- Testing
- Controlled combined exercise group, Conventional rehabilitation
- Where
- Czechia
- Volunteers
- 70 people
- Sponsor
- University Hospital Ostrava
Multiple Sclerosis
RIPC on Activity, Fatigue and Gait in MS
This study evaluates whether Remote Ischaemic Preconditioning (RIPC) can improve activity, gait and fatigue in people with Multiple Sclerosis. Half the participants will receive RIPC, the other half will receive a sham treatment.
- Trial name
- MSIPC-2 (NCT03967106)
- Testing
- Ischaemic Preconditioning
- Where
- United Kingdom
- Volunteers
- 92 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Multiple Sclerosis
MS Spinal Mobilisation Study
The objective of the study is to measure the effect of a spinal mobilisation intervention on para-spinal muscle tissue quality, functional balance measures, pain and fatigue in people with multiple sclerosis.
- Trial name
- NCT05090709
- Testing
- Spinal Mobilisation Intervention, General Massage
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Edinburgh Napier University
Multiple Sclerosis, Fatigue
The Effect of the Nurses Support Program on Fatigue in MS Patient
The research will be carried out as a randomized controlled experimental study to examine the effect of a nursing support program supported by a Web-based education program on the management of fatigue symptoms of patients who…
- Conditions
- Multiple Sclerosis, Fatigue, Sleep Hygiene, Quality of Life
- Trial name
- NCT06166043
- Testing
- NURSE FOLLOW-UP PROGRAM SUPPORTED WITH WEB-BASED EDUCATION
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University - Cerrahpasa
Multiple Sclerosis, Fatigue
Amantadine and Transcranial Magnetic Stimulation for Treating Fatigue in Multiple Sclerosis
Multiple Sclerosis (MS) is the most frequent cause of non-traumatic disability in people under 55 years of age. Fatigue is the most frequent and disabling symptom in the disease, and for which there is no effective treatment.
- Trial name
- FETEM (NCT05809414)
- Testing
- Transcranial Magnetic Stimulation, Amantadine Hydrochloride 100 mg (milligrams) Oral Capsule
- Where
- 4 sites in Spain
- Volunteers
- 144 people
- Sponsor
- Hospital San Carlos, Madrid
Multiple Sclerosis
Role of Individualized Versus Traditional Exercise in Combating Fatigue
The objective of this project will be to characterise the benefits of an exercise programme adapted to each individual's abilities compared to a traditional exercise programme with the aim of reducing perceived fatigue and…
- Trial name
- REEN-SEP (NCT04796272)
- Testing
- Adapted and individualized physical training program, traditional training program
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Multiple Sclerosis
The Effect Of Proprioceptive Neuromuscular Facilitation Techniqueson in Patients With Multiple Sclerosis
The aim of this study is to examine the effects of PNF techniques on pain, motor function, fatigue and quality of life.
- Trial name
- NCT06102148
- Testing
- PNF Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Nilay Comuk Balci
Asthma, Atrial Fibrillation
The Living With a Long-Term Condition Study
Psychological distress (anxiety and depression) is common in and experienced differently by people living with long-term health conditions (LTCs).
- Conditions
- Asthma, Atrial Fibrillation, Cancer, Cerebrovascular Disorders
- Trial name
- LTC (NCT06072287)
- Testing
- Living with LTC Questionnaire
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- King's College London
Multiple Sclerosis
Effect of Aerobic Training vs Balance Training on Fatigue Symptom in Multiple Sclerosis Patient (FATI-gate)
Fatigue and impaired balance frequently affect patients with Multiple Sclerosis (MS). This is an open, prospective randomised crossover trial aimed at clarifying whether an improvement in balance control after balance training…
- Trial name
- FATI-gate (NCT06051019)
- Testing
- Aerobic training, Balance training
- Volunteers
- 39 people
- Sponsor
- Istituto Auxologico Italiano
Multiple Sclerosis
Fatigue and Sleep Quality in Multiple Sclerosis Patients
This study was planned to examine the effect of reiki application on fatigue and sleep quality in patients with multiple sclerosis.
- Trial name
- NCT05456464
- Testing
- Reiki
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Sabahattin Zaim University
Multiple Sclerosis
Evaluation of Natalizumab for thE Relief of MS Associated FatiGue
This study aims to study the effects of TYSABRI® treatment on fatigue and cognition in patients with relapsing forms of MS.
- Trial name
- ENER-G (NCT00464074)
- Where
- 31 sites in United States, Puerto Rico
- Volunteers
- 89 people
- Sponsor
- Biogen
Multiple Sclerosis
Prediction of Non-motor Symptoms in Fully Ambulatory MS Patients Using Vocal Biomarkers
The investigator will set up a study evaluating vocal biomarkers in people with MS in order to identify persons with non-motor symptoms: depression, cognitive deterioration, and fatigue.
- Trial name
- COMMITMENT (NCT05561621)
- Testing
- Voice analysis
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Fatigue, Functionality
The Effect of the Level of Hand Fatigability on Multiple Sclerosis on General Fatigue and Functionality
The objective of this study is to investigate the effect of the level of hand fatigability on general fatigue and functionality by comparing Relapsing-Remitting Multiple Sclerosis individuals with age and sex-matched healthy…
- Conditions
- Fatigue, Functionality, Multiple Sclerosis, Dexterity
- Trial name
- NCT05880745
- Testing
- Nine-Hole Peg Test (NHPT)
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Relapsing Remitting Multiple Sclerosis, Secondary-progressive Multiple Sclerosis
Improving Cognitive Aptitudes With tDCS in Patients With Multiple Sclerosis
Noninvasive brain stimulations (NIBS) will be used in MS patients with cognitive impairments to enhance their cognitive aptitudes.
- Conditions
- Relapsing Remitting Multiple Sclerosis, Secondary-progressive Multiple Sclerosis, Cognitive Deficits, Motor Deficits
- Trial name
- MScog-tDCS (NCT02266121)
- Testing
- tDCS
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital of Mont-Godinne
Multiple Sclerosis, Fatigue
MitoQ for Fatigue in Multiple Sclerosis
The purpose of this study is to determine whether MS patients who receive Oral mitoquinone (MitoQ) have less fatigue than those receiving a placebo.
- Trial name
- MS (NCT03166800)
- Testing
- Mitoquinone
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Oregon Health and Science University
Multiple Sclerosis
Dalfampridine in Egyptian Patients With Multiple Sclerosis
The only approved treatment for impaired ambulation in MS is Dalfampridine (also known as fampridine, 4-aminopyridine, 4-AP). Fampridine penetrates the blood-brain barrier and improves impaired axonal conduction by selectively…
- Trial name
- NCT05730738
- Testing
- Dalfampridine ER, 10 Mg Oral Tablet, Extended Release
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Falls, Motor Imagery
The Effect of Motor Imagery on Balance in Persons With Multiple Sclerosis
This study will investigate if the use of motor imagery to practice a balance task is as effective as physically practicing balance tasks as measured by the Berg Balance Scale (BBS) in persons with MS.
- Conditions
- Falls, Motor Imagery, Multiple Sclerosis, Balance
- Trial name
- NCT05615207
- Testing
- Motor Imagery as compared to physical practice for balance tasks
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Dominican University New York