Clinical trials: Fear, open to volunteers
Pregnancy, Anxiety
Mandala Coloring in Late Pregnancy
Anxiety, depression and poor sleep are common in the last months of pregnancy and often occur together. Medication options during pregnancy are limited, so simple, safe non-drug methods are needed.
- Conditions
- Pregnancy, Anxiety, Depression, Psychological Stress
- Trial name
- NCT07906743
- Testing
- Mandala Coloring Group
- Where
- Turkey (Türkiye)
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Fidan Balkaya
Chronic Pain, Musculoskeletal Pain
Multicomponent Exercise and Pain Science Education for Fall Prevention in Older Adults With Chronic Musculoskeletal Pain (MovePainFall)
Chronic musculoskeletal pain is common in older adults and is associated with reduced mobility, loss of function, poorer quality of life, fear of movement, fear of falling and a higher risk of falls.
- Conditions
- Chronic Pain, Musculoskeletal Pain, Accidental Falls, Fear of Falling
- Trial name
- MovePainFall (NCT07889024)
- Testing
- MovePainFall multicomponent exercise programme, Pain science and fall-prevention education
- Where
- Portugal
- Volunteers
- 40 people
- Sponsor
- Instituto Politécnico de Bragança
Procedural Pain, Pain-related Fear
Distraction Cards Versus Emotion-Regulation Toy Squeezing During Intramuscular Vaccination in Preschool Children
This single-center, parallel-group, randomized experimental study will compare the effects of two active non-pharmacological interventions - distraction-card use and emotion-regulation toy squeezing - on procedural pain and…
- Trial name
- NCT07669961
- Testing
- Distraction-Card Group, Emotion-Regulation Toy-Squeezing Group
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Mersin University
Diabetes (DM), Diabetes Mellitus
Changes in Person-reported Outcomes and Behavior Using the Accu-Chek SmartGuide CGM and Predict App
The goal of this controlled pre-post-trial is to test the Accu-Chek SmartGuide continuous glucose monitoring (CGM) system and whether its predictive features provide additional benefits for adults with type 1 diabetes or insulin…
- Conditions
- Diabetes (DM), Diabetes Mellitus, Diabetes Mellitus Type 2, Diabetes Mellitus Type 1
- Trial name
- NCT07814508
- Testing
- SmartGuide CGM with Predictive Features
- Where
- Germany
- Volunteers
- 89 people
- Sponsor
- FIDAM RDC
Fear of Childbirth, Pregnancy
Mindfulness Psychoeducation Based on Transtheoretical Model for Fear of Childbirth
Childbirth is a significant life event with important physical and psychological effects on pregnant women. Due to uncertainty during pregnancy, many women experience fear of childbirth.
- Trial name
- NCT07624253
- Testing
- Mindfulness-Based Psychoeducation
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Nigde Omer Halisdemir University
Social Anxiety Disorder, Social Fear
Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)Therapy for Social Anxiety Disorder
This clinical trial aims to evaluate the efficacy and safety of transcutaneous auricular vagus nerve stimulation (taVNS) in patients with social anxiety disorder (SAD).
- Trial name
- taVNS (NCT07772401)
- Testing
- taVNS
- Where
- 2 sites in China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Fear
Opioids and Social Support Enhanced Extinction Effects
University of California, Los Angeles researchers will recruit healthy participants (age 18-35) to participate in a study examining whether the administration of naltrexone, an opioid antagonist, eliminates the ability of social…
- Trial name
- SSO (NCT04166071)
- Testing
- Naltrexone
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Anxiety, Fear
The Effect of a Stress Ball Applied Before Retrograde Intrarenal Surgery
This study was designed as a randomized controlled trial to determine the effect of a stress ball applied before retrograde intrarenal surgery on patients' anxiety levels, surgical fear, and hemodynamic parameters.
- Trial name
- Stressball (NCT07507656)
- Testing
- stress ball
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Mersin University
Anxiety, Fear
Effectiveness of Multisensoral Nature-based Intervention in Hospitalized Children During Venous Blood Sampling
This randomized controlled trial (RCT) study aims to evaluate the effectiveness of multisensoral nature-based intervention compare to standard care in relieving anxiety, fear and pain in hospitalized child aged 5 to 9 years and…
- Conditions
- Anxiety, Fear, Pain, Satifaction
- Trial name
- NCT05494684
- Testing
- Multisensoral Nature-based Intervention
- Where
- Finland
- Volunteers
- 106 people
- Sponsor
- University of Oulu
Anxiety and Fear, PTSD
K08 VR Fear Conditioning
The goal of this clinical trial is to learn how people respond to fear-related experiences in a virtual reality (VR) environment.
- Conditions
- Anxiety and Fear, PTSD, Veteran
- Trial name
- NCT07216222
- Testing
- Deep Brain Stimulation
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Injection Fear, Injection Pain Prevention
Does Ethyl Chloride Spray Work?
A procedure frequently performed by orthopaedic providers is the administration of corticosteroid injections for the management of various soft tissues and joint-related conditions, such as osteoarthritis, tendinitis, carpal…
- Conditions
- Injection Fear, Injection Pain Prevention, Injection Complication
- Trial name
- NCT06651788
- Testing
- Ethyl Chloride, Cold Saline Spray
- Where
- United States
- Volunteers
- 246 people
- Sponsor
- University of Chicago
Fear of Childbirth, Childbirth-Related Anxiety
Effectiveness of Gestaverso Virtual Reality Birth Preparation in Women With Previous Negative Birth Experiences
A previous negative childbirth experience can increase fear and anxiety about giving birth again. This study aims to determine whether Gestaverso, a virtual reality-based childbirth preparation program, can help reduce fear of…
- Trial name
- Gestaverso (NCT07846306)
- Testing
- Gestaverso, Control group
- Volunteers
- 124 people
- Sponsor
- Fundación de investigación HM
Preoperative Anxiety, Fear
Virtual Reality for Pediatric Perioperative Preparation
This pilot randomized controlled trial will evaluate whether a virtual reality (VR) preparation program can improve the perioperative experience of children aged 3 to 12 years undergoing elective surgery.
- Conditions
- Preoperative Anxiety, Fear, Pediatric Surgery, Preoperative Care
- Trial name
- NCT07650695
- Testing
- NixiKit Virtual Reality Preparation, Standard Nursing Preoperative Preparation
- Where
- Spain
- Volunteers
- 56 people
- Sponsor
- Fundación de investigación HM
Osteoarthritis (OA) of the Knee, Fear of Needles
Pain Perception During Intra-Articular Knee Joint Injection: What is the Effect of Needle Gauge and the Use of Ethyl Chloride?
This study aims to investigate factors that affect the subjective experience of pain during and after intra-articular knee joint injection of steroids by comparing needle gauge size (22 G vs 25 G needles), as well as the presence…
- Trial name
- NCT06865170
- Testing
- 25 gauge needle, 22 gauge needle, +/- Ethyl Chloride Topical Aerosol Anesthetic
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Chronic Pain, Kinesiophobia (Fear of Movement)
Virtual Reality for Pain and Well-Being in Older Adults
Chronic pain is common among adults aged 65 and older and can reduce mobility, independence, mood, and quality of life. Many older adults also develop a fear of movement because they worry that physical activity will increase…
- Trial name
- VitaMove (NCT07607899)
- Testing
- Virtual Reality-Supported Rehabilitation, Usual Care
- Where
- 2 sites in Canada
- Volunteers
- 24 people
- Sponsor
- Laval University
Blood Sampling, Child, Only
Two Different Therapeutic Interventions Applied During Blood Sampling in Children
This research is a three-group, randomized controlled experimental study designed to determine the effect of two different therapeutic interventions applied during blood sampling on pain, anxiety, and fear levels in children aged…
- Conditions
- Blood Sampling, Child, Only, Pain, Fear
- Trial name
- NCT07731347
- Testing
- experimental group, experiment group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Igdir University
Fear of Cancer Progression
A Brief Psychological Intervention for Carer Fear of Cancer Progression
This study aims to evaluate the feasibility and acceptability of the Conquer Fear Carer Brief, a three-session psychological intervention targeting fear of cancer progression among caregivers of patients with metastatic prostate…
- Trial name
- NCT07752992
- Testing
- Conquer Fear Carer Brief
- Where
- Denmark
- Volunteers
- 14 people
- Sponsor
- University of Aarhus
Anxiety, Fear Extinction
Uncovering Neurocognitive Mechanisms and Enhancement of Exposure-based Fear Learning With Cognitive Training
Anxiety disorders remain are among the most prevalent psychiatric conditions and are associated with negative outcomes spanning poor health to increased suicide risk.
- Trial name
- NCT07805070
- Testing
- Cognitive training
- Volunteers
- 120 people
- Sponsor
- University of California, San Diego
Anxiety and Fear-Related Disorders
Personalized and Accelerated Transcranial Magnetic Stimulation for Treatment-resistant Anxiety Related Disorders
This proposal seeks to carry out an open-label single arm study to examine the neurobehavioral changes induced by personalized, causal network mapping guided accelerated intermittent theta burst stimulation (aiTBS) in patients…
- Trial name
- I2Start (NCT07801391)
- Testing
- Individually Neuronavigated accelerated intermittent theta burst stimulation with MagPro X100
- Where
- Singapore
- Volunteers
- 24 people
- Sponsor
- National University Hospital, Singapore
Fear Extinction
Amygdala-Prefrontal in Fear Extinction
The goal of this clinical trial is to understand how brain circuits involving the amygdala and prefrontal cortex contribute to fear learning and extinction.
- Trial name
- NCT07800455
- Testing
- Direct intracranial electrical stimulation, Fear conditioning
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Washington University School of Medicine