Clinical trials: Fear Extinction
Healthy Participants
Cannabinoid Control of Fear Extinction Neural Circuits in Humans
The goal of the current proposal is to investigate the effects of a cannabinoid drug on the memory of extinguished fear in humans and the brain circuitry important for the recall of extinction learning.
- Trial name
- NCT02472847
- Testing
- Dronabinol
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Post-Traumatic Stress Disorder
Cannabinoid Control of Fear Extinction Neural Circuits in Post-traumatic Stress Disorder
The goal of this study is to look at how a type of drug called cannabinoids are related to the processing of fear signals, the experience of emotions and fear, and the pattern of activity in the brain that is involved in these…
- Trial name
- NCT02069366
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Stress Related Disorder, Anxiety
Modulation of Fear Extinction Processes Using Transcranial Electrical Stimulation
The aim of this study is to examine the effects of transcranial electrical stimulation on processes associated with fear extinction in healthy humans.
- Trial name
- NCT02723188
- Testing
- DC stimulation (1.5 milliampere, 20 minutes), AC stimulation (1.5 milliampere,1.5 Hertz frequency)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Stress Disorders, Posttraumatic
Veteran Stress and Learning Study
This is a research study examining the use of two medications, Hydrocortisone and D-Cycloserine, compared to an inactive substance (placebo), on their ability to reduce fear responses and memory of fear in Veterans with symptoms…
- Trial name
- VSL (NCT00674570)
- Testing
- Hydrocortisone, D-Cycloserine
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder, Anxiety Disorder
Pilot Study of Pharmaceutical and Behavioral Interventions to Treat Anxiety Disorders
The aim of this project is to create fear conditioning paradigm within which the relative strengths of various novel pharmacological and behavioral interventions can be tested.
- Trial name
- NCT01631682
- Testing
- Propranolol, Reactivation, Mifepristone
- Where
- United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital