Clinical trials: Fear of Cancer Recurrence, open to volunteers
Breast Cancer, Ovarian Cancer
Study of Psilocybin Assisted Psychotherapy to Address Fear of Recurrence
The goal of this clinical trial is to test whether psilocybin along with therapy in women with early breast cancer and ovarian cancer in remission can improve their fear of recurrence.
- Trial name
- NCT06430541
- Testing
- Psilocybin
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
Fear of Cancer Recurrence, Cancer
Implementation and Evaluation of a Fear of Cancer Recurrence Screening, Referral and Management Program
The purpose of this study is to evaluate the process and outcomes of an implementation program designed to implement fear of cancer screening, referral and management into routine cancer care clinics, using a stepped-wedge…
- Trial name
- NCT06181344
- Testing
- FCR screening and referral program
- Where
- 2 sites in Hong Kong
- Volunteers
- 1,980 people
- Sponsor
- The University of Hong Kong
Breast Cancer
The Effect of a Multi-modal Program on Fear of Cancer Recurrence in Breast Cancer Patients
The goal of this clinical trial is to learn if MMP intervention can alleviate FCR , breast cancer symptoms and social support among breast cancer patients.
- Trial name
- NCT06883877
- Testing
- Multi-Modal Program (MMP), Routine care
- Volunteers
- 84 people
- Sponsor
- LIU WEIMIN
Cancer, Fear of Cancer Recurrence
The Effect of a Stepped-care Metacognition-based Intervention on Managing Fear of Cancer Recurrence
A sequential multiple-assignment randomized controlled trial (SMART) will be used to assess the effect of an adaptive stepped-care intervention on FCR in cancer survivors with subclinical levels of fear of cancer recurrence.
- Trial name
- NCT06181331
- Testing
- eConquerFear, eHealthMaintenance, ConquerFear
- Where
- Hong Kong
- Volunteers
- 300 people
- Sponsor
- The University of Hong Kong
Fear of Cancer Recurrence, Cancer Survivors
Fighting the Fear of Cancer Recurrence in Cancer Survivors: A Pilot Study on the Effectiveness of Metacognitive Therapy
This study aims to evaluate the effectiveness of metacognitive therapy (MCT) in reducing fear of cancer recurrence (FCR) among cancer survivors. With advances in cancer treatment, more patients are surviving cancer.
- Conditions
- Fear of Cancer Recurrence, Cancer Survivors, Psychological Distress
- Trial name
- MCT-FCR (NCT07500168)
- Testing
- Metacognitive Therapy, Relaxation Therapy
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Koo Foundation Sun Yat-Sen Cancer Center
Cognitive Behavioral Therapy
Fear of Recurrence and Stopping Immunotherapy
The study includes participants experiencing distress with regard to stopping immunotherapy and will utilize cognitive-behavioral therapy to reduce fear of recurrence, depression, and anxiety and improve quality of life.
- Trial name
- NCT04761328
- Testing
- cognitive behavioral therapy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Pittsburgh
Fear of Cancer Recurrence, Cancer Survivorship
Acceptance and Commitment Therapy (ACT) Versus Cognitive Behavioural Therapy (CBT) for Fear of Cancer Recurrence (FCR) in Cancer Survivors and Their Spouses
Fear of cancer recurrence (FCR) is one of the most significant psychological burdens faced by cancer survivors. FCR describes the fear, worry, or concern relating to the possibility that cancer will come back or progress, and is…
- Trial name
- CARE-Pilot (NCT07749560)
- Testing
- ACT couple intervention, CBT couple intervention
- Volunteers
- 128 people
- Sponsor
- University Center of Tumor Diseases, Frankfurt University Hospital
Early-stage Breast Cancer, Fear of Cancer Recurrence
Psilocybin FCR Early-Stage Breast Cancer
This trial is designed to evaluate efficacy and psychological mechanisms of single-dose psilocybin-assisted psychotherapy (PAP) to treat fear of cancer recurrence (FCR), psychiatric (anxiety, depression) distress and…
- Conditions
- Early-stage Breast Cancer, Fear of Cancer Recurrence, Anxiety, Depression
- Trial name
- NCT07909408
- Testing
- Psilocybin 25 mg, Psilocybin 5 mg
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Fear of Cancer Recurrence, Renal Cell Carcinoma (Kidney Cancer)
Patient-partnered Research in Investigating Fear of Cancer Recurrence in Kidney Cancer
The goal of this observational study is to gather real-world information about Fear of Cancer Recurrence (FCR) following surgery in patients with renal cell carcinoma (RCC) and their partners/spouses by 1) establishing a panel…
- Trial name
- PP-RECURK (NCT07234656)
- Testing
- Phase 1: Establishment of a patient-partner panel, Phase 2: Feasibility testing of FCR questions, mode of administration and timing for investigating Fear of Cancer Recurrence
- Where
- 3 sites in Denmark
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Brigitta Rasmussen Villumsen
Barrett's Esophagus, Esophageal Adenocarcinoma
A Study of Barrett's Esophagus Patients to Investigate Quality of Life and Fear of Cancer, and Optimize a Risk Model Based on Biomarkers and New Technologies to Better Predict the Development of Cancer
This study serves, in part, to prepare for a future large cohort study. The goal of the study is: 1. The collection of various tissue samples (blood, biopsies and "esophageal brushes") and their analysis. 2.
- Trial name
- Endeavor-1 (NCT06523374)
- Testing
- Endoscopic brush cytology
- Where
- 9 sites in Belgium, Denmark and 4 more
- Volunteers
- 50 people
- Sponsor
- University Hospital, Antwerp
Fear of Cancer Recurrence
Targeting Fear of Cancer Recurrence in Cancer Survivors: Evaluation of Internet-Based Emotional Freedom Techniques and Internet-Based Mindfulness Meditation as Intervention Strategies
In this trial, the investigators introduce two internet-based psychological methods to meet the currently unmet medical need to cope with Fear of Cancer Recurrence (FCR) beyond the acute phase of cancer treatment: internet-based…
- Trial name
- REMOTE (NCT06175208)
- Testing
- Emotional Freedom Techniques, Mindfulness Meditation
- Where
- 11 sites in Belgium
- Volunteers
- 339 people
- Sponsor
- General Hospital Groeninge
Fear of Cacer Recurrence in Cancer Survivorws
Cancer Survivors' Fear of Cancer Recurrence
The purpose of this study is to develop and evaluate the tailored support for the fear of cancer recurrence in breast, head and neck, colon-rectal or prostate cancer survivors.
- Trial name
- MHPII (NCT07542821)
- Testing
- psycological cognitive training, Healthy lifestyle, education
- Volunteers
- 150 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Lung Neoplasms, Acceptance and Commitment Therapy
Construction and Preliminary Evaluation of Dyadic Acceptance and Commitment Therapy for Couples With Fear of Lung Cancer Recurrence
The goal of this clinical trial is to develop a simple, scientific, effective, and culturally adapted dyadic Acceptance and Commitment Therapy (ACT) intervention program (the ADAPT program) targeting fear of cancer recurrence…
- Conditions
- Lung Neoplasms, Acceptance and Commitment Therapy, Spouses
- Trial name
- NCT07588347
- Testing
- Dyadic Acceptance and Commitment Therapy (ACT) for lung cancer patients and their spouse caregivers addressing FCR and routine care, routine care
- Volunteers
- 72 people
- Sponsor
- Feifei Huang
Breast Cancer, Breast Cancer Survivors
Psychoeducation and Well-Being After Breast Cancer
This randomized controlled trial evaluates the effectiveness of a web-based psychoeducation program on psychological well-being and quality of life in breast cancer survivors who completed active treatment at least one year…
- Conditions
- Breast Cancer, Breast Cancer Survivors, Breast - Female, Psycho-Oncology
- Trial name
- Psychoeducatio (NCT07284030)
- Testing
- Web-Based Psychoeducation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Yasemin Nazli
Familial Melanoma, Fear of Cancer Recurrence
EMDR for Fear of Cancer Recurrence in Patients with Familial Melanoma: a Waiting List Control Trial
High fear of cancer recurrence (FCR) impacts patient's quality of life (QoL) and is prevalent among patients with familial melanoma.
- Conditions
- Familial Melanoma, Fear of Cancer Recurrence, Eye Movement Desensitization and Reprocessing, Psychological Intervention
- Trial name
- FAME (NCT06767332)
- Testing
- eye movement desensitization and reprocessing (EMDR)
- Where
- 2 sites in Netherlands
- Volunteers
- 30 people
- Sponsor
- Leiden University Medical Center
Barrett Esophagus, Barrett Esophagus Adenocarcinoma
A Study of Barrett's Esophagus Patients: Optimization of a Risk Model to Better Predict the Development of Cancer Recurrence and the Effect of Risk Profile Disclosure on Patient Quality of Life and Fear of Cancer
The goal of the study is: The collection of various tissue samples (blood, biopsies and "esophageal brushes") and their analysis.
- Conditions
- Barrett Esophagus, Barrett Esophagus Adenocarcinoma, Adenocarcinoma - GEJ, Gastroenterology
- Trial name
- Endeavor-2 (NCT07455422)
- Testing
- Risk profile disclosure
- Where
- 10 sites in Belgium, Denmark and 5 more
- Volunteers
- 266 people
- Sponsor
- University Hospital, Antwerp
Bladder Cancer, Quality of Life
Impacts and Testing of the "Multi-domains Active-living Program" in Operable Non-Muscle Invasive Bladder Cancer Patients
Among bladder cancer, the majority of them (70%) are non-muscle-invasive bladder cancer (NMIBC). The survival time is even longer in NMIBC. Patients with NMIBC receive surgery or transurethral resection of bladder tumor (TURBT).
- Trial name
- NCT05739968
- Testing
- Usual care + oncology case manager (OCM) care, Multi-domains Active-living Program (MAP) with e-health enhanced intervention + usual care + oncology case manager (OCM) care
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Cancer, Parent
Adapting The Fear Of Recurrence Therapy (FORT) for Parents and Establishing Acceptability and Feasibility
Clinical levels of fear of cancer recurrence (FCR) affect up to 59% of adult cancer survivors. Family caregivers experience equal or greater levels of FCR, which has been linked to lower quality of life and increased distress.
- Conditions
- Cancer, Parent, Fear of Cancer Recurrence, CBT
- Trial name
- Parent-FORT (NCT06872840)
- Testing
- Parent Fear of Recurrence Therapy (Parent-FORT)
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- University of Ottawa
Breast Cancer Susceptibility Gene (BRCA1) Mutation, BRCA2 Mutation
Cognitive Behavioral Therapy for Fear of Cancer Recurrence in Women With BRCA1/2 Gene
The goal of this clinical trial is to determine whether an adapted version of a current cognitive-behavioural group therapy (CBT) protocol for cancer survivors to the specific needs of women who are carriers of the BRCA1/2…
- Conditions
- Breast Cancer Susceptibility Gene (BRCA1) Mutation, BRCA2 Mutation, Fear of Cancer Recurrence
- Trial name
- CBT-FCRBRCA1/2 (NCT06817694)
- Testing
- Cognitive-behavioral group therapy
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- CHU de Quebec-Universite Laval
Lung Cancer, Breast Cancer
Screening and Care for Fear of Cancer Recurrence in Patients With Cancer at Institut Curie
The goals of this study is to establish the prevalence of severe forms of FCR in the oncology hospital setting, which will require a specific psychotherapeutic response.
- Trial name
- PDR-CARE (NCT07357311)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Institut Curie