Clinical trials: Feasibility
Acute Myeloid Leukemia
AML Electronic Decision Aid
The purpose of this study is to test the feasibility and preliminary efficacy of a novel electronic decision aid to improve AML patients' understanding of their illness, prognosis, and treatment options.
- Trial name
- NCT03442452
- Testing
- Electronic Decision Aid Tool
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Duke University
Abortion Early, Pregnancy Related
Mail Order Mifepristone Study
This study aims to evaluate the feasibility, acceptability, and effectiveness of dispensing mifepristone via a mail-order pharmacy.
- Trial name
- NCT03913104
- Testing
- Mifepristone
- Where
- 11 sites in United States
- Volunteers
- 536 people, healthy volunteers welcome
- Sponsor
- Daniel Grossman, MD
HIV (Human Immunodeficiency Virus), HPV
Feasibility Study Comparing One vs Two Probes for Thermal Ablation Among Cervical Cancer Screen Positive Women Living With HIV in C1001P-CS7 Zimbabwe
Cervical cancer disproportionately affects women in low- and middle-income countries (LMICs), particularly women living with HIV (WLWH) who have a 6-fold increased risk of cervical cancer compared to women in the general…
- Conditions
- HIV (Human Immunodeficiency Virus), HPV, Cervical Precancer, Cervical Neoplasia
- Trial name
- NCT07645352
- Testing
- Thermal ablation (TA) with 1 probe, Thermal ablation (TA) with 2 probes
- Where
- Zimbabwe
- Volunteers
- 300 people
- Sponsor
- Fred Hutchinson Cancer Center
Neoplasms
Safety, Feasibility and Cost-effectiveness of Genotype-directed Individualized Dosing of Fluoropyrimidines
In this study it will be determined whether the rate of severe toxicity associated with fluoropyrimidine treatment (capecitabine or 5-fluorouracil) can be significantly diminished by individualized dosing of fluoropyrimidines…
- Trial name
- NCT02324452
- Testing
- Fluoropyrimidine (capecitabine or 5-fluorouracil)
- Where
- 17 sites in Netherlands
- Volunteers
- 1,103 people
- Sponsor
- The Netherlands Cancer Institute
Systemic Sclerosis
Self-Guided Resilience-Building Energy Management to Enhance Well-being (RENEW) Intervention for People With Systemic Sclerosis (SSc)
The goal of this clinical trial is to gather information on the RENEW app used by people with scleroderma. Specifically, the researchers want to learn more about RENEW by collecting information about the rates of recruitment…
- Trial name
- RENEW (NCT07402863)
- Testing
- RENEW
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Michigan
Cancer
A Master Trial Assessing the Technical Feasibility of First-In-Human Real-Time Image Guided Radiation Therapy Methods
The goal of this clinical trial is to determine whether Real-Time Image Guided Radiation Therapy is a feasible method for radiation therapy delivery for patients with cancer.
- Trial name
- Real-Time IGRT (NCT06708221)
- Testing
- Real-Time Image Guided Radio Therapy (IGRT)
- Where
- Australia
- Volunteers
- 40 people
- Sponsor
- University of Sydney
Neuroendocrine Tumor
Use of Video Consultation in Follow-up Care for Patients With a Neuroendocrine Tumor: a Feasibility Study
Rationale: Patients with neuroendocrine tumors (NET) have a rare disease. Due to treating patients with a neuroendocrine tumor in 'NET knowledge centers' patients often have to travel long distances for follow-up visits at the…
- Trial name
- VIDEO-NET (NCT02147106)
- Testing
- Videoconsultation
- Where
- Netherlands
- Volunteers
- 26 people
- Sponsor
- University Medical Center Groningen
Breast Cancer
Feasibility Study of Intraoperative Imaging in Breast Cancer
For most breast cancer patients, surgery is the primary treatment. When patients undergo a lumpectomy, it is difficult for the surgeon to determine the extent of the tumor which results in incomplete tumor removal as determined…
- Trial name
- NCT02438358
- Testing
- LUM015, LUM 2.6 Imaging Device
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Lumicell, Inc.
Depression
Feasibility of Depression Care Management by E-mail
This study will test whether an electronic system that monitors and sends messages to help people with depression could be feasible, acceptable, and potentially effective as a treatment.
- Trial name
- NCT00755235
- Testing
- Depression care management by secure messaging
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- Kaiser Permanente
Mobility Limitation
Digitisation of the Timed Up and Go Test for the General Public
The question this feasibility study aims to answer is whether or not participants are able to accurately and reliably perform and self record the timed up and go test in a non-clinical environment using the Medopad application.
- Trial name
- NCT04229108
- Testing
- Medopad
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Andrew Gvozdanovic
Atrial Septal Defect, Atrial Fibrillation
Feasibility Study on the VERAFEYE System
The objective of the study is to evaluate the performance of the VERAFEYE System in subjects entitled to undergo a standard of care ablation or closure procedure.
- Conditions
- Atrial Septal Defect, Atrial Fibrillation, Atrial Arrhythmia, Left Atrial Appendage Closure
- Trial name
- LUMINIzE (NCT05931835)
- Testing
- VERAFEYE System
- Where
- Ireland
- Volunteers
- 18 people
- Sponsor
- LUMA Vision Ltd.
Myocardial Infarction
Early Versus Standard Access Cardiac Rehabilitation to Counter Ventricular Remodeling Post-MI (EVADE)
BACKGROUND: Cardiac rehabilitation (CR) is an outpatient chronic disease management program delivering secondary prevention, which is proven to reduce morbidity and mortality.
- Trial name
- EVADE (NCT03534817)
- Testing
- Early Access CR
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Saskatchewan
Caregiver Burden
ACT-CSP for Family Caregivers of Palliative Care Patients
The goal of the study is to test the feasibility, acceptability and preliminary efficacy of an acceptance and commitment therapy for supporting caregiver programme (ACT-CSP) on reduction of caregiver burden, anxiety and…
- Trial name
- NCT06221189
- Testing
- ACT-CSP
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Varicose Veins of Lower Limb
Feasibility Study of Ultrasound-guided Functional Remodeling of Lower Extremity Superficial Venous Valve
In this project, an exploratory study was conducted to perform in situ venous valve remodeling in vivo, evaluate venous valve function after surgery and conduct regular follow-up, collect relevant ultrasonic data before, during…
- Trial name
- NCT05914740
- Testing
- Ultrasound guided functional remodeling of lower extremity superficial vein valve
- Where
- China
- Volunteers
- 10 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Pain, Postoperative, Anesthesia, Regional
Comparison of the Efficiency of PENG Block and ESP Block Used for Postoperative Analgesia in Elective Hip Surgery
The aim of the study is to determine whether the traditional intravenous analgesia technique or the ultrasound-guided pericapsular nerve group block or the unilateral erector spina plane block technique is superior in…
- Conditions
- Pain, Postoperative, Anesthesia, Regional, Hip Surgery, Ultrasound-Guided
- Trial name
- NCT05802589
- Testing
- Lumbar Erector Spinae Plane Block, Pericapsular Nerve Group Block, no peripheral block
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Trakya University
Patient Transport, Respiratory Failure
HERMES: International Survey and Portable External Power Evaluation During Respiratory Support Transport
The HERMES Phase I-II study was a two-phase observational investigation designed to characterize contemporary practices and safety-related challenges associated with the transport of patients requiring advanced respiratory…
- Conditions
- Patient Transport, Respiratory Failure, Noninvasive Ventilation, High-Flow Nasal Oxygen
- Trial name
- HERMES (NCT07807189)
- Testing
- Portable External Power Supply
- Where
- 20 sites in United States, Chile and 12 more
- Volunteers
- 246 people
- Sponsor
- Medipol University
Gamification, Nutrition
Usability and Feasibility of the NutriQuest Application
The study is a pilot study (phase 2) that includes a usability study (phase 1). The aim of the study is to investigate the feasibility and usability of the healthy nutrition application and the effects on adherence to Modified…
- Conditions
- Gamification, Nutrition, Behavior Change
- Trial name
- NCT05884489
- Testing
- A gamified smartphone app-based eating behaviour intervention
- Where
- Belgium
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
Acute Ischemic Stroke and Transient Ischemic Attacks
Cardiac CT Angiography in Acute Stroke Imaging (SCOPE-CT)
Stroke can occur when a blood clot travels to the brain and blocks blood flow. In some patients, these blood clots may originate in the heart.
- Trial name
- SCOPE-CT (NCT07896889)
- Testing
- Cardiac CT Angiography
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Ottawa Hospital Research Institute
Obesity & Overweight
Healthy Eating for My Infant: A Community- Informed Infant Obesity Prevention Program Addressing the Impact of Maternal Mental Health on Eating and Feeding
Infants from low-income families are at increased risk for obesity, but obesity prevention programs tailored specifically to the needs of these infants are lacking.
- Trial name
- NCT07284108
- Testing
- Healthy Eating for My Infant (HEMI)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Multiple Sclerosis
Waking Hypnosis in the Treatment of MS-related Fatigue
The proposed study is a single-center, single-blind three-group randomized (1:1:1) controlled trial (RCT) comparing two hypnosis interventions to waitlist control efficacy for MS-related fatigue.
- Trial name
- POWER-UP (NCT04429789)
- Testing
- Active-Alert Hypnosis, Traditional Hypnosis
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Washington