Clinical trials: Feasibility Pilot Study, open to volunteers
Examination Phobia
Dogs Offering Guidance: Therapeutic Observation for Reducing Examination Anxiety (DOGTOR).
Physiotherapists work closely with patients to assess, diagnose and treat a variety of conditions. Thus, it is essential that education should assess these key competencies through both written examinations (to measure cognitive…
- Trial name
- NCT07817459
- Testing
- Canine Group
- Where
- Australia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- La Trobe University
Vaginal Stenosis, Radiation Therapy
Feasibility of Hyivy Device Post-Radiation for Pelvic Malignancies
Vaginal dilator therapy (VDT) with static dilators is often prescribed to patients following vaginal or pelvic radiation therapy.
- Conditions
- Vaginal Stenosis, Radiation Therapy, Cancer, Pelvic Pain
- Trial name
- NCT05648253
- Testing
- Hyivy Intravaginal Device
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Hyivy Health Inc
Congenital Heart Disease, Cardiac Output
UltraTrac for Cardiac Output Monitoring in Congenital Heart Disease
This pilot feasibility study will evaluate UltraTrac, an investigational noninvasive wearable device for continuous cardiac output monitoring, in patients with congenital heart disease.
- Conditions
- Congenital Heart Disease, Cardiac Output, Hemodynamic Monitoring, Pediatric Heart Disease
- Trial name
- UltraTrac (NCT07866573)
- Testing
- UltraTrac
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Minnesota
Safety Issues, Feasibility
A Pilot Study of Deep Cervical Lymphatic-venous Anastomosis in the Treatment of Alzheimer's Disease
Alzheimer's disease (AD) is the most prevalent form of dementia, affecting 3-4% of the population over a lifetime. It's characterized by abnormal Amyloid-beta (Aβ) and tau protein expression and accumulation in the central…
- Conditions
- Safety Issues, Feasibility, Therapeutic Value
- Trial name
- NCT06448442
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Postpartum Depression
Postpartum 1-Day CBT Pilot Study (Türkiye)
This pilot randomized controlled trial aims to evaluate the feasibility, acceptability, and preliminary effects of a culturally adapted, one-day online Cognitive Behavioral Therapy (CBT)-based group workshop for women with…
- Trial name
- NCT07267702
- Testing
- One-Day Online CBT-Based Workshop
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
HFrEF - Heart Failure With Reduced Ejection Fraction, Heart Failure
Pilot Study of StudyU for N-of-1 Trials in HFrEF Patients (N-of-1 App)
This study will look at whether using a phone app called StudyU can help people with Heart Failure with Reduced Ejection Fraction (HFrEF) reach their recommended dose on their beta blocker.
- Conditions
- HFrEF - Heart Failure With Reduced Ejection Fraction, Heart Failure, Heart Failure, Systolic, Heart Diseases
- Trial name
- N-of-1 App (NCT07252310)
- Testing
- beta blockers, StudyU Application
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Weill Medical College of Cornell University
Mental Disorder, Psychosocial Rehabilitation
CapExchange: A Pilot Feasibility Study of a Capacity-Exchange Programme for Mental Health Recovery
CapExchange is a psychosocial rehabilitation programme based on reciprocal exchange of capacities and services between service users and their community environment, grounded in the concepts of circular mutuality and micro-social…
- Trial name
- CapExchange (NCT07620418)
- Testing
- CapExchange
- Where
- Guadeloupe
- Volunteers
- 15 people
- Sponsor
- EPSM de la Guadeloupe
Breast Carcinoma
Prehabilitation for Improving Outcomes in Breast Cancer Patients Undergoing Neoadjuvant Systemic Treatment and Surgery
This clinical trial evaluates whether a prehabilitation program is feasible for breast cancer patients receiving neoadjuvant systemic treatment before surgery.
- Trial name
- NCT07819981
- Testing
- Aerobic Exercise, Bioelectric Impedance Analysis, Consultation
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- City of Hope Medical Center
Cerebral Palsy (CP), Unilateral Cerebral Palsy
tDCS and Bi-manual Training in Cerebral Palsy
Unilateral spastic cerebral palsy (USCP) is the most common subtype of cerebral palsy and significantly limits upper limb function.
- Conditions
- Cerebral Palsy (CP), Unilateral Cerebral Palsy, Spastic Cerebral Palsy (sCP)
- Trial name
- NCT07573865
- Testing
- Anodal tDCS
- Where
- Pakistan
- Volunteers
- 15 people
- Sponsor
- Riphah International University
Vestibulodynia, Vulvodynia
Integrated Care Pathway for Hormonally Mediated Vestibulodynia: a Feasibility and Acceptability Pilot
This single-arm pilot study evaluates whether an integrated six-month care pathway for women with persistent vestibular vulvar pain and suspected hormonally mediated vestibulodynia can be delivered as planned, and how…
- Conditions
- Vestibulodynia, Vulvodynia, Vulvar Vestibulitis
- Trial name
- HerAccess (NCT07908901)
- Testing
- HerAccess integrated care pathway
- Where
- 2 sites in Denmark
- Volunteers
- 35 people
- Sponsor
- HerAccess ApS
Disc Herniation
Discogen for Low Back Pain
This study will be a double-blinded, two-arm, prospective, randomized controlled pilot feasibility study in 40 evaluable subjects (20 in each arm) at one study site within the United States.
- Trial name
- NCT06611397
- Testing
- Discogen Low pulsed ultrasound treatment
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Columbia University
Feasibility Studies, Acceptability
Feasibility Study of a Relaxation and Guided Imagery Intervention Research Protocol for Use in School Settings.
The goal of this study is to gather information that (1) will be used to determine whether or not a research protocol for investigating the efficacy of a relaxation and guided imagery intervention for improving K-12 students'…
- Conditions
- Feasibility Studies, Acceptability, Pilot Study
- Trial name
- NCT07910695
- Testing
- Relaxation and Guided Imagery, Progressive Muscle Relaxation
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Pace University
Chronic Graft Versus Host Disease, Hematopoietic and Lymphatic System Neoplasm
Mindfulness Intervention to Reduce Patient Reported Symptoms in Patients With Chronic Graft-Versus-Host Disease
This clinical trial tests a mindfulness intervention, consisting of group sessions and an individual session, using mindfulness based stress reduction techniques, to reduce patient reported symptoms for patients with chronic…
- Conditions
- Chronic Graft Versus Host Disease, Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT07733141
- Testing
- Biospecimen Collection, Mindfulness Relaxation, Survey Administration
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- City of Hope Medical Center
Dietary and Lifestyle Behaviour Change
Personalised Behavioural Intervention in Cancer Screening Programmes
The aim of this clinical trial is to find out whether CANVIA can help adults improve dietary and lifestyle habits related to cancer prevention.
- Trial name
- CANVIA (NCT07722442)
- Testing
- Personalised baseline feedback report, CANVIA mobile app intervention, Additional health professional support
- Where
- Spain
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Respiration Failure, Cardio Vascular Disease
COMPARE-VENT Feasibility Pilot Study
Cardiac disease complicated by respiratory insufficiency comprises the most frequent indication for cardiac intensive care unit (CICU) admission, with nearly one-third patients requiring advanced respiratory support and over 20%…
- Conditions
- Respiration Failure, Cardio Vascular Disease, Cardiogenic Pulmonary Oedema, Critical Illness
- Trial name
- NCT07656259
- Testing
- Volume Controlled Mode, Pressure Controlled Mode
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Mayo Clinic
Insulin Resistance, Type 2 Diabetes
Alpelisib Challenge Test (ACT)
The goal of this study is to test a potentially easier method for measuring how much insulin a person is capable of producing than the current gold-standard method, the "hyperglycemic clamp." Participants will come in for a…
- Conditions
- Insulin Resistance, Type 2 Diabetes, Obesity & Overweight, Healthy Adult Participants
- Trial name
- NCT07778524
- Testing
- Alpelisib 300 mg, Alpelisib Challenge Test (ACT): Mixed Meal Tolerance Test (MMTT) after taking alpelisib, Hyperglycemic clamp
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Columbia University
Diffuse Midline Glioma, H3 K27-Altered
Focused Ultrasound Blood-Brain Barrier Opening in Pontine Diffuse Midline Glioma to Enhance Temozolomide Therapy: Pilot Feasibility Study (FIDES)
This study is for people (children and adults) with a rare and aggressive brain tumor called H3K27-altered diffuse midline glioma (DMG) located in the pons, a deep part of the brainstem.
- Trial name
- FIDES (NCT07562971)
- Testing
- Focused Ultrasound (FUS) Blood-Brain Barrier Opening, Temozolomide (TMZ)
- Where
- 2 sites in Netherlands
- Volunteers
- 20 people
- Sponsor
- UMC Utrecht
Frailty, Social Isolation in Older Adults
A Pilot Study to Explore the Feasibility of Navigator and Coach Support for Community Participation by Older People
Frailty is a multidimensional syndrome in which a person accumulates age-related deficits across life domains, increasingly including social components such as social isolation.
- Conditions
- Frailty, Social Isolation in Older Adults, Frailty in Older Adults
- Trial name
- ENGAGE (NCT07836465)
- Testing
- Navigation support, Coaching support
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Bastiaan Van Grootven
Caregiver, ICU Patients
Nurse-Led Educational Intervention for Caregivers of ICU Patients (Nurses For Family - N4F)
Admission of a loved one to the intensive care unit (ICU) is a highly stressful experience for family members and caregivers. Many caregivers report increased levels of anxiety, stress, and depressive symptoms, often due to…
- Trial name
- N4F (NCT07603219)
- Testing
- Nurse-Led Educational Intervention for Caregivers of ICU Patients (Nurses For Family - N4F)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Cancer, Cancer Survivors
Addressing Social Determinants of Health Among Metro Detroit Cancer Survivors
The goal of this screening study is to determine the feasibility of completing a social needs screening tool in participants who have a past or current cancer diagnosis and reside in Metro Detroit, Michigan.
- Conditions
- Cancer, Cancer Survivors, Gastrointestinal Cancers, Neuroendocrine Tumors
- Trial name
- NCT06908629
- Testing
- Implementation of social determinants of health screening and referral
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute