Clinical trials: Feasibility Studies
Opioid-use Disorder, Cocaine Use Disorder
Feasibility and Validation of a Standard Phenotyping Assessment Battery
The overall goal of this project is to collect preliminary data on psychosocial measures and behavioral performance comparing individuals with Opioid Use Disorder, Cocaine Use Disorder, dual diagnosis of Opioid and Cocaine Use…
- Conditions
- Opioid-use Disorder, Cocaine Use Disorder, Marijuana Use Disorder, Healthy Controls
- Trial name
- PhAB (NCT03495869)
- Where
- United States
- Volunteers
- 368 people
- Sponsor
- Virginia Commonwealth University
Asthma
A 24-Week Treatment Study to Compare Standard of Care Versus the eMDPI DS in Participants 13 Years or Older With Asthma
The primary objective of this study is to demonstrate the effectiveness of the Digital System (DS) in improving asthma control compared to the Standard of Care (SoC) group.
- Trial name
- CONNECT2 (NCT04677959)
- Testing
- Fluticasone propionate/salmeterol (FS), Albuterol, Standard of Care Asthma Medication
- Where
- 46 sites in United States
- Volunteers
- 427 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Type 1 Diabetes Mellitus
Feasibility Study of a Modular Control to Range System in Type 1 Diabetes Mellitus
In this protocol the investigators plan to demonstrate the feasibility of a modular insulin management system based on continuous glucose monitoring and targeted towards the avoidance of hypoglycemic and prolonged hyperglycemic…
- Trial name
- MDB003 (NCT01418703)
- Testing
- Closed Loop Control (CLC), Open Loop
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Virginia
Fallopian Tube Cancer, Ovarian Cancer
Autologous T Cells With or Without Cyclophosphamide and Fludarabine in Treating Patients With Recurrent or Persistent Advanced Ovarian Epithelial Cancer, Primary Peritoneal Cavity Cancer, or Fallopian Tube Cancer (Fludarabine Treatment Closed as of 12/01/2009)
RATIONALE: Giving colony-stimulating factors, such as G-CSF, helps stem cells move from the bone marrow to the blood so they can be collected.
- Conditions
- Fallopian Tube Cancer, Ovarian Cancer, Primary Peritoneal Cavity Cancer
- Trial name
- NCT00562640
- Testing
- filgrastim, therapeutic autologous lymphocytes, cyclophosphamide
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cancer
Virtual Reality to Promote Relaxation Prior to Simulation
The purpose of this study is to assess the feasibility of a pre-simulation virtual reality (VR) platform designed to promote relaxation for cancer patients planned for radiation therapy (RT).
- Trial name
- NCT06318338
- Testing
- Virtual Reality Program
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Fetal Alcohol Spectrum Disorders
Feasibility Study of the My Health Coach App for Adults With FASD
The purpose of this study is to test a new smartphone "app" for adults with fetal alcohol spectrum disorder (FASD). The app is called My Health Coach.
- Trial name
- NCT05604014
- Testing
- My Health Coach
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- University of Rochester
Prostate Cancer
Study Combining Imatinib Mesylate (Gleevec) With Sorafenib in Patients With Androgen-independent Prostate Cancer (AIPC)
Eligible patients will be enrolled in one of 4 cohorts where each cohort will allow 3 patients to be on study. Patients will receive both study drugs on escalated dosing schedule until the maximum of 400 mg PO BID is reached for…
- Trial name
- NCT00424385
- Testing
- Gleevec + Sorafenib
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Oncology Specialists, S.C.
Pelvic Pain, Chronic Pelvic Pain
Program to Overcome Pelvic Pain Study
To refine and evaluate the feasibility of procedures for a future full-scale efficacy trial of a group-based therapeutic yoga intervention versus physical conditioning (stretching and strengthening) intervention for women with…
- Conditions
- Pelvic Pain, Chronic Pelvic Pain, Recurrent Pelvic Pain
- Trial name
- POPPY (NCT04615247)
- Testing
- Yoga Program, Physical Conditioning Program
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- University of California, San Francisco
HIV Infections
Atazanavir and Lamivudine for Treatment Simplification
Objectives of the study: 1. To verify the safety of the study treatment, defined as the persistent control of the virus' replication at 48 weeks after the simplification to lamivudine + atazanavir with ritonavir. 2.
- Trial name
- AtLaS (NCT00885482)
- Testing
- Lamiduvine (Epivir), Atazanavir (Reyataz), Ritonavir (Norvir)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Catholic University of the Sacred Heart
Acute Orthopedic Injury
Toolkit for Optimal Recovery After Orthopedic Injury
This is a multi-site randomized feasibility trial of the Toolkit for Optimal Recovery after Orthopedic Injury (TOR), a mind-body program to prevent persistent pain and disability in at-risk patients with acute orthopedic injury…
- Trial name
- TOR (NCT04973696)
- Testing
- Toolkit for Optimal Recovery after Orthopedic Injury, Minimally Enhanced Usual Care (MEUC)
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Massachusetts General Hospital
Persistent Pulmonary Hypertension of the Newborn
Markers of Inflammation and Lung Recovery in ECMO Patients for PPHN
Respiratory failure in newborns is common and has high rates of death. Where conventional intensive care strategies have failed, newborn children are referred to treatment with Extra- Corporeal Membrane Oxygenation (ECMO).
- Trial name
- Mi-ECMO (NCT02940327)
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- University of Leicester
Heart Disease, Lung Disease
Evaluating the Use of Thromboelastography (TEG) in Patient's Requiring Extracorporeal Membrane Oxygenation (ECMO)
This is a pilot study that seeks to evaluate the feasibility and safety of using a TEG algorithm in addition to traditional laboratory tests to guide transfusion and coagulation management of ECMO patients.
- Trial name
- NCT02887820
- Testing
- Thromboelastograph
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Stephen Esper
Smoking Cessation
A Pilot Study Of Smoking Cessation Treatment Including Varenicline In Patients Scheduled For Planned Surgery
It is possible to offer smoking cessation treatment including varenicline to patients scheduled for elective surgery. This study will evaluate whether or not this will enable some patients to quit smoking for up to 4 weeks prior…
- Trial name
- NCT00889720
- Testing
- Varenicline
- Where
- 2 sites in France, Italy
- Volunteers
- 16 people
- Sponsor
- Pfizer
Heart Failure With Normal Ejection Fraction, Sleep Apnea
Adherence to ASV Therapy in Heart Failure With Preserved Ejection Fraction Feasibility Study
This study is designed to demonstrate feasibility of study conduct and that acceptable adherence to adaptive servo-ventilation (ASV) therapy can be achieved in recently hospitalized HFpEF patients with moderate to severe sleep…
- Trial name
- CAT-PEF (NCT03195660)
- Testing
- ASV Therapy
- Where
- 4 sites in United States, Germany
- Volunteers
- 6 people
- Sponsor
- ResMed
GERD, Acid Reflux, Treatment
Omega Cuff for GERD Feasibility Study
This clinical feasibility study is to evaluate the performance of the Omega-Cuff in the treatment of acid reflux for up to 15 patients with a 1-year follow-up period.
- Trial name
- NCT04793035
- Testing
- Omega-Cuff
- Where
- 3 sites in United States
- Volunteers
- 6 people
- Sponsor
- Aplos Medical
Body Fat Disorder
CoolSculpting and EMS for the Abdomen
Evaluate the use of Electromagnetic Muscle Stimulation as an adjunctive treatment to CoolSculpting.
- Trial name
- ECA (NCT03738891)
- Testing
- Zeltiq CoolSculpting System alone, Electromagnetic Muscle Stimulation alone, EMS followed by CoolSculping
- Where
- 4 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Depression, Anxiety
A Transdiagnostic Course for Common Mental Health Problems in Primary Care
This study investigates the feasibility of a transdiagnostic course that is intended to work for a large variety of patient groups with clinically significant depression or anxiety in primary care.
- Trial name
- NCT04522713
- Testing
- Behavioral activation, evidence-based sleep strategies including sleep restriction, exposure-based strategies, promotion of physical activity and recuperating activities, psychoeducational material
- Where
- 2 sites in Sweden
- Volunteers
- 91 people
- Sponsor
- Karolinska Institutet
Peripheral Pulmonary Nodules
Pilot Study of Navigational Bronchoscopy and Transthoracic Needle Biopsy
The goal of this study is to evaluate the feasibility and safety of navigation guided virtual transthoracic needle biopsy combined with navigational bronchoscopy for the diagnosis of peripheral pulmonary nodules (PPN).
- Trial name
- NCT02109458
- Testing
- Navigation guided bronchoscopy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Johns Hopkins University
Trichotillomania
Feasibility Study for Treating Trichotillomania With Wearable Device and App System
Trichotillomania is characterized by recurrent hair pulling resulting in hair loss causing significant distress and impairment which persists despite repeated attempts to stop.
- Trial name
- NCT04241120
- Testing
- Device and app system designed for participant to self-administer Habit Reversal Training, Reminder bracelet control condition
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- HabitAware Inc.
Acute Spinal Cord Injury
Spinal Cord Injury Neuroprotection With Glyburide
The purpose of this study is to determine the safety of using oral Glyburide in patients with acute traumatic cervical spinal cord injuries (SCI).
- Trial name
- SCING (NCT02524379)
- Testing
- Glyburide
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Ohio State University