Clinical trials: Feasibility Studies
Glioblastoma
Feasibility Study of Modified Atkins Ketogenic Diet in the Treatment of Newly Diagnosed Malignant Glioma
The purpose of this research study is to see if people can produce ketones in their blood with the modified Atkins diet. Modified Atkins diet is a diet that produces ketones in your blood by restricting carbohydrates to <20 grams…
- Trial name
- NCT03278249
- Testing
- Modified Atkins Ketogenic Diet
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Cincinnati
Type 1 Diabetes Mellitus, Physical Activity
Physical Activity in Children With Type 1 Diabetes Study
This study aims to test the feasibility of a physical activity intervention called the Steps To Active Kids (STAK) programme in children aged 9 - 11 years with Type 1 Diabetes Mellitus (T1DM).
- Trial name
- NCT02144337
- Testing
- Steps To Active Kids (STAK) programme
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- University of Nottingham
Type 2 Diabetes
A Study of the GI Sleeve for the Treatment of Type 2 Diabetes
The purpose of the study was to evaluate the safety and efficacy of the EndoBarrier Gastrointestinal Liner compared to sham control in subjects with Type 2 diabetes.
- Trial name
- NCT02709577
- Testing
- EndoBarrier Gastrointestinal Liner
- Volunteers
- 36 people
- Sponsor
- Morphic Medical Inc.
Invasive Breast Cancer
Pre-Surgical Intervention for Targeted Therapies for Breast Cancer
The purpose of this study is to determine the feasibility of a short term administration of a targeted therapy (i.e., anastrozole) in women with newly diagnosed early invasive or non invasive breast cancer during the interval…
- Trial name
- NCT01004744
- Testing
- Anastrozole
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Columbia University
Type 1 Diabetes Mellitus
Feasibility Study Using Zone-MPC Controller, HMS and Technosphere® Insulin Inhalation System From MannnKind Corp
This clinical trial is a feasibility study to assess the performance of an Artificial Pancreas (AP) device using the Artificial Pancreas System (APS©) platform for subjects with type 1 diabetes using rapid-acting insulin as well…
- Trial name
- NCT01874392
- Testing
- Investigational inhaled insulin (Technosphere), Artificial Pancreas (AP) device (APS©)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Sansum Diabetes Research Institute
Carcinoma of the Anal Canal
Concurrent Chemoradiation + 5-FU + Mitomycin-C in Anal Carcinoma
This research study is a Pilot Study. Pilot studies are conducted to see if it is practical to do this type of research ona larger scale in the future.
- Trial name
- NCT01858025
- Testing
- Pencil Beam scanning Radiation, 5-fluorouracil, Mitomycin-C
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital
Persistent or Permanent Non-valvular Atrial Fibrillation
Atrial Fibrillation (AF) Patients Not Taking Vitamin-K Antagonist (VKA)
The purpose of this study is to assess the safety and tolerability of AZD0837 in patients with atrial fibrillation who are unable or unwilling to take vitamin K antagonist therapy for up to 3 months.
- Trial name
- NCT00623779
- Testing
- AZD0837, Aspirin
- Where
- 38 sites in Denmark, Norway and 4 more
- Volunteers
- 128 people
- Sponsor
- AstraZeneca
Breast Cancer
Post-operative Radiation With IMRT in the Management of Stage IIB-III Breast Cancer
Research has shown that treatment with conventional radiation techniques and chemotherapy following mastectomy or breast conserving surgery has resulted in better rates of locoregional control and overall survival in stage…
- Trial name
- NCT00508352
- Testing
- Helical tomotherapy IMRT
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Ottawa Hospital Research Institute
Opaque Bottles, Conventional, Clear Bottles
Opaque Bottle Study
The proposed research aimed to conduct an intervention study assessing the effect of feeding mode (clear versus opaque bottle) on the quality and outcome of infant feeding interactions.
- Trial name
- NCT03711370
- Testing
- Clear Bottle, Opaque Bottle
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Colorectal Cancer
A Study in People With Colorectal Cancer to Test Whether Ezabenlimab or Pembrolizumab in Combination With BI 765063 Lead to Side Effects or Delays in Surgery
This study is open to people with newly diagnosed colorectal cancer. People who are scheduled for surgery can participate. People either get a medicine called BI 765063 combined with ezabenlimab or combined with pembrolizumab in…
- Trial name
- NCT05446129
- Testing
- Ezabenlimab, BI 765063, Pembrolizumab
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Boehringer Ingelheim
Type 1 Diabetes, Type 2 Diabetes
Feasibility Study of New Subcutaneous Glucose Sensor With Recording Devices
The purpose of Phase 3 Group is to evaluate the impact of acetaminophen on the performance of Guardian Sensor (3) during 11 days of wear (approximately 264 hours) in subjects with insulin requiring diabetes,18-75 years of age.
- Trial name
- NCT04020822
- Testing
- Guardian Sensor (3)
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- Medtronic MiniMed, Inc.
Extrahepatic Bile Duct Cancer, Nausea
Aprepitant in Preventing Nausea and Vomiting in Patients Undergoing Chemotherapy and Radiation Therapy for Pancreatic Cancer
This pilot clinical trial is studying how well aprepitant works in preventing nausea and vomiting in patients undergoing chemotherapy and radiation therapy for pancreatic cancer.
- Conditions
- Extrahepatic Bile Duct Cancer, Nausea, Vomiting, Stage II Pancreatic Cancer
- Trial name
- NCT01534637
- Testing
- aprepitant, gemcitabine hydrochloride, capecitabine
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Wake Forest University Health Sciences
Gastroparesis, Dyspepsia
Magnetically Controlled Capsule Endoscopy Feasibility Study in Gastric Motility
This is a feasibility study to assess the utility of magnetically controlled capsule endoscopy in the evaluation of gastroparesis and functional dyspepsia
- Trial name
- NCT05004012
- Testing
- Magnetically Controlled Capsule Endoscopy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Hypermetabolic Lymphadenopathy Mediastinum Lower, Posterior and Middle, Detected by PET-CT With 18F-FDG (PET)
Feasibility Study on the Contribution of Guided Puncture With Echoendoscopy
Impact of screening nodes mediastinal by PET, at different times of the management of cancer disease, remain unclear. Benefits of combined PET and puncture with echoendoscopy for the diagnosis subsequent therapeutic management…
- Trial name
- APOGEE (NCT01892501)
- Testing
- Guided punction of mediastinal lymphadenopathy by echoendoscopy, PET scan
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Institut Bergonié
Knee Osteoarthritis
Wearable Sensors in Knee OA
This is a single-arm clinical trial to investigate the outcome of exercise-based physical therapy in people with knee osteoarthritis through the use of wearable sensors.
- Trial name
- WESENS-OA (NCT04243096)
- Testing
- Exercise-based Physical Therapy
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Boston University Charles River Campus
Breastfeeding
Home-based Breastfeeding Peer Counselling Programme
A feasibility study is proposed in the current study as women who had given birth to their first babies recruited to a previous project specifically expressed the need for postnatal breastfeeding support from peer counsellors at…
- Trial name
- NCT03705494
- Testing
- Home-based peer counselling (web-based) intervention
- Where
- Hong Kong
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Prostate Cancer
Feasibility of Hormones and Radiation for Intermediate or High Risk Prostate Cancer
The purpose of this study is see if quality of life is improved in patients receiving oral hormone therapy compared to standard of care.
- Trial name
- NCT01342367
- Testing
- Bicalutamide, Dutasteride, Finasteride
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Chicago
Burn, Child
Virtual Reality Distraction for Procedural Pain Management and Anxiety in Children With Burn Injuries : A Pilot Study
Procedural pain is the most intense and often undertreated pain associated with burn injuries. The use of analgesics does not always provide optimal relief and is accompanied by several side effects.
- Conditions
- Burn, Child, Pain, Anxiety
- Trial name
- NCT02794103
- Testing
- Virtual Reality Distraction
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- St. Justine's Hospital
Nicotine Addiction
Effects of ABT-089 on Smoking Abstinence Symptoms and Reward
This Phase IIa within-subject, cross-over pilot study will evaluate the effects of ABT-089 (an experimental medication not approved by the FDA) when administered as 40mg oral once daily dose for 10 days, compared to placebo, on…
- Trial name
- NCT01756053
- Testing
- ABT-089
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Pennsylvania
Opioid Use, Opioid-use Disorder
Providing Suboxone and PrEP Using Telemedicine
The purpose of this study is to provide medication for opioid use disorder (MOUD) with buprenorphine and naloxone, or bup/nx, and pre-exposure prophylaxis (PrEP) for HIV prevention for persons who inject opioids accessing syringe…
- Conditions
- Opioid Use, Opioid-use Disorder, Risk Reduction, Hiv
- Trial name
- NCT04521920
- Testing
- Suboxone, PrEP
- Where
- 3 sites in United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Duke University