Clinical trials: Fed
Healthy
LEO 22811 - Single Dose Bioavailability Study of Tablet Versus Oral Solution in Healthy Subjects
The purpose of this phase 1 study is to determine the relative bioavailability and pharmacokinetics following single oral dose administration of LEO 22811 solution compared to LEO 22811 tablet in healthy male subjects as well as…
- Trial name
- NCT01211964
- Testing
- LEO 22811
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- LEO Pharma
Healthy
A Study to Assess the Food Effect on Bioavailability of Metformin/Gliclazide in Healthy Participants
This study will assess the food effect on bioavailability of Metformin/Gliclazide fixed dose combination tablet in fed and fasted state.
- Trial name
- NCT03467971
- Testing
- Metformin/Gliclazide Fixed Combination
- Where
- Mexico
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Merck KGaA, Darmstadt, Germany
Breast Cancer
Bioequivalency Study of Exemestane 25 mg Tablet Under Fed Conditions
The objective of this study was to prove the bioequivalence of Exemestane 25 mg tablet under fed conditions.
- Trial name
- NCT01331434
- Testing
- exemestane
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Pain
A Study of Whether 2 New Oral Formulations of a Strong Pain Killer Release the Same Amount of Drug Into the Body as the Marketed Medication
To determine whether two new oral formulations of a strong pain killer release the drug into the body in a similar pattern as the already marketed reference capsule formulation with or without food.
- Trial name
- NCT02089581
- Testing
- Active comparator MR2XXX, MRXXX, MR1XXX
- Where
- 2 sites in United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mundipharma Research Limited
Migraine
Bioequivalency Study of Naratriptan Hydrochloride 2.5 mg Under Fed Conditions
The objective of this study was to prove the bioequivalence of Naratriptan Hydrochloride Tablet under fed conditions.
- Trial name
- NCT01161654
- Testing
- naratriptan hydrochoride
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Healthy
Bioequivalence Study of Xian Risperdal Tablets Compared With Gurabo Risperdal Tablets Under Fasting and Fed Conditions in Chinese Healthy Participants
The primary purpose of this study is to assess the bioequivalence of Xian Risperdal compared with Gurabo Risperdal in Chinese healthy participants under fasting and fed conditions.
- Trial name
- NCT03220867
- Testing
- Risperidone: Xian Risperdal (test), Risperidone: Gurabo Risperdal (reference)
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Xian-Janssen Pharmaceutical Ltd.
Healthy
Venlafaxine Hydrochloride 150 mg Extended-Release Capsules Under Fed Conditions
The objective of this study was to compare the rate and extent of absorption of venlafaxine hydrochloride 150 mg extended-release capsules (test) versus Effexor® XR (reference) administered as 1 x 150 mg extended-release capsule…
- Trial name
- NCT01282801
- Testing
- Venlafaxine Hydrochloride, Effexor® XR
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Teva Pharmaceuticals USA
Prostatic Hyperplasia
Determine the Bioequivalence of Two Formulations of Tamsulosin HCl Capsules in Fed Male.
Two tamsulosin HClformulations will be tested in fed state
- Trial name
- NCT02417844
- Testing
- tamsulosin (Astellas), Tamsulosin HCL
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Prostatic Hyperplasia
Comparative Bioavailability of Two Fixed Dose Combination (FDC) Formulations of Dutasteride and Tamsulosin Hydrochloride Relative to Co-administration of Dutasteride With Tamsulosin Hydrochloride in Healthy Male Subjects Under Fed and Fasted States
This study will be an open-label, randomized, single dose, three way crossover study in healthy male subjects. The aim of the study is to evaluate the pharmacokinetic parameters of two formulations of a fixed dose combination…
- Trial name
- NCT02184585
- Testing
- Treatment sequence A, Treatment sequence B, Treatment sequence C
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy
Concor® Bioequivalence Study in Chinese Participants (Darmstadt-Nantong)
The purpose of this study is to assess is the bioequivalence (BE) of Concor 5 milligram (mg) tablets manufactured by Merck/China Nantong (test product) and Concor 5 mg tablets manufactured by Merck/Germany Darmstadt (reference…
- Trial name
- NCT05930808
- Testing
- First Test Concor (Fasted), First Reference Concor (Fasted), First Test Concor (Fed)
- Where
- China
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Healthy Male Volunteers
The Pharmacokinetic Study of the Fixed-dose Combination of Micronized Fenofibrate and Pitavastatin Ca
To evaluate the comparative pharmacokinetics and safety of fixed-dose combination versus coadministration of Lipilfen cap.160mg(micronized fenofibrate160mg) and Livalo tab.
- Trial name
- NCT02250976
- Testing
- Livasupril Cap.160/2mg, Lipilfen cap. 160mg, Livaro tab. 2mg
- Where
- South Korea
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Hanlim Pharm. Co., Ltd.
Type 2 Diabetes Mellitus
Sitagliptin/Metformin Fed Bioequivalence Study (0431A-080)
This study will demonstrate the bioequivalence of metformin after single dose administration of sitagliptin/metformin 50/500 mg fixed dose combination (FDC) tablet and concomitant administration of single doses of sitagliptin 50…
- Trial name
- NCT00929201
- Testing
- Sitagliptin phosphate/metformin hydrochloride FDC, Sitagliptin phosphate, Metformin hydrochloride
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
To Determine Bioequivalence Under Fed Conditions
Bioavailability Study of Leflunomide Tablets Under Fed Conditions
To compare the single-dose Bioavailability of Kali and Aventis
- Trial name
- NCT00653003
- Testing
- Leflunomide, ARAVA
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Par Pharmaceutical, Inc.
Embolism and Thrombosis
A Study to Compare Pharmacokinetic Parameters and Safety Profiles Between AD-109 and AD-1091
Primary endpoint of this study is to evaluate the pharmacokinetic characteristics of AD-109 in healthy male subjects.
- Trial name
- NCT05128591
- Testing
- Rivaroxaban 18mg Oral Tablet, Rivaroxaban 20 MG Oral Tablet
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Addpharma Inc.
Healthy
Bioequivalence Study of Ziprasidone HCL Capsules, 20 mg of Dr. Reddy's Under Fed Conditions
The objective of this study is to compare the rate and extent of absorption of ziprasidone 20 mg capsules versus Geodon 20 mg capsules under fed conditions.
- Trial name
- NCT01581879
- Testing
- Ziprasidone Hydrochloride
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Healthy
Sumatriptan Succinate 100 mg Tablets Under Non-Fasting Conditions
The objective of this study is to compare the rate and extent of absorption of sumatriptan from a test formulation of Sumatriptan Succinate 100 mg Tablets versus the reference Imitrex® 100 mg Tablets under fed conditions.
- Trial name
- NCT00846885
- Testing
- Sumatriptan Succinate, Imitrex®
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Teva Pharmaceuticals USA
Healthy Volunteers
A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components
The purpose of this study is to assess the bioequivalence of the fixed dose combination (two components combined in one tablet) of canagliflozin and metformin extended release (XR) tablet (dose of 2 X 50 mg/500 mg) with respect…
- Trial name
- NCT02065752
- Testing
- Canagliflozin, 100 mg, Metformin XR, 500 mg, CANA/MET XR FDC, Formulation 1, 50 mg/500 mg
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Healthy
Amlodipine 10 mg Tablets Under Fed Conditions
The objective of this study is to compare the rate and extent of absorption of amlodipine from a test formulation of Amlodipine Besylate Tablets, 10 mg versus the reference Norvasc® 10 mg Tablets under fed conditions.
- Trial name
- NCT00841815
- Testing
- Amlodipine Besylate, Norvasc®
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Teva Pharmaceuticals USA
Healthy
Fed Study of Midodrine HCl Tablets 5 mg and ProAmatine® Tablets 5 mg
The objective of this study was to investigate the bioequivalence of Mylan's midodrine HCl 5 mg tablets to Roberts ProAmatine® 5 mg tablets following a single, oral 5 mg (1 x 5 mg) dose administration under fed conditions.
- Trial name
- NCT00650013
- Testing
- Midodrine HCl Tablets 5 mg, ProAmatine® Tablets 5 mg
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc
Epilepsy, Bipolar Disorder
To Demonstrate the Relative Bioavailability of Divalproex Sodium 500 mg Delayed Release Tablets Under Fed Conditions
To demonstrate the relative bioavailability of Divalproex Sodium 500 mg delayed release tablets under fed conditions.
- Trial name
- NCT00913848
- Testing
- Divalproex Sodium 500 mg DR Tablets (Sandoz Inc., USA), Depakote 500 mg DR Tablets (Abbott Laboratories, USA)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sandoz