Clinical trials: Fed, open to volunteers
Spinal Stenosis Lumbar
Full-Endoscopic Decompression vs. Endoscopic Lumbar Fusion for Middle-Aged and Older Adults With Spinal Stenosis
Lumbar Spinal Stenosis (LSS) is a syndrome characterized by anatomical narrowing of the central canal, lateral recess, or intervertebral foramen of the lumbar spine, leading to compression of nerve roots, the cauda equina, and…
- Trial name
- NCT07482826
- Testing
- Full-Endoscopic Decompression, Endoscopic Lumbar Interbody Fusion
- Volunteers
- 176 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Growth
Preterm Infants Fed a Human Milk Fortifier
This is a double-blind, randomized, multi-center, controlled, parallel study to evaluate the growth and tolerance of preterm infants fed human milk fortifier (HMF).
- Trial name
- NCT05551975
- Testing
- Control Product, Experimental Product 1, Experimental Product 2
- Where
- 14 sites in United States
- Volunteers
- 321 people
- Sponsor
- Abbott Nutrition
LCAT Deficiency
LCAT (Lecithin Cholesterol Acyl Transferase) Natural History Study
The purpose of the LCAT (Lecithin cholesterol acyl transferase) Natural History Study (LCAT NHS) is to help identify people with a mutation in a gene called LCAT, collect and store information about their medical history and…
- Trial name
- LCAT NHS (NCT06217588)
- Testing
- Demographics, diagnosis type, genotype, lipid profile, renal function profile, treatment allocation, ophthalmology exam, country of residence.
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pennsylvania
Breast Feeding
Cannabidiol Into Breastmilk
Really few data published to date on the passage of CBD into breast milk. The investigators known that 17.5 percent of the French human being between 18 and 34 years old consume CBD and among this, nearly half are women.
- Trial name
- CBD-ALLT (NCT06589258)
- Testing
- Assessing maternal and lactational plasma CBD uptake at different stages of breastfeeding
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Fuchs' Endothelial Dystrophy, Cataract
The Effects of Ripasudil in Patients With FED Undergoing Femtosecond Laser Assisted Cataract Surgery
The purpose of this research is to investigate the effects of ripasudil administered as an ophthalmic solution in patients with FED after femtosecond laser assisted cataract surgery.
- Trial name
- NCT06048380
- Testing
- Ripasudil
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- Singapore Eye Research Institute
Oral Mucosal Integrity, Palliative Care
Oral Care Interventions in PEG-Fed Palliative Care Patients
This pilot randomized controlled trial will compare three oral care interventions in adult palliative care patients who receive enteral nutrition through a percutaneous endoscopic gastrostomy (PEG) tube.
- Conditions
- Oral Mucosal Integrity, Palliative Care, PEG Feeding
- Trial name
- PEG-ORAL (NCT07792473)
- Testing
- Ankaferd Hemostat, Benzydamine Hydrochloride 0.15% w/v oromucosal solution, Combined Oral Care Solution
- Volunteers
- 60 people
- Sponsor
- University of Yalova
Infant Growth
Growth and Health Efficacy of Novel Infant Formula : A Randomized Trial
Randomized, controlled study consisting of three parallel arms to investigate the effects of novel infant formula on growth, gut health, immune function, and sleep status in healthy infants and young children aged 12-18 months.
- Trial name
- NCT07534735
- Testing
- Investigational Formula 1, Investigational Formula 2
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Biostime (Changsha) Nutrition Foods Limited
Erectile Dysfunction
Hezkue®, Hezkue Turbo®, and Commercial Sildenafil Products in Fed Healthy Male Subject
The goal of this clinical trial is to compare how different sildenafil formulations are absorbed and tolerated in healthy adult males under fed conditions.
- Trial name
- NCT07117383
- Testing
- ASP-001.1, ASP-001, Commercial Sildenafil and Sildenafil/Tadalafil Products
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Aspargo Labs, Inc
Physical Fitness, Mitochondrial Function, Bioenergetics
Effects of Acute Exercise in Fasting and Fed States in Individuals With Different Aerobic Fitness Levels
The aim of this study is to investigate the effects of aerobic fitness level, feeding status, and acute exercise on whole-body metabolic fuel utilization and mitochondrial function in peripheral blood mononuclear cells (PBMCs) in…
- Conditions
- Physical Fitness, Mitochondrial Function, Bioenergetics, Mitochondria, Energy Metabolism
- Trial name
- NCT07813403
- Testing
- Acute Moderate-Intensity Cycling Exercise, Ad Libitum Mixed Meal
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Feeding and Eating Disorders of Childhood, Enteral Nutrition Dependence
Gut Microbiota Changes in Children Receiving Exclusive Enteral Nutrition With Compleat® Paediatric
This observational, prospective, single-center study aims to evaluate changes in the fecal microbiota of pediatric patients receiving exclusive enteral nutrition following the introduction of Compleat® Paediatric Nature Mix, an…
- Trial name
- COMPLEAT (NCT07816536)
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Establishment for Children and Adolescents in the Nantes Region
Necrotizing Enterocolitis, Premature
Fecal Calprotectin in Breastfed vs Formula-Fed Preterm Infants and NEC
This prospective observational study aims to evaluate fecal calprotectin levels as an early indicator of necrotizing enterocolitis in preterm infants and to compare levels between breastfed and formula-fed preterm infants at…
- Conditions
- Necrotizing Enterocolitis, Premature, Breast Feeding
- Trial name
- NCT07810543
- Volunteers
- 112 people
- Sponsor
- Assiut University
Infant Colic, Atopic Dermatitis
Use of Bifidobacterium Bifidum in Formula-Fed Infants With Colic, With or Without Atopic Dermatitis
The goal of this clinical trial is to evaluate whether daily probiotic supplementation with Bifidobacterium bifidum (Bifipral® drops) can reduce crying time in formula-fed infants aged 5 months or younger diagnosed with infant…
- Trial name
- NCT07754968
- Testing
- Bifidobacterium bifidum BFP19® and BFP29® (Bifipral®)
- Where
- Italy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Benign Prostatic Hyperplasia
A Study to Evaluate the Safety and Pharmacokinetics of AD-116 and AD-1161 in Healthy Adult Male Subjects
A Study to Evaluate the Safety and Pharmacokinetics of AD-116 and AD-1161 Under Fed Conditions in Healthy Adult Male Subjects
- Trial name
- NCT07444385
- Testing
- AD-116, AD-1161
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Addpharma Inc.
Obesity, Exercise
Fasted vs. Fed State Exercise
Although many medications exist for both heart disease and obesity, cost, lack of access for all people, side effects and the desire for a more natural solution have left many people seeking lifestyle treatments such as exercise.
- Conditions
- Obesity, Exercise, Weight Loss
- Trial name
- NCT07487090
- Testing
- 16 week exercise intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Arkansas Colleges of Health Education
Diabetes Mellitus, Type 1
Fasted Exercise Training in Type 1 Diabetes (FED-T1D)
This study compares aerobic exercise training performed before breakfast (i.e., in the fasted state) to similar training performed after breakfast in people with type 1 diabetes. Training will take place over 12 weeks.
- Trial name
- FED-T1D (NCT06748963)
- Testing
- Fasted Exercise, Postprandial Exercise
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Stable Neonates, Receiving Total Parenteral Nutrition (TPN)
Phenylalanine, Methionine and Histidine Requirements in TPN Fed Neonates
This is a single center project assessing the requirements for three essential amino acids in TPN fed neonates. Using the Carbon Oxidation method (indicator amino oxidation and direct amino acid oxidation method), the…
- Trial name
- NCT05562310
- Testing
- Total parenteral nutrition (TPN). This is total nutrition provided by central vein.
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- The Hospital for Sick Children
Iron Deficiency Anemia
Donor Breast Milk 2
The goal of this clinical trial is to determine the serum ferritin level and hematocrit level in very preterm infants receiving donor breast milk(DBM) with an early iron supplementation protocol .
- Trial name
- NCT07816601
- Testing
- Ferrous Sulfate Oral Product
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- AdventHealth
Plasmodium Vivax Malaria, Vivax Malaria
Tafenoquine Drug Levels in Small Children
This study is an open label, single arm, pharmacokinetic trial. A total of 20 participants (children ≤12kg and >28 days old) will be enrolled.
- Trial name
- TQP (NCT07835321)
- Testing
- Chloroquine, Tafenoquine
- Where
- 2 sites in Thailand, Vietnam
- Volunteers
- 20 people
- Sponsor
- University of Oxford
Diabete Mellitus
A Study to Evaluate the Pharmacokinetics and Safety Between "BR3006" and Co-administration of "BR3006A", "BR3006B", and "BR3006C" in Healthy Adult Volunteers (Fed)
This was an open-label, randomized, fed, single-dose, 2-sequence, 2- period crossover study to evaluate the pharmacokinetics and safety between single oral administration of "BR3006" and co-administration of "BR3006A", "BR3006B,"…
- Trial name
- NCT07083401
- Testing
- Dapagliflozin 10 mg/Pioglitazone 30 mg/Metformin HCl 1000 mg, Dapagliflozin 10 mg, Pioglitazone 30 mg
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Tinnitus
A Study of the Safety and Efficacy of TRTL-913 in Healthy Volunteers (Part A) and in Adults With Tinnitus (Part B)
This study will consist of two parts. Double blind Part A will assess the safety, tolerability, and pharmacokinetics of 7 days of dosing in healthy adults, while open label Part B will evaluate the safety, tolerability, and…
- Trial name
- NCT07777549
- Testing
- TRTL-913
- Where
- 10 sites in Australia, New Zealand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tortugas Neuroscience, Inc.