Clinical trials: Fed, open to volunteers
Cow Milk Protein Allergy
Growth And Safety Outcomes In Infants With Cow´s Milk Protein Allergy (CMPA) Fed A Novel Extensively Hydrolyzed Formula (eHF)
Growth and safety Outcomes in infants with CMPA fed a novel extensively hydrolyzed formula.
- Trial name
- NCT07711938
- Testing
- New generation eHF, Commercial eHF
- Volunteers
- 410 people
- Sponsor
- Société des Produits Nestlé (SPN)
Myeloma Multiple
Bioequivalence Studies of Dasatinib 100 Mg
A bioequivalence study of Dasatinib will be carried out in 46 healthy subjects, in fed condition, following the complete replicated design, randomized, comparative of 2 sequences, 2 study formulations, in a single dose of 100 mg…
- Trial name
- BE-Dasatinib (NCT05944783)
- Testing
- Dasatinib 100 MG
- Where
- Colombia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Centro de Atencion e Investigacion Medica
LCAT Deficiency
LCAT (Lecithin Cholesterol Acyl Transferase) Natural History Study
The purpose of the LCAT (Lecithin cholesterol acyl transferase) Natural History Study (LCAT NHS) is to help identify people with a mutation in a gene called LCAT, collect and store information about their medical history and…
- Trial name
- LCAT NHS (NCT06217588)
- Testing
- Demographics, diagnosis type, genotype, lipid profile, renal function profile, treatment allocation, ophthalmology exam, country of residence.
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pennsylvania
Chronic Graft Versus Host Disease
Study to Compare the Plasma Concentration of Belumosudil Given as an Oral Suspension and as a Tablet to Healthy Adult Male Participants
The purpose of this open-label, randomized, cross-over, Phase 1, 2-treatment, 2-period, 2-sequence study is to assess the bioequivalence of belumosudil oral suspension compared with belumosudil tablet in healthy male participants…
- Trial name
- NCT07726914
- Testing
- Belumosudil
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Sanofi
Fuchs' Endothelial Dystrophy, Cataract
The Effects of Ripasudil in Patients With FED Undergoing Femtosecond Laser Assisted Cataract Surgery
The purpose of this research is to investigate the effects of ripasudil administered as an ophthalmic solution in patients with FED after femtosecond laser assisted cataract surgery.
- Trial name
- NCT06048380
- Testing
- Ripasudil
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- Singapore Eye Research Institute
Healthy Adult Participants
Replacing Meat With Legumes in a Mediterranean Diet
This study will investigate whether replacing grass-fed organic meat with legumes within a Mediterranean diet affects cardiometabolic health in healthy adults.
- Trial name
- MED-SWAP (NCT07847996)
- Testing
- Mediterranean Diet With Grass-Fed Organic Meat, Mediterranean Diet With Legumes
- Volunteers
- 40 people
- Sponsor
- Universidad Francisco de Vitoria
Diabetes Mellitus, Type 1
Fasted Exercise Training in Type 1 Diabetes (FED-T1D)
This study compares aerobic exercise training performed before breakfast (i.e., in the fasted state) to similar training performed after breakfast in people with type 1 diabetes. Training will take place over 12 weeks.
- Trial name
- FED-T1D (NCT06748963)
- Testing
- Fasted Exercise, Postprandial Exercise
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Healthy
Safety and Pharmacokinetics of Extrato de Cannabis Sativa GreenCare
The goal of this Phase I clinical trial is to assess the pharmacokinetic availability and safety and tolerability profile of Extrato de Cannabis sativa GreenCare 79.14 mg/mL.
- Trial name
- NCT06807762
- Testing
- Cannabis oil
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- GreenCare Pharma
Tinnitus
A Study of the Safety and Efficacy of TRTL-913 in Healthy Volunteers (Part A) and in Adults With Tinnitus (Part B)
This study will consist of two parts. Double blind Part A will assess the safety, tolerability, and pharmacokinetics of 7 days of dosing in healthy adults, while open label Part B will evaluate the safety, tolerability, and…
- Trial name
- NCT07777549
- Testing
- TRTL-913
- Where
- New Zealand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tortugas Neuroscience, Inc.
Gastrointestinal Tolerance, Gastrointestinal Symptoms
Gastrointestinal Symptoms and Tolerance in Infants Fed Goat or Cow's Milk-based Infant Formula
This randomized controlled double-blind study will compare the effect of a commercially available goat milk formula to a cow's milk formula on gastrointestinal symptoms and tolerance, and infections in infants.
- Conditions
- Gastrointestinal Tolerance, Gastrointestinal Symptoms, Infections, Quality of Life
- Trial name
- MESK-2 (NCT07342972)
- Testing
- Goat milk-based infant formula, Cow's milk-based infant formula
- Where
- Saudi Arabia
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Ausnutria Hyproca B.V.
Post-ICU Patients Fully Enterally Fed
Assessment of Nutrient Absorption in Enterally Fed Post-intensive Care Unit Patients Using Bomb Calorimetry: do the Calories Stick
This study focuses on understanding how well patients who have recovered from an ICU stay absorb nutrients when receiving enteral (tube) feeding.
- Trial name
- STICKY (NCT06923813)
- Testing
- caloric intake measurement, stool sample collection, energy expenditure measurement
- Where
- 2 sites in Belgium
- Volunteers
- 20 people
- Sponsor
- Universitair Ziekenhuis Brussel
Healthy Volunteers, Pharmacokinetics
Food Effect on PK of DW-1021 (Pelubiprofen 45 mg / Tramadol 45.9 mg) in Healthy Adults
This is a Phase 1, open-label, single-dose crossover study designed to evaluate the effect of food on the pharmacokinetics of DW-1021, a fixed-dose combination tablet containing pelubiprofen 45 mg and tramadol 45.9 mg.
- Conditions
- Healthy Volunteers, Pharmacokinetics, Food Effect in Healthy Volunteers
- Trial name
- DW-1021F (NCT07060209)
- Testing
- DW-1021
- Where
- 2 sites in Vietnam
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Haiphong University of Medicine and Pharmacy
Moderate-to-severe Benign Prostatic Hyperplasia (BPH)
Bioequivalence Study of AJU-G721 and G721R in Healthy Adult Volunteers Under Fed Conditions
To evaluate and compare the safety and pharmacokinetic profiles of "AJU-G721" (test drug) and "G721R" (reference drug) in healthy adult male subjects.
- Trial name
- NCT07643233
- Testing
- Test Drug, Reference Drug
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- AJU Pharm Co., Ltd.
Healthy, Healthy Donors
Bioequivalence Study of Pentoxifylline 400 Mg in Healthy Subjects Under Fasting and Fed Conditions
Two bioequivalence studies of Pentoxifylline will be carried out in 40 healthy subjects, the first in a fasting condition 40 healthy subjects, the first in fasting condition and the second in postprandial condition.
- Trial name
- Pentoxifylline (NCT06823362)
- Testing
- Pentoxifylline
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centro de Atencion e Investigacion Medica
Oral Mucosal Integrity, Palliative Care
Oral Care Interventions in PEG-Fed Palliative Care Patients
This pilot randomized controlled trial will compare three oral care interventions in adult palliative care patients who receive enteral nutrition through a percutaneous endoscopic gastrostomy (PEG) tube.
- Conditions
- Oral Mucosal Integrity, Palliative Care, PEG Feeding
- Trial name
- PEG-ORAL (NCT07792473)
- Testing
- Ankaferd Hemostat, Benzydamine Hydrochloride 0.15% w/v oromucosal solution, Combined Oral Care Solution
- Volunteers
- 60 people
- Sponsor
- University of Yalova
Type2 Diabetes Mellitus
A Study to Evaluate the Safety and Pharmacokinetics of Dapagliflozin, Linagliptin, and Metformin in Healthy Adults: Fed State Study
To Evaluate the Safety and Pharmacokinetics of Dapagliflozin, Linagliptin, and Metformin in Healthy Adults after taking the drugs with food (fed state).
- Trial name
- NCT07044765
- Testing
- Comparator 1, Comparator 2, Test Drug
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- AJU Pharm Co., Ltd.
Focal Cortical Dysplasia, Epilepsy
Mos-FED (Mosaicism in Focal Epilepsy Cortical Dysplasia Tissue)
Focal cortical dysplasia (FCD) is a malformation of brain development, the most common cause of drug-resistant epilepsy and often caused by mutations in mammalian target of rapamycin (mTOR) pathway genes.
- Trial name
- MosFED (NCT06053671)
- Testing
- Blood and nasal swab sampling
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- King's College Hospital NHS Trust
Spinal Stenosis Lumbar
Full-Endoscopic Decompression vs. Endoscopic Lumbar Fusion for Middle-Aged and Older Adults With Spinal Stenosis
Lumbar Spinal Stenosis (LSS) is a syndrome characterized by anatomical narrowing of the central canal, lateral recess, or intervertebral foramen of the lumbar spine, leading to compression of nerve roots, the cauda equina, and…
- Trial name
- NCT07482826
- Testing
- Full-Endoscopic Decompression, Endoscopic Lumbar Interbody Fusion
- Volunteers
- 176 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Influenza, Acute Respiratory Viral Infections
Safety and Pharmacokinetics of Ingavirin Forte, Capsules, 90 mg + 20 mg (Valenta Pharm JSC, Russia) Compared With Ingavirin, Capsules, 90 mg, Under Fasting and Fed Conditions.
This study aims to evaluate the safety and pharmacokinetic profile of the active ingredients Ingavirin forte, capsules, 90 mg + 20 mg (Valenta Pharm JSC, Russia) relative to single-entity Drug Ingavirin, capsules, 90 mg following…
- Trial name
- NCT07645534
- Testing
- Ingavirin forte, capsules, 90 mg + 20 mg, Ingavirin, capsules, 90 mg
- Where
- Russia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Valenta Pharm JSC
Effect of Food
The Food Effect on Pharmacokinetics Study of QLC1101 in Healthy Subjects
This randomized, open-label, three-period, three-treatment crossover Phase I clinical trial is designed to evaluate the pharmacokinetic profile of QLC1101 capsules administered as a single oral dose under fasting conditions…
- Trial name
- NCT06980909
- Testing
- QLC1101
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Qilu Pharmaceutical Co., Ltd.