Clinical trials: Feeding Intolerance
Feeding Intolerance in Preterm Infants
The Effect of Lactase-Treated Feeds on Feeding Intolerance in Preterm Infants
The purpose of this study is to evaluate whether adding lactase enzyme to milk feeds can improve feeding tolerance in preterm neonates.
- Trial name
- NCT07784062
- Testing
- Lactase enzyme, Distilled water
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Necrotizing Enterocolitis, Very Low Birth Weight Infants
Splanchnic Oxygenation After the First Enteral Feed in Preterm Infants: Prediction of Feeding Tolerance.
Enteral nutrition of preterm and intrauterine growth-restricted (IUGR) infants is still a challenge for neonatologists. Due to the immaturity of the gastrointestinal tract, preterm infants are at high risk of developing feeding…
- Trial name
- NIRS-SO (NCT02383264)
- Where
- Italy
- Volunteers
- 61 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bronchopulmonary Dysplasia, Feeding Intolerance
Gastric Feeding Versus Transpyloric Feeding in Infants with Severe Bronchopulmonary Dysplasia, a Crossover Study
Hospitalized infants with severe bronchopulmonary dysplasia (BPD) and feeding intolerance will be randomized to 2 weeks of continuous gastric feeding or continuous transpyoloric feeding.
- Trial name
- NCT06821776
- Testing
- Gastric feeding, Transpyloric feeding
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Le Bonheur Children's Hospital
Disorder of Stomach Function and Feeding Problems in Newborn, Feeding and Eating Disorders of Childhood
Effect of Early Oral Triple Viable Bifidobacterium Intestinal Flora in Preterm
Gut of newborn preterm is sterile, immediately by the mother and the surrounding environment from microbial colonization. As the effects of diet, intestinal flora is rapidly changed.
- Trial name
- NCT02060084
- Testing
- a control group, a probiotic-supplemented group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wang Hua
Premature Newborn, Necrotizing Enterocolitis
Defining Normal Citrulline Levels as a Diagnostic Tool for Screening of Gastrointestinal Disease in Premature Infants
Since the first description of citrulline as a potential marker for intestinal function in 1998, its use has been investigated in a variety of disease processes including Short Bowel Syndrome, Celiac disease, chemotherapy and…
- Trial name
- NCT01062828
- Testing
- Citrulline samples
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Miami
Preterm Neonates and Feeding Intolerance, Necrotizing Enterocolitis
Effect of Oral N-Acetyl Cysteine in Prevention of Necrotizing Enterocolitis in Preterm Neonates With Feeding Intolerance
necrotizing enterocolitis is a dangerous disease that may be fatal especially in preterm neonates, the early features of the disease are symptoms of feeding intolerance and interruption of the baby's feeding plan , so…
- Conditions
- Preterm Neonates and Feeding Intolerance, Necrotizing Enterocolitis, Oral N-acetyl Cysteine
- Trial name
- Oral NAC (NCT06202911)
- Testing
- oral n-acetyl cysteine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Aortic Aneurysm, Gastrointestinal Dysfunction
Gastrointestinal Dysfunction in Aortic Surgery Patients
The goal of this observational study is to determine the association of gastrointestinal dysfunction through the Gastrointestinal Dysfunction Scale (GIDS) tool and serum concentrations of citrulline and Intestinal fatty-acid…
- Conditions
- Aortic Aneurysm, Gastrointestinal Dysfunction, Aortic Diseases, Enteral Feeding Intolerance
- Trial name
- NCT06514170
- Testing
- No intervention
- Where
- Mexico
- Volunteers
- 114 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Gestational Diabetes Mellitus in Pregnancy, Glucose Intolerance During Pregnancy
Effects of a Non-nutritive Sweetener Reduction Intervention in Pregnancy and Lactation on Maternal and Infant Outcomes
The effects of consuming non-nutritive sweeteners (NNS) during pregnancy and lactation on infant obesity and cardiometabolic disease risk are not well understood.
- Conditions
- Gestational Diabetes Mellitus in Pregnancy, Glucose Intolerance During Pregnancy, Non-nutritive Sweeteners Consumption in Pregnancy and/or Lactation
- Trial name
- NCT06548828
- Testing
- NNS Restriction Intervention, Control Intervention
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- George Washington University
Enteral Feeding Intolerance (EFI)
Efficacy, Safety, and Pharmacokinetics (PK) Study of Ulimorelin in Patients With Enteral Feeding Intolerance (EFI): The PROMOTE Trial
The purpose of this study is to evaluate the effect Ulimorelin in patients with enteral feeding intolerance.
- Trial name
- PROMOTE (NCT02784392)
- Testing
- Ulimorelin, Metoclopramide
- Where
- 5 sites in United States, Netherlands and 1 more
- Volunteers
- 120 people
- Sponsor
- Lyric Pharmaceuticals
Refractory Enteral Feeding Intolerance, Gut Microbiota
Gut Microbiota Structure, Functional and Metabolic Profiles, and Composite Biomarkers in ICU Adults With Refractory Enteral Feeding Intolerance
Some adults in the intensive care unit (ICU) cannot receive enough nutrition through a feeding tube because of persistent digestive problems, even after standard measures to improve feeding.
- Conditions
- Refractory Enteral Feeding Intolerance, Gut Microbiota, Metabolic Profiles
- Trial name
- NCT07864844
- Testing
- Naturally Occurring Exposures
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
PreDiabetes, Impaired Glucose Tolerance
High FODMAP Diet With Metformin in preDM
This is a prospective, double blinded, randomised cross over feeding trial examine high or low FODMAP diet in combination with metformin on postprandial glucose responses and gastrointestinal tolerability and gut microbiota…
- Trial name
- NCT05628584
- Testing
- High FODMAP diet with metformin, Low FODMAP diet with metformin
- Where
- Hong Kong
- Volunteers
- 26 people
- Sponsor
- Elaine Chow
Mechanical Ventilation Complication, Enteral Feeding Intolerance
Gastric Ultrasound to Monitor Gastric Residual Volume
It is currently recommended to start enteral nutrition early in intensive care unit children receiving invasive or non-invasive mechanical ventilation.
- Trial name
- GASTRIPED (NCT04119089)
- Testing
- Gastric ultrasound
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Hospices Civils de Lyon
Critical Illness, Enteral Nutrition Intolerance
Predictive Value of Gastrointestinal Blood Flow for Enteral Nutrition Intolerance in Critically Ill Patients
This study aims to explore the correlation between gastrointestinal blood flow and the incidence of enteral nutrition intolerance (ENI) and its symptoms in critically ill patients, construct and compare predictive models…
- Conditions
- Critical Illness, Enteral Nutrition Intolerance, Enteral Nutrition Feeding, Prediction Models
- Trial name
- NCT07521111
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ruijin Hospital
Enteral Nutrition
Feeding Intolerance Risk Prediction Model in Patients With Enteral Nutrition Through Nasogastric Tube
To explore the risk factors of enteral feeding intolerance in critically ill patients, build a risk prediction model and verify it, in order to provide reference for early identification and screening of high-risk groups
- Trial name
- NCT05900167
- Testing
- enteral nutrition
- Volunteers
- 442 people
- Sponsor
- Xiao Jie Chen
Critical Illness, Enteral Nutrition
Optimizing Enteral Nutrition Regimen for Critically Ill Patients
Clinical Trial The goal of this clinical trial is to learn whether different enteral feeding cycles (18-hour, 20-hour, or standard 24-hour continuous feeding) improve outcomes for critically ill ICU patients who need tube…
- Conditions
- Critical Illness, Enteral Nutrition, Ventilator Associated Pneumonia, Hyperglycemia
- Trial name
- NCT07270939
- Testing
- 20-Hour Cycled Enteral Nutrition with a 4-Hour Fasting Window, 18-Hour Cycled Enteral Nutrition with a 6-Hour Fasting Window
- Volunteers
- 150 people
- Sponsor
- Hamad Medical Corporation
Appetitive Behavior, Individual Difference
The Influence of Fat Perception on Satiety From Consumption of Reduced Fat Snacks
The present study aims to investigate the effect of fat level and fat type of a snack on self-reported satiety and associated biomarkers. The relevant individual differences will also be investigated.
- Conditions
- Appetitive Behavior, Individual Difference, Food Sensitivity, Food Preferences
- Trial name
- NCT03585920
- Testing
- Expanded Corn Snack
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Reading
Blood Transfusion Complication, Necrotizing Enterocolitis
Splanchnic Oxygenation Response to Feeds in Preterm Neonates: Effect of Red Blood Cell Transfusion
Since 1987, red blood cell (RBC) transfusions have been proposed as a potential risk factor for necrotizing enterocolitis (NEC), which is one of the most severe gastrointestinal complications of prematurity.
- Conditions
- Blood Transfusion Complication, Necrotizing Enterocolitis, Enteral Feeding Intolerance, Preterm Infant
- Trial name
- NIRS_RBC (NCT03643458)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Septic Shock
Splanchnic Perfusion Monitoring in Septic Shock Using Doppler Ultrasound
evaluation whether splanchnic Doppler ultrasound indices (SMA resistive index, portal vein pulsatility fraction, hepatic artery resistive index/flow parameters) can: 1.
- Trial name
- NCT07698834
- Volunteers
- 80 people
- Sponsor
- Assiut University
Growth, Necrotizing Enterocolitis
Bovine Colostrum as a Fortifier Added to Human Milk for Preterm Infants
Very preterm infants (<32 weeks gestation) with very low birth weight (VLBW, <1500 g) show immaturity of organs and have high nutrient requirements forgrowth and development.
- Conditions
- Growth, Necrotizing Enterocolitis, Late-Onset Sepsis, Feeding Intolerance
- Trial name
- FortiColos (NCT03537365)
- Testing
- Bovine Colostrum (BC) / intervention group, FM85 / control group
- Where
- 7 sites in Denmark
- Volunteers
- 252 people
- Sponsor
- Per Torp Sangild
Intervention, Food Allergy
Healthy Meals: A Restaurant-based Study to Promote Healthy and Allergy Adapted Diet
This study evaluates the effect of a multicomponent intervention applied to restaurant staff about training and nutritional quality of menu improvement, in order to promote a healthy diet and a better management of allergies and…
- Conditions
- Intervention, Food Allergy, Food Preferences, Food Intolerance
- Trial name
- HealthyMeals (NCT03826576)
- Testing
- Multicomponent intervention
- Where
- Spain
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili