Clinical trials: Feeding and Eating Disorders
Anxiety, Depression
Neuromodulation Enhanced Cognitive Restructuring: A Proof of Concept Study
Psychological treatments are effective, but take a long time and can be burdensome. Therefore, avenues to optimize behavioral treatments are needed.
- Conditions
- Anxiety, Depression, Personality Disorders, Trauma and Stress-related Disorders
- Trial name
- NCT02573246
- Testing
- Cognitive Restructuring, rTMS
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Duke University
Anorexia Nervosa, Osteoporosis
Transdermal Estrogen in Older Premenopausal Women With Anorexia Nervosa
Decreased bone strength is a common and serious medical problem present in many women with anorexia nervosa. Women with decreased bone strength are more likely to suffer broken bones than women with normal bone strength.
- Trial name
- 1180 (NCT02475265)
- Testing
- estradiol 0.045 mg/levonorgestrel 0.015mg
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Massachusetts General Hospital
Major Depressive Disorder
A Personalized Approach to Effects of Affective Bias Modification on Symptom Change and Rumination
This study evaluates the effect of a computerized intervention for depressive symptoms called Affective Bias Modification (ABM).
- Trial name
- NCT04137367
- Testing
- Affective bias modification
- Where
- Norway
- Volunteers
- 108 people
- Sponsor
- University of Oslo
Binge Eating Disorder
Follow-Up Extension to the Family Study of Binge Eating Disorder
This study involves a 2.5 and 5 year follow-up interview for individuals who participated in the initial family study of binge eating disorder.
- Trial name
- NCT00777634
- Testing
- No intervention.
- Where
- United States
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Binge-Eating Disorder, Obesity
Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Maintenance Treatment
This study will test the effectiveness of lisdexamfetamine (LDX) medication as a maintenance therapy for the treatment of binge-eating disorder (BED) in patients with obesity.
- Trial name
- NCT03926052
- Testing
- Lisdexamfetamine Dimesylate
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Yale University
Rumination, Depression
Adolescent Mindfulness Mobile App Study (RCT)
Rumination involves focusing on negative emotions repeatedly and is a risk factor for developing depression, anxiety, and self-injury. These negative outcomes increase in adolescence.
- Conditions
- Rumination, Depression, Anxiety, Self-Injurious Behavior
- Trial name
- AMMASRCT (NCT03900416)
- Testing
- Mindfulness App
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Lawrence University
Contraceptive Usage, Overweight or Obesity
A 6-month Observational Study on Combined Oral Contraceptives and Body Weight in Pre-Menopausal Women With Overweight or Obesity
Approximately 15 million women of reproductive age women in the United States have overweight or obesity and use the combined estrogen and progestin oral contraceptive pill (COC).
- Conditions
- Contraceptive Usage, Overweight or Obesity, Body Weight Changes, Appetitive Behavior
- Trial name
- NCT05061472
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
Eating Disorders
Leveraging Social Media to Identify and Connect Teens With Eating Disorders to a Mobile Guided Self-Help Mobile Intervention
Clinical or subclinical eating disorders (EDs) impact 10% of individuals in their lifetime and are marked by significant functional impairment, early mortality, chronicity, and emotional distress.
- Trial name
- NCT04636840
- Testing
- Space From Body and Eating Concerns- Teen
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- Washington University School of Medicine
Eating Disorders
Effectiveness of Olanzapine Versus Placebo in Treating Outpatients With Anorexia Nervosa
This study will evaluate the effectiveness of the antipsychotic medication olanzapine in treating outpatients with anorexia nervosa.
- Trial name
- NCT00692185
- Testing
- Olanzapine
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- New York State Psychiatric Institute
Anorexia Nervosa
Bone Loss in Women With Anorexia Nervosa
Women with Anorexia Nervosa have been found to have low bone density. The study will determine whether administration of low doses of a natural hormone, testosterone and/or risedronate, a medication to help prevent bone breakdown…
- Trial name
- NCT00089843
- Testing
- Testosterone, Actonel (risedronate)
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Massachusetts General Hospital
Anorexia Nervosa
Effect Of Biomechanical Stimulation On Skeletal Health In Adolescent And Young Women With Anorexia Nervosa
This study will evaluate the effects of a novel, non-pharmacologic intervention for the prevention of deleterious changes in bone density and strength in adolescents with anorexia nervosa (AN), a disease commonly treated with…
- Trial name
- NCT01100567
- Testing
- Low-magnitude mechanical stimulation platform
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Boston Children's Hospital
Binge Eating Disorder
Binge Eating Disorder Treatment Study
The main objective of the proposed study is to determine whether the effectiveness of a group therapy treatment for Binge Eating Disorder (BED) is improved and attrition reduced by optimally matching women with BED who have high…
- Trial name
- NCT00848367
- Testing
- Group Psychodynamic Interpersonal Psychotherapy
- Where
- Canada
- Volunteers
- 102 people
- Sponsor
- Ottawa Hospital Research Institute
Food Neophobia, Picky Eating
Weighted Blanket to Treat Anxiety Related to Trying New Foods the Pediatric Population
This small experimental pilot study addresses the knowledge gap related to the use of weighted blankets for children with anxiety related to food and eating.
- Conditions
- Food Neophobia, Picky Eating, Avoidant Restrictive Food Intake Disorder, Anxiety State
- Trial name
- Food Anxiety (NCT06420232)
- Testing
- weighted blanket
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Anorexia Nervosa, Eating Disorders
Fluoxetine to Prevent Relapse and Enhance Psychological Recovery in Women With Anorexia Nervosa
This study will evaluate the effectiveness of fluoxetine versus placebo in reducing the rate of relapse of anorexia nervosa (AN) and enhancing the psychosocial and behavioral recovery of people who have been treated for AN.
- Trial name
- NCT00288574
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- New York State Psychiatric Institute
Binge-Eating Disorder, Obesity
Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Medication Change for Non-Responders
This study will test the relative efficacy and effectiveness of the combination of naltrexone and bupropion (NB) medication as a treatment for binge-eating disorder (BED) in patients with obesity.
- Trial name
- NCT03946111
- Testing
- Naltrexone and Bupropion
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Yale University
Obesity, Eating Behavior
Influence of a Monopoly Game on Subtle Behaviors
This project will investigate the influence of experimentally manipulated perceived social standing on eating behavior and obesity risk.
- Trial name
- NCT02470949
- Testing
- Low Social Status, High Social Status
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Mild Cognitive Impairment, Obesity
Time Restricted Eating for Metabolic and Psychological Optimization
Obesity and related metabolic comorbidities have been associated with more than a 4-fold increased risk of incident cognitive impairment, including Alzheimer's disease and related dementias (ADRD).
- Trial name
- TEMPO (NCT05997316)
- Testing
- Time restricted eating
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of North Carolina, Chapel Hill
Feeding Disorders, Specific Phobia
D-cycloserine and Treatment of Feeding Disorders
The proposed study represents the first attempt to systematically investigate the use of DCS as an adjunct to behavioral intervention to address chronic food aversion through an randomized control drug trial in children treated…
- Trial name
- NCT01923896
- Testing
- Behavioral Intervention, d-cycloserine (DCS)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Emory University
Binge Eating Disorder
SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder
The primary objective of the study is to demonstrate the efficacy of SPD489 compared with placebo in adults (18 55 years of age inclusive) with moderate to severe Binge Eating Disorder at Visit 8 (Weeks 11 and 12) as measured by…
- Trial name
- NCT01718483
- Testing
- SPD489 (Lisdexamfetamine dimesylate)
- Where
- 50 sites in United States, Germany and 2 more
- Volunteers
- 383 people
- Sponsor
- Shire
Anorexia Nervosa, Constipation
The Role of Lactobacillus Reuteri in Children and Adolescents With Anorexia Nervosa
The aim of this study is to investigate whether Lactobacillus reuteri could have a beneficial role in treatment of children and adolescents with Anorexia nervosa who develop motility disorder due to the malnutrition regarding the…
- Trial name
- NCT02004288
- Testing
- Lactobacillus reuteri Protectis DSM17938
- Where
- Croatia
- Volunteers
- 31 people
- Sponsor
- BioGaia AB